Yue Fang

Summary

Publications

  1. pmc Vitamin D binding protein genotype and osteoporosis
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Center, Genetic Laboratory, Rotterdam, The Netherlands
    Calcif Tissue Int 85:85-93. 2009
  2. ncbi request reprint Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms
    Stephanie C E Schuit
    Department of Internal Medicine, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
    J Clin Endocrinol Metab 89:303-9. 2004
  3. ncbi request reprint Vitamin D receptor gene haplotype is associated with body height and bone size
    Yue Fang
    Genetic Laboratory, Room Ee575, Department of Internal Medicine, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:1491-501. 2007
  4. pmc Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Am J Hum Genet 77:807-23. 2005
  5. pmc Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
    Andre G Uitterlinden
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Hum Genet 75:1032-45. 2004
  6. ncbi request reprint Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Bone Miner Res 18:1632-41. 2003
  7. ncbi request reprint Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women
    Arjan P Bergink
    Erasmus University Medical Center, Rotterdam, The Netherlands
    Arthritis Rheum 48:1913-22. 2003
  8. ncbi request reprint Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: a meta-analysis
    Yue Fang
    Department of Internal Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands
    Bone 39:938-45. 2006
  9. ncbi request reprint Genetics and biology of vitamin D receptor polymorphisms
    Andre G Uitterlinden
    Genetic Laboratory, Room Ee575, Department of Internal Medicine, Erasmus MC, Dr Molewaterplein 50, PO Box 1738, NL 3000 DR Rotterdam, The Netherlands
    Gene 338:143-56. 2004
  10. ncbi request reprint The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis
    Andre G Uitterlinden
    Erasmus MC, Rotterdam, The Netherlands
    Ann Intern Med 145:255-64. 2006

Collaborators

Detail Information

Publications14

  1. pmc Vitamin D binding protein genotype and osteoporosis
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Center, Genetic Laboratory, Rotterdam, The Netherlands
    Calcif Tissue Int 85:85-93. 2009
    ..05). All associations were independent of age and gender. Our study demonstrated that the genetic effect of the DBP gene on fracture risk appears only in combination with other genetic and environmental risk factors for bone metabolism...
  2. ncbi request reprint Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms
    Stephanie C E Schuit
    Department of Internal Medicine, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
    J Clin Endocrinol Metab 89:303-9. 2004
    ..5 cm shorter per allele copy of the ESR1 haplotype 1 (P for trend = 0.03). In conclusion, we demonstrate a role for genetic variations in the estrogen receptor alpha gene in determining adult stature in women...
  3. ncbi request reprint Vitamin D receptor gene haplotype is associated with body height and bone size
    Yue Fang
    Genetic Laboratory, Room Ee575, Department of Internal Medicine, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:1491-501. 2007
    ..We recently identified promoter and 3'-untranslated region (UTR) haplotype alleles that influence vitamin D receptor (VDR) mRNA expression...
  4. pmc Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Am J Hum Genet 77:807-23. 2005
    ..This could impact the vitamin D signaling efficiency and might contribute to the increased fracture risk we observed for these risk haplotype alleles...
  5. pmc Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
    Andre G Uitterlinden
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Hum Genet 75:1032-45. 2004
    ..02). The molecular mechanism whereby these moderate SOST genotype effects are mediated remains to be elucidated, but it is likely to involve differences in regulation of SOST gene expression...
  6. ncbi request reprint Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly
    Yue Fang
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Bone Miner Res 18:1632-41. 2003
    ..Our findings expand previous similar findings in a Japanese study to whites and show a relationship with fracture risk of this functional polymorphism...
  7. ncbi request reprint Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women
    Arjan P Bergink
    Erasmus University Medical Center, Rotterdam, The Netherlands
    Arthritis Rheum 48:1913-22. 2003
    ..We studied the association between polymorphisms in the estrogen receptor alpha (ERalpha) gene and the prevalence of radiographic OA of the knee...
  8. ncbi request reprint Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: a meta-analysis
    Yue Fang
    Department of Internal Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands
    Bone 39:938-45. 2006
    ..The vitamin D receptor (VDR) gene is thought to be a candidate gene for osteoporosis. Many genetic studies have suggested an association of VDR polymorphisms and osteoporosis, but evidence remains conflicting...
  9. ncbi request reprint Genetics and biology of vitamin D receptor polymorphisms
    Andre G Uitterlinden
    Genetic Laboratory, Room Ee575, Department of Internal Medicine, Erasmus MC, Dr Molewaterplein 50, PO Box 1738, NL 3000 DR Rotterdam, The Netherlands
    Gene 338:143-56. 2004
    ..Substantial progress has been made that will deepen our understanding of variability in the vitamin D endocrine system and might find applications in risk assessment of disease and in predicting response-to-treatment...
  10. ncbi request reprint The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis
    Andre G Uitterlinden
    Erasmus MC, Rotterdam, The Netherlands
    Ann Intern Med 145:255-64. 2006
    ..Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the genetic regulation of bone mineral density (BMD). However, the clinical impact of these variants remains unclear...
  11. ncbi request reprint Vitamin D receptor gene polymorphisms in relation to Vitamin D related disease states
    Andre G Uitterlinden
    Department of Internal Medicine, Erasmus University Rotterdam Medical Centre, P O Box 1738, Genetic Laboratory, Room Ee575, NL 3000 DR Rotterdam, The Netherlands
    J Steroid Biochem Mol Biol 89:187-93. 2004
    ..Eventually, results of this research will deepen our understanding of variability in the Vitamin D endocrine system and might find applications in risk-assessment of disease and in predicting response-to-treatment...
  12. ncbi request reprint Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk
    Joyce B J van Meurs
    Department of Internal Medicine, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Hum Mol Genet 12:1745-54. 2003
    ..The molecular mechanism underlying this association needs further study...
  13. ncbi request reprint The role of vitamin D receptor gene polymorphisms in bone biology
    Andre G Uitterlinden
    Genomic Laboratory Room Ee575, Department of Internal Medicine, Erasmus University Medical School, Dr Molewaterplein 50, PO Box 1738, GD 3015 Rotterdam, The Netherlands
    Mol Cell Endocrinol 197:15-21. 2002
    ..The ultimate goal of this approach is to identify the combinations of functional sequence variants that modulate the vitamin D endocrine system and confer risk of disease...
  14. ncbi request reprint Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene
    Mark Claassen
    Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    FEMS Immunol Med Microbiol 43:173-6. 2005
    ..Our study into genetic determinants of S. aureus carriage patterns is the largest in the field, but still we found no association between VDR gene variation and S. aureus nasal carriage...