Charles S Cleeland

Summary

Publications

  1. doi request reprint Assessing the Symptoms of Cancer Using Patient-Reported Outcomes (ASCPRO): searching for standards
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:1077-85. 2010
  2. pmc Serum sTNF-R1, IL-6, and the development of fatigue in patients with gastrointestinal cancer undergoing chemoradiation therapy
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Brain Behav Immun 26:699-705. 2012
  3. pmc Levels of symptom burden during chemotherapy for advanced lung cancer: differences between public hospitals and a tertiary cancer center
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 29:2859-65. 2011
  4. pmc Inflammatory cytokines are associated with the development of symptom burden in patients with NSCLC undergoing concurrent chemoradiation therapy
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Brain Behav Immun 24:968-74. 2010
  5. ncbi request reprint Health care providers' assessments of the quality of advanced-cancer care in Latin American medical institutions: a comparison of predictors in five countries: Argentina, Brazil, Cuba, Mexico, and Peru
    Isabel Torres-Vigil
    Department of Health Disparities Research, Center for Research on Minority Health at The University of Texas M D Anderson Cancer Center, Houston, TX 77021, USA
    J Pain Palliat Care Pharmacother 22:7-20. 2008
  6. pmc Patterns of symptom burden during radiotherapy or concurrent chemoradiotherapy for head and neck cancer: a prospective analysis using the University of Texas MD Anderson Cancer Center Symptom Inventory-Head and Neck Module
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 120:1975-84. 2014
  7. pmc High symptom burden prior to radiation therapy for head and neck cancer: a patient-reported outcomes study
    G Brandon Gunn
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Head Neck 35:1490-8. 2013
  8. pmc Impact of cultural and linguistic factors on symptom reporting by patients with cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1450, Houston, TX 77030, USA
    J Natl Cancer Inst 102:732-8. 2010
  9. ncbi request reprint Pain education for underserved minority cancer patients: a randomized controlled trial
    Karen O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Blvd, Box 221, Houston, TX 77030, USA
    J Clin Oncol 22:4918-25. 2004
  10. doi request reprint Assessment of fatigue in cancer patients and community dwellers: validation study of the Filipino version of the brief fatigue inventory
    Tito R Mendoza
    Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex 77030, USA
    Oncology 79:112-7. 2010

Detail Information

Publications88

  1. doi request reprint Assessing the Symptoms of Cancer Using Patient-Reported Outcomes (ASCPRO): searching for standards
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:1077-85. 2010
    ....
  2. pmc Serum sTNF-R1, IL-6, and the development of fatigue in patients with gastrointestinal cancer undergoing chemoradiation therapy
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Brain Behav Immun 26:699-705. 2012
    ..0001). This longitudinal study suggests a role for over-expressed sTNF-R1 and IL-6 in the development of fatigue and other severe sickness symptoms during CXRT in patients with colorectal or esophageal cancer...
  3. pmc Levels of symptom burden during chemotherapy for advanced lung cancer: differences between public hospitals and a tertiary cancer center
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 29:2859-65. 2011
    ..We compared risk factors for high disease- and treatment-related symptom burden over 15 weeks of therapy in medically underserved patients with advanced non-small-cell lung cancer and in patients treated at a tertiary cancer center...
  4. pmc Inflammatory cytokines are associated with the development of symptom burden in patients with NSCLC undergoing concurrent chemoradiation therapy
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Brain Behav Immun 24:968-74. 2010
    ....
  5. ncbi request reprint Health care providers' assessments of the quality of advanced-cancer care in Latin American medical institutions: a comparison of predictors in five countries: Argentina, Brazil, Cuba, Mexico, and Peru
    Isabel Torres-Vigil
    Department of Health Disparities Research, Center for Research on Minority Health at The University of Texas M D Anderson Cancer Center, Houston, TX 77021, USA
    J Pain Palliat Care Pharmacother 22:7-20. 2008
    ....
