E B Schmidt

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi [Marine n-3 polyunsaturated fatty acids and coronary heart disease. Background and status]
    Erik Berg Schmidt
    Arhus Universitetshospital, Aalborg Sygehus, Kardiologisk Afdeling, Lipidklinikken og Kardiovaskulaert Forskningscenter
    Ugeskr Laeger 167:1940-2. 2005
  2. ncbi N-3 fatty acids from fish and coronary artery disease: implications for public health
    E B Schmidt
    Department of Medicine, Hjørring Brønderslev Hospital, Hjørring, Denmark
    Public Health Nutr 3:91-8. 2000
  3. ncbi Marine n-3 polyunsaturated fatty acids and coronary heart disease: Part II. clinical trials and recommendations
    E B Schmidt
    Department of Preventive Cardiology, Aalborg Sygehus, Arhus University Hospitals, Denmark
    Thromb Res 115:257-62. 2005
  4. ncbi Fish, marine n-3 polyunsaturated fatty acids and coronary heart disease: a minireview with focus on clinical trial data
    Erik Berg Schmidt
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus, Arhus University Hospitals, Denmark
    Prostaglandins Leukot Essent Fatty Acids 75:191-5. 2006
  5. ncbi Lipoprotein-associated phospholipase A2 concentrations in plasma are associated with the extent of coronary artery disease and correlate to adipose tissue levels of marine n-3 fatty acids
    Erik Berg Schmidt
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Arhus University Hospitals, Sdr Skovvej 15, 9100 Aalborg, Denmark
    Atherosclerosis 196:420-4. 2008
  6. ncbi Marine n-3 fatty acids: basic features and background
    E B Schmidt
    Department of Medicine Hjorring Bronderslev Sygehus, Denmark
    Lipids 36:S65-8. 2001
  7. ncbi Marine n-3 fatty acids, wine intake, and heart rate variability in patients referred for coronary angiography
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Aalborg, Denmark
    Circulation 103:651-7. 2001
  8. ncbi Flow-mediated vasodilation and dietary intake of n-3 polyunsaturated acids in healthy subjects
    M M Petersen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus Aarhus University Hospital, Soendre Skovvej 15, Aalborg, Aarhus, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:38-44. 2010
  9. doi No effect of high-dose atorvastatin on leukotriene B₄ formation from neutrophils in patients treated with coronary bypass surgery: a randomized placebo-controlled double-blinded trial with a crossover design
    C Lysgaard
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Søndre Skovvej 15, Aalborg 9000, Denmark
    Prostaglandins Leukot Essent Fatty Acids 87:185-8. 2012
  10. ncbi N-3 fatty acids and cardiac autonomic function in humans
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, Moelleparkvej 4, Aalborg, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:131-9. 2010

Collaborators

Detail Information

Publications47

  1. ncbi [Marine n-3 polyunsaturated fatty acids and coronary heart disease. Background and status]
    Erik Berg Schmidt
    Arhus Universitetshospital, Aalborg Sygehus, Kardiologisk Afdeling, Lipidklinikken og Kardiovaskulaert Forskningscenter
    Ugeskr Laeger 167:1940-2. 2005
  2. ncbi N-3 fatty acids from fish and coronary artery disease: implications for public health
    E B Schmidt
    Department of Medicine, Hjørring Brønderslev Hospital, Hjørring, Denmark
    Public Health Nutr 3:91-8. 2000
    ..To review and discuss the effect of n-3 polyunsaturated fatty acids (PUFA) from fish in the prevention and, primarily, in the treatment of coronary artery disease (CAD)...
  3. ncbi Marine n-3 polyunsaturated fatty acids and coronary heart disease: Part II. clinical trials and recommendations
    E B Schmidt
    Department of Preventive Cardiology, Aalborg Sygehus, Arhus University Hospitals, Denmark
    Thromb Res 115:257-62. 2005
  4. ncbi Fish, marine n-3 polyunsaturated fatty acids and coronary heart disease: a minireview with focus on clinical trial data
    Erik Berg Schmidt
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus, Arhus University Hospitals, Denmark
    Prostaglandins Leukot Essent Fatty Acids 75:191-5. 2006
    ..We will not deal with effects of alpha-linolenic acid, the non-marine type of n-3 PUFA derived from plant oils...
