Stavros G Drakos

Summary

Publications

  1. pmc Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization
    Stavros G Drakos
    Utah Transplant Affiliated Hospitals UTAH Cardiac Transplant Program, Salt Lake City, UT 84112, USA
    J Heart Lung Transplant 28:838-42. 2009
  2. doi request reprint Pulsatility and the risk of nonsurgical bleeding in patients supported with the continuous-flow left ventricular assist device HeartMate II
    Omar Wever-Pinzon
    Utah Transplantation Affiliated Hospitals, Cardiac Transplant Program, Salt Lake City, UT, USA
    Circ Heart Fail 6:517-26. 2013
  3. pmc Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified?
    Omar Wever-Pinzon
    U T A H Cardiac Transplant Program, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Circulation 127:452-62. 2013
  4. doi request reprint A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation
    Abdallah G Kfoury
    Intermountain Medical Center and Intermountain Healthcare, Salt Lake City, Utah, USA
    J Heart Lung Transplant 31:46-51. 2012
  5. ncbi request reprint Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: the impact of leukofiltered cellular blood product transfusions
    Stavros G Drakos
    Utah Transplantation Affiliated Hospitals UTAH Cardiac Transplant Program, Salt Lake City, Utah, USA
    J Thorac Cardiovasc Surg 133:1612-9. 2007
  6. ncbi request reprint Low-dose prophylactic intravenous immunoglobulin does not prevent HLA sensitization in left ventricular assist device recipients
    Stavros G Drakos
    LDS Hospital, University of Utah School of Medicine, Utah Transplantation Affiliated Hospitals Cardiac Transplant Program, Salt Lake City, Utah 84143, USA
    Ann Thorac Surg 82:889-93. 2006
  7. doi request reprint Impact of ventricular assist device complications on posttransplant survival: an analysis of the United network of organ sharing database
    Aaron H Healy
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Ann Thorac Surg 95:870-5. 2013
  8. doi request reprint Cardiac Recovery During Long-Term Left Ventricular Assist Device Support
    Omar Wever-Pinzon
    Utah Cardiac Recovery Program, Salt Lake City, Utah Division of Cardiology, University of Utah School of Medicine, Salt Lake City, Utah Veterans Affairs Medical Center, Salt Lake City, Utah
    J Am Coll Cardiol 68:1540-53. 2016
  9. pmc Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation
    Osama M Abdullah
    Department of Bioengineering, University of Utah, Salt Lake City, UT, USA
    NMR Biomed 27:1378-86. 2014
  10. doi request reprint Improved survival in heart transplant patients living at high altitude
    Curtis J Wozniak
    Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT 84132 2101, USA
    J Thorac Cardiovasc Surg 143:735-741.e1. 2012

