J Paavonen

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi request reprint Interactions between human papillomavirus and other sexually transmitted agents in the etiology of cervical cancer
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Curr Opin Infect Dis 12:67-71. 1999
  2. ncbi request reprint Chlamydia trachomatis: impact on human reproduction
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Hum Reprod Update 5:433-47. 1999
  3. ncbi request reprint Serotypes of Chlamydia trachomatis and risk for development of cervical squamous cell carcinoma
    T Anttila
    Department of Obstetrics and Gynecology, University of Helsinki, Haartmaninkatu 2, 00290 Helsinki, Finland
    JAMA 285:47-51. 2001
  4. ncbi request reprint Chlamydia trachomatis and chlamydial heat shock protein 60-specific antibody and cell-mediated responses predict tubal factor infertility
    A Tiitinen
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland
    Hum Reprod 21:1533-8. 2006
  5. doi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on cardiovascular disease risk factors in menorrhagia patients: a 10-year follow-up of a randomised trial
    S Heliövaara-Peippo
    Department of Obstetrics and Gynaecology, Helsinki University Hospital, Helsinki, Finland
    Maturitas 69:354-8. 2011
  6. doi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on lower urinary tract symptoms: a 10-year follow-up study of a randomised trial
    S Heliövaara-Peippo
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland
    BJOG 117:602-9. 2010
  7. ncbi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on sexual functioning among women with menorrhagia: a 5-year randomised controlled trial
    K Halmesmäki
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    BJOG 114:563-8. 2007
  8. ncbi request reprint Vaginal clindamycin in preventing preterm birth and peripartal infections in asymptomatic women with bacterial vaginosis: a randomized, controlled trial
    M Kekki
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland
    Obstet Gynecol 97:643-8. 2001
  9. ncbi request reprint Human papillomavirus infection, risk for subsequent development of cervical neoplasia and associated population attributable fraction
    M Lehtinen
    National Public Health, Institute, FIN 00300, Helsinki, Finland
    J Clin Virol 22:117-24. 2001
  10. doi request reprint Elevated levels of decidual insulin-like growth factor binding protein-1 in cervical fluid in early and mid-pregnancy are associated with an increased risk of spontaneous preterm delivery
    L Rahkonen
    Department of Obstetrics and Gynaecology, Helsinki University Hospital, Helsinki, Finland
    BJOG 117:701-10. 2010

Detail Information

Publications48

  1. ncbi request reprint Interactions between human papillomavirus and other sexually transmitted agents in the etiology of cervical cancer
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Curr Opin Infect Dis 12:67-71. 1999
    ..trachomatis, as well as between the different human papillomavirus types...
  2. ncbi request reprint Chlamydia trachomatis: impact on human reproduction
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Hum Reprod Update 5:433-47. 1999
    ..Thus, the case for screening is clearly made, but much detail remains to be worked out...
  3. ncbi request reprint Serotypes of Chlamydia trachomatis and risk for development of cervical squamous cell carcinoma
    T Anttila
    Department of Obstetrics and Gynecology, University of Helsinki, Haartmaninkatu 2, 00290 Helsinki, Finland
    JAMA 285:47-51. 2001
    ..Increasing numbers of exposures to different C trachomatis serotypes also increases risk. Our results strengthen the evidence that there is a link between past C trachomatis infection and cervical SCC...
  4. ncbi request reprint Chlamydia trachomatis and chlamydial heat shock protein 60-specific antibody and cell-mediated responses predict tubal factor infertility
    A Tiitinen
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland
    Hum Reprod 21:1533-8. 2006
    ..To evaluate the role of Chlamydia trachomatis-induced humoral and cell-mediated immune (CMI) responses in predicting tubal factor infertility (TFI)...
  5. doi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on cardiovascular disease risk factors in menorrhagia patients: a 10-year follow-up of a randomised trial
    S Heliövaara-Peippo
    Department of Obstetrics and Gynaecology, Helsinki University Hospital, Helsinki, Finland
    Maturitas 69:354-8. 2011
    ..To compare, whether women with menorrhagia, treated with either hysterectomy or LNG-IUS, differ in their cardiovascular risk profile during 10-year follow-up...
