Thierry Cresteil

Summary

Affiliation: Avenue de la Terrasse
Country: France

Publications

  1. ncbi request reprint Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship
    Thierry Cresteil
    Centre National de la Recherche Scientifique Unité Mixte Recherche 8532, Villejuif, France
    Drug Metab Dispos 30:438-45. 2002
  2. ncbi request reprint Quantitative liquid chromatographic determination of sanguinarine in cell culture medium and in rat urine and plasma
    Henri Hoellinger
    CNRS UPR 2301, Institut de Chimie des Substances Naturelles, Avenue de la Terrasse, 91198 Cedex, Gif sur Yvette, France
    J Chromatogr B Analyt Technol Biomed Life Sci 799:195-200. 2004
  3. ncbi request reprint Phenotyping-genotyping of alternatively spliced genes in one step: study of CYP3A5*3 polymorphism
    Florent Busi
    ICSN CNRS UPR2301, 91198 Gif sur Yvette, France
    Pharmacogenet Genomics 15:433-9. 2005
  4. ncbi request reprint In vitro oxidative metabolism study of (-)-rhazinilam
    Anne Décor
    Institut de Chimie des Substances Naturelles, CNRS, Gif sur Yvette, France
    Bioorg Med Chem 14:1558-64. 2006
  5. pmc Dexamethasone as a probe for vinorelbine clearance
    Florent Puisset
    EA3035, Institut Claudius Regaud, Toulouse, France
    Br J Clin Pharmacol 60:45-53. 2005
  6. ncbi request reprint CYP3A5 mRNA degradation by nonsense-mediated mRNA decay
    Florent Busi
    ICSN, CNRS UPR2301, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Mol Pharmacol 68:808-15. 2005
  7. ncbi request reprint In vitro metabolism study of buprenorphine: evidence for new metabolic pathways
    Nicolas Picard
    Department of Medical Pharmacology, University of Limoges, France
    Drug Metab Dispos 33:689-95. 2005
  8. ncbi request reprint Dexamethasone as a probe for docetaxel clearance
    Florent Puisset
    Institut Claudius Regaud, Universite Paul Sabatier, 31052 Toulouse, France
    Cancer Chemother Pharmacol 54:265-72. 2004
  9. ncbi request reprint In vitro metabolism of ethoxidine by human CYP1A1 and rat microsomes: identification of metabolites by high-performance liquid chromatography combined with electrospray tandem mass spectrometry and accurate mass measurements by time-of-flight mass spectro
    Alain Deroussent
    IFR54, Institut Gustave Roussy, Pavillon de Recherche, 94805 Villejuif, France
    Rapid Commun Mass Spectrom 18:474-82. 2004
  10. ncbi request reprint Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5
    Nicolas Picard
    Department of Pharmacology and Toxicology, University Hospital, 87042 Limoges, France
    Ther Drug Monit 26:600-8. 2004

Collaborators

  • Alain Deroussent
  • N Picard
  • Florent Busi
  • Florent Puisset
  • Adrien Boularot
  • Anne Décor
  • Henri Roche
  • Etienne Chatelut
  • Florence Dalenc
  • Henri Hoellinger
  • Marina Tinel
  • Thierry Meinnel
  • Carmela Giglione
  • Rodolphe Alves de Sousa
  • Sylvain Petit
  • Isabelle Artaud
  • Frédéric Dardel
  • Yann Duroc
  • Valéry Larue
  • Françoise Guéritte
  • Olivier Baudoin
  • Jamal Ouazzani
  • Angele Chiaroni
  • Nicolas Lekieffre
  • Delphine Bellocq
  • Odile Thoison
  • Pierre Tisnes
  • Isabelle Lochon
  • Christine Chevreau
  • Isabelle Hennebelle
  • Micheline Re
  • Joëlle Azéma
  • Thierry Lafont
  • Muriel Poublanc
  • Ravindra Pratap Singh
  • Johny Elkahwaji
  • Dominique Pessayre
  • Alain Berson
  • Philippe Beaune

