University of Southern Denmark

Summary

Organization: University of Southern Denmark
Country: Denmark

Top Publications

  1. pmc Lipid-lowering treatment to the end? A review of observational studies and RCTs on cholesterol and mortality in 80+-year olds
    Line Kirkeby Petersen
    Research Unit of Epidemiology, Danish Aging Research Center, University of Southern Denmark, Odense, Denmark
    Age Ageing 39:674-80. 2010
  2. ncbi Influence of endotoxin-induced sepsis on the requirements of propofol-fentanyl infusion rate in pigs
    Peter J A Bollen
    Biomedical Laboratory, University of Southern Denmark, Odense, Denmark
    Basic Clin Pharmacol Toxicol 101:192-6. 2007
  3. ncbi Use of desmopressin in elderly patients in Denmark
    Torbjörn Callréus
    Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Pharmacoepidemiol Drug Saf 16:995-8. 2007
  4. ncbi Relationships between objective and perceived housing in very old age
    Carita Nygren
    Research Unit of Occupational Therapy, Institute of Public Health, University of Southern Denmark, Winsløws vej 9B 5000, Odense C, Denmark
    Gerontologist 47:85-95. 2007
  5. ncbi Animal models of human placentation--a review
    A M Carter
    Department of Physiology and Pharmacology, University of Southern Denmark, Winsloewparken 21, Third Floor, DK 5000 Odense, Denmark
    Placenta 28:S41-7. 2007
  6. ncbi Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice
    K L Lambertsen
    Medical Biotechnology Center, Winsloewparken 25, University of Southern Denmark, Odense, DK 5000, Denmark
    Neuroscience 144:934-49. 2007
  7. ncbi Early exposure to smoking and future fecundity among Danish twins
    T K Jensen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Int J Androl 29:603-13. 2006
  8. ncbi Osteoblast differentiation of NIH3T3 fibroblasts is associated with changes in the IGF-I/IGFBP expression pattern
    Basem M Abdallah
    Department of Biochemistry, Faculty of Science, Helwan University, Cairo, Egypt
    Cell Mol Biol Lett 11:461-74. 2006
  9. ncbi Does persistent involvement by the GP improve palliative care at home for end-stage cancer patients?
    Birgit Aabom
    Research Unit for General Practice, University of Southern Denmark, J B Winsloøws Vej 9A, 5000 Odense C, Denmark
    Palliat Med 20:507-12. 2006
  10. ncbi Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup
    Jesper L Boldsen
    Institute of Forensic Medicine, Department of Anthropology, ADBOU, University of Southern Denmark, DK 5230 Odense M, Denmark
    Am J Phys Anthropol 132:59-66. 2007