  6. doi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on lower urinary tract symptoms: a 10-year follow-up study of a randomised trial
    S Heliövaara-Peippo
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland
    BJOG 117:602-9. 2010
    ..To evaluate the effect of hysterectomy and levonorgestrel-releasing intrauterine system (LNG-IUS) on lower urinary tract symptoms (LUTS) among women treated for menorrhagia...
  7. ncbi request reprint The effect of hysterectomy or levonorgestrel-releasing intrauterine system on sexual functioning among women with menorrhagia: a 5-year randomised controlled trial
    K Halmesmäki
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    BJOG 114:563-8. 2007
    ..To compare among women with menorrhagia the effect of hysterectomy or levonorgestrel-releasing intrauterine system (LNG-IUS) on sexual functioning...
  8. ncbi request reprint Vaginal clindamycin in preventing preterm birth and peripartal infections in asymptomatic women with bacterial vaginosis: a randomized, controlled trial
    M Kekki
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland
    Obstet Gynecol 97:643-8. 2001
    ..To determine whether treatment of bacterial vaginosis (BV) in early pregnancy decreases the risk of preterm delivery and peripartum infectious morbidity...
  9. ncbi request reprint Human papillomavirus infection, risk for subsequent development of cervical neoplasia and associated population attributable fraction
    M Lehtinen
    National Public Health, Institute, FIN 00300, Helsinki, Finland
    J Clin Virol 22:117-24. 2001
    ..PAR% has not been derived from longitudinal studies although assessment of HPV exposure prior to the neoplasia diagnosis should increase validity of such estimates...
  10. doi request reprint Elevated levels of decidual insulin-like growth factor binding protein-1 in cervical fluid in early and mid-pregnancy are associated with an increased risk of spontaneous preterm delivery
    L Rahkonen
    Department of Obstetrics and Gynaecology, Helsinki University Hospital, Helsinki, Finland
    BJOG 117:701-10. 2010
    ..To study whether elevated levels of decidual insulin-like growth factor binding protein-1 (IGFBP-1) in the cervical fluid of unselected asymptomatic women in early or mid-pregnancy are associated with spontaneous preterm delivery (PTD)...
  11. ncbi request reprint Poor antibody response against human papillomavirus in adult-onset laryngeal papillomatosis
    L M Aaltonen
    Department of Virology, Haartman Institute, University of Helsinki, Helsinki University Central Hospital, Finland
    J Med Microbiol 50:468-71. 2001
    ..The high prevalence of abnormal Pap smears indicates that gynaecological examination of female adult-onset laryngeal papilloma patients is warranted...
  12. ncbi request reprint Pelvic inflammatory disease. From diagnosis to prevention
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Dermatol Clin 16:747-56, xii. 1998
    ..Emerging evidence from randomized controlled trials provides strong evidence that intervention with selective screening for chlamydial infection effectively reduces the incidence of PID...
  13. ncbi request reprint Psychosocial and other characteristics of women complaining of menorrhagia, with and without actual increased menstrual blood loss
    R Hurskainen
    Department of Obstetrics and Gynaecology, University of Helsinki, Finland
    BJOG 108:281-5. 2001
    ..Better understanding of the factors, which explain complaints of menorrhagia in women with normal bleeding could improve both medical outcomes and reduce the cost of treatment for menorrhagia...
  14. ncbi request reprint Insulin-like growth factor-binding protein-1 in cervical secretion as a predictor of preterm delivery
    M Kekki
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, and Medix Biochemica, Kauniainen, Finland
    Acta Obstet Gynecol Scand 80:546-51. 2001
    ..CONCLUSIONS: Pregnant women who are in preterm labor with intact fetal membranes and who have a positive phIGFBP-1 test result in cervical secretion have an increased risk of preterm delivery...