  6. pmc Patterns of symptom burden during radiotherapy or concurrent chemoradiotherapy for head and neck cancer: a prospective analysis using the University of Texas MD Anderson Cancer Center Symptom Inventory-Head and Neck Module
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 120:1975-84. 2014
    ..The goals were to understand the onset and trajectory of specific symptoms and their severity, identify clusters, and facilitate symptom interventions and clinical trial design...
  7. pmc High symptom burden prior to radiation therapy for head and neck cancer: a patient-reported outcomes study
    G Brandon Gunn
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Head Neck 35:1490-8. 2013
    ..As a first step toward developing effective strategies to control symptoms associated with head and neck cancer (HNC) and its treatment, we sought to describe the pattern of symptoms experienced before radiation therapy...
  8. pmc Impact of cultural and linguistic factors on symptom reporting by patients with cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1450, Houston, TX 77030, USA
    J Natl Cancer Inst 102:732-8. 2010
    ..In multinational clinical trials, cultural and linguistic variations in patient-reported outcomes instruments could confound the interpretation of study results...
  9. ncbi request reprint Pain education for underserved minority cancer patients: a randomized controlled trial
    Karen O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Blvd, Box 221, Houston, TX 77030, USA
    J Clin Oncol 22:4918-25. 2004
    ..Previous studies found that African American and Hispanic cancer patients are at risk for undertreatment of pain. We evaluated the efficacy of a pain education intervention for underserved minority patients...
  10. doi request reprint Assessment of fatigue in cancer patients and community dwellers: validation study of the Filipino version of the brief fatigue inventory
    Tito R Mendoza
    Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Tex 77030, USA
    Oncology 79:112-7. 2010
    ..We developed and validated a Filipino language version of the Brief Fatigue Inventory (BFI-F) for describing the prevalence and severity of fatigue among Filipino patients with cancer...
  11. pmc Measuring the symptom burden of lung cancer: the validity and utility of the lung cancer module of the M. D. Anderson Symptom Inventory
    Tito R Mendoza
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, Texas 77030, USA
    Oncologist 16:217-27. 2011
    ....
  12. doi request reprint The M. D. Anderson symptom inventory-head and neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositis
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 72:1355-61. 2008
    ....
  13. pmc Using group-based trajectory modeling to examine heterogeneity of symptom burden in patients with head and neck cancer undergoing aggressive non-surgical therapy
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX, 77030, USA
    Qual Life Res 22:2331-9. 2013
    ..We applied group-based trajectory modeling (GBTM) to describe the heterogeneity of symptom burden among patients with head and neck cancer and to identify subgroups with distinct symptom-development trajectories...
  14. pmc Caregiver symptom burden: the risk of caring for an underserved patient with advanced cancer
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:1070-9. 2011
    ..In this longitudinal study, the authors assessed changes in symptom severity in caregivers and underserved minority patients diagnosed with advanced solid tumors who were being treated at public hospitals...
  15. ncbi request reprint The utility and validity of the modified brief pain inventory in a multiple-dose postoperative analgesic trial
    Tito R Mendoza
    Pain Research Group, Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Clin J Pain 20:357-62. 2004
    ..Our objective was to validate use of the modified Brief Pain Inventory through reanalysis of pain data from a multiple-dose, placebo-controlled, randomized trial of analgesia after coronary artery bypass graft surgery...
  16. ncbi request reprint Adequacy of cancer pain management in a Japanese Cancer Hospital
    Toru Okuyama
    Department of Symptom Research, Division of Anesthesiology and Critical Care, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Jpn J Clin Oncol 34:37-42. 2004
    ..Pain is one of the most frequent and deleterious symptoms in cancer patients. This study was carried out to investigate the adequacy of pain management at the National Cancer Center Hospital East, Japan...
