S M Daluge

Summary

Publications

  1. pmc 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity
    S M Daluge
    Glaxo Wellcome Inc, Research Triangle Park, North Carolina 27709, USA
    Antimicrob Agents Chemother 41:1082-93. 1997
  2. ncbi Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity
    W H Miller
    Division of Experimental Therapy, Wellcome Research Laboratories, Research Triangle Park, North Carolina 27709
    J Biol Chem 267:21220-4. 1992

Collaborators

  • E P Garvey
  • W H Miller
  • J E Reardon
  • R L Miller
  • S Hopkins
  • F L Boyd

Detail Information

Publications2

  1. pmc 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity
    S M Daluge
    Glaxo Wellcome Inc, Research Triangle Park, North Carolina 27709, USA
    Antimicrob Agents Chemother 41:1082-93. 1997
    ..Having demonstrated an excellent preclinical profile, 1592U89 has progressed to clinical evaluation in HIV-infected patients...
  2. ncbi Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity
    W H Miller
    Division of Experimental Therapy, Wellcome Research Laboratories, Research Triangle Park, North Carolina 27709
    J Biol Chem 267:21220-4. 1992
    ..Thus, the contrasting HIV-inhibitory activities of carbovir enantiomers were due to differential phosphorylation by cellular enzymes and not due to enantioselectivity of HIV reverse transcriptase...