Christian Wejse

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. doi request reprint Impact of HIV-1, HIV-2, and HIV-1+2 dual infection on the outcome of tuberculosis
    C Wejse
    Bandim Health Project, INDEPTH Network, Statens Serum Institut, Bissau, Guinea Bissau GloHAU, Centre for Global Health, Department of Public Health, Aarhus University, Bartholins Alle 2, 8000 Aarhus C, Denmark Electronic address
    Int J Infect Dis 32:128-34. 2015
  2. doi request reprint Tuberculosis elimination in the post Millennium Development Goals era
    Christian Wejse
    GloHAU, Center for Global Health, School of Public Health, Aarhus University, Bartholins Alle 2, 8000 Aarhus C, Denmark Deparment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, Guinea Bissau Electronic address
    Int J Infect Dis 32:152-5. 2015
  3. doi request reprint Impact of tuberculosis treatment on CD4 cell count, HIV RNA, and p24 antigen in patients with HIV and tuberculosis
    C Wejse
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, 8200 Aarhus N, Denmark GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark Electronic address
    Int J Infect Dis 17:e907-12. 2013
  4. ncbi request reprint [Picture of the month: Mollaret meningitis]
    Christian Wejse
    Arhus Universitetshospital, Skejby Sygehus, Infektionsmedicinsk Afdeling
    Ugeskr Laeger 166:3510. 2004
  5. ncbi request reprint TBscore: Signs and symptoms from tuberculosis patients in a low-resource setting have predictive value and may be used to assess clinical course
    Christian Wejse
    Bandim Health Project, Statens Serum Institute, Bissau, Guinea Bissau
    Scand J Infect Dis 40:111-20. 2008
  6. ncbi request reprint Serum 25-hydroxyvitamin D in a West African population of tuberculosis patients and unmatched healthy controls
    Christian Wejse
    Bandim Health Project, INDEPTH Network, Statens Serum Institut, Bissau, Guinea Bissau, University of Copenhagen, Copenhagen, Denmark
    Am J Clin Nutr 86:1376-83. 2007
  7. doi request reprint Vitamin D as supplementary treatment for tuberculosis: a double-blind, randomized, placebo-controlled trial
    Christian Wejse
    Infectious Disease Research Unit, Aarhus University Hospital, Skejby, Brendstrupgaardsvej, 8200 Aarhus N, Denmark
    Am J Respir Crit Care Med 179:843-50. 2009
  8. doi request reprint Urine suPAR levels compared with plasma suPAR levels as predictors of post-consultation mortality risk among individuals assumed to be TB-negative: a prospective cohort study
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau Codex, Guinea Bissau
    Inflammation 33:374-80. 2010
  9. doi request reprint The Bandim tuberculosis score: reliability and comparison with the Karnofsky performance score
    Frauke Rudolf
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Scand J Infect Dis 45:256-64. 2013
  10. pmc Utility of the plasma level of suPAR in monitoring risk of mortality during TB treatment
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    PLoS ONE 7:e43933. 2012

Collaborators

Detail Information

Publications38

  1. doi request reprint Impact of HIV-1, HIV-2, and HIV-1+2 dual infection on the outcome of tuberculosis
    C Wejse
    Bandim Health Project, INDEPTH Network, Statens Serum Institut, Bissau, Guinea Bissau GloHAU, Centre for Global Health, Department of Public Health, Aarhus University, Bartholins Alle 2, 8000 Aarhus C, Denmark Electronic address
    Int J Infect Dis 32:128-34. 2015
    ..The aim of this study was to assess the impact of HIV types on mortality among TB patients in Guinea-Bissau and to examine the predictive ability of the TBscoreII, a clinical score used to assess disease severity...
  2. doi request reprint Tuberculosis elimination in the post Millennium Development Goals era
    Christian Wejse
    GloHAU, Center for Global Health, School of Public Health, Aarhus University, Bartholins Alle 2, 8000 Aarhus C, Denmark Deparment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, Guinea Bissau Electronic address
    Int J Infect Dis 32:152-5. 2015
    ..Each approach is discussed and a way forward in research and management is suggested. ..
