Rahul Deshmukh

Summary

Publications

  1. doi request reprint Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats
    Rahul Deshmukh
    Neuropharmacology Division, I S F College of Pharmacy, Moga 142001, Punjab, India Electronic address
    Biomed Pharmacother 81:56-62. 2016
  2. doi request reprint Stimulation of accumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats
    Rahul R Deshmukh
    Neuropharmacology Division, ISF College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Res 66:276-82. 2012
  3. doi request reprint Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine -- a PDE1 inhibitor
    Rahul Deshmukh
    Division of Neuropharmacology, Department of Pharmacology, ISF College of Pharmacy, Punjab, India
    Eur J Pharmacol 620:49-56. 2009
  4. doi request reprint Pharmacological induction of hemeoxygenase-1 activity attenuates intracerebroventricular streptozotocin induced neurocognitive deficit and oxidative stress in rats
    Manveen Bhardwaj
    Department of Pharmacology, I S F College of Pharmacy, Moga, Punjab, India
    Eur J Pharmacol 772:43-50. 2016
  5. doi request reprint Neuroprotective effect of RO-20-1724-a phosphodiesterase4 inhibitor against intracerebroventricular streptozotocin induced cognitive deficit and oxidative stress in rats
    Vivek Sharma
    Neuropharmacology Div, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Biochem Behav 101:239-45. 2012
  6. doi request reprint SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats
    Nidhi Sharma
    Neuropharmacology Division, Department of Pharmacology, I S F College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Biochem Behav 96:386-94. 2010
  7. doi request reprint Ameliorating effect of lyophilized extract of Butea frondosa leaves on scopolamine-induced amnesia in rats
    Jai Malik
    Department of Pharmacognosy and Herbal Drug Technology, ISF College of Pharmacy, Moga, Punjab, India
    Pharm Biol 51:233-9. 2013
  8. doi request reprint Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation
    Swati Datta
    Department of Pharmacology, I S F College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 771:229-35. 2016
  9. doi request reprint Neuroprotective role of PDE4 and PDE5 inhibitors in 3-nitropropionic acid induced behavioral and biochemical toxicities in rats
    Tarun Thakur
    Neuropharmacology Division, ISF College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 714:515-21. 2013
  10. doi request reprint Phosphodiesterases: Regulators of cyclic nucleotide signals and novel molecular target for movement disorders
    Sorabh Sharma
    Neuropharmacology Division, I S F College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 714:486-97. 2013

Collaborators

  • Puneet Kumar
  • Nidhi Sharma
  • Ashok Kumar
  • Sidharth Mehan
  • Jai Malik
  • Kushal Kumar
  • Sorabh Sharma
  • Jitender Bariwal
  • Swati Datta
  • Ganesh Singh Bhakuni
  • Vanita Rani
  • Manveen Bhardwaj
  • Neha Soni
  • Tarun Thakur
  • Pyare Lal Sharma
  • Ankita Mehta
  • P L Sharma
  • Vivek Sharma
  • Priya Jaswal
  • Madhu Kaundal
  • Onkar Bedi
  • B V Krishna Reddy
  • Sumit Jamwal
  • Prashant Koushal
  • B V K Reddy
  • Mayank Prabhakar
  • K L Bedi
  • Ashu Bala

