George Anderson

Summary

Affiliation: Faculty of Medicine

Publications

  1. doi request reprint Biological underpinnings of the commonalities in depression, somatization, and Chronic Fatigue Syndrome
    George Anderson
    CRC, Rm 30, 57 Laurel St, Glasgow, G11 7QT Scotland, United Kingdom
    Med Hypotheses 78:752-6. 2012
  2. ncbi request reprint Gut Permeability and Microbiota in Parkinson's Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatoninergic Pathways
    George Anderson
    Head of Research, CRC Scotland and London, United Kingdom
    Curr Pharm Des . 2016
  3. ncbi request reprint Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes
    Timothy V Beischlag
    CRC Scotland and London, London, United Kingdom
    Curr Pharm Des 22:1033-48. 2016
  4. ncbi request reprint Bipolar Disorder: The Role of the Kynurenine and Melatonergic Pathways
    George Anderson
    Head of Research, CRC Scotland and London, UK
    Curr Pharm Des 22:987-1012. 2016
  5. doi request reprint Multiple sclerosis: the role of melatonin and N-acetylserotonin
    George Anderson
    CRC Scotland and London, Eccleston Square, London, UK Electronic address
    Mult Scler Relat Disord 4:112-23. 2015
  6. doi request reprint Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites
    George Anderson
    CRC Scotland and London, Eccleston Square, London, UK
    Curr Psychiatry Rep 17:8. 2015
  7. ncbi request reprint Local melatonin regulates inflammation resolution: a common factor in neurodegenerative, psychiatric and systemic inflammatory disorders
    George Anderson
    George Anderson, CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    CNS Neurol Disord Drug Targets 13:817-27. 2014
  8. ncbi request reprint Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications
    George Anderson
    CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    Curr Pharm Des 20:3812-47. 2014
  9. pmc Postpartum depression: psychoneuroimmunological underpinnings and treatment
    George Anderson
    CRC Clincial Research Centre Communications, Glasgow, Scotland
    Neuropsychiatr Dis Treat 9:277-87. 2013
  10. doi request reprint Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins
    George Anderson
    CRC, Rm 30, 57 Laurel St, Glasgow, G11 7QT, Scotland, UK
    Mol Neurobiol 49:771-83. 2014

