Genomes and Genes
Affiliation: Tallinn University of Technology
- Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cellsAlla Piirsoo
Protobios LLC, Mäealuse 4, Tallinn 12618, Estonia Cellin Technologies LLC, Mäealuse 4, Tallinn 12618, Estonia Electronic address
Biochim Biophys Acta 1843:703-14. 2014..Our data suggest SU6668 as an efficient inhibitor of Ulk3 kinase allowing manipulation of the Gli-dependent transcriptional outcome. ..
- Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathwayAlla Maloverjan
Department of Gene Technology, Tallinn University of Technology, Akadeemia tee 15, 12618 Tallinn, Estonia
Exp Cell Res 316:627-37. 2010..Our data suggest that serine/threonine kinase ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins...
- Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayAlla Maloverjan
Department of Gene Technology, Institute of Clinical Medicine, Tallinn University of Technology, Akadeemia tee 15, 12618 Tallinn, Estonia
J Biol Chem 285:30079-90. 2010..Our data suggests a dual function of Ulk3 in the Shh signal transduction pathway and propose an additional way of regulating Gli proteins by Sufu, through binding to and suppression of Ulk3...