Floyd Dukes

Summary

Publications

  1. pmc Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes
    Floyd Dukes
    Department of Medicine, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, PA 19104, USA
    BMC Complement Altern Med 12:47. 2012
  2. pmc Radiation mitigating properties of the lignan component in flaxseed
    Ralph Pietrofesa
    Department of Medicine, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, 3615 Civic Center Boulevard, Abramson Research Building, Suite 1016C, Philadelphia, PA 19104, USA
    BMC Cancer 13:179. 2013
  3. pmc Radioprotective role in lung of the flaxseed lignan complex enriched in the phenolic secoisolariciresinol diglucoside (SDG)
    Melpo Christofidou-Solomidou
    Department of Medicine, Pulmonary Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Radiat Res 178:568-80. 2012
  4. pmc Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice
    Melpo Christofidou-Solomidou
    Department of Medicine, Pulmonary Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    BMC Cancer 11:269. 2011

Detail Information

Publications4

  1. pmc Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes
    Floyd Dukes
    Department of Medicine, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, PA 19104, USA
    BMC Complement Altern Med 12:47. 2012
    ..We therefore postulated that flaxseed might modulate gene expression of vital signaling pathways, thus interfering with the development of tissue injury...
  2. pmc Radiation mitigating properties of the lignan component in flaxseed
    Ralph Pietrofesa
    Department of Medicine, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, 3615 Civic Center Boulevard, Abramson Research Building, Suite 1016C, Philadelphia, PA 19104, USA
    BMC Cancer 13:179. 2013
    ..This could potentially lead to pulmonary inflammation, oxidative tissue injury, and fibrosis. This study aimed to evaluate the radiation mitigating effects of FLC in a mouse model of radiation pneumonopathy...
  3. pmc Radioprotective role in lung of the flaxseed lignan complex enriched in the phenolic secoisolariciresinol diglucoside (SDG)
    Melpo Christofidou-Solomidou
    Department of Medicine, Pulmonary Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Radiat Res 178:568-80. 2012
    ..The dietary lignan complex of FS, mainly consisting of the phenolic secoisolariciresinol, is protective against radiation pneumonopathy in vivo while not hindering the tumoricidal effects of radiotherapy...
  4. pmc Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice
    Melpo Christofidou-Solomidou
    Department of Medicine, Pulmonary Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    BMC Cancer 11:269. 2011
    ..We previously reported that dietary FS prevents pneumonopathy in a rodent model of thoracic X-ray radiation therapy (XRT). However, flaxseed's therapeutic usefulness in mitigating radiation effects post-exposure has never been evaluated...