Hans Jurgen Hoffmann

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. pmc Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
    Claus Uhrenholt Christensen
    Allergy Center for West Denmark, Aarhus University Hospital, Aarhus, Denmark Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark
    Ann Dermatol 25:522-3. 2013
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
  3. doi request reprint Cultured human mast cells are heterogeneous for expression of the high-affinity IgE receptor FcεRI
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University and Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 157:246-50. 2012
  4. pmc Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
    Susan Mikkelsen
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Clin Mol Allergy 8:2. 2010
  5. doi request reprint Human skin keratins are the major proteins in exhaled breath condensate
    H J Hoffmann
    Dept of Respiratory Diseases, Aarhus University Hospital, Denmark
    Eur Respir J 31:380-4. 2008
  6. doi request reprint Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations
    Inge Kortekaas Krohn
    Department of Respiratory Medicine, Aarhus University Hospital, Aarhus, Denmark
    J Asthma 50:117-21. 2013
  7. doi request reprint Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells
    Hanne Busk Andersen
    Department of Paediatrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    J Immunol Methods 336:166-74. 2008
  8. doi request reprint Seven week culture of functional human mast cells from buffy coat preparations
    Mette Holm
    Department of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Immunol Methods 336:213-21. 2008
  9. pmc Lysis with Saponin improves detection of the response through CD203c and CD63 in the basophil activation test after crosslinking of the high affinity IgE receptor FcepsilonRI
    Hans Jurgen Hoffmann
    Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus University, DK 8000 Aarhus C, Denmark
    Clin Mol Allergy 3:10. 2005
  10. pmc Intralymphatic immunotherapy induces allergen specific plasmablasts and increases tolerance to skin prick testing in a pilot study
    Johannes Martin Schmid
    Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
    Clin Transl Allergy 6:19. 2016

Collaborators

  • Ronald Dahl
  • Christine Dahl
  • Mette Holm
  • Martin Raithel
  • Johannes Martin Schmid
  • Claus Uhrenholt Christensen
  • Inge Kortekaas Krohn
  • Nikolaos G Papadopoulos
  • Peter Oluf Schiøtz
  • Susan Mikkelsen
  • Susan Hansen
  • Hanne Busk Andersen
  • Hans Henrik Torp Madsen
  • Peter Adler Würtzen
  • Homaira Nezam
  • Alexander Schmitz
  • Gitte Lund
  • Christian Vestergaard
  • Pernille Munk Frandsen
  • Radoslaw Spiewak
  • Gianni Pala
  • Jean Luc Fauquert
  • Lilit Hovhannisyan
  • Paraskevi Xepapadaki
  • Clare Mills
  • Filippo Fassio
  • Sven Seys
  • Beatrice M Bilò
  • George Konstantinou
  • Jacques Gayraud
  • Frode L Jahnsen
  • Markus Ollert
  • Eckard Hamelmann
  • Peter Schmid-Grendelmeier
  • Peter W Hellings
  • Liam O'Mahony
  • Marcin Kurowski
  • Ewa Cichocka-Jarosz
  • Victoria Cardona
  • Marek Jutel
  • Bodo Niggemann
  • Santiago Quirce
  • Rodrigo Rodrigues Alves
  • Constantinos Pitsios
  • Gunter Sturm
  • Svetlana Sergejeva
  • Ines Swoboda
  • Valerie Hox
  • Antoine Magnan
  • Javier Fernandez
  • Nikolaos Douladiris
  • Moises Calderon
  • Antonella Muraro
  • Jörg Kleine-Tebbe
  • Cansin Sackesen
  • Gianenrico Senna
  • Susanne Lau
  • Paraskevi Mangina
  • Roger Lauener
  • Benno Schnyder
  • Annalisa Santucci
  • Indre Butiene
  • Philippe Gevaert
  • Lars Olaf Cardell
  • Aline Sprikkelman
  • Stefano Del Giacco
  • Claudia Traidl-Hoffmann
  • Jan Lotvall
  • Edward Knol
  • Lars K Poulsen
  • Ayse Fusun Kalpaklioglu
  • Cemal Cingi
  • Karin Hoffmann-Sommergruber
  • Alberto Papi
  • Jeroen Buters
  • Clive Grattan
  • Francois Spertini
  • Peter Burney
  • Nicolette Dejong
  • Berber Vlieg-Boerstra
  • Onur Boyman
  • Elina Toskala
  • Zeljka Roje
  • Ewa Bogacka
  • Ervinç Mingomataj
  • Mariana Couto
  • Cezmi A Akdis
  • Alexandra F Santos
  • Matteo Bonini
  • Marta Ferrer