  15. doi request reprint Prediction of placental abruption by testing for C-reactive protein and chlamydial antibody levels in early pregnancy
    M Tikkanen
    Department of Obstetrics and Gynaecology, University Central Hospital, Helsinki, Finland
    BJOG 115:486-91. 2008
    ..We wanted to assess the association of first-trimester serum C-reactive protein (CRP), Chlamydia pneumoniae antibodies, Chlamydia trachomatis antibodies or chlamydial heat-shock protein 60 (CHSP60) antibodies to placental abruption...
  16. ncbi request reprint Population-based enrolment of adolescents in a long-term follow-up trial of human papillomavirus vaccine efficacy
    M Lehtinen
    University of Tampere, Helsinki, Finland
    Int J STD AIDS 17:237-46. 2006
    ..Population-based enrollment of large cohorts of vaccinated and unvaccinated adolescents for passive registry-based follow-up with cervical carcinoma as the end-point is feasible and currently going on in Finland...
  17. pmc Comparison of performances of two commercially available tests, a PCR assay and a ligase chain reaction test, in detection of urogenital Chlamydia trachomatis infection
    M Puolakkainen
    Haartman Institute, Department of Virology, University of Helsinki, Finland
    J Clin Microbiol 36:1489-93. 1998
    ..trachomatis infection. In conclusion, both tests can be recommended for use in the clinical laboratory and for the screening of asymptomatic C. trachomatis infections...
  18. ncbi request reprint Human papillomavirus infection and primary fallopian tube carcinoma: a seroepidemiological study
    A Riska
    Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland
    BJOG 114:425-9. 2007
    ..To evaluate the role of human papillomavirus (HPV) types 6, 11, 16, 18, 31 or 33 infection in primary fallopian tube carcinoma (PFTC)...
  19. doi request reprint Long-term mortality in women treated for cervical intraepithelial neoplasia
    M Jakobsson
    Department of Obstetrics and Gynaecology, University Hospital, Helsinki, Finland
    BJOG 116:838-44. 2009
    ..We also wanted to study whether pregnancy beyond 22 weeks post-treatment affects the risk...
  20. ncbi request reprint Prerequisites for human papillomavirus vaccine trial: results of feasibility studies
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Haartmaninkatu 2, 00290, Helsinki, Finland
    J Clin Virol 19:25-30. 2000
    ..First generation preventive vaccines against HPVs are entering clinical trials. Therefore, it is time to consider prerequisites of field trials in Finland...
  21. ncbi request reprint Chlamydial pelvic inflammatory disease
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Hum Reprod Update 2:519-29. 1996
    ..The development and implementation of new and effective intervention programmes for prevention and control of PID is one of the major challenges for the year 2000 and beyond...
  22. doi request reprint Factors affecting decidual IGFBP-1 levels in the vagina and cervix in the first and mid-second trimester of pregnancy
    L Rahkonen
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland
    BJOG 116:45-54. 2009
    ..The aim of this study was to determine the concentrations of and factors associated with decidual insulin-like growth factor-binding protein-1 (IGFBP-1) in the lower genital tract in early- and mid-gestation in singleton pregnancies...
  23. doi request reprint Amniotic fluid rapid biomarkers are associated with intra-amniotic infection in preterm pregnancies regardless of the membrane status
    T Myntti
    Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    J Perinatol 36:606-11. 2016
    ....
  24. ncbi request reprint Expression of sex steroid receptors and Ki-67 in the endometria of menorrhagic women: effects of intrauterine levonorgestrel
    R Hurskainen
    Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, PO Box 140, Helsinki, Finland
    Mol Hum Reprod 6:1013-8. 2000
    ..No significant differences were found in the parameters studied between the women with and without breakthrough bleeding 6 months after insertion of an LNG-IUS...
  25. ncbi request reprint Heat shock protein 60 specific T-cell response in chlamydial infections
    A Kinnunen
    Department of Obstetrics and Gynaecology, University of Helsinki, Helsinki and National Public Health Institute, Oulu, Finland
    Scand J Immunol 54:76-81. 2001
    ..Our review highlights the available knowledge between immune responses to chlamydial HSP60 and chronic chlamydial infections in human...
