Carsten Roepstorff

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects
    Carsten Roepstorff
    Department of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, DK 2100 Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 282:E435-47. 2002
  2. ncbi Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 291:E1106-14. 2006
  3. pmc Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
    J Physiol 574:125-38. 2006
  4. ncbi Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, Universitetsparken 13, DK 2100 Ø, Denmark
    Am J Physiol Endocrinol Metab 287:E696-705. 2004
  5. pmc Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Physiol 560:551-62. 2004
  6. ncbi Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 288:E133-42. 2005
  7. ncbi Regulation of oxidative enzyme activity and eukaryotic elongation factor 2 in human skeletal muscle: influence of gender and exercise
    C Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Acta Physiol Scand 184:215-24. 2005
  8. doi Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle
    Christian Frøsig
    Copenhagen Muscle Research Centre, Molecular Physiology Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    Am J Physiol Endocrinol Metab 296:E787-95. 2009
  9. doi Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling
    Louise Høeg
    The Copenhagen Muscle Research Centre, Molecular Physiology Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    J Appl Physiol (1985) 107:824-31. 2009
  10. ncbi Myocellular triacylglycerol breakdown in females but not in males during exercise
    Charlotte H Steffensen
    Department of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, DK 2100 Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 282:E634-42. 2002

Detail Information

Publications16

  1. ncbi Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects
    Carsten Roepstorff
    Department of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, DK 2100 Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 282:E435-47. 2002
    ..However, an effect of gender appears to occur in the utilization of the different lipid sources...
  2. ncbi Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 291:E1106-14. 2006
    ..The higher basal IMTG content in women compared with men is therefore the best candidate to explain the higher IMTG net hydrolysis during exercise in women...
  3. pmc Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
    J Physiol 574:125-38. 2006
    ....
  4. ncbi Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, Universitetsparken 13, DK 2100 Ø, Denmark
    Am J Physiol Endocrinol Metab 287:E696-705. 2004
    ..Rather, the latter seems to be limited by intracellular regulatory mechanisms...
  5. pmc Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Physiol 560:551-62. 2004
    ..Apparently, HSL Ser565 phosphorylation by AMPK during exercise had no effect on HSL activity. Alternatively, other factors including ERK may have counterbalanced any effect of AMPK on HSL activity...
  6. ncbi Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 288:E133-42. 2005
    ..They also suggest that, with high muscle glycogen, the availability of free carnitine may limit fat oxidation during exercise, due to its increased use for acetylcarnitine formation...
  7. ncbi Regulation of oxidative enzyme activity and eukaryotic elongation factor 2 in human skeletal muscle: influence of gender and exercise
    C Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Acta Physiol Scand 184:215-24. 2005
    ..To investigate gender-related differences in the responses of oxidative enzymes and eukaryotic elongation factor-2 (eEF2) to exercise...
  8. doi Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle
    Christian Frøsig
    Copenhagen Muscle Research Centre, Molecular Physiology Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    Am J Physiol Endocrinol Metab 296:E787-95. 2009
    ..Collectively, this study indicates that reduced muscle MCoA content in recovery from exercise may be part of the adaptive response leading to improved insulin action on glucose uptake after exercise in human muscle...
  9. doi Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling
    Louise Høeg
    The Copenhagen Muscle Research Centre, Molecular Physiology Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    J Appl Physiol (1985) 107:824-31. 2009
    ..This was not explained by sex differences in proximal insulin signaling in women. In women, it seems that a high capillary density and type 1 muscle fiber expression may be important for insulin action...
  10. ncbi Myocellular triacylglycerol breakdown in females but not in males during exercise
    Charlotte H Steffensen
    Department of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, DK 2100 Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 282:E634-42. 2002
    ..MCTG use was correlated to the resting concentration of MCTG (P < 0.001). We conclude that resting content and use of MCTG during exercise are related to gender and furthermore are independent of training status...
  11. ncbi Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender
    Bente Kiens
    Department of Human Physiology, The Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Appl Physiol (1985) 97:1209-18. 2004
    ....
  12. ncbi Intramuscular triacylglycerol in energy metabolism during exercise in humans
    Carsten Roepstorff
    The Copenhagen Muscle Research Centre, Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
    Exerc Sport Sci Rev 33:182-8. 2005
    ..It is important to consider how measurements of IMTG have been performed. Hormone-sensitive lipase is thought to regulate breakdown of IMTG during exercise...
  13. ncbi Sarcolemmal FAT/CD36 in human skeletal muscle colocalizes with caveolin-3 and is more abundant in type 1 than in type 2 fibers
    Bodil Vistisen
    Copenhagen Muscle Research Centre, Department of Medical Anatomy, University of Copenhagen, Copenhagen, Denmark
    J Lipid Res 45:603-9. 2004
    ..Furthermore, we provide evidence that FAT/CD36 expression is significantly higher in type 1 compared with type 2 fibers, whereas caveolin-3 expression is significantly higher in type 2 fibers than in type 1 fibers...
  14. pmc Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle
    Christian Frøsig
    Copenhagen Muscle Research Centre, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, 13, Universitetsparken, DK 2100, Copenhagen, Denmark
    J Physiol 582:1289-301. 2007
    ..Furthermore, endurance exercise increased the responsiveness of aPKC to PIP3 providing a possible link to improved insulin-stimulated glucose uptake after exercise...
  15. ncbi Effect of sex differences on human MEF2 regulation during endurance exercise
    Kristian Vissing
    Department of Sports Science, University of Aarhus, Dalgas Avenue 4, Aarhus C, Denmark
    Am J Physiol Endocrinol Metab 294:E408-15. 2008
    ..This signaling response was independent of sex...
  16. pmc Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation
    Johan W E Jocken
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Diabetes 57:1834-41. 2008
    ..We aimed to investigate whether a blunted fasting or beta-adrenergically mediated lipolysis contributes to this increased IMTG storage in obesity...