Affiliation: University of Helsinki
- Inhibition of human NK cell function by valinomycin, a toxin from Streptomyces griseus in indoor airA Paananen
Department of Pathology, Haartman Institute, FIN 00014 University of Helsinki, Finland
Infect Immun 68:165-9. 2000..Thus, valinomycin in very small doses may profoundly alter the immune response by reducing NK cell cytotoxicity and cytokine production...
- Inhibition of human natural killer cell activity by cereulide, an emetic toxin from Bacillus cereusA Paananen
Department of Pathology, Haartman Institute, University of Helsinki, Finland
Clin Exp Immunol 129:420-8. 2002..As the emesis causing concentration of cereulide is around 10 microg/kg of total body mass, our results suggest that emesis causing or even lower doses of cereulide may also have a systemic natural killer cell suppressive effect...
- IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12S Matikainen
Department of Microbiology, National Public Health Institute, Helsinki, Finland
Eur J Immunol 31:2236-45. 2001..Our results demonstrate that IFN-alpha and IL-18 are important innate cytokines in inducing NK cell IFN-gamma production...