  26. ncbi request reprint Repeated human papillomavirus DNA findings among female university students
    E Auvinen
    Department of Virology, HUSLAB Clinical Microbiology and Haartman Institute, University of Helsinki, Helsinki, Finland
    Int J STD AIDS 18:839-41. 2007
    ..hrHPV DNA was repeatedly found twice as often as lrHPV DNA. HPV DNA prevalence was higher among oral contraceptive users than among patients using other contraception...
  27. ncbi request reprint The use of serologic tests for the diagnosis of chlamydial infections
    T Tuuminen
    Labsystems Research Laboratories, Labsystems OY, Sorvaajankatu 15, 00811, Helsinki, Finland
    J Microbiol Methods 42:265-79. 2000
    ....
  28. pmc Enhanced tenascin expression in cervical and vulvar koilocytotic lesions
    O Tiitta
    Department of Anatomy, University of Helsinki, Finland
    Am J Pathol 141:907-13. 1992
    ..Enhancement was most consistently strong and extensive in in situ carcinomas, suggesting a correlation with active phases of epithelial growth and stromal remodeling...
  29. pmc A population-based study on the risk of cervical cancer and cervical intraepithelial neoplasia among grand multiparous women in Finland
    M Hinkula
    Department of Obstetrics and Gynecology, University of Oulu, PL 24, FIN 90029 OYS, Finland
    Br J Cancer 90:1025-9. 2004
    ..2 and 1.4 should be interpreted to represent increased risk attributable to grand multiparity. The increased incidence of CC and CIN3 among young GM women suggests causal association to HPV 16 and Chlamydia trachomatis infections...
  30. ncbi request reprint Vaginal clindamycin and oral metronidazole for bacterial vaginosis: a randomized trial
    J Paavonen
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Obstet Gynecol 96:256-60. 2000
    ..To compare the efficacy and safety of clindamycin vaginal ovules with oral metronidazole for treatment of bacterial vaginosis...
  31. ncbi request reprint Efficacy of preventive human papillomavirus vaccination
    M Lehtinen
    National Public Health Institute and the Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Int J STD AIDS 12:771-6. 2001
    ..The present review attempts to answer one fundamental question: which of the vaccine candidates is likely to be most successful...
  32. doi request reprint Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women
    J Paavonen
    Department of Obstetrics and Gynaecology, University of Helsinki, Helsinki, Finland
    Lancet 374:301-14. 2009
    ..We now assess the vaccine efficacy in the final event-driven analysis...
  33. pmc Chlamydia trachomatis heat shock protein-60 induced interferon-gamma and interleukin-10 production in infertile women
    A Kinnunen
    National Public Health Institute, Oulu, Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Clin Exp Immunol 131:299-303. 2003
    ....
  34. doi request reprint Comparison of amniotic fluid matrix metalloproteinase-8 and cathelicidin in the diagnosis of intra-amniotic infection
    T Myntti
    Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    J Perinatol 36:1049-1054. 2016
    ....
  35. ncbi request reprint Cost-benefit analysis of first-void urine Chlamydia trachomatis screening program
    J Paavonen
    Department of Obstetrics and Gynecology and the Haartman Institute, University of Helsinki, Finland
    Obstet Gynecol 92:292-8. 1998
    ..To perform a cost-benefit analysis of a Chlamydia trachomatis screening program based on first-void urine testing of asymptomatic women using a polymerase chain reaction (PCR) test...
  36. ncbi request reprint Portfolios as a learning tool in obstetrics and gynaecology undergraduate training
    K Lonka
    Development and Research Unit, Faculty of Medicine, University of Helsinki, Finland
    Med Educ 35:1125-30. 2001
    ..The main objective was to support the learning process of the students. We also wanted feedback information to enhance teaching...
  37. ncbi request reprint The incidence of preterm deliveries decreases in Finland
    M Jakobsson
    Department of Obstetrics and Gynaecology, University Hospital, Helsinki, Finland
    BJOG 115:38-43. 2008
    ..We examined the trends and risk factors of preterm delivery...
