Julian Macoveanu

Summary

Affiliation: Copenhagen University Hospital
Country: Denmark

Publications

  1. doi request reprint Effects of selective serotonin reuptake inhibition on neural activity related to risky decisions and monetary rewards in healthy males
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark Electronic address
    Neuroimage 99:434-42. 2014
  2. doi request reprint Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Kettegaard Alle 30, Hvidovre DK 2650, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark Electronic address
    Brain Res 1556:19-27. 2014
  3. pmc Serotonin 2A receptors contribute to the regulation of risk-averse decisions
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark Electronic address
    Neuroimage 83:35-44. 2013
  4. pmc Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Eur Neuropsychopharmacol 23:919-30. 2013
  5. doi request reprint Effects of Erythropoietin on Hippocampal Volume and Memory in Mood Disorders
    Kamilla W Miskowiak
    Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Electronic address
    Biol Psychiatry 78:270-7. 2015
  6. pmc Serotonin 2A receptors, citalopram and tryptophan-depletion: a multimodal imaging study of their interactions during response inhibition
    Julian Macoveanu
    Danish Research Centre for MR, Copenhagen University Hospital, Hvidovre, Denmark
    Neuropsychopharmacology 38:996-1005. 2013
  7. ncbi request reprint Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use
    Helle Ruff Laursen
    Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
    J Psychopharmacol 30:1296-1304. 2016
  8. pmc Acute serotonin 2A receptor blocking alters the processing of fearful faces in the orbitofrontal cortex and amygdala
    Bettina Hornboll
    1Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
    J Psychopharmacol 27:903-14. 2013
  9. doi request reprint Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks
    Cheryl L Grady
    Rotman Research Institute at Baycrest, University of Toronto, Toronto, Canada
    Eur Neuropsychopharmacol 23:368-78. 2013
  10. doi request reprint Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Psychiatric Center Copenhagen, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Electronic address
    Neuroimage 139:37-43. 2016

Collaborators

Detail Information

Publications14

  1. doi request reprint Effects of selective serotonin reuptake inhibition on neural activity related to risky decisions and monetary rewards in healthy males
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark Electronic address
    Neuroimage 99:434-42. 2014
    ..The data suggest that prolonged SSRI treatment might reduce emotional engagement by reducing the impact of risk during decision-making or the impact of reward during outcome evaluation...
  2. doi request reprint Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Kettegaard Alle 30, Hvidovre DK 2650, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark Electronic address
    Brain Res 1556:19-27. 2014
    ..Given the unique profile of action of each serotonergic receptor subtype, future pharmacological studies may favor receptor specific investigations to complement present research mainly focused on global serotonergic manipulations. ..
  3. pmc Serotonin 2A receptors contribute to the regulation of risk-averse decisions
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark Electronic address
    Neuroimage 83:35-44. 2013
    ..These results have implications for understanding the neural basis of abnormal risk-taking behavior, for instance in pathological gamblers. ..
  4. pmc Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Eur Neuropsychopharmacol 23:919-30. 2013
    ....
  5. doi request reprint Effects of Erythropoietin on Hippocampal Volume and Memory in Mood Disorders
    Kamilla W Miskowiak
    Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Electronic address
    Biol Psychiatry 78:270-7. 2015
    ..Erythropoietin (EPO) increases neuroplasticity and reduces cognitive difficulties in treatment-resistant depression (TRD) and remitted BD. This magnetic resonance imaging study assessed the neuroanatomical basis for these effects...
  6. pmc Serotonin 2A receptors, citalopram and tryptophan-depletion: a multimodal imaging study of their interactions during response inhibition
    Julian Macoveanu
    Danish Research Centre for MR, Copenhagen University Hospital, Hvidovre, Denmark
    Neuropsychopharmacology 38:996-1005. 2013
    ..These links between serotonergic function and response inhibition in healthy subjects may help to interpret serotonergic abnormalities underlying impulsivity in neuropsychiatric disorders...
  7. ncbi request reprint Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use
    Helle Ruff Laursen
    Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
    J Psychopharmacol 30:1296-1304. 2016
    ..These results indicate that the effects of long-term serotonin depletion resulting from ecstasy use are dose-dependent, affecting the functional neural basis of emotional face processing...
  8. pmc Acute serotonin 2A receptor blocking alters the processing of fearful faces in the orbitofrontal cortex and amygdala
    Bettina Hornboll
    1Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
    J Psychopharmacol 27:903-14. 2013
    ..To elucidate its role in processing of fear and anger, healthy individuals were studied with functional magnetic resonance imaging (fMRI) after 5-HT2A receptor blockade, while judging the gender of neutral, fearful and angry faces...
  9. doi request reprint Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks
    Cheryl L Grady
    Rotman Research Institute at Baycrest, University of Toronto, Toronto, Canada
    Eur Neuropsychopharmacol 23:368-78. 2013
    ..Lower serotonin leads to a broadening of a normally fear-specific response to anger, and higher levels reduce the differentiated brain response to aversive face emotions...
  10. doi request reprint Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Psychiatric Center Copenhagen, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Electronic address
    Neuroimage 139:37-43. 2016
    ..The findings provide converging evidence that risk processing is sensitive to bright-light exposure during winter...
  11. pmc Sex-Steroid Hormone Manipulation Reduces Brain Response to Reward
    Julian Macoveanu
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neuropsychopharmacology 41:1057-65. 2016
    ..Abnormal reward processing may constitute a neurobiological mechanism by which sex-steroid fluctuations provoke mood disorders in susceptible women. ..
  12. pmc Healthy co-twins of patients with affective disorders show reduced risk-related activation of the insula during a monetary gambling task
    Julian Macoveanu
    From the Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Macoveanu, Siebner the Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Macoveanu the Psychiatric Centre Copenhagen, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark Macoveanu, Miskowiak, Kessing, Vinberg and the Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark Siebner
    J Psychiatry Neurosci 41:38-47. 2016
    ..However, value-based decision making is not well understood in these at-risk individuals...
  13. doi request reprint The Center for Integrated Molecular Brain Imaging (Cimbi) database
    Gitte M Knudsen
    Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Rigshospitalet, DK 2100 Copenhagen, Denmark Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, DK 2100 Copenhagen, Denmark Faculty of Health and Medical Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark Electronic address
    Neuroimage 124:1213-9. 2016
    ..g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank. ..
  14. pmc Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder
    Kamilla W Miskowiak
    Clinic for Affective Disorders, Department of Psychiatry, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Trials 11:97. 2010
    ....