Fenghua Chen

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. doi request reprint Mitochondrial plasticity of the hippocampus in a genetic rat model of depression after antidepressant treatment
    Fenghua Chen
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Synapse 67:127-34. 2013
  2. doi request reprint Changes in rat hippocampal CA1 synapses following imipramine treatment
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory and MIND Center, Aarhus University, DK 8000 Aarhus C, Denmark
    Hippocampus 18:631-9. 2008
  3. doi request reprint Repeated electroconvulsive seizures increase the total number of synapses in adult male rat hippocampus
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory and MIND Center, Aarhus University, Aarhus C, Denmark
    Eur Neuropsychopharmacol 19:329-38. 2009
  4. doi request reprint Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory, Danish Neuroscience Centre, Aarhus Sygehus, Aarhus University Hospital, Noerrebrogade 44, DK 8000 Aarhus C, Denmark
    Hippocampus 20:1376-84. 2010
  5. pmc Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase
    Nicoletta Nava
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, Aarhus, Denmark Drs Nava, Chen, and Nyengaard Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Risskov, Denmark Drs Nava, Treccani, Liebenberg, Chen, and Wegener Pharmaceutical Research Center of Excellence, School of Pharmacy, North West University, Potchefstroom, South Africa Dr Wegener Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari and Center of Excellence on Neurodegenerative Diseases, Universita degli Studi di Milano, Milano, Italy Drs Treccani and Popoli
    Int J Neuropsychopharmacol 18:. 2014
  6. doi request reprint Quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression
    Susanne S Kaae
    Stereology and EM Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Synapse 66:667-76. 2012
  7. doi request reprint Vortioxetine promotes early changes in dendritic morphology compared to fluoxetine in rat hippocampus
    Fenghua Chen
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, DK 8240 Risskov, Denmark Electronic address
    Eur Neuropsychopharmacol 26:234-45. 2016
  8. doi request reprint A new efficient method for synaptic vesicle quantification reveals differences between medial prefrontal cortex perforated and nonperforated synapses
    Nicoletta Nava
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, 8000, Aarhus C, Denmark Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, 8240, Risskov, Denmark
    J Comp Neurol 522:284-97. 2014
  9. doi request reprint Ultrastructure and mitochondrial numbers in pre- and postpubertal pig oocytes
    Hanne Skovsgaard Pedersen
    Department of Animal Science, Aarhus University, Blichers alle 20, DK 8830 Tjele, Denmark
    Reprod Fertil Dev 28:586-98. 2016

Collaborators

  • Gregers Wegener
  • Connie Sanchez
  • Nicoletta Nava
  • Jens Randel Nyengaard
  • Hanne Skovsgaard Pedersen
  • Maurizio Popoli
  • Susanne S Kaae
  • Poul Hyttel
  • Henrik Callesen
  • Nanett Kvist Nikolaisen
  • Peter Holm
  • Peter Løvendahl
  • Nico Liebenberg
  • Giulia Treccani
  • Torsten M Madsen
  • Jens R Nyengaard

Detail Information

Publications9

  1. doi request reprint Mitochondrial plasticity of the hippocampus in a genetic rat model of depression after antidepressant treatment
    Fenghua Chen
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Synapse 67:127-34. 2013
    ..Moreover, the changes in mitochondrial morphology and number are a consistent feature of neuroplasticity...
  2. doi request reprint Changes in rat hippocampal CA1 synapses following imipramine treatment
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory and MIND Center, Aarhus University, DK 8000 Aarhus C, Denmark
    Hippocampus 18:631-9. 2008
    ..We speculate that the present findings may be explained by the establishment of new synaptic connections and by remodelling or transformation of existing synapses...
  3. doi request reprint Repeated electroconvulsive seizures increase the total number of synapses in adult male rat hippocampus
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory and MIND Center, Aarhus University, Aarhus C, Denmark
    Eur Neuropsychopharmacol 19:329-38. 2009
    ..Our results indicated that repeated ECS induces neurogenesis, synaptogenesis and remodelling of synapses in rat hippocampus. This could provide a potential mechanism to explain the therapeutic effect of ECS...
  4. doi request reprint Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression
    Fenghua Chen
    Stereology and Electron Microscopy Research Laboratory, Danish Neuroscience Centre, Aarhus Sygehus, Aarhus University Hospital, Noerrebrogade 44, DK 8000 Aarhus C, Denmark
    Hippocampus 20:1376-84. 2010
    ....
  5. pmc Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase
    Nicoletta Nava
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, Aarhus, Denmark Drs Nava, Chen, and Nyengaard Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Risskov, Denmark Drs Nava, Treccani, Liebenberg, Chen, and Wegener Pharmaceutical Research Center of Excellence, School of Pharmacy, North West University, Potchefstroom, South Africa Dr Wegener Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari and Center of Excellence on Neurodegenerative Diseases, Universita degli Studi di Milano, Milano, Italy Drs Treccani and Popoli
    Int J Neuropsychopharmacol 18:. 2014
    ....
  6. doi request reprint Quantitative hippocampal structural changes following electroconvulsive seizure treatment in a rat model of depression
    Susanne S Kaae
    Stereology and EM Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Synapse 66:667-76. 2012
    ..This study aims to investigate the effect of electroconvulsive seizures on behavior and hippocampal structure in a rat model of depression...
  7. doi request reprint Vortioxetine promotes early changes in dendritic morphology compared to fluoxetine in rat hippocampus
    Fenghua Chen
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, DK 8000 Aarhus C, Denmark Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, DK 8240 Risskov, Denmark Electronic address
    Eur Neuropsychopharmacol 26:234-45. 2016
    ..This implies that vortioxetine׳s effects on spine and dendritic morphology are mediated by mechanisms that go beyond serotonin reuptake inhibition. ..
  8. doi request reprint A new efficient method for synaptic vesicle quantification reveals differences between medial prefrontal cortex perforated and nonperforated synapses
    Nicoletta Nava
    Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced bioimaging, Aarhus University Hospital, 8000, Aarhus C, Denmark Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, 8240, Risskov, Denmark
    J Comp Neurol 522:284-97. 2014
    ..Moreover, a greater number of docked vesicles in PSs may promote a high synaptic strength of these synapses...
  9. doi request reprint Ultrastructure and mitochondrial numbers in pre- and postpubertal pig oocytes
    Hanne Skovsgaard Pedersen
    Department of Animal Science, Aarhus University, Blichers alle 20, DK 8830 Tjele, Denmark
    Reprod Fertil Dev 28:586-98. 2016
    ..The higher number of mitochondria in large pre- and postpubertal oocytes could have an influence on oocyte competence, by increasing the pool of mitochondria available for early embryonic development. ..