  38. ncbi request reprint Sexually transmitted diseases. Lower genital tract infections in women
    J Paavonen
    Department of Obstetrics and Gynecology, University Central Hospital, Helsinki, Finland
    Infect Dis Clin North Am 1:179-98. 1987
    ..Recent studies have considerably improved our understanding of the etiology, pathophysiology, diagnosis, and treatment of these infections...
  39. doi request reprint Baseline demographic characteristics of subjects enrolled in international quadrivalent HPV (types 6/11/16/18) vaccine clinical trials
    Jorma Paavonen
    Department of Obstetrics and Gynecology, University Hospital, Helsinki, Finland
    Curr Med Res Opin 24:1623-34. 2008
    ..However, the makeup and extent of catch-up vaccination programs among young women is unclear, because a proportion of this population will likely already have been exposed to one or more vaccine-HPV-types...
  40. pmc Evaluation of the Oricult-N dipslide for laboratory diagnosis of vaginal candidiasis
    P Carlson
    Division of Bacteriology, HUCH Diagnostics, Haartman Institute, University of Helsinki, Helsinki, Finland
    J Clin Microbiol 38:1063-5. 2000
    ..The Oricult-N method was technically simple and could be applied in primary health care. Further studies are required, however, before Oricult-N can be recommended as a routine diagnostic tool...
  41. doi request reprint Long-term neurodevelopmental outcome of children from euploid pregnancies with increased nuchal translucency in the first trimester screening
    O Ayräs
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland
    Prenat Diagn 35:362-9. 2015
    ....
  42. doi request reprint Foley catheter induction of labor as an outpatient procedure
    H Kruit
    Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    J Perinatol 36:618-22. 2016
    ..The aim of our study was to introduce outpatient induction of labor by Foley catheter, and to compare outcomes and preferences between in-patients and outpatients...
  43. ncbi request reprint Antibody to Chlamydia trachomatis proteins, TroA and HtrA, as a biomarker for Chlamydia trachomatis infection
    K Hokynar
    Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    Eur J Clin Microbiol Infect Dis . 2016
    ..We studied whether antibody to two chlamydial proteins (TroA and HtrA) could be used as biomarkers of Chlamydia trachomatis infection...
  44. ncbi request reprint Wound complications in patients with carcinoma of the vulva. Comparison between radical and modified vulvectomies
    A Leminen
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland
    Eur J Obstet Gynecol Reprod Biol 93:193-7. 2000
    ..To evaluate complications after different vulvectomies performed because of vulvar cancer...
  45. ncbi request reprint A randomized controlled trial of hysterectomy or levonorgestrel-releasing intrauterine system in the treatment of menorrhagia-effect on FSH levels and menopausal symptoms
    K Halmesmäki
    Department of Obstetrics and Gynecology, Central Hospital of Päijät Häme, Keskussairaalankatu 7, 15850 Lahti, Finland
    Hum Reprod 19:378-82. 2004
    ..The purpose of this study was to compare the effects of hysterectomy and a levonorgestrel-releasing intrauterine system (LNG-IUS) on serum FSH levels and menopausal symptoms...
  46. ncbi request reprint Effectiveness of preventive human papillomavirus vaccination
    M Lehtinen
    National Public Health Institute and the Department of Obstetrics and Gynaecology, University of Helsinki, Helsinki, Finland
    Int J STD AIDS 14:787-92. 2003
    ....
  47. ncbi request reprint Transvaginal power Doppler findings in laparoscopically proven acute pelvic inflammatory disease
    P Molander
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Ultrasound Obstet Gynecol 17:233-8. 2001
    ..Specific sonographic landmark findings and power Doppler findings augment the clinical diagnosis of PID and allow simple classification of the severity of the disease...
  48. ncbi request reprint Transvaginal sonography in the diagnosis of acute appendicitis
    P Molander
    Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland
    Ultrasound Obstet Gynecol 20:496-501. 2002
    ..To evaluate transvaginal sonography with power Doppler capacity in the diagnosis of acute appendicitis and in discriminating appendicitis from pelvic inflammatory disease...