J Macek

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint Rapid determination of pseudoephedrine in human plasma by high-performance liquid chromatography
    J Macek
    Pharmakl spol sro, Laboratory and Clinical Facility, Prague, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 766:289-94. 2002
  2. ncbi request reprint Determination of roxithromycin in human plasma by high-performance liquid chromatography with spectrophotometric detection
    J Macek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 723:233-8. 1999
  3. ncbi request reprint Rapid determination of tamsulosin in human plasma by high-performance liquid chromatography using extraction with butyl acetate
    J Macek
    Laboratory and Clinical Facility, Pharmakl s r o, Seydlerova 2451, CZ 15800 Prague 13, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 809:307-11. 2004
  4. ncbi request reprint Determination of mirtazapine in human plasma by liquid chromatography
    P Ptacek
    Pharmakl s r o, U Vojenske nemocnice 1200, CZ 16200 Prague 6, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 794:323-8. 2003
  5. ncbi request reprint Liquid chromatographic determination of carvedilol in human plasma
    P Ptacek
    Pharmakl s r o, U Vojenske nemocnice 1200, CZ 16200 Prague 6, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 789:405-10. 2003
  6. ncbi request reprint Determination of alendronate in human urine as 9-fluorenylmethyl derivative by high-performance liquid chromatography
    P Ptacek
    Pharmakl SRO, Prague, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 767:111-6. 2002
  7. ncbi request reprint Separation of finasteride and analogues
    J Macek
    Pharmakl spol sro, Laboratory and Clinical Facility, U vojenske nemocnice, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 764:207-15. 2001
  8. ncbi request reprint Rapid and simple high-performance liquid chromatographic determination of nimesulide in human plasma
    P Ptacek
    Pharmakl SRO, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 758:183-8. 2001
  9. ncbi request reprint Rapid determination of citalopram in human plasma by high-performance liquid chromatography
    J Macek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 755:279-85. 2001
  10. ncbi request reprint Determination of finasteride in human plasma by liquid-liquid extraction and high-performance liquid chromatography
    P Ptacek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 738:305-10. 2000

Collaborators

  • P Ptacek
  • J Klima

Detail Information

Publications14

  1. ncbi request reprint Rapid determination of pseudoephedrine in human plasma by high-performance liquid chromatography
    J Macek
    Pharmakl spol sro, Laboratory and Clinical Facility, Prague, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 766:289-94. 2002
    ..5 ml of plasma. Within-day and between-day precision expressed by relative standard deviation was less than 7% and inaccuracy did not exceed 8%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  2. ncbi request reprint Determination of roxithromycin in human plasma by high-performance liquid chromatography with spectrophotometric detection
    J Macek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 723:233-8. 1999
    ..Within-day and between-day precision expressed by relative standard deviation is less than 5% and inaccuracy does not exceed 9%. The assay was used for pharmacokinetic studies...
  3. ncbi request reprint Rapid determination of tamsulosin in human plasma by high-performance liquid chromatography using extraction with butyl acetate
    J Macek
    Laboratory and Clinical Facility, Pharmakl s r o, Seydlerova 2451, CZ 15800 Prague 13, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 809:307-11. 2004
    ..Within-day and between-day precision expressed by relative standard deviation was less than 10% and inaccuracy did not exceed 5%. The assay was applied to the analysis of samples from several pharmacokinetic studies...
  4. ncbi request reprint Determination of mirtazapine in human plasma by liquid chromatography
    P Ptacek
    Pharmakl s r o, U Vojenske nemocnice 1200, CZ 16200 Prague 6, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 794:323-8. 2003
    ..A low limit of quantitation (1.5 ng/ml) and a short time of analysis (4 min) makes this assay suitable for pharmacokinetic studies...
  5. ncbi request reprint Liquid chromatographic determination of carvedilol in human plasma
    P Ptacek
    Pharmakl s r o, U Vojenske nemocnice 1200, CZ 16200 Prague 6, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 789:405-10. 2003
    ..Dihydroergocristine mesylate was used as the internal standard. The between-day precision expressed by relative standard deviation was less than 6% and inaccuracy does not exceed 3%. The assay was used for pharmacokinetic studies...
  6. ncbi request reprint Determination of alendronate in human urine as 9-fluorenylmethyl derivative by high-performance liquid chromatography
    P Ptacek
    Pharmakl SRO, Prague, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 767:111-6. 2002
    ..5 ng/ml using 5 ml of urine. Within-day and between-day precision expressed by relative standard deviation was less than 8% and inaccuracy did not exceed 9%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  7. ncbi request reprint Separation of finasteride and analogues
    J Macek
    Pharmakl spol sro, Laboratory and Clinical Facility, U vojenske nemocnice, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 764:207-15. 2001
    ..Tandem mass spectrometry is recommended as the detection method for measuring concentrations <1 ng/ml, while cheaper spectrophotometric detection may be selected for determination of higher concentrations...
  8. ncbi request reprint Rapid and simple high-performance liquid chromatographic determination of nimesulide in human plasma
    P Ptacek
    Pharmakl SRO, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 758:183-8. 2001
    ..More than 20 samples can be analysed within 1 h. Within-day and between-day precision expressed by relative standard deviation is less than 5% and inaccuracy does not exceed 8%. The assay was used for pharmacokinetic studies...
  9. ncbi request reprint Rapid determination of citalopram in human plasma by high-performance liquid chromatography
    J Macek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 755:279-85. 2001
    ..96 ng/ml using 1 ml of plasma. Within- and between-day precision expressed by relative standard deviation was less than 7% and inaccuracy did not exceed 6%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  10. ncbi request reprint Determination of finasteride in human plasma by liquid-liquid extraction and high-performance liquid chromatography
    P Ptacek
    Pharmakl s r o, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 738:305-10. 2000
    ..Within-day and between-day precision expressed by relative standard deviation is less than 5% and inaccuracy does not exceed 8%. The assay was used for pharmacokinetic studies...
  11. ncbi request reprint Determination of cetirizine in human plasma by high-performance liquid chromatography
    J Macek
    Pharmakl s r o, U vojenske nemocnice, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 736:231-5. 1999
    ..5 ml of plasma. Within-day and between-day precision expressed by relative standard deviation was less than 10% and inaccuracy did not exceed 8%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  12. ncbi request reprint Rapid determination of omeprazole in human plasma by protein precipitation and liquid chromatography-tandem mass spectrometry
    J Macek
    Pharmakl s r o, Seydlerova 2451, CZ 15800 Prague 13, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 852:282-7. 2007
    ..2 to 1200 ng/ml. Within-day and between-day precision expressed by relative standard deviation was less than 5% and inaccuracy did not exceed 12%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  13. ncbi request reprint Rapid determination of valsartan in human plasma by protein precipitation and high-performance liquid chromatography
    J Macek
    Pharmakl s r o, Seydlerova 2451, CZ 15800 Prague 13, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 832:169-72. 2006
    ..2 ml of plasma. Within-day and between-day precision expressed by relative standard deviation was less than 5% and inaccuracy did not exceed 8%. The assay was applied to the analysis of samples from a pharmacokinetic study...
  14. ncbi request reprint Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of phenylephrine in human plasma and its application to a pharmacokinetic study
    P Ptacek
    Pharmakl s r o, Seydlerova 2451, CZ 15800 Prague 13, Czech Republic
    J Chromatogr B Analyt Technol Biomed Life Sci 858:263-8. 2007
    ..Within-day and between-day precision expressed by relative standard deviation was less than 12% and inaccuracy did not exceed 8% at all levels. The assay was applied to the analysis of samples from a pharmacokinetic study...