Collaborators

Detail Information

Publications27

  1. pmc Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization
    Stavros G Drakos
    Utah Transplant Affiliated Hospitals UTAH Cardiac Transplant Program, Salt Lake City, UT 84112, USA
    J Heart Lung Transplant 28:838-42. 2009
    ..04). Pre-sensitized patients are at higher risk for becoming and remaining highly HLA-allosensitized after LVAD implantation. The HeartMate II LVAD appears to cause less sensitization than HeartMate I...
  2. doi request reprint Pulsatility and the risk of nonsurgical bleeding in patients supported with the continuous-flow left ventricular assist device HeartMate II
    Omar Wever-Pinzon
    Utah Transplantation Affiliated Hospitals, Cardiac Transplant Program, Salt Lake City, UT, USA
    Circ Heart Fail 6:517-26. 2013
    ..Reduced pulsatility has been implicated as a contributing cause. The aim of this study was to assess the effects of different degrees of pulsatility on the incidence of nonsurgical bleeding...
  3. pmc Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified?
    Omar Wever-Pinzon
    U T A H Cardiac Transplant Program, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Circulation 127:452-62. 2013
    ..Survival of patients on left ventricular assist devices (LVADs) has improved. We examined the differences in risk of adverse outcomes between LVAD-supported and medically managed candidates on the heart transplant waiting list...
  4. doi request reprint A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation
    Abdallah G Kfoury
    Intermountain Medical Center and Intermountain Healthcare, Salt Lake City, Utah, USA
    J Heart Lung Transplant 31:46-51. 2012
    ..Debate continues about whether therapeutic intervention is warranted to avoid adverse outcomes. In this study we examine the course of individual episodes of untreated asymptomatic AMR on follow-up endomyocardial biopsy (EMB)...
  5. ncbi request reprint Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: the impact of leukofiltered cellular blood product transfusions
    Stavros G Drakos
    Utah Transplantation Affiliated Hospitals UTAH Cardiac Transplant Program, Salt Lake City, Utah, USA
    J Thorac Cardiovasc Surg 133:1612-9. 2007
    ..We investigated the pattern of sensitization in left ventricular assist device recipients in relation to cellular blood product transfusions received...
  6. ncbi request reprint Low-dose prophylactic intravenous immunoglobulin does not prevent HLA sensitization in left ventricular assist device recipients
    Stavros G Drakos
    LDS Hospital, University of Utah School of Medicine, Utah Transplantation Affiliated Hospitals Cardiac Transplant Program, Salt Lake City, Utah 84143, USA
    Ann Thorac Surg 82:889-93. 2006
    ....
  7. doi request reprint Impact of ventricular assist device complications on posttransplant survival: an analysis of the United network of organ sharing database
    Aaron H Healy
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Ann Thorac Surg 95:870-5. 2013
    ..We sought to determine if the presence or absence of complications in status 1A LVAD patients at the time of transplant influenced survival after transplant...
  8. doi request reprint Cardiac Recovery During Long-Term Left Ventricular Assist Device Support
    Omar Wever-Pinzon
    Utah Cardiac Recovery Program, Salt Lake City, Utah Division of Cardiology, University of Utah School of Medicine, Salt Lake City, Utah Veterans Affairs Medical Center, Salt Lake City, Utah
    J Am Coll Cardiol 68:1540-53. 2016
    ..The number of centers with left ventricular assist device (LVAD) research programs focused on cardiac recovery is very small. Therefore, this phenomenon has been reported in real-world multi-center registries as a rare event...
  9. pmc Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation
    Osama M Abdullah
    Department of Bioengineering, University of Utah, Salt Lake City, UT, USA
    NMR Biomed 27:1378-86. 2014
    ..Combined, these findings suggest that scalar DTI parameters can be used as metrics for the non-invasive assessment of diffuse fibrosis in failing hearts...
  10. doi request reprint Improved survival in heart transplant patients living at high altitude
    Curtis J Wozniak
    Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT 84132 2101, USA
    J Thorac Cardiovasc Surg 143:735-741.e1. 2012
    ..The purpose of the present study was to determine whether altitude negatively affects survival among patients undergoing heart transplantation...
  11. pmc Left ventricular assist device unloading effects on myocardial structure and function: current status of the field and call for action
    Stavros G Drakos
    UTAH Cardiac Transplant Program, Division of Cardiology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Curr Opin Cardiol 26:245-55. 2011
    ..Herein, we summarize and integrate insights from studies which investigated how LVAD unloading influences the structure and function of the failing human heart...
  12. doi request reprint Cardiovascular mortality among heart transplant recipients with asymptomatic antibody-mediated or stable mixed cellular and antibody-mediated rejection
    Abdallah G Kfoury
    Intermountain Medical Center and Intermountain Healthcare, Salt Lake City, UT, USA
    J Heart Lung Transplant 28:781-4. 2009
    ..In this study, we examined whether a differential impact on cardiovascular mortality (CVM) existed when comparing asymptomatic AMR, to stable MR or CR...
  13. doi request reprint ISHLT pathology antibody mediated rejection score correlates with increased risk of cardiovascular mortality: A retrospective validation analysis
    M Elizabeth H Hammond
    Utah Transplantation Affiliated Hospitals Cardiac Transplant Program, Salt Lake City, Utah Department of Pathology, Intermountain Medical Center and Intermountain Healthcare, Salt Lake City, Utah Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah Electronic address
    J Heart Lung Transplant 35:320-5. 2016
    ..We sought to determine whether the ISHLT pAMR grading schema correlates with patient outcomes...
  14. doi request reprint Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery
    Nikolaos A Diakos
    Utah Transplantation Affiliated Hospitals UTAH Cardiac Transplant Program Divisions of Cardiovascular Medicine and Cardiothoracic Surgery, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah University of Utah Molecular Medicine Program, Salt Lake City, Utah
    J Am Coll Cardiol 64:1602-12. 2014