Collaborators

Detail Information

Publications27

  1. doi request reprint Biological underpinnings of the commonalities in depression, somatization, and Chronic Fatigue Syndrome
    George Anderson
    CRC, Rm 30, 57 Laurel St, Glasgow, G11 7QT Scotland, United Kingdom
    Med Hypotheses 78:752-6. 2012
    ..Similar somatic symptoms are key components of depression and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)...
  2. ncbi request reprint Gut Permeability and Microbiota in Parkinson's Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatoninergic Pathways
    George Anderson
    Head of Research, CRC Scotland and London, United Kingdom
    Curr Pharm Des . 2016
    ..Although a wide array of data on the biological underpinnings of PD has not yet been linked to such gut-associated changes, increased gut permeability and dysregulated microbiota alter many pathways germane to PD...
  3. ncbi request reprint Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes
    Timothy V Beischlag
    CRC Scotland and London, London, United Kingdom
    Curr Pharm Des 22:1033-48. 2016
    ..Consequently, the melatoninergic pathways may be a significant pharmaceutical target for the treatment of this still very poorly managed condition. ..
  4. ncbi request reprint Bipolar Disorder: The Role of the Kynurenine and Melatonergic Pathways
    George Anderson
    Head of Research, CRC Scotland and London, UK
    Curr Pharm Des 22:987-1012. 2016
    ..We then look at the future directions such research may take. ..
  5. doi request reprint Multiple sclerosis: the role of melatonin and N-acetylserotonin
    George Anderson
    CRC Scotland and London, Eccleston Square, London, UK Electronic address
    Mult Scler Relat Disord 4:112-23. 2015
    ..Here we review the role of local melatonin and its precursors, N-acetylserotonin and serotonin, in MS. ..
  6. doi request reprint Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites
    George Anderson
    CRC Scotland and London, Eccleston Square, London, UK
    Curr Psychiatry Rep 17:8. 2015
    ..Immune-inflammatory, O&NS and TRYCAT pathways are also likely to be relevant biological underpinnings to the significant decrease in life expectancy in BD. ..
  7. ncbi request reprint Local melatonin regulates inflammation resolution: a common factor in neurodegenerative, psychiatric and systemic inflammatory disorders
    George Anderson
    George Anderson, CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    CNS Neurol Disord Drug Targets 13:817-27. 2014
    ..Glia melatonin and NAS regulation are important treatment targets in psychiatric disorders, neurodegenerative disorders and glioma. ..
  8. ncbi request reprint Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications
    George Anderson
    CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    Curr Pharm Des 20:3812-47. 2014
    ....
  9. pmc Postpartum depression: psychoneuroimmunological underpinnings and treatment
    George Anderson
    CRC Clincial Research Centre Communications, Glasgow, Scotland
    Neuropsychiatr Dis Treat 9:277-87. 2013
    ....
  10. doi request reprint Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins
    George Anderson
    CRC, Rm 30, 57 Laurel St, Glasgow, G11 7QT, Scotland, UK
    Mol Neurobiol 49:771-83. 2014
    ..We review this data here in the context of neurodegeneration in Parkinson's disease and to the future directions indicated for slowing disease progression. ..
  11. ncbi request reprint Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions
    George Anderson
    CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    CNS Neurol Disord Drug Targets 13:126-36. 2014
    ....
  12. ncbi request reprint TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease
    George Anderson
    George Anderson, CRC, Rm 30, 57 Laurel St Glasgow G11 7QT, Scotland
    CNS Neurol Disord Drug Targets 13:137-49. 2014
    ..As a consequence, the data reviewed here has treatment implications; relevant to both the course of PD and in the management of L-DOPA induced dyskinesias. ..
  13. pmc Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells
    Elina M Sutinen
    University of Eastern Finland, Institute of Clinical Medicine Neurology, Canthia, FI 70211, Kuopio, Finland
    J Neuroinflammation 9:199. 2012
    ..Elevated IL-18 has been detected in several risk conditions for AD, including obesity, type-II diabetes, and cardiovascular diseases as well as in stress...
  14. pmc A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior
    Gerwyn Morris
    Tir Na Nog, Bryn Road Seaside 87, Llanelli SA152LW, UK
    BMC Med 11:64. 2013
    ..It is concluded that sickness behavior and ME/CFS are two different conditions. ..
  15. pmc Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
    Michael Maes
    Maes Clinics TRIA, Piyavate Hospital, 998 Rimklongsamsen Road, Bangkok 10310, Thailand
    BMC Med 10:66. 2012
    ....
  16. doi request reprint Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects
    George Anderson
    CRC, Glasgow, Scotland, UK
    Metab Brain Dis 27:113-9. 2012
    ..Melatonin is likely to have impacts on the metabolic side effects of anti-psychotics that contribute to subsequent decreases in life-expectancy...
  17. doi request reprint The role of melatonin in post-partum psychosis and depression associated with bipolar disorder
    George Anderson
    Clinical Research Centre Communications, Glasgow, UK
    J Perinat Med 38:585-7. 2010
    ..It is proposed that the optimization of melatonin levels, perhaps in conjunction with optimized vitamin D3 level, would decrease post-partum psychosis and depression associated with BD...
  18. doi request reprint Neuronal-immune interactions in mediating stress effects in the etiology and course of schizophrenia: role of the amygdala in developmental co-ordination
    George Anderson
    CRC, 1229 Dumbarton Road, Glasgow, Scotland, UK
    Med Hypotheses 76:54-60. 2011
    ..The likely involvement of glia in mediating increases in the KP products suggests that adaptation to stress is driven by neuronal activity as a form of glia to glia communication...
  19. doi request reprint Multiple sclerosis, seizures, and antiepileptics: role of IL-18, IDO, and melatonin
    G Anderson
    CRC, Glasgow, Scotland
    Eur J Neurol 18:680-5. 2011
    ..Antiepileptic drugs modulate wider MS symptomatology, interacting with melatonin and vitamin D3. This manuscript provides a framework for the wider understanding and treatment of seizures in MS and wider MS symptomatology...
  20. doi request reprint Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways
    George Anderson
    CRC, Rm 30, Glasgow, Scotland, United Kingdom
    Prog Neuropsychopharmacol Biol Psychiatry 42:101-14. 2013
    ....
  21. doi request reprint Schizophrenia: linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression
    George Anderson
    CRC, Rm 30, Glasgow, Scotland, United Kingdom
    Prog Neuropsychopharmacol Biol Psychiatry 42:5-19. 2013
    ....
  22. doi request reprint Inflammation-related disorders in the tryptophan catabolite pathway in depression and somatization
    George Anderson
    CRC, Glasgow, UK
    Adv Protein Chem Struct Biol 88:27-48. 2012
    ..We lastly review new pathophysiologically driven drug candidates for somatization, including St. John's wort, resveratrol, melatonin, agomelatine, Garcinia mangostana (γ-mangostin), N-acetyl cysteine, and pamoic acid...
  23. doi request reprint The circadian clock circuitry and the AHR signaling pathway in physiology and pathology
    George Anderson
    Clinical Research Centre Communications, Glasgow, United Kingdom
    Biochem Pharmacol 85:1405-16. 2013
    ..On the other hand, the molecular components of the circadian clock circuitry and AHR signaling pathway may represent useful tools for preventive interventions and valuable targets of therapeutic approaches...
  24. doi request reprint Ebola virus: melatonin as a readily available treatment option
    George Anderson
    CRC Scotland and London, Eccleston Square, London, United Kingdom
    J Med Virol 87:537-43. 2015
    ..Although no direct data pertain to the utility of melatonin in the management of the Ebola virus, convergent bodies of data suggest its utility, which is reviewed in this article...
  25. ncbi request reprint Increased IL-6 trans-signaling in depression: focus on the tryptophan catabolite pathway, melatonin and neuroprogression
    George Anderson
    CRC Clinical Research Centre Communications, Rm 30, 57 Laurel Street, Glasgow, G11 7QT, Scotland
    Pharmacol Rep 65:1647-54. 2013
    ....
  26. doi request reprint Role of immune-inflammatory and oxidative and nitrosative stress pathways in the etiology of depression: therapeutic implications
    George Anderson
    CRC, Rm 30, 57 Laurel Street, Glasgow, G11 7QT, Scotland
    CNS Drugs 28:1-10. 2014
    ..The use of such a frame of reference and the treatment benefits attained are likely to have wider implications and utility for depression-associated conditions, including the neuroinflammatory and (neuro)degenerative disorders. ..
  27. ncbi request reprint How Immune-inflammatory processes link CNS and psychiatric disorders: Classification and Treatment Implications
    George Anderson
    CRC Scotland and London, Eccleston Square London, United Kingdom
    CNS Neurol Disord Drug Targets . 2016
    ....