  5. ncbi Lipoprotein-associated phospholipase A2 concentrations in plasma are associated with the extent of coronary artery disease and correlate to adipose tissue levels of marine n-3 fatty acids
    Erik Berg Schmidt
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Arhus University Hospitals, Sdr Skovvej 15, 9100 Aalborg, Denmark
    Atherosclerosis 196:420-4. 2008
    ..The results support the view that Lp-PLA(2) may relate to CAD and that intake of marine n-3 fatty acids might reduce plasma Lp-PLA(2) suggesting another mechanism by which n-3 fatty acids could reduce the risk of cardiovascular disease...
  6. ncbi Marine n-3 fatty acids: basic features and background
    E B Schmidt
    Department of Medicine Hjorring Bronderslev Sygehus, Denmark
    Lipids 36:S65-8. 2001
    ..It has therefore been of paramount interest to perform clinical trials. Such evidence and trials are discussed in later chapters, and the results have been very encouraging...
  7. ncbi Marine n-3 fatty acids, wine intake, and heart rate variability in patients referred for coronary angiography
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Aalborg, Denmark
    Circulation 103:651-7. 2001
    ..Dietary n-3 polyunsaturated fatty acids (PUFAs) derived from fish may reduce the incidence of sudden cardiac death (SCD). In addition, wine drinking is suggested to have a protective effect against cardiovascular death...
  8. ncbi Flow-mediated vasodilation and dietary intake of n-3 polyunsaturated acids in healthy subjects
    M M Petersen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus Aarhus University Hospital, Soendre Skovvej 15, Aalborg, Aarhus, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:38-44. 2010
    ..33). In conclusion, our results did not show any correlation between intake and sPL levels of marine n-3 PUFA and FMD in healthy subjects...
  9. doi No effect of high-dose atorvastatin on leukotriene B₄ formation from neutrophils in patients treated with coronary bypass surgery: a randomized placebo-controlled double-blinded trial with a crossover design
    C Lysgaard
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Søndre Skovvej 15, Aalborg 9000, Denmark
    Prostaglandins Leukot Essent Fatty Acids 87:185-8. 2012
    ..Hence, this study does not support any effect of atorvastatin on LTB₄ formation as part of the explanation for its beneficial effect on CVD...
  10. ncbi N-3 fatty acids and cardiac autonomic function in humans
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, Moelleparkvej 4, Aalborg, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:131-9. 2010
    ..Many studies have demonstrated a positive association between cellular content of n-3 PUFA and HRV as well as supplementation with n-3 PUFA seems to increase HRV and thereby decreasing the risk of arrhythmic events and SCD...
  11. ncbi Effects of marine n-3 fatty acids on circulating levels of soluble adhesion molecules in patients with chronic heart failure
    O Eschen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus, Aarhus University Hospital, Aalborg, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:45-51. 2010
    ..The results also indicate that the low dose of n-3 PUFA used in many intervention trials does not have deleterious effects on sCAMs or hsCRP...
  12. ncbi N-3 fatty acids and cardiac function after myocardial infarction in Denmark
    H A Skou
    Department of Medicine, Hjørring Hospital, Denmark
    Int J Circumpolar Health 60:360-5. 2001
    ..Left ventricular function was assessed by transthoracal echo-cardiography and plasma concentration of proANP and N-terminal proANP. No effect of n-3 PUFA could be demonstrated on these indices of left ventricular function...
  13. ncbi Heart rate variability and n-3 polyunsaturated fatty acids in patients with diabetes mellitus
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Aalborg, Denmark
    J Intern Med 249:545-52. 2001
    ..The aim of the present study was to examine associations between n-3 PUFA and 24-h heart rate variability in patients with type 1 and type 2 diabetes mellitus (DM)...
  14. ncbi The effect of n-3 fatty acids on plasma lipids and lipoproteins and blood pressure in patients with CRF
    My Svensson
    Department of Nephrology, Aalborg Hospital, Aalborg, Denmark
    Am J Kidney Dis 44:77-83. 2004
    ..The aim of this study is to examine the effect of n-3 PUFAs on plasma lipid and lipoprotein levels and 24-hour ambulatory BP in patients with CRF...