Detail Information

Publications16

  1. pmc Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
    Claus Uhrenholt Christensen
    Allergy Center for West Denmark, Aarhus University Hospital, Aarhus, Denmark Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus, Denmark
    Ann Dermatol 25:522-3. 2013
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
    ..Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein...
  3. doi request reprint Cultured human mast cells are heterogeneous for expression of the high-affinity IgE receptor FcεRI
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University and Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 157:246-50. 2012
    ..We determined the density of FcεRI on mast cells cultured from cord (CBMC) and peripheral blood (PBMC) and studied the kinetics of the response through FcεRI...
  4. pmc Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
    Susan Mikkelsen
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Clin Mol Allergy 8:2. 2010
    ..Expression of CD203c was compared to CD63 as marker for basophil activation, using a Bland Altman plot and ROC curves...
  5. doi request reprint Human skin keratins are the major proteins in exhaled breath condensate
    H J Hoffmann
    Dept of Respiratory Diseases, Aarhus University Hospital, Denmark
    Eur Respir J 31:380-4. 2008
    ..Filtration of inspired air did not remove contaminating keratin. In conclusion, skin keratin in exhaled breath condensate derives from ambient air and not from the respiratory tract...
  6. doi request reprint Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations
    Inge Kortekaas Krohn
    Department of Respiratory Medicine, Aarhus University Hospital, Aarhus, Denmark
    J Asthma 50:117-21. 2013
    ..This study extends the dependence of effector cell degranulation on IgE concentration to mast cells cultured with IgE for 2 weeks...
  7. doi request reprint Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells
    Hanne Busk Andersen
    Department of Paediatrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    J Immunol Methods 336:166-74. 2008
    ..Cord and peripheral blood may give rise to different types of MC. The question addressed should determine the progenitor cell and protocol to be used...
  8. doi request reprint Seven week culture of functional human mast cells from buffy coat preparations
    Mette Holm
    Department of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
    J Immunol Methods 336:213-21. 2008
    ..g. bone marrow or cord blood-derived progenitors. Consequently, our protocol has great potential in studies on mast cell biology and mast cell pathology, and e.g. on evaluation of drug effects...
  9. pmc Lysis with Saponin improves detection of the response through CD203c and CD63 in the basophil activation test after crosslinking of the high affinity IgE receptor FcepsilonRI
    Hans Jurgen Hoffmann
    Department of Pulmonary Medicine, Aarhus University Hospital, Aarhus University, DK 8000 Aarhus C, Denmark
    Clin Mol Allergy 3:10. 2005
    ....
  10. pmc Intralymphatic immunotherapy induces allergen specific plasmablasts and increases tolerance to skin prick testing in a pilot study
    Johannes Martin Schmid
    Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
    Clin Transl Allergy 6:19. 2016
    ..ILIT deposits allergen in an inguinal lymph node to elicit a strong immune stimulus. This allowed us to monitor appearance of allergen specific plasmablasts 7 days after allergen injection...
  11. doi request reprint Pretreatment IgE sensitization patterns determine the molecular profile of the IgG4 response during updosing of subcutaneous immunotherapy with timothy grass pollen extract
    Johannes Martin Schmid
    Departments of Respiratory Medicine and Allergy, Aarhus University Hospital, Aarhus, Denmark
    J Allergy Clin Immunol 137:562-70. 2016
    ..Allergen immunotherapy is an effective treatment of allergic rhinoconjunctivitis. Clinical efficacy is associated with improvement of basophil sensitivity and an increase in allergen-specific immunoglobulin concentration...
  12. doi request reprint Asthmatics able to step down from inhaled corticosteroid treatment without loss of asthma control have low serum eotaxin/CCL11
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Arhus University Hospital, Denmark
    Clin Respir J 2:149-57. 2008
    ..The addition of a long-acting beta2 agonist (LABA) to inhaled corticosteroid (ICS) may control asthma better than ICS alone. Eosinophil markers may predict symptom severity in asthma...
  13. doi request reprint Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard
    Susan Hansen
    Department of Respiratory Diseases, Aarhus University and Hospital, DK 8000 Aarhus C, Denmark
    J Immunol Methods 338:58-62. 2008
    ..CVA with PanLeukoGating can be established using microscopy as a reference, and is comparable to BT chamber and SPT determination. Leukocyte concentrations can be measured with CVA on flow cytometers in research and clinical settings...
  14. ncbi request reprint Response of respiratory flour allergics in an ingested flour challenge may involve plasmacytoid dendritic cells, CD25+ and CD152+ T cells
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
    Int Arch Allergy Immunol 140:252-60. 2006
    ..A number of occupational respiratory allergens are food related, and little is known about the responses these allergens elicit in sensitized persons that ingest them...
  15. ncbi request reprint A single exposure to organic dust of non-naïve non-exposed volunteers induces long-lasting symptoms of endotoxin tolerance
    Hans Jurgen Hoffmann
    Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Germany
    Int Arch Allergy Immunol 138:121-6. 2005
    ..Endotoxin tolerance has previously been described in vitro and animal studies as a mechanism that modifies the threshold at which response occurs...
  16. ncbi request reprint Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin
    H J Hoffmann
    Institute of Medical Biochemistry, Aarhus University, Denmark
    J Invest Dermatol 103:370-5. 1994
    ..56) to levels that resemble those observed in unfractionated keratinocyte populations obtained from normal skin...