  17. pmc The symptom burden of cancer: Evidence for a core set of cancer-related and treatment-related symptoms from the Eastern Cooperative Oncology Group Symptom Outcomes and Practice Patterns study
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 119:4333-40. 2013
    ..Using data from a large, multicenter, prospective study, the authors assessed the effects of disease site and stage on the percentages of patients rating these proposed symptoms as moderate to severe...
  18. pmc Subclinical pretreatment sensory deficits appear to predict the development of pain and numbness in patients with multiple myeloma undergoing chemotherapy
    Elisabeth G Vichaya
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Cancer Chemother Pharmacol 71:1531-40. 2013
    ..g., pain and numbness) in patients with MM undergoing treatment with chemotherapy...
  19. ncbi request reprint Chinese version of the M. D. Anderson Symptom Inventory: validation and application of symptom measurement in cancer patients
    Xin Shelley Wang
    Division of Internal Medicine, Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:1890-901. 2004
    ..Because disease-related and treatment-related symptoms most often occur in clusters, there is a global need for a standardized multiple-symptom assessment tool...
  20. pmc Pain, depression, and fatigue in community-dwelling adults with and without a history of cancer
    Cielito C Reyes-Gibby
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    J Pain Symptom Manage 32:118-28. 2006
    ..21; 95%CI = 1.06,1.37), and pain (OR = 1.15; 95%CI = 1.03,1.28). Symptom clusters were also more prevalent among those with a history of cancer (P < 0.001), with the pain-depression-fatigue cluster as most prevalent...
  21. pmc Prognostic value of symptom burden for overall survival in patients receiving chemotherapy for advanced nonsmall cell lung cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 116:137-45. 2010
    ..However, translating patient-reported outcomes into useful prognostic information for individual patients has been problematic...
  22. pmc Capturing the patient's experience: using qualitative methods to develop a measure of patient-reported symptom burden: an example from ovarian cancer
    Loretta A Williams
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA Electronic address
    J Pain Symptom Manage 46:837-45. 2013
    ..Although best methods for acquiring this input are not yet identified, patient input early in instrument development ensures that instrument content captures information most important and relevant to patients in understandable terms...
  23. ncbi request reprint A cytokine-based neuroimmunologic mechanism of cancer-related symptoms
    Bang Ning Lee
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Neuroimmunomodulation 11:279-92. 2004
    ..These concepts open exciting new avenues for translational research in the pathophysiology and treatment of cancer-related symptoms...
  24. pmc Acute cognitive impairment in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant
    Desiree Jones
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 119:4188-95. 2013
    ....
  25. pmc Automated symptom alerts reduce postoperative symptom severity after cancer surgery: a randomized controlled clinical trial
    Charles S Cleeland
    The University of Texas MD Anderson Cancer Center, Department of Symptom Research, 1515 Holcombe Blvd, Box 1450, Houston, TX 77030, USA
    J Clin Oncol 29:994-1000. 2011
    ..This study examined whether at-home symptom monitoring plus feedback to clinicians about severe symptoms contributes to more effective postoperative symptom control...
  26. ncbi request reprint An urban community's preferences for hypothetical outcomes of analgesic pain treatment
    Guadalupe R Palos
    Department of Symptom Research, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Pain Symptom Manage 32:470-7. 2006
    ..Knowledge of public preferences can help clinicians better understand factors that influence treatment choices and may help them motivate their patients to adhere to analgesic regimens...
  27. ncbi request reprint Japanese version of the MD Anderson Symptom Inventory: a validation study
    Toru Okuyama
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    J Pain Symptom Manage 26:1093-104. 2003
    ..Both factor analysis and cluster analysis showed the consistency of the statistical structure of the English and Japanese versions, indicating the cross-cultural validity of the scale...
  28. ncbi request reprint The association between symptom burdens and utility in Chinese cancer patients
    Ya Chen Tina Shih
    Section of Health Services Research, Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Qual Life Res 15:1427-38. 2006
    ..This study explored the relationship between the M. D. Anderson Symptom Inventory (MDASI), an instrument measuring the severity of symptoms common to patients with cancer, and utility derived from the SF-36...
