Affiliation: University of Helsinki
- Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's diseasePia Runeberg-Roos
Institute of Biotechnology, University of Helsinki, PB 56 Viikinkaari 5D, FIN 00014, Finland Electronic address
Neurobiol Dis 96:335-345. 2016..The new NRTN variants may help solve the major problem of inadequate distribution of NRTN in human brain tissue...
- Phytepsin, a barley vacuolar aspartic proteinase, is highly expressed during autolysis of developing tracheary elements and sieve cellsP Runeberg-Roos
Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Finland
Plant J 15:139-45. 1998..This is the first evidence that a vacuolar aspartic proteinase, in analogy to cathepsin D in animals, may play a role in the active autolysis of plant cells...
- RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surfaceP Runeberg-Roos
Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Helsinki, Finland
Oncogene 26:7909-15. 2007..Taken together, our data demonstrate that the oncogenic precursor of RET(MEN 2B) is phosphorylated, interacts with adapter proteins and induces downstream signalling from the ER...
- Glycosylation of phytepsin and expression of dad1, dad2 and ost1 during onset of cell death in germinating barley scutellaP Lindholm
Institute of Biotechnology, Viikki Biocenter, Program of Plant Molecular Biology, P O Box 56, FIN 00014 University of Helsinki, Finland
Mech Dev 93:169-73. 2000..Northern analysis of germinating scutella show that the expression of only dad1 is declining before onset of DNA fragmentation. In contrast to this, the expression of both dad2 and ost1 increase before onset of DNA fragmentation...