Eeva Auvinen

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. doi Diagnostic and Prognostic Value of MicroRNA in Viral Diseases
    Eeva Auvinen
    Department of Virology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 3, POB 21, 00014, Helsinki, Finland
    Mol Diagn Ther 21:45-57. 2017
  2. doi Altered expression of ezrin, E-Cadherin and β-Catenin in cervical neoplasia
    E Auvinen
    Department of Virology, University of Helsinki, Helsinki, Finland
    Neoplasma 60:56-61. 2013
  3. ncbi Human papillomavirus 16 in a heart transplant recipient
    E Auvinen
    Department of Virology, Haartman Institute of Helsinki University Helsinki University Central Hospital, Helsinki, Finland
    Transplant Proc 34:1281-2. 2002
  4. ncbi Human papillomavirus type 16 E5 protein colocalizes with the antiapoptotic Bcl-2 protein
    E Auvinen
    Department of Virology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Arch Virol 149:1745-59. 2004
  5. ncbi High prevalence of HPV among female students in Finland
    Eeva Auvinen
    Department of Virology, HUSLAB Clinical Microbiology and Haartman Institute, University of Helsinki, Helsinki, Finland
    Scand J Infect Dis 37:873-6. 2005
  6. ncbi Regulation of ezrin localization by Rac1 and PIPK in human epithelial cells
    Eeva Auvinen
    Department of Virology, Haartman Institute, University of Helsinki, and HUSLAB Clinical Microbiology, Helsinki University Central Hospital, Helsinki, Finland
    Exp Cell Res 313:824-33. 2007
  7. ncbi Repeated human papillomavirus DNA findings among female university students
    E Auvinen
    Department of Virology, HUSLAB Clinical Microbiology and Haartman Institute, University of Helsinki, Helsinki, Finland
    Int J STD AIDS 18:839-41. 2007
  8. doi Simultaneous BK Polyomavirus (BKPyV)-associated nephropathy and hemorrhagic cystitis after living donor kidney transplantation
    Ilkka Helantera
    Transplantation and Liver Surgery, University of Helsinki and Helsinki University Hospital, PO Box 372, FI 00029HUS, Helsinki, Finland Electronic address
    J Clin Virol 76:4-7. 2016
  9. doi BK virus viremia in a well-HLA-matched kidney transplant population mainly on low-dose cyclosporine-based immunosuppression
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Transplant 26:E596-601. 2012
  10. doi High-level JCPyV viruria after kidney transplantation-Clinical and histopathological findings
    Ilkka Helantera
    Transplantation and Liver Surgery, University of Helsinki and Helsinki University Hospital, PO Box 372, FI 00029 HUS, Helsinki, Finland Electronic address
    J Clin Virol 85:75-79. 2016