  29. pmc Measuring Therapy-Induced Peripheral Neuropathy: Preliminary Development and Validation of the Treatment-Induced Neuropathy Assessment Scale
    Tito R Mendoza
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas Electronic address
    J Pain 16:1032-43. 2015
    ..The nonpainful component of neuropathy may be more disabling than the pain component...
  30. pmc Longitudinal analysis of patient-reported symptoms post-autologous stem cell transplant and their relationship to inflammation in patients with multiple myeloma
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Leuk Lymphoma 56:1335-41. 2015
    ..014). Maintenance therapy and tumor response were not related to high symptom burden. Associations between inflammation and symptom burden in this exploratory study warrant further confirmatory study. ..
  31. pmc Predictors of significant worsening of patient-reported fatigue over a 1-month timeframe in ambulatory patients with common solid tumors
    Michael J Fisch
    Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 120:442-50. 2014
    ..Understanding the determinants of fatigue worsening may help distinguish between different fatigue phenotypes and inform clinical trial designs...
  32. pmc Validation of the M. D. Anderson Symptom Inventory multiple myeloma module
    Desiree Jones
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, 77030, Houston, TX 77030, USA
    J Hematol Oncol 6:13. 2013
    ..We sought to validate a module of the M. D. Anderson Symptom Inventory (MDASI) developed specifically for patients with MM (MDASI-MM)...
  33. doi request reprint Congruence of primary brain tumor patient and caregiver symptom report
    Terri S Armstrong
    Department of Family Health, University of Texas Health Science Center School of Nursing, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 118:5026-37. 2012
    ..This study was conducted to evaluate the congruence of symptom reporting in patient and caregiver dyads, examining potential impact of NC impairment and Karnofsky performance status (KPS)...
  34. pmc Does recall period have an effect on cancer patients' ratings of the severity of multiple symptoms?
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 40:191-9. 2010
    ..Choosing an appropriate recall period for symptom assessment in a clinical trial is dependent on the design and purpose of the trial...
  35. pmc Assessing persistent cancer pain: a comparison of current pain ratings and pain recalled from the past week
    Qiuling Shi
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 37:168-74. 2009
    ..Our results provide information that might guide the choice of recall period for cancer clinical trials with pain as a self-reported outcome...
  36. pmc Pain in aging community-dwelling adults in the United States: non-Hispanic whites, non-Hispanic blacks, and Hispanics
    Cielito C Reyes-Gibby
    Department of Epidemiology, UT MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Pain 8:75-84. 2007
    ..54-2.43), being a Medicaid recipient (OR, 1.63; 99% CI, 1.17-2.25), and lower educational level (OR, 1.45; 99% CI, 1.14-1.85) were significant predictors for severe pain and helped to explain racial/ethnic differences in pain severity...
  37. ncbi request reprint End-of-life care in urban areas of China: a survey of 60 oncology clinicians
    Xin Shelley Wang
    Department of Symptom Research, World Health Organization s Collaborating Center on Supportive Cancer Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 27:125-32. 2004
    ..Results of the survey suggest specific training and research in symptom management that might improve end-of-life care for Chinese cancer patients...
  38. pmc Racial/ethnic disparities in inflammatory gene single-nucleotide polymorphisms as predictors of a high risk for symptom burden in patients with multiple myeloma 1 year after diagnosis
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 121:1138-46. 2015
    ..This study was conducted to determine whether any regulatory single-nucleotide polymorphism (SNP) in an inflammatory gene was associated with a high symptom burden in patients 1 year after the diagnosis of multiple myeloma (MM)...
  39. pmc Automated pain intervention for underserved minority women with breast cancer
    Karen O Anderson
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 121:1882-90. 2015
    ..The authors evaluated the feasibility and efficacy of an automated pain intervention for improving pain and symptom management of underserved African American and Latina women with breast cancer...
