Ahmad M Farag

Summary

Publications

  1. ncbi request reprint Regioselective synthesis and antitumor screening of some novel N-phenylpyrazole derivatives
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:881-9. 2008
  2. doi request reprint Synthesis of new N-phenylpyrazole derivatives with potent antimicrobial activity
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:4569-78. 2008
  3. doi request reprint Synthesis and structure-activity relationship studies of pyrazole-based heterocycles as antitumor agents
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt
    Arch Pharm (Weinheim) 343:384-96. 2010
  4. doi request reprint Design, synthesis and structure-activity relationship study of novel pyrazole-based heterocycles as potential antitumor agents
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Eur J Med Chem 45:5887-98. 2010
  5. doi request reprint Recent advances in the therapeutic applications of pyrazolines
    Mohamed R Shaaban
    Cairo University, Faculty of Science, Department of Chemistry, Giza 12613, Egypt
    Expert Opin Ther Pat 22:253-91. 2012
  6. doi request reprint Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties
    Adel S Girgis
    Pesticide Chemistry Department, National Research Centre, El Behoos Street, Dokki, 12622 Cairo, Egypt
    Eur J Med Chem 43:1818-27. 2008
  7. ncbi request reprint Novel Benzo[d]imidazole-based Heterocycles as Broad Spectrum Anti-viral Agents: Design, Synthesis and Exploration of Molecular Basis of Action
    Taha M A Eldebss
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Mini Rev Med Chem 16:67-83. 2016
  8. doi request reprint Regioselective synthesis and ab initio calculations of fused heterocycles thermally and under microwave irradiation
    Mostafa E Salem
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Spectrochim Acta A Mol Biomol Spectrosc 148:175-83. 2015
  9. doi request reprint Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety
    Mohamed R Shaaban
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:6344-52. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Regioselective synthesis and antitumor screening of some novel N-phenylpyrazole derivatives
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:881-9. 2008
    ..The preliminary screening for the antitumor activity of all newly synthesized compounds was carried out against Ehrlich Ascites Carcinoma tumor cells...
  2. doi request reprint Synthesis of new N-phenylpyrazole derivatives with potent antimicrobial activity
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:4569-78. 2008
    ..From structure-activity relationship (SAR) point of view, the attachment of bromoacetyl moiety to pyrazole ring can be considered as a breakthrough in developing a new therapeutic antifungal agent related to phenylpyrazole system...
  3. doi request reprint Synthesis and structure-activity relationship studies of pyrazole-based heterocycles as antitumor agents
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt
    Arch Pharm (Weinheim) 343:384-96. 2010
    ..The oral LD(50) values revealed that most of the tested compounds are relatively nontoxic...
  4. doi request reprint Design, synthesis and structure-activity relationship study of novel pyrazole-based heterocycles as potential antitumor agents
    Ahmad M Farag
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Eur J Med Chem 45:5887-98. 2010
    ....
  5. doi request reprint Recent advances in the therapeutic applications of pyrazolines
    Mohamed R Shaaban
    Cairo University, Faculty of Science, Department of Chemistry, Giza 12613, Egypt
    Expert Opin Ther Pat 22:253-91. 2012
    ..Various methods have been worked out for their synthesis. Several pyrazoline derivatives have been found to possess diverse biological properties, which has stimulated research activity in this field...
  6. doi request reprint Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties
    Adel S Girgis
    Pesticide Chemistry Department, National Research Centre, El Behoos Street, Dokki, 12622 Cairo, Egypt
    Eur J Med Chem 43:1818-27. 2008
    ..Compounds 5b, 5c, 6b and 8g reveal remarkable vasodilation potency (IC50, concentrations necessary for 50% reduction of maximal norepinephrine hydrochloride induced contracture) 0.175, 0.146, 0.229 and 0.233 mM, respectively...
  7. ncbi request reprint Novel Benzo[d]imidazole-based Heterocycles as Broad Spectrum Anti-viral Agents: Design, Synthesis and Exploration of Molecular Basis of Action
    Taha M A Eldebss
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Mini Rev Med Chem 16:67-83. 2016
    ..Overall findings of the executed investigations highlight these novel compounds as very promising potent, broad spectrum antiviral agents...
  8. doi request reprint Regioselective synthesis and ab initio calculations of fused heterocycles thermally and under microwave irradiation
    Mostafa E Salem
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Spectrochim Acta A Mol Biomol Spectrosc 148:175-83. 2015
    ..It was found that the final cyclocondensation reaction product depends mainly on the initial addition to the activated double bond by the nitrogen atom of the 1,3-binucleophiles that has the higher electron density. ..
  9. doi request reprint Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety
    Mohamed R Shaaban
    Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
    Bioorg Med Chem 16:6344-52. 2008
    ....