Collaborators

Detail Information

Publications26

  1. doi Diagnostic and Prognostic Value of MicroRNA in Viral Diseases
    Eeva Auvinen
    Department of Virology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 3, POB 21, 00014, Helsinki, Finland
    Mol Diagn Ther 21:45-57. 2017
    ..In this review the diagnostic possibilities offered by miRNA will be discussed. The focus will be on selected viral and human miRNAs in viral diseases, and examples of miRNAs of putative diagnostic potential will be presented...
  2. doi Altered expression of ezrin, E-Cadherin and β-Catenin in cervical neoplasia
    E Auvinen
    Department of Virology, University of Helsinki, Helsinki, Finland
    Neoplasma 60:56-61. 2013
    ..Further clinical evaluation should reveal the feasibility of ezrin as a biomarker for the progression of cervical lesions...
  3. ncbi Human papillomavirus 16 in a heart transplant recipient
    E Auvinen
    Department of Virology, Haartman Institute of Helsinki University Helsinki University Central Hospital, Helsinki, Finland
    Transplant Proc 34:1281-2. 2002
  4. ncbi Human papillomavirus type 16 E5 protein colocalizes with the antiapoptotic Bcl-2 protein
    E Auvinen
    Department of Virology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Arch Virol 149:1745-59. 2004
    ..Most interestingly, a remarkable colocalization of the E5 protein with the Bcl-2 antiapoptotic protein on intracellular membranes was established...
  5. ncbi High prevalence of HPV among female students in Finland
    Eeva Auvinen
    Department of Virology, HUSLAB Clinical Microbiology and Haartman Institute, University of Helsinki, Helsinki, Finland
    Scand J Infect Dis 37:873-6. 2005
    ..3% were positive for high-risk HPV. The study demonstrated a strikingly high HPV DNA prevalence among the young women. Self-collected samples proved to be acceptable for HPV DNA detection using liquid hybridization...
  6. ncbi Regulation of ezrin localization by Rac1 and PIPK in human epithelial cells
    Eeva Auvinen
    Department of Virology, Haartman Institute, University of Helsinki, and HUSLAB Clinical Microbiology, Helsinki University Central Hospital, Helsinki, Finland
    Exp Cell Res 313:824-33. 2007
    ..This localization required the activity of Rac1 and phosphatidylinositol-4-phosphate 5-kinase and involved RhoA. We suggest that localization of ezrin in adherens junctions is regulated by Rac in a manner involving PIPK...
  7. ncbi Repeated human papillomavirus DNA findings among female university students
    E Auvinen
    Department of Virology, HUSLAB Clinical Microbiology and Haartman Institute, University of Helsinki, Helsinki, Finland
    Int J STD AIDS 18:839-41. 2007
    ..hrHPV DNA was repeatedly found twice as often as lrHPV DNA. HPV DNA prevalence was higher among oral contraceptive users than among patients using other contraception...
  8. doi Simultaneous BK Polyomavirus (BKPyV)-associated nephropathy and hemorrhagic cystitis after living donor kidney transplantation
    Ilkka Helantera
    Transplantation and Liver Surgery, University of Helsinki and Helsinki University Hospital, PO Box 372, FI 00029HUS, Helsinki, Finland Electronic address
    J Clin Virol 76:4-7. 2016
    ..Symptoms of cystitis and viremia subsided rapidly after reduction of immunosuppression. ..
  9. doi BK virus viremia in a well-HLA-matched kidney transplant population mainly on low-dose cyclosporine-based immunosuppression
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Transplant 26:E596-601. 2012
    ..No grafts were lost due to PyVAN. Even in a low-risk population, BKV viremia and PyVAN occur, highlighting the importance of monitoring viral loads. Reduction of immunosuppression was successful, and no grafts were lost due to PyVAN...
  10. doi High-level JCPyV viruria after kidney transplantation-Clinical and histopathological findings
    Ilkka Helantera
    Transplantation and Liver Surgery, University of Helsinki and Helsinki University Hospital, PO Box 372, FI 00029 HUS, Helsinki, Finland Electronic address
    J Clin Virol 85:75-79. 2016
    ..The significance of JC polyomavirus (JCPyV) after kidney transplantation ranges from irrelevant to full-blown nephropathy or PML...
  11. pmc Detection of human papillomaviruses by polymerase chain reaction and ligation reaction on universal microarray
    Jarmo Ritari
    Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    PLoS ONE 7:e34211. 2012
    ..The preliminary results suggest that our test has accurate multiple HPV genotyping capability with the additional advantages of generic detection format, and potential for high-throughput screening...
  12. pmc Identification and validation of human papillomavirus encoded microRNAs
    Kui Qian
    Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    PLoS ONE 8:e70202. 2013
    ..To our knowledge, this is also the first paper to use in situ hybridization to show the expression of a viral microRNA in human tissue. ..
  13. doi Expression of toll-like receptors in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma--an in vivo and in vitro study
    Lauri Jouhi
    Department of Otorhinolaryngology Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4C 4E, P O Box 220, FI 00029, Helsinki, Finland
    Tumour Biol 36:7755-64. 2015
    ..Overall, TLR 7 and 9 expression patterns are demonstrated here to relate to the HPV status in vivo and TLR 5 and 7 expression patterns to the p16 status in vivo and in vitro...
  14. ncbi HPV DNA testing as an adjunct in the management of patients with low grade cytological lesions in Finland