Research Grants

  1. Gene-enviornment interactions in facial clefts
    Kaare Christensen; Fiscal Year: 2006

Detail Information

Publications62

  1. pmc Lipid-lowering treatment to the end? A review of observational studies and RCTs on cholesterol and mortality in 80+-year olds
    Line Kirkeby Petersen
    Research Unit of Epidemiology, Danish Aging Research Center, University of Southern Denmark, Odense, Denmark
    Age Ageing 39:674-80. 2010
    ....
  2. ncbi Influence of endotoxin-induced sepsis on the requirements of propofol-fentanyl infusion rate in pigs
    Peter J A Bollen
    Biomedical Laboratory, University of Southern Denmark, Odense, Denmark
    Basic Clin Pharmacol Toxicol 101:192-6. 2007
    ..In the present study, we adjusted the level of anaesthesia according to clinical signs, and found good agreement with CSI...
  3. ncbi Use of desmopressin in elderly patients in Denmark
    Torbjörn Callréus
    Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Pharmacoepidemiol Drug Saf 16:995-8. 2007
    ..Against the background of the approval of the use of desmopressin in the treatment of nocturia in adults, the aim of the present study was to describe patterns of its use in elderly patients in Denmark from 2000 to 2004...
  4. ncbi Relationships between objective and perceived housing in very old age
    Carita Nygren
    Research Unit of Occupational Therapy, Institute of Public Health, University of Southern Denmark, Winsløws vej 9B 5000, Odense C, Denmark
    Gerontologist 47:85-95. 2007
    ..Our purpose in this study was to explore relationships between aspects of objective and perceived housing in five European samples of very old adults, as well as to investigate whether cross-national comparable patterns exist...
  5. ncbi Animal models of human placentation--a review
    A M Carter
    Department of Physiology and Pharmacology, University of Southern Denmark, Winsloewparken 21, Third Floor, DK 5000 Odense, Denmark
    Placenta 28:S41-7. 2007
    ..Models that are likely to be established in the wake of comparative genomics include the marmoset, tree shrew, hedgehog tenrec and nine-banded armadillo...
  6. ncbi Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice
    K L Lambertsen
    Medical Biotechnology Center, Winsloewparken 25, University of Southern Denmark, Odense, DK 5000, Denmark
    Neuroscience 144:934-49. 2007
    ..The data show that increased expression of the TNF-p75 receptor following induction of focal cerebral ischemia in mice can be attributed to expression in activated microglial cells and blood-borne macrophages...
  7. ncbi Early exposure to smoking and future fecundity among Danish twins
    T K Jensen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Int J Androl 29:603-13. 2006
    ..65; 95% CI 0.47-0.91). This study supports that smoking is hazardous to the female fetus not only in the short term but also affects her future ability to conceive and makes it even more important to advise pregnant women to stop smoking...
  8. ncbi Osteoblast differentiation of NIH3T3 fibroblasts is associated with changes in the IGF-I/IGFBP expression pattern
    Basem M Abdallah
    Department of Biochemistry, Faculty of Science, Helwan University, Cairo, Egypt
    Cell Mol Biol Lett 11:461-74. 2006
    ..Modulation of the IGF/IGFBP levels by glucocorticoid might suggest important roles for the IGF-system in mediating the osteoblast differentiation of the NIH3T3 cell line...
  9. ncbi Does persistent involvement by the GP improve palliative care at home for end-stage cancer patients?
    Birgit Aabom
    Research Unit for General Practice, University of Southern Denmark, J B Winsloøws Vej 9A, 5000 Odense C, Denmark
    Palliat Med 20:507-12. 2006
    ..To analyse the effect of GP home visits on the granting of a terminal declaration (TD) and on place of death...
  10. ncbi Early childhood stress and adult age mortality--a study of dental enamel hypoplasia in the medieval Danish village of Tirup
    Jesper L Boldsen
    Institute of Forensic Medicine, Department of Anthropology, ADBOU, University of Southern Denmark, DK 5230 Odense M, Denmark
    Am J Phys Anthropol 132:59-66. 2007
    ..The values of the case fatality rates for young children might be slightly biased upward because of a higher than average number of older children and adolescents dying with LEH...
  11. ncbi Exercise intervention of 65+-year-old men and women: functional ability and health care costs
    Sonja Vestergaard
    Centre of Applied and Clinical Exercise Sciences, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, 5230 Odense M, Denmark
    Aging Clin Exp Res 18:227-34. 2006
    ..The aim of this study was to evaluate: i) the effect of a PAP on functional ability and the use of health care services; ii) the possible association between level of functional ability and public health care costs...
  12. ncbi [Back pain]
    Tom Bendix
    Syddansk Universitet, RygForskningsCentret, Clinical Locomotion Science og Rygcenter Fyn
    Ugeskr Laeger 168:1954-7. 2006
    ..Subgroup identification is a central issue in modern research, because the effect of treatment can be very different across such groups...