  3. doi request reprint Impact of tuberculosis treatment on CD4 cell count, HIV RNA, and p24 antigen in patients with HIV and tuberculosis
    C Wejse
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, 8200 Aarhus N, Denmark GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark Electronic address
    Int J Infect Dis 17:e907-12. 2013
    ..To describe HIV RNA levels during tuberculosis (TB) infection in patients co-infected with TB and HIV. Moreover, to examine the p24 antigen profile during TB treatment...
  4. ncbi request reprint [Picture of the month: Mollaret meningitis]
    Christian Wejse
    Arhus Universitetshospital, Skejby Sygehus, Infektionsmedicinsk Afdeling
    Ugeskr Laeger 166:3510. 2004
  5. ncbi request reprint TBscore: Signs and symptoms from tuberculosis patients in a low-resource setting have predictive value and may be used to assess clinical course
    Christian Wejse
    Bandim Health Project, Statens Serum Institute, Bissau, Guinea Bissau
    Scand J Infect Dis 40:111-20. 2008
    ..Low TBscore or fall in TBscore at treatment completion may be used as a measure of improvement...
  6. ncbi request reprint Serum 25-hydroxyvitamin D in a West African population of tuberculosis patients and unmatched healthy controls
    Christian Wejse
    Bandim Health Project, INDEPTH Network, Statens Serum Institut, Bissau, Guinea Bissau, University of Copenhagen, Copenhagen, Denmark
    Am J Clin Nutr 86:1376-83. 2007
    ..Little is known regarding vitamin D deficiency (VDD) in African populations and in tuberculosis (TB) patients. VDD has been shown to be associated with TB...
  7. doi request reprint Vitamin D as supplementary treatment for tuberculosis: a double-blind, randomized, placebo-controlled trial
    Christian Wejse
    Infectious Disease Research Unit, Aarhus University Hospital, Skejby, Brendstrupgaardsvej, 8200 Aarhus N, Denmark
    Am J Respir Crit Care Med 179:843-50. 2009
    ..Vitamin D has been shown to be involved in the host immune response toward Mycobacterium tuberculosis...
  8. doi request reprint Urine suPAR levels compared with plasma suPAR levels as predictors of post-consultation mortality risk among individuals assumed to be TB-negative: a prospective cohort study
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau Codex, Guinea Bissau
    Inflammation 33:374-80. 2010
    ..75. For HIV-negative individuals, little or no prognostic effect was observed. However, in both HIV positives and negatives, the predictive effect of U-suPAR was found to be inferior to that of P-suPAR...
  9. doi request reprint The Bandim tuberculosis score: reliability and comparison with the Karnofsky performance score
    Frauke Rudolf
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Scand J Infect Dis 45:256-64. 2013
    ..Our aim was to assess the variability between 2 physicians in performing the Bandim tuberculosis score (TBscore), a clinical severity score for pulmonary TB (PTB), and to compare it to the Karnofsky performance score (KPS)...
  10. pmc Utility of the plasma level of suPAR in monitoring risk of mortality during TB treatment
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    PLoS ONE 7:e43933. 2012
    ..To investigate whether changes in the plasma level of soluble urokinase plasminogen activator receptor (suPAR) can be used to monitor tuberculosis (TB) treatment efficacy...
  11. doi request reprint Differential effects of sex in a West African cohort of HIV-1, HIV-2 and HIV-1/2 dually infected patients: men are worse off
    Sanne Jespersen
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Trop Med Int Health 21:253-62. 2016
    ..We describe differences in baseline characteristics and assess the impact of sex on HIV progression among patients at a clinic with many HIV-2 and HIV-1/2 dually infected patients...
  12. doi request reprint Cohort Profile: The Bissau HIV Cohort-a cohort of HIV-1, HIV-2 and co-infected patients
    Sanne Jespersen
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau, Department of Infectious Diseases, Aarhus University Hospital, Copenhagen, Denmark
    Int J Epidemiol 44:756-63. 2015
    ..The Bissau HIV Cohort is administered by the Bissau HIV Cohort study group. Potential collaborators are invited to contact the chair of the cohort study group, Christian Wejse, e-mail: [wejse@dadlnet.dk].
