Bjørn H Ebdrup

Summary

Affiliation: Center for Neuropsychiatric Schizophrenia Research
Country: Denmark

Publications

  1. ncbi request reprint [White matter alterations in schizophrenia]
    Bjørn H Ebdrup
    Center for Neuropsykiatrisk Skizofreniforskning CNSR and CINS, Psykiatrisk Center Glostrup, Nordre Ringvej 67, 2600 Glostrup
    Ugeskr Laeger 176:. 2014
  2. pmc Volumetric changes in the basal ganglia after antipsychotic monotherapy: a systematic review
    B H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research, CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Psychiatric Center Glostrup, University Hospital DK Glostrup, Denmark
    Curr Med Chem 20:438-47. 2013
  3. pmc Glucagon-like peptide-1 analogs against antipsychotic-induced weight gain: potential physiological benefits
    Bjørn H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research, CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Psychiatric Center Glostrup, University of Copenhagen, DK 2600 Glostrup, Denmark
    BMC Med 10:92. 2012
  4. pmc Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia
    Bjørn H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Psychiatric Center Glostrup, Copenhagen University Hospital, Glostrup, Denmark
    J Psychiatry Neurosci 35:95-104. 2010
  5. ncbi request reprint [Patients with first-episode psychosis should not be scanned routinely]
    Bjørn H Ebdrup
    Center for Neuropsykiatrisk Skizofreniforskning CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research CINS, Psykiatrisk Center Glostrup, 2600 Glostrup, Denmark
    Ugeskr Laeger 173:484-9. 2011
  6. doi request reprint Progressive striatal and hippocampal volume loss in initially antipsychotic-naive, first-episode schizophrenia patients treated with quetiapine: relationship to dose and symptoms
    Bjørn H Ebdrup
    Centre for Neuropsychiatric Schizophrenia Research, CNSR, Psychiatric Centre Glostrup, Copenhagen University Hospital, Glostrup, Denmark
    Int J Neuropsychopharmacol 14:69-82. 2011
  7. doi request reprint Neural markers of negative symptom outcomes in distributed working memory brain activity of antipsychotic-naive schizophrenia patients
    Ayna B Nejad
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Int J Neuropsychopharmacol 16:1195-204. 2013
  8. pmc Frontal D2/3 Receptor Availability in Schizophrenia Patients Before and After Their First Antipsychotic Treatment: Relation to Cognitive Functions and Psychopathology
    Henrik Nørbak-Emig
    Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Mental Health Centre Glostrup, Mental Health Services, Capital Region of Denmark, Glostrup, Denmark Drs Nørbak Emig, Ebdrup, Fagerlund, Rasmussen, and Glenthøj University of Copenhagen, Faculty of Health and Medical Sciences, Department of Clinical Medicine, Copenhagen, Denmark Drs Nørbak Emig and Glenthøj Neurobiology Research Unit and Epilepsy Clinic, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Drs Svarer and Pinborg Department of Education, Centre for Research in Compulsory Schooling, Aarhus University, Denmark Dr Allerup Functional Imaging Unit, Department of Diagnostics, Copenhagen University Hospital, Glostrup Hospital, Denmark Dr Rostrup Department of Clinical Physiology and Nuclear Medicine, Copenhagen University, Bispebjerg Hospital, Denmark Dr Friberg
    Int J Neuropsychopharmacol 19:. 2016
  9. doi request reprint Effect of GLP-1 receptor agonist treatment on body weight in obese antipsychotic-treated patients with schizophrenia: a randomized, placebo-controlled trial
    Pelle L Ishøy
    Center for Neuropsychiatric Schizophrenia Research, CNSR, and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Mental Health Centre Glostrup, University of Copenhagen, Glostrup, Denmark
    Diabetes Obes Metab . 2016
  10. pmc Structural brain correlates of sensorimotor gating in antipsychotic-naive men with first-episode schizophrenia
    Trine Bjørg Hammer
    Center for Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Glostrup, Denmark
    J Psychiatry Neurosci 38:34-42. 2013