  40. pmc The validity and utility of the M. D. Anderson Symptom Inventory in patients with breast cancer: evidence from the symptom outcomes and practice patterns data from the eastern cooperative oncology group
    Tito R Mendoza
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX Electronic address
    Clin Breast Cancer 13:325-34. 2013
    ..Although the original MDASI validation study encompassed various cancer types, the instrument's psychometric properties have not been examined in a homogenous sample of patients with breast cancer in a national multicenter study...
  41. doi request reprint Recommendations for including multiple symptoms as endpoints in cancer clinical trials: a report from the ASCPRO (Assessing the Symptoms of Cancer Using Patient-Reported Outcomes) Multisymptom Task Force
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 119:411-20. 2013
    ..A representation of changes in multiple symptoms would clarify the impact of treatment and enhance the interpretation of cancer clinical trials for clinicians, patients, and those who make health care policy...
  42. ncbi request reprint Validation study of the Chinese version of the Brief Fatigue Inventory (BFI-C)
    Xin Shelley Wang
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 27:322-32. 2004
    ..The BFI-C is a valid, reliable instrument to measure the severity and impact of cancer-related fatigue among Chinese patients...
  43. pmc Serum interleukin-6 predicts the development of multiple symptoms at nadir of allogeneic hematopoietic stem cell transplantation
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:2102-9. 2008
    ..However, the mechanism underlying the development of multiple symptoms has not been established...
  44. ncbi request reprint Pain and fatigue in community-dwelling adults
    Cielito C Reyes-Gibby
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Pain Med 4:231-7. 2003
    ..We also assessed the prevalence of mild, moderate, and severe fatigue for this sample...
  45. ncbi request reprint Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults
    Karen O Anderson
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Boulevard, Box 221, Houston, TX 77030, USA
    J Pain Symptom Manage 25:307-18. 2003
    ..Although the majority of the psychiatric patients reported sleep disturbance, their sleep disturbance scores were not significantly associated with fatigue severity...
  46. pmc Favorable patient reported outcomes following IMRT for early carcinomas of the tonsillar fossa: Results from a symptom assessment study
    G Brandon Gunn
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA Electronic address
    Radiother Oncol 117:132-8. 2015
    ..A questionnaire-based study was conducted to assess long-term patient reported outcomes (PROs) following definitive IMRT-based treatment for early stage carcinomas of the tonsillar fossa...
  47. pmc Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Tex, USA
    Oncology 90:127-35. 2016
    ..Predicting which patients will likely develop CIPN is an ongoing clinical challenge...
  48. pmc Nomogram for predicting symptom severity during radiation therapy for head and neck cancer
    Tommy Sheu
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Baylor College of Medicine, Houston, Texas, USA
    Otolaryngol Head Neck Surg 151:619-26. 2014
    ..We created and evaluated 2 multivariate models and generated a nomogram to predict symptom severity during RT based on a patient-reported outcome (PRO) instrument, the MD Anderson Symptom Inventory-Head and Neck Module (MDASI-HN)...
  49. pmc Measuring the symptom burden associated with the treatment of chronic myeloid leukemia
    Loretta A Williams
    Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Blood 122:641-7. 2013
    ..The MDASI-CML is a valid and reliable symptom assessment instrument that can be used in clinical studies of symptom status in patients with CML...
  50. pmc The validity and utility of the MD Anderson Symptom Inventory in patients with prostate cancer: evidence from the Symptom Outcomes and Practice Patterns (SOAPP) data from the Eastern Cooperative Oncology Group
    Desiree Jones
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX Electronic address
    Clin Genitourin Cancer 12:41-9. 2014
    ..Although the original MDASI validation study encompassed various cancer types, the instrument's psychometric properties have not been examined in a large homogeneous sample of patients with prostate cancer...
  51. doi request reprint Reducing the toxicity of cancer therapy: recognizing needs, taking action
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX 77030, USA
    Nat Rev Clin Oncol 9:471-8. 2012
    ..With an emphasis on coordinating multidisciplinary efforts, this panel has presented a strategy to increase funding for the field and develop a coherent research agenda...
