Yi Hua Zhou

Summary

Country: China

Publications

  1. ncbi request reprint Immunobiology and Host Response to HEV
    Yihua Zhou
    Departments of Experimental Medicine and Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhong Shan Road, Nanjing, 210008, China
    Adv Exp Med Biol 948:113-141. 2016
  2. pmc Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women
    Matthew S Payne
    School of Women s and Infants Health, The University of Western Australia, King Edward Memorial Hospital, 374 Bagot Road, Subiaco 6008, Western Australia, Australia
    BMC Pregnancy Childbirth 14:340. 2014
  3. doi request reprint Triptolide promotes generation of FoxP3+ T regulatory cells in rats
    Gutian Zhang
    Department of Urology, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhong Shan Road, Nanjing 210008, China
    J Ethnopharmacol 125:41-6. 2009
  4. doi request reprint Association of polymorphisms of cytokine and TLR-2 genes with long-term immunity to hepatitis B in children vaccinated early in life
    Yangyang Wang
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    Vaccine 30:5708-13. 2012
  5. pmc Detection of hepatitis B virus DNA among accepted blood donors in Nanjing, China
    Yong Liu
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    Virol J 7:193. 2010
  6. doi request reprint Incidence and seroprevalence of hepatitis E virus infection in pregnant women infected with hepatitis B virus and antibody placental transfer in infants
    Hongyu Huang
    Department of Experimental Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing 210008, China Electronic address
    J Clin Virol 82:84-8. 2016
  7. pmc Gaps in the prevention of perinatal transmission of hepatitis B virus between recommendations and routine practices in a highly endemic region: a provincial population-based study in China
    Yali Hu
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    BMC Infect Dis 12:221. 2012
  8. pmc Transplacentally acquired maternal antibody against hepatitis B surface antigen in infants and its influence on the response to hepatitis B vaccine
    Zhiqun Wang
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    PLoS ONE 6:e25130. 2011
  9. pmc Kinetics of IgG antibody to cytomegalovirus (CMV) after birth and seroprevalence of anti-CMV IgG in Chinese children
    Jie Chen
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
    Virol J 9:304. 2012
  10. pmc Kinetic Changes of Viremia and Viral Antigens of Hepatitis B Virus During and After Pregnancy
    Jingli Liu
    From the Department of Experimental Medicine JL, YB, MP, Y HZ, Jiangsu Key Laboratory for Molecular Medicine JL, MP, yh, Y HZ Department of Obstetrics and Gynecology JC, YH Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China Y HZ Zhenjiang Fourth People s Hospital CX, TC and Department of Obstetrics and Gynecology, Taixing People s Hospital, Jiangsu, China LL, Bx
    Medicine (Baltimore) 94:e2001. 2015