  13. pmc Lack of awareness of treatment failure among HIV-1-infected patients in Guinea-Bissau - a retrospective cohort study
    Sanne Jespersen
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    J Int AIDS Soc 18:20243. 2015
    ..We assessed CD4 cell counts (as a marker of treatment failure), determined the rate of switching to second-line treatment and evaluated mortality related to treatment failure among HIV-infected patients in Guinea-Bissau...
  14. pmc Challenges facing HIV treatment in Guinea-Bissau: the benefits of international research collaborations
    Sanne Jespersen
    Projecto de Saude de Bandim, INDEPTH Network, Apertado 861, 1004 Bissau Codex, Guinea Bissau
    Bull World Health Organ 92:909-14. 2014
    ..However, substantial problems with the infrastructure for ART delivery remain...
  15. pmc Hepatitis B and Delta virus are prevalent but often subclinical co-infections among HIV infected patients in Guinea-Bissau, West Africa: a cross-sectional study
    Bo Langhoff Hønge
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e99971. 2014
    ..Co or super-infection with hepatitis Delta virus (HDV) may worsen the liver disease and complicate treatment possibilities...
  16. pmc Tuberculosis burden in an urban population: a cross sectional tuberculosis survey from Guinea Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea Bissau
    BMC Infect Dis 10:96. 2010
    ..We conducted a cross sectional survey for pulmonary TB and TB symptoms in Bissau, Guinea-Bissau, in an urban cohort with known HIV prevalence. TB surveillance in the area is routinely based on passive case finding...
  17. ncbi request reprint Assessing factors for loss to follow-up of HIV infected patients in Guinea-Bissau
    Pernille Bejer Nordentoft
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Infection . 2016
    ..The objective of this study was to ascertain vital status of patients considered lost to follow-up at an HIV clinic in Guinea-Bissau, and describe reasons for loss to follow-up (LTFU)...
  18. doi request reprint High mortality risk among individuals assumed to be TB-negative can be predicted using a simple test
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau, West Africa
    Trop Med Int Health 14:986-94. 2009
    ..To determine mortality among assumed TB negative (aTBneg) individuals in Guinea-Bissau and to investigate whether plasma levels of soluble urokinase receptor (suPAR) can be used to determine post-consultation mortality risk...
  19. doi request reprint Nonadherence is Associated with Lack of HIV-Related Knowledge: A Cross-Sectional Study among HIV-Infected Individuals in Guinea-Bissau
    Charlotte Dyrehave
    Bandim Health Project, In depth Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    J Int Assoc Provid AIDS Care 15:350-8. 2016
    ..HIV-related knowledge may affect understanding and utilization of HIV medical information, hence limited health literacy is a known barrier to treatment adherence...
  20. doi request reprint Hepatitis C prevalence among HIV-infected patients in Guinea-Bissau: a descriptive cross-sectional study
    Bo Langhoff Hønge
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej 100, 8200 Aarhus, Denmark Electronic address
    Int J Infect Dis 28:35-40. 2014
    ..To estimate the prevalence and determine the clinical presentation of risk factors of hepatitis C virus (HCV) among HIV-infected patients in Bissau, Guinea-Bissau...
  21. pmc High level of HIV-1 drug resistance among patients with HIV-1 and HIV-1/2 dual infections in Guinea-Bissau
    Sanne Jespersen
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    Virol J 12:41. 2015
    ..The aim of this study was to evaluate levels of HIV-1 resistance among patients with HIV-1 and HIV-1/2 dual infections, treated with ART, at a large HIV clinic in Guinea-Bissau...
  22. doi request reprint TBscore II: refining and validating a simple clinical score for treatment monitoring of patients with pulmonary tuberculosis
    Frauke Rudolf
    From the 1 Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Scand J Infect Dis 45:825-36. 2013
    ..Further, some variables depend on a physician assessing them, making the score less applicable. The aim of the present study was to simplify the TBscore...