Collaborators

Detail Information

Publications19

  1. ncbi request reprint [White matter alterations in schizophrenia]
    Bjørn H Ebdrup
    Center for Neuropsykiatrisk Skizofreniforskning CNSR and CINS, Psykiatrisk Center Glostrup, Nordre Ringvej 67, 2600 Glostrup
    Ugeskr Laeger 176:. 2014
    ..To dissect potential medication effects from myelination deficits related to symptoms, longitudinal studies in initially antipsychotic-naive first-episode patients with schizophrenia are needed. ..
  2. pmc Volumetric changes in the basal ganglia after antipsychotic monotherapy: a systematic review
    B H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research, CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Psychiatric Center Glostrup, University Hospital DK Glostrup, Denmark
    Curr Med Chem 20:438-47. 2013
    ....
  3. pmc Glucagon-like peptide-1 analogs against antipsychotic-induced weight gain: potential physiological benefits
    Bjørn H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research, CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Psychiatric Center Glostrup, University of Copenhagen, DK 2600 Glostrup, Denmark
    BMC Med 10:92. 2012
    ..Moreover, we account for similarities in brain changes between schizophrenia and overweight patients...
  4. pmc Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia
    Bjørn H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Psychiatric Center Glostrup, Copenhagen University Hospital, Glostrup, Denmark
    J Psychiatry Neurosci 35:95-104. 2010
    ..In this study, we examined whether ventricular enlargement and hippocampal and caudate volume reductions are morphological traits of antipsychotic-naive first-episode schizophrenia...
  5. ncbi request reprint [Patients with first-episode psychosis should not be scanned routinely]
    Bjørn H Ebdrup
    Center for Neuropsykiatrisk Skizofreniforskning CNSR and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research CINS, Psykiatrisk Center Glostrup, 2600 Glostrup, Denmark
    Ugeskr Laeger 173:484-9. 2011
    ..We concluded that there is no evidence in support of performing routine CT scans of first-episode psychotic patients. If intracranial pathology is suspected clinically, an MRI scan should be performed...
  6. doi request reprint Progressive striatal and hippocampal volume loss in initially antipsychotic-naive, first-episode schizophrenia patients treated with quetiapine: relationship to dose and symptoms
    Bjørn H Ebdrup
    Centre for Neuropsychiatric Schizophrenia Research, CNSR, Psychiatric Centre Glostrup, Copenhagen University Hospital, Glostrup, Denmark
    Int J Neuropsychopharmacol 14:69-82. 2011
    ..The mechanisms underlying progressive brain changes, specific antipsychotic compounds and clinical symptoms warrant further research...
  7. doi request reprint Neural markers of negative symptom outcomes in distributed working memory brain activity of antipsychotic-naive schizophrenia patients
    Ayna B Nejad
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Int J Neuropsychopharmacol 16:1195-204. 2013
    ..This information may be used to stratify patients into subgroups thereby facilitating personalized treatment...
  8. pmc Frontal D2/3 Receptor Availability in Schizophrenia Patients Before and After Their First Antipsychotic Treatment: Relation to Cognitive Functions and Psychopathology
    Henrik Nørbak-Emig
    Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Mental Health Centre Glostrup, Mental Health Services, Capital Region of Denmark, Glostrup, Denmark Drs Nørbak Emig, Ebdrup, Fagerlund, Rasmussen, and Glenthøj University of Copenhagen, Faculty of Health and Medical Sciences, Department of Clinical Medicine, Copenhagen, Denmark Drs Nørbak Emig and Glenthøj Neurobiology Research Unit and Epilepsy Clinic, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Drs Svarer and Pinborg Department of Education, Centre for Research in Compulsory Schooling, Aarhus University, Denmark Dr Allerup Functional Imaging Unit, Department of Diagnostics, Copenhagen University Hospital, Glostrup Hospital, Denmark Dr Rostrup Department of Clinical Physiology and Nuclear Medicine, Copenhagen University, Bispebjerg Hospital, Denmark Dr Friberg
    Int J Neuropsychopharmacol 19:. 2016
    ..Here, we examined the effect of dopamine D2/3 receptor blockade on cognition. Additionally, we explored the relation between frontal D2/3 receptor availability and treatment effect on positive symptoms...
  9. doi request reprint Effect of GLP-1 receptor agonist treatment on body weight in obese antipsychotic-treated patients with schizophrenia: a randomized, placebo-controlled trial
    Pelle L Ishøy
    Center for Neuropsychiatric Schizophrenia Research, CNSR, and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Mental Health Centre Glostrup, University of Copenhagen, Glostrup, Denmark
    Diabetes Obes Metab . 2016