  15. ncbi Serum concentrations of matrix metalloproteinase-9, tissue inhibitor of matrix metalloproteinase-1 and alpha2-macroglobulin in healthy subjects after supplementation with different doses of marine n-3 fatty acids
    J Vogt
    Department of Cardiology, Aalborg, Aarhus University Hospital, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:102-9. 2010
    ..Marine n-3 polyunsaturated fatty acids (n-3 PUFA) may protect against plaque rupture. The aim was to investigate the effect of marine n-3 PUFA supplementation on serum levels of MMP-9, TIMP-1, and alpha2-macroglobulin...
  16. ncbi Fatty acid composition of the internal mammary artery in relation to dietary intake of marine n-3 polyunsaturated fatty acids and association with flow-mediated vasodilation
    J J Andreasen
    Center for Cardiovascular Research, Aalborg Aarhus University Hospital, Aarhus, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:10-7. 2010
    ..There was no association between FMD and fatty acid composition of the LIMA...
  17. ncbi Heart rate variability and plasma lipids in men with and without ischaemic heart disease
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Denmark
    Atherosclerosis 145:181-6. 1999
    ..In conclusion, the data suggest, that hypercholesterolaemia is associated with a decreased 24-h HRV in men with and without ischaemic heart disease, suggesting an increased risk of sudden cardiac death...
  18. ncbi C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease
    T Madsen
    Department of Cardiology, Aalborg Hospital, Aalborg, Denmark
    Am J Cardiol 88:1139-42. 2001
    ....
  19. ncbi Uric acid in patients with angiographically documented coronary heart disease
    Tonny Studsgaard Petersen
    Department of Preventive Cardiology, Center of Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Acta Cardiol 61:525-9. 2006
    ..We have investigated whether uric acid was an independent risk factor for CHD...
  20. doi The effect of marine n-3 fatty acids in different doses on plasma concentrations of Lp-PLA2 in healthy adults
    Maria Weinkouff Pedersen
    Department of Cardiology and Center for Cardiovascular Research, Aalborg Hospital, Arhus University Hospital, Aalborg, Denmark
    Eur J Nutr 48:1-5. 2009
    ..Lp-PLA(2) can be modified by lipid lowering drugs, but it is unknown whether diet can reduce plasma levels of Lp-PLA(2)...
  21. doi The effect of low-dose marine n-3 fatty acids on the biosynthesis of pro-inflammatory 5-lipoxygenase pathway metabolites in overweight subjects: a randomized controlled trial
    M S Nielsen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Prostaglandins Leukot Essent Fatty Acids 87:43-8. 2012
    ..This study evaluated the effect of n-3 PUFA in a low, but recommended cardioprotective dosage on the formation of 5-lipoxygenase pathway metabolites in overweight subjects...
  22. doi Body composition and body fat distribution in relation to later risk of acute myocardial infarction: a Danish follow-up study
    J G Stegger
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Int J Obes (Lond) 35:1433-41. 2011
    ..We investigated the associations between incident MI and bioelectrical impedance analyses (BIA) derived measures of body composition in combination with body mass index (BMI) and anthropometric measures of body fat distribution...
  23. ncbi The effect of N-3 fatty acids on plasma myeloperoxidase levels in healthy adults
    V L Andersen
    Department of Cardiology, Aalborg Aarhus University Hospital, Aarhus, Denmark
    Cell Mol Biol (Noisy-le-grand) 56:3-9. 2010
    ..To examine the effect of marine n-3 polyunsaturated fatty acids (PUFA) supplementation in a low to moderate and a high dose on plasma levels of myeloperoxidase (MPO) in healthy individuals...
  24. doi Adhesion molecules and C-reactive protein are associated to adverse events in angina pectoris
    Ole Eschen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Sygehus, Aarhus University Hospital, Aalborg, Denmark
    Scand Cardiovasc J 44:153-60. 2010
    ..To examine the prognostic value of soluble cellular adhesion molecules (CAMs) and highly sensitive C reactive protein (hsCRP) on long-term outcome for patients with stable angina pectoris (SAP)...
  25. doi Flow-mediated vasodilatation: variation and interrelationships with plasma lipids and lipoproteins
    Jeppe Grøndahl Rasmussen
    Department of Cardiology, Center for Cardiovascular Research Aalborg Hospital, Arhus University Hospitals, Denmark
    Scand J Clin Lab Invest 69:156-60. 2009
    ..The objective of this study was to examine interrelationships between FMD and plasma lipids and lipoproteins, and to determine the between-operator and within-subject variability associated with this technique...