    Jussi Tarkkanen
    Department of Pathology, Helsinki University Central Hospital, Finland
    Acta Obstet Gynecol Scand 86:367-72. 2007
    ..Patients with recurrent low grade cytological abnormalities are at increased risk for high grade lesions. We wanted to see whether these patients could be identified by HPV DNA and pap tests...
  15. doi BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: treatment response and evidence for nosocomial transmission
    Minna Koskenvuo
    Division of Hematology Oncology and Stem Cell Transplantation, Childrens Hospital and Helsinki University Central Hospital, Helsinki, Finland
    J Clin Virol 56:77-81. 2013
    ..BK-PyVHC typically presents with clinical cystitis, macrohematuria, and increasing urine and blood BKV loads...
  16. doi Transmission of human papillomavirus DNA from patient to surgical masks, gloves and oral mucosa of medical personnel during treatment of laryngeal papillomas and genital warts
    Taru Ilmarinen
    Department of Otorhinolaryngology, Head and Neck Surgery, Helsinki University Hospital, P O Box 220, 00029, Helsinki, Finland
    Eur Arch Otorhinolaryngol 269:2367-71. 2012
    ....
  17. pmc Low expression levels of putative HPV encoded microRNAs in cervical samples
    Elina Virtanen
    Department of Virology, University of Helsinki and Helsinki University Hospital, POB 21, 00014 Helsinki, Finland
    Springerplus 5:1856. 2016
    ..One liquid cytology sample from a patient with CIN3 as well as all four cell lines were positive for HPV16-miR-H3. In all cases HPV encoded microRNAs were expressed at low levels...
  18. doi Low expression of nuclear Toll-like receptor 4 in laryngeal papillomas transforming into squamous cell carcinoma
    Taru Ilmarinen
    Department of Otorhinolaryngology Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
    Otolaryngol Head Neck Surg 151:785-90. 2014
    ..The aim of this study was to determine the malignant transformation rate of laryngeal papillomas (LPs) and analyze the potential of TLR2, TLR4, and TLR9 immunoexpression as indicators of the increased cancer risk...
  19. doi miRSeqNovel: an R based workflow for analyzing miRNA sequencing data
    Kui Qian
    DNA sequencing and genomics laboratory, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    Mol Cell Probes 26:208-11. 2012
    ..It finds differentially expressed miRNAs and gives conservative prediction of novel miRNA candidates with customized parameters. miRSeqNovel is freely available at http://sourceforge.net/projects/mirseq/files...
  20. doi Expression of BKV and JCV encoded microRNA in human cerebrospinal fluid, plasma and urine
    Tuuli Pietilä
    Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland
    J Clin Virol 65:1-5. 2015
    ..BK and JC polyomaviruses encode microRNAs which may facilitate the establishment of persistent infection. MicroRNAs contribute to disease pathogenesis, and may provide useful tools in laboratory diagnostics and patient management...
  21. ncbi Prevalence and physical status of human papillomavirus in squamous cell carcinomas of the head and neck
    Walter J Koskinen
    Department of Virology, Haartman Institute, University of Helsinki and HUCH Laboratory Diagnostics, Helsinki, Finland
    Int J Cancer 107:401-6. 2003
    ..Patients with episomal viral DNA were more frequently found to have large (T3-T4) tumors at diagnosis than were those with integrated or mixed forms...
  22. doi Cervical nitric oxide release in Chlamydia trachomatis and high-risk human papillomavirus infection
    Paivi Rahkola
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Acta Obstet Gynecol Scand 90:961-5. 2011
    ..To compare cervical fluid nitric oxide release in women with and without Chlamydia trachomatis and high-risk human papillomavirus infection (hrHPV)...
  23. pmc Human papillomavirus 16 E5 modulates the expression of host microRNAs
    Dario Greco
    DNA sequencing and genomics laboratory, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    PLoS ONE 6:e21646. 2011
    ..Our results indicate that HPV infection and subsequent transformation take place through complex regulatory patterns of gene expression in the host cells, part of which are regulated by the E5 protein...
  24. doi Performance of mRNA- and DNA-based high-risk human papillomavirus assays in detection of high-grade cervical lesions
    Elina Virtanen
    Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    Acta Obstet Gynecol Scand 96:61-68. 2017
    ..Test performance was compared in the settings of a standard colposcopy clinic, among the regular patient flow...
  25. doi Performance of the Luminex xTAG Respiratory Viral Panel Fast in a clinical laboratory setting
    Pia Jokela
    Department of Virology, Haartman Institute, University of Helsinki, FIN 00014 Helsinki, Finland
    J Virol Methods 182:82-6. 2012
    ..004) by RVP in comparison to real-time RT-PCR was observed. The results of the present study imply the need to adjust the InfA component of the RVP Fast assay to also cover the InfA(H1N1) 2009 virus...
  26. doi Polyomavirus BK and JC infections in well matched Finnish kidney transplant recipients
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Central Hospital and University of Helsinki, FIN 00029 HUS, Helsinki, Finland
    Transpl Int 22:688-93. 2009
    ..The incidence of BK and JC viruria was similar to what has been previously reported, but no cases of polyomavirus-associated nephropathy were seen in our well-matched kidney transplant population...