  23. pmc Diabetes mellitus and impaired fasting glucose in ART-naïve patients with HIV-1, HIV-2 and HIV-1/2 dual infection in Guinea-Bissau: a cross-sectional study
    Ditte Steiniche
    Bandim Health Project, INDEPTH Network, 1004 Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, 8200 Aarhus N, Denmark
    Trans R Soc Trop Med Hyg 110:219-27. 2016
    ..The prevalence of diabetes mellitus (DM) is expected to increase in sub-Saharan Africa. Patients with HIV are at particular risk. We investigated the DM burden among antiretroviral therapy (ART)-naïve patients with HIV in Guinea-Bissau...
  24. doi request reprint Clinical presentation and opportunistic infections in HIV-1, HIV-2 and HIV-1/2 dual seropositive patients in Guinea-Bissau
    Allan Sørensen
    a Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Infect Dis (Lond) 48:604-11. 2016
    ..Better understanding of HIV-2 infection is likely to affect the patient care in areas where HIV-2 is prevalent. In this study, we aimed to characterize the clinical presentations among HIV-1, HIV-2 and HIV-1/2 dual seropositive patients...
  25. doi request reprint Diabetes mellitus prevalence in tuberculosis patients and the background population in Guinea-Bissau: a disease burden study from the capital Bissau
    Thorny L Haraldsdottir
    Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    Trans R Soc Trop Med Hyg 109:400-7. 2015
    ..Data regarding the association between diabetes mellitus (DM) and tuberculosis (TB) in Africa are scare. We did a DM screening survey among TB patients and non-TB controls in Guinea-Bissau...
  26. doi request reprint Barriers and facilitators to antiretroviral therapy adherence among patients with HIV in Bissau, Guinea-Bissau: A qualitative study
    Dlama N Rasmussen
    a Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea Bissau
    Afr J AIDS Res 12:1-8. 2013
    ..More studies on HIV-related knowledge and adherence among HIV infected individuals are currently needed. ..
  27. doi request reprint Impact of tuberculosis exposure at home on mortality in children under 5 years of age in Guinea-Bissau
    Victor F Gomes
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Thorax 66:163-7. 2011
    ..To assess mortality related to exposure to tuberculosis (TB) at home among children in urban areas of Guinea-Bissau...
  28. doi request reprint Brief Report: Macrophage Activation in HIV-2-Infected Patients Is Less Affected by Antiretroviral Treatment-sCD163 in HIV-1, HIV-2, and HIV-1/2 Dually Infected Patients
    Bo L Hønge
    Department of Clinical Immunology, Aarhus University Hospital, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Departments of Infectious Diseases Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark Department of Biomedicine, Aarhus University, Denmark National HIV Programme, Ministry of Health, Bissau, Guinea Bissau and GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark
    J Acquir Immune Defic Syndr 72:254-8. 2016
    ..145). The larger decrease in sCD163 levels among HIV-1-infected patients during ART may indicate an HIV type-dependent differential effect of ART on macrophage activation during HIV infection. ..
  29. ncbi request reprint Variant mannose-binding lectin alleles are not associated with susceptibility to or outcome of invasive pneumococcal infection in randomly included patients
    Gitte Kronborg
    Department of Infectious Diseases, Rigshospitalet, 2100 Copenhagen, Denmark
    J Infect Dis 185:1517-20. 2002
    ..Thus, in a random adult population with invasive pneumococcal infection, MBL does not seem to play a role in the pathophysiology, in contrast to earlier observations in patients with other concomitant immune abnormalities...
  30. doi request reprint Performance of 3 rapid tests for discrimination between HIV-1 and HIV-2 in Guinea-Bissau, West Africa
    Bo Langhoff Hønge
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau National HIV Programme, Ministry of Health, Bissau, Guinea Bissau National Public Health Laboratory, Bissau, Guinea Bissau GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark and Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
    J Acquir Immune Defic Syndr 65:87-90. 2014
    ..8%), followed by Immunoflow HIV1-HIV2 (agreement 90.9%) and SD Bioline HIV-1/2 3.0 (agreement 84.5%). Our results underscore the need for evaluation of tests in relevant populations before implementation...