    ..However, whether unloading-induced atrophy in experimental normal heart models applies to failing and hypertrophic myocardium in heart failure patients unloaded by continuous-flow LVADs has not been studied...
  15. doi request reprint Changing outcomes in patients bridged to heart transplantation with continuous- versus pulsatile-flow ventricular assist devices: an analysis of the registry of the International Society for Heart and Lung Transplantation
    Jose N Nativi
    Department of Medicine, Division of Cardiology, University of Utah, Salt Lake City, Utah 84132, USA
    J Heart Lung Transplant 30:854-61. 2011
    ..Our aim was to determine the impact of the type of LVAD and implant era on post-transplant survival...
  16. pmc Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart
    Stavros G Drakos
    Cardiovascular Department and Utah Artificial Heart Program, Intermountain Medical Center, Salt Lake City, Utah, USA
    J Am Coll Cardiol 56:382-91. 2010
    ..This study investigates alterations in myocardial microvasculature, fibrosis, and hypertrophy before and after mechanical unloading of the failing human heart...
  17. ncbi request reprint Effect of reversible pulmonary hypertension on outcomes after heart transplantation
    Stavros G Drakos
    Utah Transplantation Affiliated Hospitals, Cardiac Transplant Program, LDS Hospital, Salt Lake City, Utah 84143, USA
    J Heart Lung Transplant 26:319-23. 2007
    ..Conflicting data exist regarding the impact of reversible pulmonary hypertension (PHTN) on post-transplant (Tx) outcomes. In this study we sought to determine the influence of reversible PHTN on outcomes after Tx...
  18. doi request reprint Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations
    Abdallah G Kfoury
    Intermountain Heart Institute and Intermountain Healthcare, Murray, Utah University of Utah School of Medicine, Salt Lake City, Utah Utah Transplantation Affiliated Hospitals U T A H Cardiac Transplant Program, Salt Lake City, Utah Electronic address
    J Heart Lung Transplant 35:335-41. 2016
    ..In this study we systematically explore the pathologic and clinical characteristics of MR in heart transplantation...
  19. pmc Magnitude and time course of changes induced by continuous-flow left ventricular assist device unloading in chronic heart failure: insights into cardiac recovery
    Stavros G Drakos
    Utah Transplantation Affiliated Hospitals UTAH Cardiac Transplant Program, Divisions of Cardiology and Cardiothoracic Surgery, University of Utah Health Sciences Center, Intermountain Medical Center, Salt Lake City, Utah 84132, USA
    J Am Coll Cardiol 61:1985-94. 2013
    ..This study sought to prospectively investigate the longitudinal effects of continuous-flow left ventricular assist device (LVAD) unloading on myocardial structure and systolic and diastolic function...
  20. doi request reprint Risk factors predictive of right ventricular failure after left ventricular assist device implantation
    Stavros G Drakos
    Cardiovascular Department, Intermountain Medical Center, Salt Lake City, Utah University of Utah School of Medicine, Salt Lake City, Utah, USA
    Am J Cardiol 105:1030-5. 2010
    ....
  21. doi request reprint Allograft rejection in patients supported with continuous-flow left ventricular assist devices
    Aaron H Healy
    UTAH Utah Transplant Affiliated Hospitals Cardiac Transplant Program, University of Utah, Salt Lake City, Utah 84132, USA
    Ann Thorac Surg 92:1601-7; discussion 1607. 2011
    ..We sought to analyze the relationship between LVAD flow characteristics and subsequent allograft rejection in bridge to transplant (BTT) patients...
  22. doi request reprint Elevated resting heart rate in heart transplant recipients: innocent bystander or adverse prognostic indicator?
    S Blake Wachter
    School of Medicine, University of Utah, Salt Lake City, UT, USA
    Clin Transplant 29:829-34. 2015
    ..However, we hypothesized that a resting HR above 100 beats per minute (bpm) may be associated with morbidity and mortality...
  23. ncbi request reprint Multivariate predictors of heart transplantation outcomes in the era of chronic mechanical circulatory support
    Stavros G Drakos
    LDS Hospital, Salt Lake City, Utah 84143, USA
    Ann Thorac Surg 83:62-7. 2007
    ..Determining which pretransplantation (TX) characteristics predict the development of chronic renal dysfunction (CRD) or death after heart TX would enable more accurate risk assessment at the time of candidate evaluation...
  24. pmc Further Peripheral Vascular Dysfunction in Heart Failure Patients With a Continuous-Flow Left Ventricular Assist Device: The Role of Pulsatility
    Melissa A H Witman
    Geriatric Research, Education, and Clinical Center, George E Whalen VA Medical Center, Salt Lake City, Utah Department of Internal Medicine, Division of Geriatrics, George E Whalen VA Medical Center and University of Utah Medical Center, University of Utah School of Medicine, Salt Lake City, Utah Electronic address
    JACC Heart Fail 3:703-11. 2015
    ..Using flow-mediated vasodilation (FMD) and reactive hyperemia (RH), this study aimed to provide greater insight into left ventricular assist device (LVAD)-induced changes in peripheral vascular function...
  25. pmc Vascular leak is a central feature in the pathogenesis of systemic sclerosis
    Tracy M Frech
    Division of Rheumatology, Department of Internal Medicine, University of Utah, 4B200 SOM, 30 N 1900 E, Salt Lake City, Utah 84132, USA
    J Rheumatol 39:1385-91. 2012
    ..We investigated the microvasculature alterations in the skin of patients with SSc at various stages of disease duration with whole-field digital microscopy...
  26. pmc Baseline red blood cell osmotic fragility does not predict the degree of post-LVAD hemolysis
    Jesse L Madden
    From the Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah Division of Cardiology, University of Utah, Salt Lake City, Utah and Department of Molecular Medicine, University of Utah, Salt Lake City, Utah
    ASAIO J 60:524-8. 2014
    ..Mechanical forces generated by existing LVADs result in similar levels of biochemical hemolysis, as assessed by LDH, despite baseline differences in a patient's osmotic red-cell fragility. ..
  27. ncbi request reprint Effect of mechanical circulatory support on outcomes after heart transplantation
    Stavros G Drakos
    Utah Transplantation Affiliate Hospitals Cardiac Transplant Program, Salt Lake City, UT, USA
    J Heart Lung Transplant 25:22-8. 2006
    ....