Cathrine Ørskov

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 119:151-4. 2004
  2. ncbi GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 124:105-12. 2005
  3. ncbi The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist
    Jesper Thulesen
    Department of Medical Anatomy, Section B, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 N, Copenhagen, Denmark
    Regul Pept 103:9-15. 2002
  4. ncbi Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1
    Randi Ugleholdt
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Endocrinology 145:1349-55. 2004
  5. doi The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
    Jens Pedersen
    Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, DK 2200 Copenhagen, Denmark
    Peptides 67:20-8. 2015
  6. doi Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
    Peter Johannes Holst
    Department of International Health, University of Copenhagen, Copenhagen, Denmark
    J Immunol 184:4431-9. 2010
  7. ncbi Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs
    Carl Frederik Nagell
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark
    Scand J Gastroenterol 41:667-72. 2006
  8. pmc Metformin stimulates FGF21 expression in primary hepatocytes
    Eva B Nygaard
    Department of Pharmacology and Pharmacotherapy, University of Copenhagen, 2100 Copenhagen, Denmark
    Exp Diabetes Res 2012:465282. 2012

Collaborators

Detail Information

Publications8

  1. ncbi Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 119:151-4. 2004
    ..Thus, the aim of this study was to study the occurrence of genetic variants in the GIP and GLP-1 encoding regions of the proGIP and proglucagon genes in type 2 diabetic patients and matched control subjects...
  2. ncbi GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 124:105-12. 2005
    ..Glucagon-like peptide-2 is thought to act as a growth factor for the gut, but the localization of the GLP-2 receptor and mechanism of action on epithelial growth is unclear...
  3. ncbi The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist
    Jesper Thulesen
    Department of Medical Anatomy, Section B, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 N, Copenhagen, Denmark
    Regul Pept 103:9-15. 2002
    ..Consistent with the observed in vivo activities, our functional studies and binding data indicate that GLP-2 (3-33) acts as a partial agonist with potential competitive antagonistic properties on the GLP-2 receptor...
  4. ncbi Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1
    Randi Ugleholdt
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Endocrinology 145:1349-55. 2004
    ..These findings strongly suggest that PC1 is essential for intestinal proglucagon processing in vivo and, thereby, plays an important role in production of the incretin hormone GLP-1 and the intestinotrophic hormone GLP-2...
  5. doi The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
    Jens Pedersen
    Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, DK 2200 Copenhagen, Denmark
    Peptides 67:20-8. 2015
    ..Our findings provide evidence for the expression of the GLP-2R in intestinal compartments rich in enteric neurons and, importantly they exclude significant expression in the epithelium of rat jejunal mucosa. ..
  6. doi Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
    Peter Johannes Holst
    Department of International Health, University of Copenhagen, Copenhagen, Denmark
    J Immunol 184:4431-9. 2010
    ..These findings indicate that the localization of the adenoviral inoculum and not the total Ag load determines the quality of the CD8(+) T cell response induced with adenoviral vaccines...
  7. ncbi Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs
    Carl Frederik Nagell
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark
    Scand J Gastroenterol 41:667-72. 2006
    ....
  8. pmc Metformin stimulates FGF21 expression in primary hepatocytes
    Eva B Nygaard
    Department of Pharmacology and Pharmacotherapy, University of Copenhagen, 2100 Copenhagen, Denmark
    Exp Diabetes Res 2012:465282. 2012
    ..As FGF21 therapy normalizes blood glucose in animal models of type 2 diabetes, the induction of hepatic FGF21 by metformin might play an important role in metformin's antidiabetic effect...