  13. ncbi Danish version of the Oswestry disability index for patients with low back pain. Part 2: Sensitivity, specificity and clinically significant improvement in two low back pain populations
    Henrik Hein Lauridsen
    Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    Eur Spine J 15:1717-28. 2006
    ....
  14. ncbi [Vitamin D1alpha-hydroxylase deficiency as the cause of severe rickets in a 1-year-old-old boy]
    Signe Sparre Beck-Nielsen
    Odense Universitetshospital, Børneafdelingen
    Ugeskr Laeger 168:700-2. 2006
    ..The treatment was changed to an activated formula of vitamin D, alphacalcidol, whereupon the clinical and biochemical symptoms rapidly improved...
  15. ncbi Sources for comparative studies of placentation I. embryological collections
    A M Carter
    Physiology and Pharmacology, University of Southern Denmark, J B Winsloewvej 21, DK 5000 Odense, Denmark
    Placenta 29:95-8. 2008
    ..Included are some of the major series of human and animal embryos, such as the Boyd and Carnegie collections, as these also house placental material...
  16. doi Pain in the back and neck are with us until the end: a nationwide interview-based survey of Danish 100-year-olds
    Jan Hartvigsen
    Clinical Locomotion Science, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Campusvej, Odense M, Denmark
    Spine (Phila Pa 1976) 33:909-13. 2008
    ..Nationwide interview survey...
  17. pmc Unit-specific calibration of Actigraph accelerometers in a mechanical setup - is it worth the effort? The effect on random output variation caused by technical inter-instrument variability in the laboratory and in the field
    Niels C Moeller
    Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    BMC Med Res Methodol 8:19. 2008
    ..Therefore, the primary aim of this study was to calculate and apply unit-specific calibration factors in multiple accelerometers in order to examine the impact on random output variation caused by inter-instrument variability...
  18. doi Renal cortical and medullary blood flow responses to altered NO availability in humans
    Mads Damkjær
    Institute of Molecular Medicine, Univ of Southern Denmark, 21 J B Winsloews Vej, DK 5000 Odense, Denmark
    Am J Physiol Regul Integr Comp Physiol 299:R1449-55. 2010
    ..The technique seems to provide indices of renal medullary blood flow in humans...
  19. doi Endothelial dysfunction and blood pressure alterations in K+-channel transgenic mice
    Ralf Köhler
    Renal and Cardiovascular Research, Institute of Molecular Medicine, University of Southern Denmark, J B Winsløwsvej 21 3, 5000, Odense, Denmark
    Pflugers Arch 459:969-76. 2010
    ..These alterations strengthen the perspective that vascular K(+) channels are potential pharmacologic targets for improvement of vasodilator functions in cardiovascular pathologies...
  20. pmc Neck pain and anxiety do not always go together
    Corrie Myburgh
    University of Southern Denmark, Institute of Clinical Biomechanics, Campusvej 55, Odense M, 5230, Denmark
    Chiropr Osteopat 18:6. 2010
    ..More studies are needed to clarify the specific role of anxiety in chronic non-specific musculoskeletal pain before general evidence-driven clinical extrapolations can be made...
  21. doi Congenital hydrocephalus--prevalence, prenatal diagnosis and outcome of pregnancy in four European regions
    Ester Garne
    Paediatric Department, Kolding Hospital, DK 6000 Kolding, Denmark
    Eur J Paediatr Neurol 14:150-5. 2010
    ..To describe prevalence, prenatal diagnosis and outcome for fetuses and infants with congenital hydrocephalus...
  22. doi Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia
    Maria Montero Domínguez
    Department of Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Winslowparken 21, DK 5000 Odense C, Denmark
    Exp Neurol 218:11-23. 2009
    ....
  23. ncbi [Drug marketing: methods, effect and regulation]
    Jens Søndergaard
    Forskningsenheden for Almen Medicin, Institut for Sundhedstjenesteforskning, Syddansk Universitet, DK 5000 Odense C
    Ugeskr Laeger 171:778-80. 2009
    ..It has been shown that this interaction influences physicians' prescriptions inappropriately. As the interaction is inevitable, it should be further addressed how this interaction may be regulated to minimize non-rational prescribing...
  24. ncbi Movement detection impaired in patients with knee osteoarthritis compared to healthy controls: a cross-sectional case-control study
    H Lund
    Research Initiative for Physiotherapy, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    J Musculoskelet Neuronal Interact 8:391-400. 2008
    ..This indicates that OA may be associated with a generalized defect in proprioception with possible implications for the pathogenesis of the joint degeneration...
  25. doi Incidence and prevalence of nutritional and hereditary rickets in southern Denmark
    Signe Sparre Beck-Nielsen
    Department of Pediatrics, Hospital of Southwest Denmark, Esbjerg, Denmark
    Eur J Endocrinol 160:491-7. 2009
