Carita M Eklund

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. ncbi Proinflammatory cytokines in CRP baseline regulation
    Carita M Eklund
    Department of Microbiology and Immunology, University of Tampere, Medical School, 33520 Tampere, Finland
    Adv Clin Chem 48:111-36. 2009
  2. pmc C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall cancer risk
    C M Eklund
    Department of Microbiology and Immunology, University of Tampere, Biokatu 6, Tampere 33520, Finland
    Br J Cancer 100:1846-51. 2009
  3. ncbi C-reactive protein genetics is associated with carotid artery compliance in men in The Cardiovascular Risk in Young Finns Study
    C Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, 33014 University of Tampere, Finland
    Atherosclerosis 196:841-8. 2008
  4. ncbi Polymorphism of the C-reactive protein gene is associated with mortality in bacteraemia
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, Finland
    Scand J Infect Dis 38:1069-73. 2006
  5. ncbi Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, FI 33014 Tampere, Finland
    Eur Cytokine Netw 17:131-5. 2006
  6. ncbi Epistatic effect of C-reactive protein (CRP) single nucleotide polymorphism (SNP) +1059 and interleukin-1B SNP +3954 on CRP concentration in healthy male blood donors
    C Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, FIN 33014, Tampere, Finland
    Int J Immunogenet 32:229-32. 2005
  7. ncbi Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, Tampere, Finland
    Eur Cytokine Netw 14:168-71. 2003
  8. ncbi Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians
    Riikka Rontu
    Laboratory of Atherosclerosis Genetics, Tampere University Hospital, Centre for Laboratory Medicine and Department of Clinical Chemistry, University of Tampere, Medical School, Finland
    Clin Endocrinol (Oxf) 64:265-70. 2006
  9. ncbi Epistatic effect of TLR4 and IL4 genes on the risk of asthma in females
    Kati Adjers
    Department of Microbiology and Immunology, Medical School, University of Tampere, Tampere, Finland
    Int Arch Allergy Immunol 138:251-6. 2005
  10. ncbi Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study
    Mika Kivimaki
    Arterioscler Thromb Vasc Biol 27:978-9. 2007

Collaborators

Detail Information

Publications13

  1. ncbi Proinflammatory cytokines in CRP baseline regulation
    Carita M Eklund
    Department of Microbiology and Immunology, University of Tampere, Medical School, 33520 Tampere, Finland
    Adv Clin Chem 48:111-36. 2009
    ....
  2. pmc C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall cancer risk
    C M Eklund
    Department of Microbiology and Immunology, University of Tampere, Biokatu 6, Tampere 33520, Finland
    Br J Cancer 100:1846-51. 2009
    ..CRP alleles previously found to protect against increased CRP levels are now suggested to be associated with metastatic PC, indicated by elevated PSA...
  3. ncbi C-reactive protein genetics is associated with carotid artery compliance in men in The Cardiovascular Risk in Young Finns Study
    C Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, 33014 University of Tampere, Finland
    Atherosclerosis 196:841-8. 2008
    ..Men carrying the SNP -286 allele C had increased CAC after adjusting for risk factors. These data suggest that the presence of high producer CRP genotype is deleterious to carotid elasticity in men...
  4. ncbi Polymorphism of the C-reactive protein gene is associated with mortality in bacteraemia
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, Finland
    Scand J Infect Dis 38:1069-73. 2006
    ..These results suggest that mortality from Streptococcus pneumoniae may be associated with polymorphism of the promoter region of the CRP gene...
  5. ncbi Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, FI 33014 Tampere, Finland
    Eur Cytokine Netw 17:131-5. 2006
    ....
  6. ncbi Epistatic effect of C-reactive protein (CRP) single nucleotide polymorphism (SNP) +1059 and interleukin-1B SNP +3954 on CRP concentration in healthy male blood donors
    C Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, FIN 33014, Tampere, Finland
    Int J Immunogenet 32:229-32. 2005
    ..These polymorphisms might be predictive markers of persons prone to cardiovascular diseases...
  7. ncbi Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, Tampere, Finland
    Eur Cytokine Netw 14:168-71. 2003
    ..72 mg/l), and composite genotype analysis of IL1B-511/IL1B + 3954 supported this finding. Our findings suggest that in healthy people, basal CRP levels are regulated by IL1B but not by IL6 genetics...
  8. ncbi Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians
    Riikka Rontu
    Laboratory of Atherosclerosis Genetics, Tampere University Hospital, Centre for Laboratory Medicine and Department of Clinical Chemistry, University of Tampere, Medical School, Finland
    Clin Endocrinol (Oxf) 64:265-70. 2006
    ..The aim of the present study was to establish whether APOE genotype is related to plasma concentrations of CRP and lipids, or longevity among nonagenarians...
  9. ncbi Epistatic effect of TLR4 and IL4 genes on the risk of asthma in females
    Kati Adjers
    Department of Microbiology and Immunology, Medical School, University of Tampere, Tampere, Finland
    Int Arch Allergy Immunol 138:251-6. 2005
    ..We examined whether the polymorphisms of the TLR4 (A/G at +896) and IL4 (C/T at -590) showed an epistatic effect on the risk of asthma or atopy...
  10. ncbi Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study
    Mika Kivimaki
    Arterioscler Thromb Vasc Biol 27:978-9. 2007
  11. ncbi Variants in the CRP gene as a measure of lifelong differences in average C-reactive protein levels: the Cardiovascular Risk in Young Finns Study, 1980-2001
    Mika Kivimaki
    Department of Epidemiology and Public Health, Faculty of Biomedical Sciences, University College London, London, United Kingdom
    Am J Epidemiol 166:760-4. 2007
    ..These findings support the assumption that the above genetic variants define groups with long-term differences in circulating CRP levels...
  12. ncbi Relationship between leptin and C-reactive protein in young Finnish adults
    Liisa A Viikari
    Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20521 Turku, Finland
    J Clin Endocrinol Metab 92:4753-8. 2007
    ..Leptin and C-reactive protein (CRP) concentrations are increased in inflammation, and both have been linked to increased risk for cardiovascular diseases...
  13. ncbi Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
    Ian P M Tomlinson
    Molecular and Population Genetics Laboratory, Imperial Cancer Research Fund, 44, Lincoln s Inn Fields, London WC2A 3PX, UK
    Nat Genet 30:406-10. 2002
    ..Our results provide clues to the pathogenesis of fibroids and emphasize the importance of mutations of housekeeping and mitochondrial proteins in the pathogenesis of common types of tumor...