    ..We investigated metabolic effects of the GLP-1RA, exenatide once-weekly, in non-diabetic, antipsychotic-treated, obese patients with schizophrenia...
  10. pmc Structural brain correlates of sensorimotor gating in antipsychotic-naive men with first-episode schizophrenia
    Trine Bjørg Hammer
    Center for Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Glostrup, Denmark
    J Psychiatry Neurosci 38:34-42. 2013
    ..Our aim was to examine the structural brain correlates of PPI in antipsychotic-naive patients with first-episode schizophrenia...
  11. ncbi request reprint Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment
    Henrik Nørbak-Emig
    a Centre for Neuropsychiatric Schizophrenia Research, CNSR and Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Mental Health Centre, Glostrup, University of Copenhagen, Denmark
    World J Biol Psychiatry . 2016
    ....
  12. pmc Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist--protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study: the TAO study protocol
    Pelle L Ishøy
    Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Psychiatric Center Glostrup, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark
    BMJ Open 4:e004158. 2014
    ..Secondary endpoints include physiological and metabolic measurements, various psychopathological and cognitive measures, and structural and functional brain MRI...
  13. doi request reprint Serotonin 2A receptor antagonists for treatment of schizophrenia
    Bjørn H Ebdrup
    Center for Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital Glostrup, Faculty of Health Sciences, Psychiatric Center Glostrup, Nordre Ringvej 29, DK 2600 Glostrup, Denmark
    Expert Opin Investig Drugs 20:1211-23. 2011
    ..It is, therefore, of paramount importance to identify new treatment strategies for schizophrenia...
  14. pmc Frontal fasciculi and psychotic symptoms in antipsychotic-naive patients with schizophrenia before and after 6 weeks of selective dopamine D2/3 receptor blockade
    Bjørn H Ebdrup
    From the Centre for Neuropsychiatric Schizophrenia Research, CNSR and Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Copenhagen University Hospital, Mental Health Centre Ebdrup, Raghava, Nielsen, Glenthøj and the Functional Imaging Unit, Department of Diagnostics, Glostrup University Hospital Raghava, Rostrup, Glostrup, Denmark
    J Psychiatry Neurosci 41:133-41. 2016
    ....
  15. doi request reprint Postprandial prolactin suppression appears absent in antipsychotic-treated male patients
    Klara Coello
    Centre for Neuropsychiatric Schizophrenia Research, CNSR, Psychiatric Centre Glostrup, Copenhagen University Hospitals, Mental Health Services, Capital Region of Denmark, Glostrup, Denmark Psychiatric Centre Copenhagen, Department O, Copenhagen University Hospitals, Mental Health Services, Capital Region of Denmark, Copenhagen, Denmark
    Psychoneuroendocrinology 60:1-6. 2015
    ..Antipsychotics and hyperprolactinemia are both considered risk factors of metabolic disturbances and diabetes. Investigations on prolactin response to meal ingestion in antipsychotic-treated patients are missing...
  16. pmc Brain connectivity studies in schizophrenia: unravelling the effects of antipsychotics
    Ayna B Nejad
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Psychiatric Center Glostrup, Denmark
    Curr Neuropharmacol 10:219-30. 2012
    ..We conclude with a discussion of possible avenues for further investigation...
  17. doi request reprint Striatal Reward Activity and Antipsychotic-Associated Weight Change in Patients With Schizophrenia Undergoing Initial Treatment
    Mette Ø Nielsen
    Centre for Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, University of Copenhagen, Copenhagen, Denmark2Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, University of Cop
    JAMA Psychiatry 73:121-8. 2016
    ..Weight gain is a common and serious adverse effect of antipsychotic treatment. A variable individual predisposition to development of metabolic disturbances calls for predictive biological markers...
  18. doi request reprint Neocortical serotonin2A receptor binding predicts quetiapine associated weight gain in antipsychotic-naive first-episode schizophrenia patients
    Hans Rasmussen
    Faculty of Health Sciences, Centre for Neuropsychiatric Schizophrenia Research and Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Psychiatric Centre Glostrup, Copenhagen University Hospital Glostrup, Denmark
    Int J Neuropsychopharmacol 17:1729-36. 2014
    ....
  19. doi request reprint Impaired temporoparietal deactivation with working memory load in antipsychotic-naïve patients with first-episode schizophrenia
    Ayna B Nejad
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    World J Biol Psychiatry 12:271-81. 2011
    ..Using fMRI, we tested whether antipsychotic-naïve schizophrenia patients were impaired at deactivating brain regions that do not subserve WM...