Detail Information

Publications18

  1. doi request reprint Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats
    Rahul Deshmukh
    Neuropharmacology Division, I S F College of Pharmacy, Moga 142001, Punjab, India Electronic address
    Biomed Pharmacother 81:56-62. 2016
    ..Our results suggest the therapeutic potential of caffeic acid in cognitive disorders such as AD. ..
  2. doi request reprint Stimulation of accumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats
    Rahul R Deshmukh
    Neuropharmacology Division, ISF College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Res 66:276-82. 2012
    ..Altogether these findings reinforce the idea that the endogenous cannabinoid system in the accumbens shell may be important to augment reward-driven feeding via modulation of CB(1) receptor signalling pathways...
  3. doi request reprint Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine -- a PDE1 inhibitor
    Rahul Deshmukh
    Division of Neuropharmacology, Department of Pharmacology, ISF College of Pharmacy, Punjab, India
    Eur J Pharmacol 620:49-56. 2009
    ..The observed beneficial effects of vinpocetine on spatial memory may be due to its ability to favorably modulate cholinergic functions, prevent neuronal cell damage and possibly through its antioxidant mechanism also...
  4. doi request reprint Pharmacological induction of hemeoxygenase-1 activity attenuates intracerebroventricular streptozotocin induced neurocognitive deficit and oxidative stress in rats
    Manveen Bhardwaj
    Department of Pharmacology, I S F College of Pharmacy, Moga, Punjab, India
    Eur J Pharmacol 772:43-50. 2016
    ..The observed beneficial effects of hemin on spatial memory may be due to its ability to favorably modulate HO-1 pathway and antioxidant mechanisms. ..
  5. doi request reprint Neuroprotective effect of RO-20-1724-a phosphodiesterase4 inhibitor against intracerebroventricular streptozotocin induced cognitive deficit and oxidative stress in rats
    Vivek Sharma
    Neuropharmacology Div, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Biochem Behav 101:239-45. 2012
    ..The observed beneficial effects of RO-20-1724 in spatial memory may be due to its ability to restore cholinergic functions and possibly through its antioxidant mechanisms...
  6. doi request reprint SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats
    Nidhi Sharma
    Neuropharmacology Division, Department of Pharmacology, I S F College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Biochem Behav 96:386-94. 2010
    ..In line with previous report, the current study also supports the potential of JNK inhibition as a possible therapeutic strategy to ameliorate neurodegenerative disorders associated with oxidative stress and cognitive impairment...
  7. doi request reprint Ameliorating effect of lyophilized extract of Butea frondosa leaves on scopolamine-induced amnesia in rats
    Jai Malik
    Department of Pharmacognosy and Herbal Drug Technology, ISF College of Pharmacy, Moga, Punjab, India
    Pharm Biol 51:233-9. 2013
    ..amp; Koen. (syn. B. monosperma Lam.) (Fabaceae) leaves have been used in folklore medicine for the treatment of diabetes, conjunctivitis, gastrointestinal tract, and central nervous system disorders such as anxiety, amnesia, etc...
  8. doi request reprint Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation
    Swati Datta
    Department of Pharmacology, I S F College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 771:229-35. 2016
    ..Results of the present study attributed the therapeutic potential of lycopene in the treatment (prevented or delayed) of typical antipsychotic induced orofacial dyskinesia. ..
  9. doi request reprint Neuroprotective role of PDE4 and PDE5 inhibitors in 3-nitropropionic acid induced behavioral and biochemical toxicities in rats
    Tarun Thakur
    Neuropharmacology Division, ISF College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 714:515-21. 2013
    ..These results suggesting that the inhibition of PDE4 and PDE5 would be therapeutic in neurodegenerative disorders associated with cognitive and motor dysfunction...
  10. doi request reprint Phosphodiesterases: Regulators of cyclic nucleotide signals and novel molecular target for movement disorders
    Sorabh Sharma
    Neuropharmacology Division, I S F College of Pharmacy, Moga 142001, Punjab, India
    Eur J Pharmacol 714:486-97. 2013
    ..In this review, we have discussed a putative role of PDE inhibitors in movement disorders and associated abnormalities. ..
  11. doi request reprint Therapeutic potential of GABA(B) receptor ligands in drug addiction, anxiety, depression and other CNS disorders
    Kushal Kumar
    Neuropharmacology Division, Department of Pharmacology, I S F College of Pharmacy, Moga 142001, Punjab, India
    Pharmacol Biochem Behav 110:174-84. 2013
    ..The present review is aimed to discuss the role of GABA(B) receptors and the possible outcomes of GABA(B) receptor modulation in CNS disorders...
  12. doi request reprint Animal models of hepatotoxicity
    Ganesh Singh Bhakuni
    Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, 142001, India
    Inflamm Res 65:13-24. 2016
    ..Liver injury produces pathological changes like increase level of SGOT, SGPT, TB and generation of free radical radicals...
  13. doi request reprint Alzheimer's disease: Is this a brain specific diabetic condition?
    Vanita Rani
    Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India
    Physiol Behav 164:259-67. 2016
    ..This review summarizes the pathways that might link diabetes and AD and the effect of diminished insulin. ..
  14. doi request reprint Herbs to curb cyclic nucleotide phosphodiesterase and their potential role in Alzheimer's disease
    Ashwani Kumar
    Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India
    Mech Ageing Dev 149:75-87. 2015
    ..The present review is aimed to discuss the potential plant extract/compounds with PDE inhibitory activity and critically discuss their potential role in Alzheimer's disease. ..
  15. doi request reprint Effect of GLT-1 modulator and P2X7 antagonists alone and in combination in the kindling model of epilepsy in rats
    Neha Soni
    Department of Pharmacology, ISF College of Pharmacy, Moga 142001, Punjab, India
    Epilepsy Behav 48:4-14. 2015
    ..The study was further extended to elucidate the cross-link between glutamatergic and purinergic pathways in epilepsy...
  16. doi request reprint Effect of licofelone--a dual COX/5-LOX inhibitor in intracerebroventricular streptozotocin-induced behavioral and biochemical abnormalities in rats
    Ashok Kumar
    Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, 142001, India
    J Mol Neurosci 55:749-59. 2015
    ..These observed results suggest the therapeutic potential of dual COX/5-LOX inhibitors in neurodegenerative disorders associated with oxidative stress and cognitive impairment...
  17. doi request reprint Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats
    Pushpender Kumar
    Department of Pharmacology, I S F College of Pharmacy, Ferozepur Road, Ghal Kalan, Moga 142001, Punjab, India
    Eur J Pharmacol 723:38-45. 2014
    ..The results of the present study suggest that the positive GABAergic modulation may be beneficial for the treatment of motor disorder. ..
  18. doi request reprint Excitotoxicity: bridge to various triggers in neurodegenerative disorders
    Ankita Mehta
    Neuropharmacology Division, ISF College of Pharmacy, Ferozpur Road, Ghal Kalan, Moga 142 001, Punjab, India
    Eur J Pharmacol 698:6-18. 2013
    ..Further, a brief introduction about the recent research occurring in the treatment of various neurodegenerative diseases, including a summary of the presumed physiologic mechanisms behind the pharmacology of these disorders...