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Immunobiology and Host Response to HEV
    Yihua Zhou
    Departments of Experimental Medicine and Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhong Shan Road, Nanjing, 210008, China
    Adv Exp Med Biol 948:113-141. 2016
    ....
  2. pmc Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women
    Matthew S Payne
    School of Women s and Infants Health, The University of Western Australia, King Edward Memorial Hospital, 374 Bagot Road, Subiaco 6008, Western Australia, Australia
    BMC Pregnancy Childbirth 14:340. 2014
    ..This study tested if second trimester amniotic fluid cytokine levels, Ureaplasma sp. colonisation and sexual activity predict preterm birth and explain the differential preterm birth rates in Chinese compared to Australian women...
  3. doi request reprint Triptolide promotes generation of FoxP3+ T regulatory cells in rats
    Gutian Zhang
    Department of Urology, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhong Shan Road, Nanjing 210008, China
    J Ethnopharmacol 125:41-6. 2009
    ..Triptolide (TPT), a component of the Chinese herb Triptergium wilfordii, has potent immunosuppressive and anti-inflammatory activity and is used clinically in recipients of kidney transplantation...
  4. doi request reprint Association of polymorphisms of cytokine and TLR-2 genes with long-term immunity to hepatitis B in children vaccinated early in life
    Yangyang Wang
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    Vaccine 30:5708-13. 2012
    ..037). Our findings demonstrate that IL-4 gene polymorphisms may affect the long-term immune response to hepatitis B vaccine...
  5. pmc Detection of hepatitis B virus DNA among accepted blood donors in Nanjing, China
    Yong Liu
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    Virol J 7:193. 2010
    ..This study aimed to investigate the occult HBV infection in accepted blood donors in Nanjing, China...
  6. doi request reprint Incidence and seroprevalence of hepatitis E virus infection in pregnant women infected with hepatitis B virus and antibody placental transfer in infants
    Hongyu Huang
    Department of Experimental Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing 210008, China Electronic address
    J Clin Virol 82:84-8. 2016
    ..Hepatitis E has poor outcomes in pregnant women. Superinfection of hepatitis E virus (HEV) in patients infected with hepatitis B virus (HBV) may worsen liver disease...
  7. pmc Gaps in the prevention of perinatal transmission of hepatitis B virus between recommendations and routine practices in a highly endemic region: a provincial population-based study in China
    Yali Hu
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    BMC Infect Dis 12:221. 2012
    ..In the present investigation, we aimed to identify gaps in immunoprophylaxis of perinatal transmission of HBV between recommendations and routine practices in Jiangsu Province, China...
  8. pmc Transplacentally acquired maternal antibody against hepatitis B surface antigen in infants and its influence on the response to hepatitis B vaccine
    Zhiqun Wang
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    PLoS ONE 6:e25130. 2011
    ..Whether maternal antibody against hepatitis B surface antigen (anti-HBs) in infants may influence the long-term immunogenicity of hepatitis B vaccine remains unknown...
  9. pmc Kinetics of IgG antibody to cytomegalovirus (CMV) after birth and seroprevalence of anti-CMV IgG in Chinese children
    Jie Chen
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
    Virol J 9:304. 2012
    ..Prevalence of cytomegalovirus (CMV) infection is 90-100% in developing countries; however, the kinetics of anti-CMV IgG in infants remains elusive...
  10. pmc Kinetic Changes of Viremia and Viral Antigens of Hepatitis B Virus During and After Pregnancy
    Jingli Liu
    From the Department of Experimental Medicine JL, YB, MP, Y HZ, Jiangsu Key Laboratory for Molecular Medicine JL, MP, yh, Y HZ Department of Obstetrics and Gynecology JC, YH Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China Y HZ Zhenjiang Fourth People s Hospital CX, TC and Department of Obstetrics and Gynecology, Taixing People s Hospital, Jiangsu, China LL, Bx
    Medicine (Baltimore) 94:e2001. 2015
    ..This demonstrates that pregnancy has little influence on the HBV replication and antigen expression...
  11. pmc Cytomegalovirus seroprevalence in pregnant women and association with adverse pregnancy/neonatal outcomes in Jiangsu Province, China
    Shu Zhang
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    PLoS ONE 9:e107645. 2014
    ..In this study, we aimed to determine the provincial population-based seroprevalence in pregnant women and to further explore the association of maternal CMV infection status and adverse pregnancy/neonatal/growth outcomes in Jiangsu, China...
  12. pmc Rare detection of occult hepatitis B virus infection in children of mothers with positive hepatitis B surface antigen
    Yong Liu
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, China
    PLoS ONE 9:e112803. 2014
    ..We recommend that homology comparison of sequences recovered from the child and mother be used to define the occult HBV infection in children born to HBV infected mothers. ..
  13. pmc Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H7N9
    Rui Huang
    Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
    PLoS ONE 9:e101788. 2014
    ..The novel finding of simultaneous development of IgG, IgM, and IgA responses in acute H7N9 infection points to the potential for live influenza viruses to elicit fast and potent protective antibodies to limit the infection. ..
  14. pmc Breastfeeding is not a risk factor for mother-to-child transmission of hepatitis B virus
    Xiangru Chen
    Faculty of Nursing, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
    PLoS ONE 8:e55303. 2013
    ..The aim of this study was to determine whether breastfeeding may add risk for perinatal HBV transmission...
  15. doi request reprint Seroprevalence of hepatitis B surface antigen among pregnant women in Jiangsu, China, 17 years after introduction of hepatitis B vaccine
    Shu Zhang
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, China
    Int J Gynaecol Obstet 109:194-7. 2010
    ..To estimate the prevalence of hepatitis B surface antigen (HBsAg) among pregnant women in Jiangsu Province, eastern China, 17years after vaccination against hepatitis B virus (HBV) was introduced...
  16. pmc Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy
    Chao Wu
    Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu, PR China
    Virol J 7:370. 2010
    ..We aimed to clarify whether soluble CD40 ligand (sCD40L) activated B cells may be loaded with HBcAg18-27 peptide and served as antigen-producing cells (APCs) to induce HBV-specific cytolytic T lymphocytes (CTLs)...
