Weiwei Feng

Summary

Publications

  1. pmc Leukemoid reaction in cervical cancer: a case report and review of the literature
    Li Qing
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shen Yang Road 128, Shanghai, China
    BMC Cancer 14:670. 2014
  2. doi request reprint Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Histopathology 62:688-94. 2013
  3. doi request reprint Prognostic indicators in WHO 2003 low-grade endometrial stromal sarcoma
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Histopathology 62:675-87. 2013
  4. pmc Correlation between CpG methylation profiles and hormone receptor status in breast cancers
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 9:R57. 2007
  5. doi request reprint Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 112:1489-502. 2008
  6. pmc Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome
    Jia Xu
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    BMC Cancer 12:243. 2012
  7. pmc Can proliferation biomarkers reliably predict recurrence in World Health Organization 2003 defined endometrial stromal sarcoma, low grade?
    Weiwei Feng
    Department of Gynecology and Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    PLoS ONE 8:e75899. 2013
  8. doi request reprint Prognostic value of the diagnostic criteria distinguishing endometrial stromal sarcoma, low grade from undifferentiated endometrial sarcoma, 2 entities within the invasive endometrial stromal neoplasia family
    Weiwei Feng
    Department of Gynecology and Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    Int J Gynecol Pathol 32:299-306. 2013
  9. doi request reprint Stages I to II WHO 2003-defined low-grade endometrial stromal sarcoma: how much primary therapy is needed and how little is enough?
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Int J Gynecol Cancer 23:488-93. 2013
  10. doi request reprint Estrogen stimulates the invasion of ovarian cancer cells via activation of the PI3K/AKT pathway and regulation of its downstream targets E‑cadherin and α‑actinin‑4
    Zhiying Lu
    Department of Gynecology, The Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, P R China
    Mol Med Rep 10:2433-40. 2014