Detail Information

Publications12

  1. ncbi request reprint Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship
    Thierry Cresteil
    Centre National de la Recherche Scientifique Unité Mixte Recherche 8532, Villejuif, France
    Drug Metab Dispos 30:438-45. 2002
    ....
  2. ncbi request reprint Quantitative liquid chromatographic determination of sanguinarine in cell culture medium and in rat urine and plasma
    Henri Hoellinger
    CNRS UPR 2301, Institut de Chimie des Substances Naturelles, Avenue de la Terrasse, 91198 Cedex, Gif sur Yvette, France
    J Chromatogr B Analyt Technol Biomed Life Sci 799:195-200. 2004
    ..This analytical HPLC method is specific, linear and reproducible in all media and is suitable for quantitative determination of sanguinarine in biological fluids...
  3. ncbi request reprint Phenotyping-genotyping of alternatively spliced genes in one step: study of CYP3A5*3 polymorphism
    Florent Busi
    ICSN CNRS UPR2301, 91198 Gif sur Yvette, France
    Pharmacogenet Genomics 15:433-9. 2005
    ..For the CYP3A5 gene, the genotype, the level of expression and the proportion of alternatively spliced products were determined in a single reaction without DNA sequencing...
  4. ncbi request reprint In vitro oxidative metabolism study of (-)-rhazinilam
    Anne Décor
    Institut de Chimie des Substances Naturelles, CNRS, Gif sur Yvette, France
    Bioorg Med Chem 14:1558-64. 2006
    ..All isolated metabolites were markedly less active than rhazinilam in vitro, which might explain its in vivo inactivity...
  5. pmc Dexamethasone as a probe for vinorelbine clearance
    Florent Puisset
    EA3035, Institut Claudius Regaud, Toulouse, France
    Br J Clin Pharmacol 60:45-53. 2005
    ..To assess the value of using dexamethasone as an in vivo probe for predicting vinorelbine clearance (CL)...
  6. ncbi request reprint CYP3A5 mRNA degradation by nonsense-mediated mRNA decay
    Florent Busi
    ICSN, CNRS UPR2301, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Mol Pharmacol 68:808-15. 2005
    ..Therefore, in these carriers, induction is unlikely to switch on the phenotypic CYP3A5 expression in carriers of CYP3A5*3/*3...
  7. ncbi request reprint In vitro metabolism study of buprenorphine: evidence for new metabolic pathways
    Nicolas Picard
    Department of Medical Pharmacology, University of Limoges, France
    Drug Metab Dispos 33:689-95. 2005
    ..Incubation of BUP or Nor-BUP with HLM led to the formation of new metabolites, identified by tandem mass spectrometry as being hydroxy-BUP and hydroxy-Nor-BUP. Hydroxy-BUP was produced by the CYP 3A, but not the 2C isoforms...
  8. ncbi request reprint Dexamethasone as a probe for docetaxel clearance
    Florent Puisset
    Institut Claudius Regaud, Universite Paul Sabatier, 31052 Toulouse, France
    Cancer Chemother Pharmacol 54:265-72. 2004
    ....
  9. ncbi request reprint In vitro metabolism of ethoxidine by human CYP1A1 and rat microsomes: identification of metabolites by high-performance liquid chromatography combined with electrospray tandem mass spectrometry and accurate mass measurements by time-of-flight mass spectro
    Alain Deroussent
    IFR54, Institut Gustave Roussy, Pavillon de Recherche, 94805 Villejuif, France
    Rapid Commun Mass Spectrom 18:474-82. 2004
    ..When 12-ethoxyfagaronine was incubated under the same conditions as ethoxidine, m(2) was formed, thus supporting the proposal that 12-ethoxyfagaronine is the primary oxidative product of ethoxidine...
  10. ncbi request reprint Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5
    Nicolas Picard
    Department of Pharmacology and Toxicology, University Hospital, 87042 Limoges, France
    Ther Drug Monit 26:600-8. 2004
    ..MPA might compete with other drugs on CYP3A because of its high therapeutic concentrations, although this was not the case for cyclosporin and to only a small extent for tacrolimus...
  11. ncbi request reprint Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA
    Marina Tinel
    Institut National de la Santé et de la Recherche Médicale INSERM Unité 481, Faculte de Medecine Xavier Bichat, 16 rue Henri Huchard, 75018, Paris, France
    J Hepatol 39:171-8. 2003
    ..Several cytochromes P450 (CYPs) are expressed in differentiated hepatocytes, but downregulated in growth-stimulated cells. We determined the signals involved in CYP downregulation by epidermal growth factor (EGF)...
  12. ncbi request reprint Discovery and refinement of a new structural class of potent peptide deformylase inhibitors
    Adrien Boularot
    UPR2355, Centre National de la Recherche Scientifique, Batiment 23, 1 Avenue de la Terrasse, F 91198 Gif sur Yvette Cedex, France
    J Med Chem 50:10-20. 2007
    ....