    ..To estimate the incidence of nutritional rickets and the incidence and prevalence of hereditary rickets...
  26. pmc Power for genetic association study of human longevity using the case-control design
    Qihua Tan
    Department of Biochemistry, Pharmacology and Genetics, Odense University Hospital, Sdr Boulevard 29, DK 5000 Odense C, Denmark
    Am J Epidemiol 168:890-6. 2008
    ..Power is drastically reduced when nonagenarians are considered cases, with a more than 5-fold difference in the size of the case sample required to achieve comparable power as that found with centenarians...
  27. pmc Cohort changes in cognitive function among Danish centenarians. A comparative study of 2 birth cohorts born in 1895 and 1905
    Henriette Engberg
    Danish Aging Research Center, Epidemiology Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Dement Geriatr Cogn Disord 26:153-60. 2008
    ..The objective was to examine cohort changes in cognitive function in 2 cohorts of centenarians born 10 years apart...
  28. pmc Communicating effectiveness of intervention for chronic diseases: what single format can replace comprehensive information?
    Henrik Stovring
    Research Unit for General Practice, University of Southern Denmark, Odense, Denmark
    BMC Med Inform Decis Mak 8:25. 2008
    ..Hence we study the concordance of decisions based on one of four single information formats for treatment effectiveness with subsequent decisions based on all four formats combined with a pictorial representation...
  29. pmc Differential and correlation analyses of microarray gene expression data in the CEPH Utah families
    Qihua Tan
    Department of Biochemistry, Pharmacology, and Genetics, Odense University Hospital, Denmark
    Genomics 92:94-100. 2008
    ..In addition, we observe an interesting pattern of sibship correlation on gene expression that increases exponentially with the mean of gene expression reflecting the enhanced genetic control over the functionally active genes...
  30. doi Supplementation with orange and blackcurrant juice, but not vitamin E, improves inflammatory markers in patients with peripheral arterial disease
    Christine Dalgård
    Research Unit of Biochemistry, Pharmacology and Genetics, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
    Br J Nutr 101:263-9. 2009
    ..In this study, orange and blackcurrant juice reduced markers of inflammation, but not markers of endothelial activation, in patients with peripheral arterial disease, relative to sugar drinks...
  31. ncbi Mini review: physical activity and fitness and its relations to cardiovascular disease risk factors in children
    K Froberg
    Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    Int J Obes (Lond) 29:S34-9. 2005
    ..This paper aim to review the newest literature linking physical inactivity and low fitness to metabolic disorders including cardiovascular disease (CVD) risk factors and obesity...
  32. ncbi General practitioners choose within a narrow range of drugs when initiating new treatments: a cohort study of cardiovascular drug formularies
    Allan Buusman
    Research Unit of General Practice, University of Southern Denmark, J B Winsløws Vej 9, 5000 Odense C, Denmark
    Eur J Clin Pharmacol 61:651-6. 2005
    ....
  33. ncbi Rising prevalence of diabetes: evidence from a Danish pharmaco-epidemiological database
    Henrik Støvring
    Research Unit of General Practice, University of Southern Denmark, DK 5000, Odense, Denmark
    Lancet 362:537-8. 2003
    ..Future research into the causes of rising diabetes prevalence should take this fall in mortality into account to avoid incorrect conclusions about the relation between western lifestyle and the growing number of diabetics...
  34. ncbi Biological variation in variables associated with exercise training
    M Bagger
    Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Main Campus Odense University, Denmark
    Int J Sports Med 24:433-40. 2003
    ..8 %). The low critical difference and variation within subjects of the psychological and in particular the performance and physiological variables indicate that they may be beneficial as primary markers of training induced changes...
  35. ncbi Cancer occurrence among radiation workers at Jaslovské Bohunice nuclear power plant
    G Gulis
    University of Southern Denmark, Department of Health Promotion Research, Institute of Public Health, Niels Bohrvej 9 10, 6700 Esbjerg, Denmark
    Cent Eur J Public Health 11:91-7. 2003
    ..The estimated excess risks in both approaches and both for mortality and morbidity study were rather anecdotal due to lack of statistical significance caused by small number of cases...
  36. ncbi Low-dose indinavir in combination with low-dose ritonavir: steady-state pharmacokinetics and long-term clinical outcome follow-up
    U S Justesen
    Institute of Public Health, Clinical Pharmacology, University of Southern Denmark, Odense
    HIV Med 4:250-4. 2003
    ..To evaluate the long-term efficacy and pharmacokinetics of indinavir (IDV)/ritonavir (RTV) 400/100 mg twice a day in combination with two nucleoside reverse transcriptase inhibitors...