  31. doi request reprint Review of cytomegalovirus coinfection in HIV-infected individuals in Africa
    Helene Ladefoged Grønborg
    GloHAU, Department of Public Health, Global Health, Aarhus University, Aarhus N, Denmark
    Rev Med Virol . 2016
    ..Evidence from high-income countries suggests that CMV may alter the outcome of HIV infection, other than causing end-organ diseases. We reviewed literature on HIV and CMV coinfection in Africa...
  32. pmc The when and how of male circumcision and the risk of HIV: a retrospective cross-sectional analysis of two HIV surveys from Guinea-Bissau
    Dlama Nggida Rasmussen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Bissau, Guinea Bissau Department of Infectious Diseases, Odense University Hospital, DK 5000 Odense, Denmark Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK 5000 Odense, Denmark
    Pan Afr Med J 23:21. 2016
    ..Understanding regional variations in circumcision practices and their relationship to HIV is crucial and can increase insight into the HIV epidemic in Africa...
  33. doi request reprint Inter-observer variation of the Bandim TB-score
    Line Raaby
    Infectious Disease Research Unit, Skejby, Aarhus University Hospital, Denmark
    Scand J Infect Dis 41:220-3. 2009
    ..The kappa value of the total Bandim TBscore being at or above 8 points was 0.637, representing a good inter-observer agreement. No systematic bias was found...
  34. ncbi request reprint Effect of sex and age on outcomes among HIV-2-infected patients starting antiretroviral therapy in West Africa
    Boris K Tchounga
    aUniversité Bordeaux, ISPED, Centre INSERM U1219 Epidemiologie Biostatistique, Bordeaux bINSERM, ISPED, Centre INSERM U1219 Epidemiologie Biostatistique, Bordeaux, France cProgramme PACCI, Site de recherche ANRS, Abidjan, Côte d Ivoire dBandim Health Project, INDEPTH Network, Bissau, Guinea Bissau eDepartment of Infectious Diseases fDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark gService des Maladies Infectieuses et Tropicales, CHU de Treichville, Abidjan, Côte d Ivoire hDepartments of Medicine and Global Health, University of Washington, Seattle, Washington, USA iDépartement des Sciences Fondamentales et Santé Publique, Universite de Lome, Lome, Togo See supplemental information for the list of the IeDEA West Africa collaboration members, http links lww com QAD A970
    AIDS 30:2707-2714. 2016
    ..This study aimed to investigate the effect of sex and age on mortality and loss to follow-up (LTFU) among HIV-2-infected individuals initiating ART...
  35. doi request reprint Tuberculosis and hypertension - a systematic review of the literature
    Anneline Borchsenius Seegert
    Medical Student, Aarhus University, Frederiks Alle 75c 2 th, 8000 Aarhus C, Denmark Electronic address
    Int J Infect Dis . 2016
    ..The knowledge about how these diseases influence on each other is not well understood...
  36. doi request reprint Reproductive patterns and fertility wishes among HIV-infected patients: survey from six outpatient clinics in Denmark
    Tinne Laursen
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, Skejby, 8200 Aarhus N, Denmark
    Int J Infect Dis 17:e851-6. 2013
    ..Reproductive patterns among HIV patients in Denmark have not previously been described. We aimed to uncover the fertility wishes among Danish HIV-infected persons...
  37. ncbi request reprint Macrophage serum markers in pneumococcal bacteremia: Prediction of survival by soluble CD163
    Holger Jon Møller
    Department of Clinical Biochemistry, AS Aarhus University Hospital, Denmark
    Crit Care Med 34:2561-6. 2006
    ..This study investigated sCD163 and other markers of macrophage activation (neopterin, ferritin, transcobalamin, and soluble urokinase plasminogen activator receptor [suPAR]) as prognostic factors in patients with pneumococcal bacteremia...
  38. ncbi request reprint Should micronutrient supplementation be integrated into the case management of tuberculosis?
    Christine Stabell Benn
    J Infect Dis 197:1487-9. 2008