  52. ncbi request reprint Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy
    Lajos Pusztai
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cytokine 25:94-102. 2004
    ..The objective of this study was to assess changes in plasma levels of interleukin (IL)-1beta, IL-6, IL-8, IL-10, IL-12, and TNF-alpha during chemotherapy and to correlate these changes with musculoskeletal symptoms...
  53. ncbi request reprint Brief cognitive-behavioral audiotape interventions for cancer-related pain: Immediate but not long-term effectiveness
    Karen O Anderson
    Department of Symptom Research, Division of Internal Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:207-14. 2006
    ..A randomized clinical trial was performed evaluating the efficacy of 3 brief cognitive-behavioral techniques: relaxation, distraction, and positive mood interventions...
  54. pmc Symptom burden in cancer survivors 1 year after diagnosis: a report from the American Cancer Society's Studies of Cancer Survivors
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 117:2779-90. 2011
    ....
  55. doi request reprint Psychometric testing of the MDASI-HF: a symptom assessment instrument for patients with cancer and concurrent heart failure
    Anecita Fadol
    Department of Cardiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Card Fail 14:497-507. 2008
    ..This study evaluated the psychometric properties of the MD Anderson Symptom Inventory--Heart Failure (MDASI-HF), a 27-item self-report assessment instrument for patients with cancer and concurrent HF...
  56. ncbi request reprint Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson symptom inventory, head and neck module
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 29:923-31. 2007
    ....
  57. pmc Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer
    Hee Chul Park
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 75:775-81. 2009
    ..To investigate whether symptom burden before and during preoperative chemoradiation therapy (CRT) for rectal cancer predicts for pathologic tumor response...
  58. ncbi request reprint Asking the community about cutpoints used to describe mild, moderate, and severe pain
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Pain 7:49-56. 2006
    ..Our findings also support encouraging the general public to use a 0 to 10 scale to rate their pain intensity...
  59. doi request reprint Validation and application of a module of the M. D. Anderson Symptom Inventory for measuring multiple symptoms in patients with gastrointestinal cancer (the MDASI-GI)
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:2053-63. 2010
    ..The authors report the development of an MDASI module for use in patients with gastrointestinal (GI) cancer (the MDASI-GI)...
  60. pmc Inflammatory markers and development of symptom burden in patients with multiple myeloma during autologous stem cell transplantation
    Xin Shelley Wang
    Authors Affiliations Departments of Symptom Research, Stem Cell Transplantation, Hematopathology, Lymphoma Myeloma, and Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Clin Cancer Res 20:1366-74. 2014
    ..In this longitudinal study, we examined inflammatory factors related to the development of high symptom burden during autologous hematopoietic stem cell transplant (AuSCT) for multiple myeloma...
  61. pmc Validating the M. D. Anderson Symptom Inventory (MDASI) for use in patients with ovarian cancer
    Mary H Sailors
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX 77030, USA
    Gynecol Oncol 130:323-8. 2013
    ..We describe the validity and sensitivity of a module of the MDASI to be used with patients having ovarian cancer (MDASI-OC)...
  62. pmc Anastrozole-associated joint pain and other symptoms in patients with breast cancer
    Qiuling Shi
    Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain 14:290-6. 2013
    ..Having AI-associated joint pain correlated with increase in or persistence of other symptoms likely related to AI therapy. Further research is needed to validate predictors of AI-associated symptoms...
  63. pmc Translational approaches to treatment-induced symptoms in cancer patients
    Robert Dantzer
    Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Nat Rev Clin Oncol 9:414-26. 2012
    ..Ultimately, this knowledge will allow derivation of mechanism-based interventions to prevent or alleviate cancer-related symptoms...