  17. doi request reprint Virological Determinants of Spontaneous Postpartum e Antigen Seroconversion and Surface Antigen Seroclearance in Pregnant Women Infected with Hepatitis B Virus
    Yali Hu
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University, Medical School, Nanjing, China Jiangsu Key Laboratory for Molecular Medicine, Nanjing Drum Tower Hospital, Nanjing University, Medical School, Nanjing, China
    Arch Med Res 47:207-13. 2016
    ..We investigated the virological factors predicting spontaneous postpartum hepatitis B e antigen (HBeAg) seroconversion and hepatitis B surface antigen (HBsAg) seroclearance in pregnant women infected with hepatitis B virus (HBV)...
  18. pmc Clinical and Virological Characteristics of Chronic Hepatitis B Patients with Coexistence of HBsAg and Anti-HBs
    Yong Liu
    Department of Experimental Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210008, China
    PLoS ONE 11:e0146980. 2016
    ..3% (2/14) patients. In conclusion, coexistence of HBsAg and anti-HBs may be associated with higher frequency of mutations in the a determinant of HBV genotype C. ..
  19. doi request reprint Minimal adverse influence of maternal hepatitis B carrier status on perinatal outcomes and child's growth
    Jie Chen
    a Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, China
    J Matern Fetal Neonatal Med 28:2192-6. 2015
    ..To clarify whether maternal HBsAg positivity may add risk for adverse neonatal outcomes and even affect child's growth...
  20. pmc High hepatitis B virus load is associated with hepatocellular carcinomas development in Chinese chronic hepatitis B patients: a case control study
    Jin Yong Zhou
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    Virol J 9:16. 2012
    ..This study aimed to clarify whether the high HBV DNA level is associated with HCC development by comparing HBV DNA levels between HBV infected patients with and without HCC...
  21. doi request reprint A novel hepatitis B virus mutant coexisting with wild type virus in a carrier with negative HBsAg yet positive HBeAg and anti-HBs
    Yi Hua Zhou
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    J Clin Virol 46:363-6. 2009
    ..Occult infection of hepatitis B virus (HBV) has important impacts on both public health and clinical medicine...
  22. pmc Low titers of measles antibody in mothers whose infants suffered from measles before eligible age for measles vaccination
    Hong Zhao
    Department of Infectious Diseases, Nanjing Second Hospital, Nanjing, China
    Virol J 7:87. 2010
    ..The mean measles neutralizing titer in the vaccinated mothers and in 13 age-match women with the histories of clinical measles were compared...
  23. pmc Hepatitis E virus seroprevalence in pregnant women in Jiangsu, China, and postpartum evolution during six years
    Guangyu Gu
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210008, China
    BMC Infect Dis 15:560. 2015
    ..The previous surveys of anti-HEV seroprevalence are cross-sectional. This study aimed to investigate the prevalence of infection among pregnant women and their children in Jiangsu, China, and to observe postpartum anti-HEV evolution...
  24. doi request reprint Occult hepatitis B virus infection with positive hepatitis B e antigen
    Zhenge Han
    Department of Laboratory Medicine, East China Sanatorium, Wuxi 214065, Jiangsu Province, China Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
    Clin Chim Acta 438:266-8. 2015
    ..Occult HBV infection (OBI), referred to persistence of HBV DNA in serum and/or liver without detectable serum hepatitis B surface (HBsAg), usually has low HBV DNA levels. The presence of HBeAg in OBI is unusual...
  25. pmc Monitoring human cytomegalovirus infection with nested PCR: comparison of positive rates in plasma and leukocytes and with quantitative PCR
    Shu Zhang
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
    Virol J 7:73. 2010
    ..Total DNA was extracted separately from plasma and peripheral blood leukocytes (PBL) of each sample. HCMV DNA was detected in parallel by nested PCR and quantitative real-time PCR (qRT-PCR), and the results were compared...
  26. doi request reprint Minimization of hepatitis B infection among children in Jiangsu, China, 12years after integration of hepatitis B vaccine into the expanded program on immunization
    Xiaoqian Lin
    Department of Obstetrics and Gynecology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
    Vaccine 34:6458-6463. 2016
    ..China has integrated hepatitis B vaccine into the Expanded Program on Immunization since 2002. We aimed to survey the seroprevalence of and immunity to hepatitis B virus (HBV) in children born from 2002 to 2014 in Jiangsu, China...
  27. pmc Avian influenza A(H7N9) virus screening in patients with fever and flu-like symptoms in a tertiary hospital in an area with confirmed cases
    Chao Wu
    Department of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China
    PLoS ONE 8:e82613. 2013
    ....
  28. doi request reprint A knowledge survey of obstetrics and gynecology staff on the prevention of mother-to-child transmission of hepatitis B virus
    Yali Hu
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing Medical University, Jiangsu, China
    J Infect Dev Ctries 7:391-7. 2013
    ..This survey was designed to investigate the knowledge awareness of obstetrics and gynaecology staff (Obs/Gyn staff) on the prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV)...
  29. pmc Application of truncated immunodominant polypeptide from hepatitis E virus (HEV) ORF2 in an assay to exclude nonspecific binding in detecting anti-HEV immunoglobulin M
    Jin shun Pan
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
    J Clin Microbiol 48:779-84. 2010
    ..Together, the data indicate that the poor reactivity of a truncated ORF2 polypeptide can be used to exclude nonspecific binding in the detection of anti-HEV IgM...
  30. ncbi request reprint [Establishment of long-term culture system for human B cells derived from peripheral blood mononuclear cells activated via soluble CD40 ligand]
    Chao Wu
    Department of Infectious Diseases, Drum Tower Clinical College of Nanjing Medical University, Nanjing 210008, China
    Zhonghua Yi Xue Za Zhi 89:124-7. 2009
    ....
  31. ncbi request reprint Vaccination against hepatitis B: the Chinese experience
    Yi Hua Zhou
    Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, China
    Chin Med J (Engl) 122:98-102. 2009
    ..To review the implementation of mass vaccination of hepatitis B vaccine and its critical role in prevention of hepatitis B virus infection in China...
  32. doi request reprint Influence of maternal antibody against hepatitis B surface antigen on active immune response to hepatitis B vaccine in infants
    Yali Hu
    Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhong Shan Road, Nanjing, China
    Vaccine 26:6064-7. 2008
    ..The long-term efficacy of hepatitis B vaccine in infants with high titers of maternal anti-HBs remains to be further evaluated...