  37. ncbi Attenuated growth of breast-fed children exposed to increased concentrations of methylmercury and polychlorinated biphenyls
    Philippe Grandjean
    Department of Environmental Health, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA
    FASEB J 17:699-701. 2003
    ..Thus, in communities with increased contaminant exposures, risks associated with lactational transfer of toxicants to the infant must be considered when judging the benefits of prolonged breast-feeding...
  38. ncbi [Do children of long-lived parents age more successfully?]
    Henrik Frederiksen
    Institut for Sundhedstjenesteforskning, Epidemiologi, Syddansk Universitet, 5000 Odense C
    Ugeskr Laeger 164:5027-32. 2002
    ..Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful ageing. The children of long-lived parents may therefore age more successfully than the children of short-lived parents...
  39. ncbi Perception of risk information. Similarities and differences between Danish and Polish general practitioners
    Jørgen Nexøe
    Research Unit of General Practice, University of Southern Denmark, Odense
    Scand J Prim Health Care 20:183-7. 2002
    ..The objective of the study was to gain better insight into how general practitioners (GPs) perceive risk reduction and the way this perception may be influenced by healthcare environment...
  40. ncbi Do children of long-lived parents age more successfully?
    Henrik Frederiksen
    Institute of Public Health, Epidemiology, University of Southern Denmark, Odense
    Epidemiology 13:334-9. 2002
    ..Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful aging. The children of long-lived parents may therefore age more successfully than the children of short-lived parents...
  41. ncbi Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures
    B W Kristensen
    Anatomy and Neurobiology, Inst of Medical Biology, SDU Odense University, Winsløwparken 21, DK 5000 Odense C, Denmark
    Brain Res 917:21-44. 2001
    ....
  42. ncbi Evaluation of two putative susceptibility loci for oral clefts in the Danish population
    L E Mitchell
    Department of Biostatistics, and Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Epidemiol 153:1007-15. 2001
    ..However, there is no evidence that the risk of CL+/-P or CP is influenced by gene-environment interactions involving MSX1 or TGFB3 and either first trimester exposure to maternal cigarette smoke or alcohol consumption...
  43. ncbi Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries
    E Garne
    Eurocat Registry of Funen County, University of Southern Denmark, Denmark
    Ultrasound Obstet Gynecol 17:386-91. 2001
    ..To evaluate prenatal diagnosis of congenital heart diseases by ultrasound investigation in well-defined European populations...
  44. ncbi Genetic and environmental factors in epilepsy: a population-based study of 11900 Danish twin pairs
    M J Kjeldsen
    Department of Neurology, Odense University Hospital, Odense, Denmark
    Epilepsy Res 44:167-78. 2001
    ..In conclusion, this study has confirmed the substantial impact, which genetic factors have in the etiology of epilepsy. The heritability of epilepsy is high and seems to increase with age...
  45. ncbi Dementia is not inevitable: a population-based study of Danish centenarians
    K Andersen-Ranberg
    Aging Research Centre, University of Southern Denmark, Odense University, Odense, Denmark
    J Gerontol B Psychol Sci Soc Sci 56:P152-9. 2001
    ..Dementia is common but not inevitable in centenarians. Cerebro- and cardiovascular diseases are equally common in demented and nondemented persons...
  46. ncbi A clinical study comparing PureSperm and SpermFilter for density gradient separation of human spermatozoa in assisted reproduction
    Steen B Laursen
    Fertility Clinic, Odense University Hospital, Copenhagen, Denmark
    Acta Obstet Gynecol Scand 82:929-35. 2003
    ..To compare a new density gradient medium, SpermFilter, for purifying spermatozoa in assisted reproduction with the more established medium, PureSperm...
  47. ncbi Exposure to potential drug interactions in primary health care
    Lars Bjerrum
    Research Unit of General Practice, University of Southern Denmark, Odense
    Scand J Prim Health Care 21:153-8. 2003
    ..To analyse the prevalence of potential drug interactions, and to identify patients particularly prone to drug interaction...
  48. ncbi Differences in health complaints among university students from three European countries
    C Stock
    School of Public Health, University of Bielefeld, Germany
    Prev Med 37:535-43. 2003
    ..The purpose of this research was to assess the prevalence of somatic and psychosomatic health complaints in a cross-national population of university students and to study risk factors associated with health complaints...
  49. ncbi Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair
    Jens Noraberg
    Anatomy and Neurobiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Curr Drug Targets CNS Neurol Disord 4:435-52. 2005
    ....
  50. ncbi The epidemic of type 2 diabetes is a statistical artefact