  26. ncbi HMG-CoA reductase inhibitors improve heart rate variability in patients with a previous myocardial infarction
    Sam Riahi
    Department of Cardiology, Aalborg Hospital, Hobrovej, 9000 Aalborg, Denmark
    Pharmacol Res 45:479-83. 2002
    ..Our data suggest that statins may increase HRV in patients with a previous MI, which could in part explain the early beneficial effect on clinical events observed in several trials...
  27. ncbi Soluble adhesion molecules and marine n-3 fatty acids in patients referred for coronary angiography
    Ole Eschen
    Center for Cardiovascular Research, Department of Cardiology, Aalborg Sygehus, Aarhus University Hospital, Aalborg, Denmark
    Atherosclerosis 180:327-31. 2005
    ..To investigate the relationship between soluble cellular adhesion molecules (sCAMs) and the extent of coronary artery disease (CAD) in patients with stable angina pectoris...
  28. ncbi Heart rate variability is associated with haptoglobin phenotype in patients with coronary artery disease
    Jeppe Hagstrup Christensen
    Department of Nephrology, Aalborg Hospital, Aalborg, Denmark
    Eur J Cardiovasc Prev Rehabil 12:221-5. 2005
    ..Therefore, we hypothesized that the presence of the haptoglobin 1 allele would be associated with a favourable heart rate variability...
  29. ncbi Autonomic nervous system, heart rate variability and n-3 fatty acids
    Jeppe Hagstrup Christensen
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    J Cardiovasc Med (Hagerstown) 8:S19-22. 2007
    ..The modulation of heart rate variability by n-3 PUFAs may partly explain the reduction in sudden cardiac death observed in subjects with a regular intake of n-3 PUFAs...
  30. ncbi Effect of acute changes in oxygen tension on flow-mediated dilation. Relation to cardivascular risk
    Ole Frøbert
    Center for Cardiovascular Research, Department of Cardiology, Aalborg Hospital, and Department of Pharmacology, University of Aarhus, Aalborg, Denmark
    Scand Cardiovasc J 42:38-47. 2008
    ..Oxygen-dependent changes in vascular diameters may be detrimental when the endothelium is dysfunctional...
  31. ncbi Alpha-linolenic acid and heart rate variability in women examined for coronary artery disease
    Jeppe Hagstrup Christensen
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, 9100 Aalborg, Denmark
    Nutr Metab Cardiovasc Dis 15:345-51. 2005
    ..Thus, some limited data suggest an antiarrhythmic effect of ALA. We therefore investigated the association between ALA and 24-h heart rate variability (HRV), a strong predictor of arrhythmic events and sudden cardiac death, in women...
  32. ncbi C-reactive protein is associated with heart rate variability
    Trine Madsen
    Department of Cardiology, and Center for Cardiovascular Research, Aalborg Hospital, Arhus University Hospital, Denmark
    Ann Noninvasive Electrocardiol 12:216-22. 2007
    ..The aim of this study was to investigate the relation between low-grade inflammation and autonomic dysfunction, both of which may be risk markers for sudden cardiac death...
  33. ncbi Statins, ventricular arrhythmias and heart rate variability in patients with implantable cardioverter defibrillators and coronary heart disease
    Sam Riahi
    Department of Cardiology, Cardiovascular Research Center, Aalborg Hospital, Arhus University, Aalborg, Denmark
    Cardiology 104:210-4. 2005
    ..This study lends little support for an antiarrhythmic effect of statins or any relation between plasma lipids and lipoproteins and malignant ventricular arrhythmias in patients with an ICD...
  34. ncbi The effect of atorvastatin on heart rate variability and lipoproteins in patients treated with coronary bypass surgery
    Sam Riahi
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, Arhus University Hospital, Denmark
    Int J Cardiol 111:436-41. 2006
    ..The study therefore does not lend support for any effect of atorvastatin on HRV after 6 weeks of treatment in patients treated with CABG...
  35. ncbi n-3 Fatty acids and ventricular arrhythmias in patients with ischaemic heart disease and implantable cardioverter defibrillators
    Jeppe Hagstrup Christensen
    Department of Nephrology, Aalborg Hospital, Arhus University Hospital, 9100 Aalborg, Denmark
    Europace 7:338-44. 2005
    ..To investigate the relationship between serum content of n-3 polyunsaturated fatty acids (PUFA) and the incidence of ventricular arrhythmias in patients with an implantable cardioverter defibrillator (ICD)...