  64. pmc Prospective, observational study of pain and analgesic prescribing in medical oncology outpatients with breast, colorectal, lung, or prostate cancer
    Michael J Fisch
    The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 30:1980-8. 2012
    ..Pain is prevalent among patients with cancer, yet pain management patterns in outpatient oncology are poorly understood...
  65. ncbi request reprint Filipino version of the M. D. Anderson Symptom Inventory: validation and multisymptom measurement in cancer patients
    Xin Shelley Wang
    Department of Symptom Research X S W, H G, T R M, C S C, Division of Internal Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 31:542-52. 2006
    ..Cancer patients reported significantly greater symptom severity on multiple items than did the community sample. The MDASI-F is reliable and valid for evaluating cancer-related symptoms and their impact on Filipino cancer patients...
  66. doi request reprint Biological pathways and genetic variables involved in pain
    Qiuling Shi
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1450, Houston, TX 77030, USA
    Qual Life Res 19:1407-17. 2010
    ..This paper summarizes current knowledge of pain-related and analgesic-related pathways as well as genetic variations involved in pain perception and management...
  67. doi request reprint Development and initial validation of the thyroid cancer module of the M. D. Anderson Symptom Inventory
    Ibrahima Gning
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    Oncology 76:59-68. 2009
    ..The M. D. Anderson Symptom Inventory (MDASI) and its modules measure common symptoms related to cancer and its treatment. We report the development and initial validation of the MDASI-Thyroid Cancer module (MDASI-THY)...
  68. doi request reprint Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid
    Charles S Cleeland
    University of Texas, MD Anderson Cancer Center, Department of Symptom Research, Houston, Texas 77030, USA
    Cancer 119:832-8. 2013
    ..In this study, the authors evaluated the effect of denosumab versus zoledronic acid (ZA) on pain in patients with advanced breast cancer and bone metastases...
  69. doi request reprint Integrating pain metrics into oncology clinical trials
    Charles S Cleeland
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:6646-50. 2011
    ..A number of methodologic and logistical challenges that hinder the ability to assess pain response in clinical trials are discussed in this article. Possible ways to address these challenges are also discussed...
  70. ncbi request reprint Longitudinal study of the relationship between chemoradiation therapy for non-small-cell lung cancer and patient symptoms
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:4485-91. 2006
    ....
  71. doi request reprint Clinical utility of the MDASI-BT in patients with brain metastases
    Terri S Armstrong
    Department of Integrative Nursing Care, The University of Texas Health Science Center School of Nursing, Houston, Texas 77030, USA
    J Pain Symptom Manage 37:331-40. 2009
    ..The MDASI-BT demonstrated validity and reliability in brain metastases patients and can be used to identify and monitor symptom occurrence in relation to treatment course and survival...
  72. ncbi request reprint Pediatric cancer pain management practices and attitudes in China
    Xin Shelley Wang
    Department of Symptom Research, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 26:748-59. 2003
    ..10, CI=1.31-3.37), and belief that children are less sensitive to pain (OR=1.96, CI=1.02-3.76). The top barriers to optimal pediatric pain management were identified as fear of opioid addiction and inadequate knowledge of pain management...
  73. ncbi request reprint Lessons learned from a multiple-dose post-operative analgesic trial
    Tito R Mendoza
    Pain Research Group, Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 221, Houston, TX 77030, USA
    Pain 109:103-9. 2004
    ....
  74. pmc Changes in pain and other symptoms in patients with painful multiple myeloma-related vertebral fracture treated with kyphoplasty or vertebroplasty
    Tito R Mendoza
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Pain 13:564-70. 2012
    ....
  75. pmc Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1-2 trial
    Xin Shelley Wang
    Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Lancet Oncol 13:395-402. 2012
    ..We investigated the clinical benefit of SBRT for managing spinal metastases and reducing cancer-related symptoms...
  76. ncbi request reprint The measurement of pain from metastatic bone disease: capturing the patient's experience
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 12:6236s-6242s. 2006
    ..These and other considerations in the design of clinical trials are discussed...