Collaborators

Detail Information

Publications21

  1. pmc Leukemoid reaction in cervical cancer: a case report and review of the literature
    Li Qing
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shen Yang Road 128, Shanghai, China
    BMC Cancer 14:670. 2014
    ..Two cervical cancers presenting with leukemoid reactions were previously reported. However, the cancers in these cases were mainly in the advanced stages and had a poor outcome...
  2. doi request reprint Diagnostic and prognostic morphometric features in WHO2003 invasive endometrial stromal tumours
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Histopathology 62:688-94. 2013
    ....
  3. doi request reprint Prognostic indicators in WHO 2003 low-grade endometrial stromal sarcoma
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Histopathology 62:675-87. 2013
    ..Since 2003, many studies have used the old criteria, and few have focused on WHO 2003-defined ESS low grade (ESS-LG). The aim of this study was to investigate prognosticators in ESS-LG...
  4. pmc Correlation between CpG methylation profiles and hormone receptor status in breast cancers
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 9:R57. 2007
    ..The present study was undertaken to determine whether methylation of a set of growth-suppressor genes would correlate to the expression of estrogen receptors (ERs) and progesterone receptors (PRs)...
  5. doi request reprint Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 112:1489-502. 2008
    ..Two imprinted genes, paternally expressed 3 (PEG3) and aplasia Ras homologue member I (ARHI), are the most frequently down-regulated in ovarian cancers on gene expression arrays...
  6. pmc Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome
    Jia Xu
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    BMC Cancer 12:243. 2012
    ..To determine the impact of methylation on clinical outcome, we have conducted a larger study with breast cancers for which time to first recurrence and overall survival are known...
  7. pmc Can proliferation biomarkers reliably predict recurrence in World Health Organization 2003 defined endometrial stromal sarcoma, low grade?
    Weiwei Feng
    Department of Gynecology and Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    PLoS ONE 8:e75899. 2013
    ..In conclusion, in this small study of WHO2003 defined ESS-LG, high levels of proliferation as measured by MAI, PPH3 and Ki-67 are predictive of recurrence. Larger studies are required to confirm these results...
  8. doi request reprint Prognostic value of the diagnostic criteria distinguishing endometrial stromal sarcoma, low grade from undifferentiated endometrial sarcoma, 2 entities within the invasive endometrial stromal neoplasia family
    Weiwei Feng
    Department of Gynecology and Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    Int J Gynecol Pathol 32:299-306. 2013
    ..00001, hazard ratio=45.4). When strictly defined microscopic criteria are used, the WHO 2003 diagnoses of ESS, low grade and UES are well reproducible and prognostically strong...
  9. doi request reprint Stages I to II WHO 2003-defined low-grade endometrial stromal sarcoma: how much primary therapy is needed and how little is enough?
    Weiwei Feng
    Department of Gynaecology, Hospital of Fudan University, Shanghai, China
    Int J Gynecol Cancer 23:488-93. 2013
    ..However, primary treatment practices range from limited surgery only to extensive surgery combined with adjuvant chemotherapy and radiotherapy. We focused on the primary treatment of early-stage WHO 2003-defined low-grade ESS...
  10. doi request reprint Estrogen stimulates the invasion of ovarian cancer cells via activation of the PI3K/AKT pathway and regulation of its downstream targets E‑cadherin and α‑actinin‑4
    Zhiying Lu
    Department of Gynecology, The Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, P R China
    Mol Med Rep 10:2433-40. 2014
    ..Inhibiting the PI3K/AKT pathway may be a useful treatment for ovarian carcinoma. ..
  11. ncbi request reprint Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 120:1664-8. 2007
    ..Since HDAC inhibitors are now being used to treat breast cancer, the reactivation of ARHI in these cancer cells may serve as a new biomarker with which to monitor the treatment effects...
  12. ncbi request reprint Prognostic value of the diagnostic criteria distinguishing endometrial stromal sarcoma, low grade from undifferentiated endometrial sarcoma, 2 entities within the invasive endometrial stromal neoplasia family
    Weiwei Feng
    Department of Gynecology and Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    Int J Gynecol Pathol 31:151-8. 2012
    ..00001, hazard ratio=45.4). When strictly defined microscopic criteria are used, the WHO 2003 diagnoses of ESS, low grade and UES are well reproducible and prognostically strong...
  13. doi request reprint Effects of oestrogen on long noncoding RNA expression in oestrogen receptor alpha-positive ovarian cancer cells
    Junjun Qiu
    Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China Department of Obstetrics and Gynecology of Shanghai Medical College, Fudan University, China Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China
    J Steroid Biochem Mol Biol 141:60-70. 2014
    ..Furthermore, our findings reveal that TC0101441contributes to E2-induced EOC cell migration/invasion. These results may shed a new insight into estrogenic effect on EOC progression by providing a perspective of lncRNA. ..
  14. pmc Enhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinoma
    Nan Jia
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200090, P R China Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200090, P R China
    Oncol Lett 8:2049-2054. 2014
    ..Therefore, these findings indicate that EZH2 expression may predict a more aggressive biological behavior in endometrial carcinoma and it may provide potential therapeutic targets for treatment of endometrial carcinoma...
  15. ncbi request reprint Clinicopathological risk factors for pelvic lymph node metastasis in clinical early-stage endometrioid endometrial adenocarcinoma
    Chuyao Zhang
    Department of Gynecology, Obstetrics and Gynaecology Hospital, Fudan University, Shanghai, China
    Int J Gynecol Cancer 22:1373-7. 2012
    ..To identify the clinicopathological risk factors for pelvic lymph node (PLN) metastasis and to evaluate the predictive significance of these factors for lymphadenectomy in clinical early-stage endometrioid endometrial adenocarcinoma (EEA)...
  16. doi request reprint Uterine carcinosarcoma and high-risk endometrial carcinomas: a clinicopathological comparison
    Chuyao Zhang
    Department of Gynecology, Obstetrics and Gynecology Hospital, Shanghai Key Laboratory of Female Reproductive Endocrine Related Disease, and Department of Pathology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
    Int J Gynecol Cancer 25:629-36. 2015
    ....
  17. doi request reprint Cost-benefit analysis of laparoscopic surgery versus laparotomy for patients with endometrioid endometrial cancer: experience from an institute in China
    Zhiying Lu
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, 419 Fang Xie Road, Shanghai, China
    J Obstet Gynaecol Res 38:1011-7. 2012
    ..To compare the clinical outcomes and associated costs between laparoscopic and abdominal surgery for patients with endometrioid endometrial cancer...
  18. pmc Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway
    Xiaohui Yan
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
    PLoS ONE 8:e63731. 2013
    ..Finally, Huaier inhibited the growth of ovarian tumor xenografts in vivo. These studies indicate that Huaier inhibits tumor cell mobility in ovarian cancer via the AKT/GSK3β/β-catenin signaling pathway...
  19. pmc Role of Numb expression and nuclear translocation in endometrial cancer
    Chao Wang
    Department of Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, P R China Department of Obstetrics and Gynecology, West China Second Hospital, Sichuan University, Chengdu, Sichuan, P R China
    Oncol Lett 9:1531-1536. 2015
    ..The role of Numb in cancer development requires additional investigation...
  20. pmc Factors that influence persistence or recurrence of high-grade squamous intraepithelial lesion with positive margins after the loop electrosurgical excision procedure: a retrospective study
    Menghan Zhu
    Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shen Yang Road 128, Shanghai, 200090, China
    BMC Cancer 15:744. 2015
    ....
  21. pmc Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers
    Weiwei Feng
    Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
    BMC Cancer 10:378. 2010
    ..This study is to investigate the status and role of methylation in lymph node metastatic tumors...