    A Green
    Department of Applied Research and Health Technology Assessment, Odense University Hospital, Denmark
    Diabetologia 48:1456-8. 2005
  51. ncbi Percutaneous penetration through slightly damaged skin
    Jesper B Nielsen
    Environmental Medicine, University of Southern Denmark, Winsløwparken 17, 5000, Odense C, Denmark
    Arch Dermatol Res 296:560-7. 2005
    ..The percutaneous penetration of the most hydrophilic compounds will be those most affected. These findings should be considered when setting standards for dermal exposure to chemicals...
  52. ncbi Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells
    Jorge S Burns
    Department of Endocrinology and Metabolism and Institute of Pathology, Odense University Hospital, Medical Biotechnology Center, Winsløwparken 25, DK 5000 Odense C, Denmark
    Cancer Res 65:3126-35. 2005
    ..Thus, hMSC-TERT20 clones represent cancer stem cells with hierarchical tumorigenicity, providing new models to explore the stem cell hypothesis for cancer...
  53. ncbi [Need of and searching for information by patients with acute myeloid leukemia undergoing intensive therapy]
    Lone Smidstrup Friis
    Syddansk Universitet, Almen Medicin, Institut for Sundhedstjenesteforskning
    Ugeskr Laeger 167:514-6. 2005
  54. ncbi Counter-current transfer in reproductive biology
    N Einer-Jensen
    Institute of Medical Biology, University of Southern Denmark, Odense, Denmark and Institute of Reproduction, Royal Veterinary and Agricultural University, Copenhagen, Denmark
    Reproduction 129:9-18. 2005
    ..Counter-current transfer of drugs after local application opens up new possibilities for treatment...
  55. ncbi Early discontinuation of antidepressants in general practice: association with patient and prescriber characteristics
    Dorte Gilså Hansen
    Research Unit of General Practice, University of Southern Denmark, Odense, Denmark
    Fam Pract 21:623-9. 2004
    ..Discontinuation may, however, be caused by a complexity of factors, but so far research has focused on drug effects, adverse effects and drug regimens...
  56. ncbi Secondary effects induced by the colon carcinogen azoxymethane in BDIX rats
    Morten Kobaek-Larsen
    Biomedical Laboratory, University of Southern Denmark, Odense, Denmark
    APMIS 112:319-29. 2004
    ..This may therefore be strain related. In order to reduce the secondary effects of the induction of colon cancer by AOM, it is advisable to use male rats only and a maximum latency period of 32 weeks...
  57. ncbi Leprosy and mortality in the Medieval Danish village of Tirup
    Jesper L Boldsen
    Institute of Forensic Medicine, Department of Anthropology, ADBOU, SDU Odense University, DK 5000 Odense C, Denmark
    Am J Phys Anthropol 126:159-68. 2005
    ..The association between lambda and dental enamel hypoplasia indicates a relationship between stress in early childhood (ages 1-6 years) and subsequent development of signs of leprosy...
  58. ncbi Health status of people of slums in Nairobi, Kenya
    Gabriel Gulis
    Department of Health Promotion Research, Institute of Public Health, University of Southern Denmark, Niels Bohrvej 9 10, Esbjerg 6700, Denmark
    Environ Res 96:219-27. 2004
    ..This fact should be taken into account when planning future relief programs...
  59. ncbi Modest implication of interleukin-6 promoter polymorphisms in longevity
    L Christiansen
    Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Mech Ageing Dev 125:391-5. 2004
    ..We found a modest, but significant, increase in the frequency of interleukin-6 -174GG homozygotes with age suggesting that this genotype is advantageous for longevity...
  60. ncbi Rifampicin seems to act as both an inducer and an inhibitor of the metabolism of repaglinide
    Tanja Busk Bidstrup
    Odense University Hospital and Clinical Pharmacology, University of Southern Denmark, Winsløwparken 192, 5000 Odense C, Denmark
    Eur J Clin Pharmacol 60:109-14. 2004
    ..To investigate if rifampicin is both an inducer and an inhibitor of repaglinide metabolism, it was determined whether the timing of rifampicin co-administration influences the pharmacokinetics of repaglinide...
  61. pmc The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes
    Robert Graham Quinton Leslie
    Department of Immunology and Microbiology, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
    Immunology 111:86-90. 2004
    ..A model accounting for the effectiveness of the AP in both preserving C3 fragment integrity and initiating MAC is presented...
  62. ncbi Effects of four detergents on the in-vitro barrier function of human skin
    J B Nielsen
    Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Int J Occup Environ Health 6:143-7. 2000
    ..The present experimental approach allows discrimination between detergents that act through different mechanisms to enhance percutaneous penetration...

Research Grants4

  1. Gene-enviornment interactions in facial clefts
    Kaare Christensen; Fiscal Year: 2006
    ..This study will provide a new level of understanding for a complex birth defect trait. ..