  77. ncbi request reprint Perceptions of analgesic use and side effects: what the public values in pain management
    Guadalupe R Palos
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    J Pain Symptom Manage 28:460-73. 2004
    ..To achieve better pain outcomes, clinicians and patients must identify factors that contribute to conservative decision-making about analgesic use and side effect management...
  78. ncbi request reprint What predicts the quality of advanced cancer care in Latin America? A look at five countries: Argentina, Brazil, Cuba, Mexico, and Peru
    Isabel Torres Vigil
    Center for Research on Minority Health, Department of Health Disparities Research, University of Texas M D Anderson Cancer Center, Houston, Texas 77021, USA
    J Pain Symptom Manage 34:315-27. 2007
    ....
  79. doi request reprint Symptom burden in cancer survivorship
    V Shannon Burkett
    The Department of Symptom Research, The University of Texas M D Anderson Cancer Center, 1100 Holcombe Blvd, Unit 221, Houston, TX 77030, USA
    J Cancer Surviv 1:167-75. 2007
    ..This paper contrasts symptom burden with general HRQOL and addresses the importance of including symptom burden as research tool throughout the trajectory of cancer survivorship...
  80. ncbi request reprint Validation study of the Japanese version of the brief fatigue inventory
    Toru Okuyama
    Pain Research Group, Division of Anesthesiology and Critical Care, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Pain Symptom Manage 25:106-17. 2003
    ..Additionally, fatigue severity classification was explored using the BFI-J. The results indicated that the BFI-J is a brief, valid, and feasible measure of fatigue for use with Japanese cancer patients...
  81. ncbi request reprint When is it justified to treat symptoms? Measuring symptom burden
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Oncology (Williston Park) 16:64-70. 2002
    ..Finally, we discuss potential research challenges and offer recommendations on future research directions...
  82. ncbi request reprint People in pain: how do they seek relief?
    Qiuling Shi
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Pain 8:624-36. 2007
    ..Difficulty communicating with health professionals and lack of health insurance contributed to inadequate pain relief. Almost all people with pain used multiple methods to control their pain...
  83. ncbi request reprint Variations in patients' self-report of pain by treatment setting
    Cielito C Reyes-Gibby
    Pain Research Group, Department of Symptom Research, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Pain Symptom Manage 25:444-8. 2003
    ....
  84. ncbi request reprint Rapid improvement in pain management: the Veterans Health Administration and the institute for healthcare improvement collaborative
    Charles S Cleeland
    Pain Research Group, Department of Symptom Research, U T M D Anderson Cancer Center, Houston, Texas, USA
    Clin J Pain 19:298-305. 2003
    ..With the goal of rapid improvement in pain management, a joint Collaborative (Veterans Health Administration and Institute for Healthcare Improvement) was conducted from May 2000 to January 2001...
  85. doi request reprint Assessment of cancer-related neuropathy and neuropathic pain
    Charles S Cleeland
    University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 15:13-8. 2010
    ....
  86. ncbi request reprint Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms
    Charles S Cleeland
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 97:2919-25. 2003
    ..These symptoms include pain, wasting, fatigue, cognitive impairment, anxiety, and depression, many of which co-occur. There is growing recognition that at least some of these symptoms may share common biologic mechanisms...
  87. ncbi request reprint Cancer pain management among underserved minority outpatients: perceived needs and barriers to optimal control
    Karen O Anderson
    Department of Symptom Research, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 94:2295-304. 2002
    ..Structured interviews allowed the authors to probe for previously unidentified barriers to pain management in these populations...
  88. ncbi request reprint The role of statins in cancer therapy
    Katja Hindler
    Division of Cardiovascular Anesthesiology, the Texas Heart Institute at St Luke s Episcopal Hospital, 6720 Bertner Avenue, Houston, Texas 77030, USA
    Oncologist 11:306-15. 2006
    ..The feasibility and efficacy of statins for the prevention and treatment of cancer is reviewed...