  36. ncbi Soluble adhesion molecules in healthy subjects: a dose-response study using n-3 fatty acids
    O Eschen
    Department of Cardiology, Aalborg Hospital, Aalborg, Denmark
    Nutr Metab Cardiovasc Dis 14:180-5. 2004
    ....
  37. ncbi n-3 polyunsaturated fatty acids and coronary thrombosis
    S D Kristensen
    Department of Cardiology, Skejby Hospital, Aarhus N, Denmark
    Lipids 36:S79-82. 2001
    ..This does not exclude a beneficial effect of n-3 fatty acids on coronary heart disease as suggested from clinical trials, but the major effect may be antiarrhythmic rather than antithrombotic...
  38. doi Intravenous infusion of n-3 polyunsaturated fatty acids and inducibility of ventricular tachycardia in patients with implantable cardioverter defibrillator
    Trine Madsen
    Department of Cardiology, Center for Cardiovascular Research, Aalborg Hospital, and Department of Health Sciences and Technology, Aalborg University, Hobrovej, Aalborg 9000, Denmark
    Europace 12:941-6. 2010
    ..The aim of this study was to investigate the effect of intravenously administered n-3 PUFA on the inducibility of ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD)...
  39. ncbi Marine n-3 polyunsaturated fatty acids and coronary heart disease. Part I. Background, epidemiology, animal data, effects on risk factors and safety
    Erik Berg Schmidt
    Department of Preventive Cardiology, Aalborg Sygehus, Arhus University Hospitals, Arhus, Denmark
    Thromb Res 115:163-70. 2005
    ..In a forthcoming paper, we will focus on the clinical trial data, current recommendations and suggest trials to further study the role of marine n-3 PUFA in the prevention and treatment of CHD...
  40. ncbi n-3 fatty acids and the risk of sudden cardiac death
    J H Christensen
    Department of Nephrology, Aalborg Hospital, Denmark
    Lipids 36:S115-8. 2001
    ..We have studied the effect of n-3 fatty acids on HRV and present data clearly showing that n-3 fatty acids increase HRV. This adds further to the hypothesis that an increased intake of n-3 fatty acids may reduce the risk of SCD...
  41. ncbi NT-pro-BNP is an independent predictor of mortality in patients with end-stage renal disease
    M Svensson
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, Aarhus, Denmark
    Clin Nephrol 71:380-6. 2009
    ..The aim of the present study was to examine if the level of NT-pro-BNP predicts mortality in patients with ERSD and CVD...
  42. ncbi N-3 fatty acids as secondary prevention against cardiovascular events in patients who undergo chronic hemodialysis: a randomized, placebo-controlled intervention trial
    My Svensson
    Department of Nephrology, Aalborg Hospital, Aarhus University Hospital, Hobrovej 18 20, 9100 Aalborg, Denmark
    Clin J Am Soc Nephrol 1:780-6. 2006
    ..N-3 PUFA significantly reduced the number of myocardial infarctions as a secondary outcome, a finding that might be of clinical interest...
  43. ncbi n-3 fatty acids in the treatment of diabetic patients: biological rationale and clinical data
    Raffaele De Caterina
    Institute of Cardiology, G D Annunzio University, Chieti, Italy
    Diabetes Care 30:1012-26. 2007
  44. doi Effect of the administration of n-3 polyunsaturated fatty acids on circulating levels of microparticles in patients with a previous myocardial infarction
    Serena Del Turco
    CNR Institute of Clinical Physiology, Pisa, Italy
    Haematologica 93:892-9. 2008
    ....
  45. ncbi Letter regarding article by Mozaffarian et al, "fish intake and risk of incident atrial fibrillation"
    Jeppe Hagstrup Christensen
    Circulation 111:e37; author reply e37. 2005
  46. ncbi Marine n-3 fatty acids and thrombosis
    Erik Berg Schmidt
    Thromb Res 111:9-10. 2003
  47. ncbi [Alcohol and lifestyle diseases]
    Kjeld Hermansen
    Motions og Ernaeringsrådet, Søborg
    Ugeskr Laeger 169:3404-6. 2007
    ..No clear association is found between alcohol and obesity. In contrast, alcohol intake is associated with increased risk of various cancers, e.g. a linear increased risk of breast cancer with every unit of alcohol is present...