Colin Collins

Summary

Publications

  1. pmc ShatterProof: operational detection and quantification of chromothripsis
    Shaylan K Govind
    Ontario Institute for Cancer Research, M5G 0A3, Toronto, Canada
    BMC Bioinformatics 15:78. 2014
  2. pmc Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer
    Mark Jesus M Magbanua
    Department of Medicine, Division of Hematology Oncology, University of California San Francisco, USA
    BMC Cancer 12:78. 2012
  3. pmc Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target
    Colin C Collins
    Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia, Canada
    Mol Cancer Ther 11:775-83. 2012
  4. pmc ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
    Aurélie Thollet
    Universite de Lyon, Lyon, France
    Mol Cancer 9:291. 2010
  5. pmc Detection of recurrent rearrangement breakpoints from copy number data
    Anna Ritz
    Department of Computer Science, Brown University, Providence, RI, USA
    BMC Bioinformatics 12:114. 2011
  6. pmc Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies
    Wolfgang Jäger
    The Vancouver Prostate Centre and Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada
    Oncotarget 6:21522-32. 2015
  7. doi request reprint ORMAN: optimal resolution of ambiguous RNA-Seq multimappings in the presence of novel isoforms
    Phuong Dao
    School of Computing Science, Simon Fraser University, Burnaby, BC, Canada, Department of Genome Sciences, University of Washington, Seattle, WA, USA, Vancouver Prostate Centre and Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada and Division of Computer Science, School of Informatics and Computing, Indiana University, Bloomington, IN, USA
    Bioinformatics 30:644-51. 2014
  8. pmc The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo
    Abhijit Parolia
    Honours Biotechnology Program, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
    Mol Cancer 14:46. 2015
  9. pmc nFuse: discovery of complex genomic rearrangements in cancer using high-throughput sequencing
    Andrew McPherson
    School of Computing Science, Simon Fraser University, Vancouver, British Columbia V5A 1S6, Canada
    Genome Res 22:2250-61. 2012

Collaborators

  • Hui Xue
  • Alexander W Wyatt
  • S Cenk Sahinalp
  • Francesco Crea
  • Himisha Beltran
  • Mohammed Alshalalfa
  • Fan Mo
  • Martin Hirst
  • Evan E Eichler
  • Francesca Demichelis
  • Yuzhuo Wang
  • Mark A Rubin
  • Andrew McPherson
  • Martin Gleave
  • Wolfgang Jäger
  • Abhijit Parolia
  • Phuong Dao
  • Shaylan K Govind
  • Mark Jesus M Magbanua
  • Anna Ritz
  • Aurélie Thollet
  • Pier Luc Clermont
  • Shannon Awrey
  • Elai Davicioni
  • Hui Hsuan Liu
  • Anne Haegert
  • Nicholas Erho
  • Shawn Anderson
  • Dong Lin
  • Estelle Li
  • Hongwei Cheng
  • Tetsutaro Hayashi
  • Igor Moskalev
  • Cheryl D Helgason
  • Peter C Black
  • Varune Rohan Ramnarine
  • Claudia Janssen
  • Ladan Fazli
  • Nur Ridzwan Nur Saidy
  • John D Watson
  • Emre Karakoc
  • Nilgun Donmez
  • Theodorus van der Kwast
  • Ibrahim Numanagic
  • Paul C Boutros
  • Michael Fraser
  • Catalina Anghel
  • John D McPherson
  • Amin Zia
  • Faraz Hach
  • Robert G Bristow
  • Pablo H Hennings-Yeomans
  • Yen Yi Lin
  • Eduardo V Sosa
  • John W Park
  • Dan Pinkel
  • Jeff Simko
  • Charles J Ryan
  • Janet H Scott
  • Michael M Ittmann
  • Benjamin J Raphael
  • Pamela L Paris
  • Pascale A Cohen
  • Marie Villedieu
  • Lea Payen
  • Evelyne Grisard
  • Julie A Vendrell
  • Sandra E Ghayad
  • Sabrina Ben Larbi

Detail Information

Publications9

  1. pmc ShatterProof: operational detection and quantification of chromothripsis
    Shaylan K Govind
    Ontario Institute for Cancer Research, M5G 0A3, Toronto, Canada
    BMC Bioinformatics 15:78. 2014
    ..As such, findings of chromothripsis are difficult to compare and many cases likely escape detection altogether...
  2. pmc Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer
    Mark Jesus M Magbanua
    Department of Medicine, Division of Hematology Oncology, University of California San Francisco, USA
    BMC Cancer 12:78. 2012
    ..However, it is the molecular characterization of CTCs that offers insight into the biology of these tumor cells in the context of personalized treatment...
  3. pmc Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target
    Colin C Collins
    Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia, Canada
    Mol Cancer Ther 11:775-83. 2012
    ..The combination of genome sequencing and patient-derived xenografts can identify candidate therapeutic agents and evaluate them for personalized oncology...
  4. pmc ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
    Aurélie Thollet
    Universite de Lyon, Lyon, France
    Mol Cancer 9:291. 2010
    ..The precise mechanisms involved in ZNF217 pro-survival function are currently unknown, and utmost importance is given to deciphering the role of ZNF217 in cancer therapy response...
  5. pmc Detection of recurrent rearrangement breakpoints from copy number data
    Anna Ritz
    Department of Computer Science, Brown University, Providence, RI, USA
    BMC Bioinformatics 12:114. 2011
    ..Typically, the interior of a recurrent CNV is examined for genes or other loci associated with a phenotype. However, in some cases, such as gene truncations and fusion genes, the target of variant lies at the boundary of the variant...
  6. pmc Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies
    Wolfgang Jäger
    The Vancouver Prostate Centre and Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada
    Oncotarget 6:21522-32. 2015
    ..Investigations related to tumor biology and drug testing in these models are therefore more likely to be relevant to the disease state in patients. They represent a valuable tool for developing precision therapy in MIBC. ..
  7. doi request reprint ORMAN: optimal resolution of ambiguous RNA-Seq multimappings in the presence of novel isoforms
    Phuong Dao
    School of Computing Science, Simon Fraser University, Burnaby, BC, Canada, Department of Genome Sciences, University of Washington, Seattle, WA, USA, Vancouver Prostate Centre and Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada and Division of Computer Science, School of Informatics and Computing, Indiana University, Bloomington, IN, USA
    Bioinformatics 30:644-51. 2014
    ..ORMAN achieves this objective through a combinatorial optimization formulation, which is solved through well-known approximation algorithms, integer linear programs and heuristics...
  8. pmc The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo
    Abhijit Parolia
    Honours Biotechnology Program, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
    Mol Cancer 14:46. 2015
    ..Here, we further examine the relevance of PCGEM1 and PRNCR1 in PCa, and their relationship with AR signaling, using patient-derived xenograft models...
  9. pmc nFuse: discovery of complex genomic rearrangements in cancer using high-throughput sequencing
    Andrew McPherson
    School of Computing Science, Simon Fraser University, Vancouver, British Columbia V5A 1S6, Canada
    Genome Res 22:2250-61. 2012
    ..Finally, we illustrate how CGRs may be used to infer the gene expression history of a tumor...