Jian Ji

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. ncbi A novel urethane containing copolymer as a surface modification additive for blood contact materials
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou, 310027, China
    J Mater Sci Mater Med 13:677-84. 2002
  2. ncbi A novel crosslinkable polymer as drug-loaded coating for biomedical device
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Mater Sci Mater Med 15:137-43. 2004
  3. ncbi Fabrication of alternating polycation and albumin multilayer coating onto stainless steel by electrostatic layer-by-layer adsorption
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    Colloids Surf B Biointerfaces 34:185-90. 2004
  4. ncbi [Studies on crosslinkable coatings for biomedical application]
    Jian Ji
    Department of Polymer Science and Composite Materials, Zhejiang University, Hangzhou 310027, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21:122-5. 2004
  5. ncbi Surface tailoring of poly(DL-lactic acid) by ligand-tethered amphiphilic polymer for promoting chondrocyte attachment and growth
    Jian Ji
    Department of Polymer Science and Engineering, Zhejiang University, 310027, Hangzhou, China
    Biomaterials 25:1859-67. 2004
  6. ncbi Preparation of albumin preferential surfaces on poly(vinyl chloride) membranes via surface self-segregation
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou, 310027, China
    J Biomed Mater Res 61:252-9. 2002
  7. ncbi Surface engineering of poly(D,L-lactic acid) by entrapment of chitosan-based derivatives for the promotion of chondrogenesis
    Huiguang Zhu
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res 62:532-9. 2002
  8. ncbi Selective binding of albumin on stearyl poly(ethylene oxide) coupling polymer-modified poly(ether urethane) surfaces
    D A Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, PR China
    J Biomater Sci Polym Ed 12:1123-46. 2001
  9. ncbi Surface engineering of poly(DL-lactic acid) by entrapment of alginate-amino acid derivatives for promotion of chondrogenesis
    Huiguang Zhu
    Department of Polymer Science, Zhejiang University, Hangzhou, China
    Biomaterials 23:3141-8. 2002
  10. ncbi Novel biomimetic polymersomes as polymer therapeutics for drug delivery
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P R China
    J Control Release 107:502-12. 2005

Collaborators

Detail Information

Publications88

  1. ncbi A novel urethane containing copolymer as a surface modification additive for blood contact materials
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou, 310027, China
    J Mater Sci Mater Med 13:677-84. 2002
    ..The surface for attracting and reversibly binding albumin, which was proved to suppress the platelet adhesion and prolong the clotting time, has been developed by the simple coating of the novel SMA in SPU...
  2. ncbi A novel crosslinkable polymer as drug-loaded coating for biomedical device
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Mater Sci Mater Med 15:137-43. 2004
    ..Rhodamine S and Cibacron Blue were used as model drugs to prepare drug-containing coating at the same conditions. Drug-releasing curves indicated that the mechanism of the release is approximately Fickian release...
  3. ncbi Fabrication of alternating polycation and albumin multilayer coating onto stainless steel by electrostatic layer-by-layer adsorption
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    Colloids Surf B Biointerfaces 34:185-90. 2004
    ..Such an easy processing and shape-independent method may have good potential for surface modification of cardiovascular devices...
  4. ncbi [Studies on crosslinkable coatings for biomedical application]
    Jian Ji
    Department of Polymer Science and Composite Materials, Zhejiang University, Hangzhou 310027, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21:122-5. 2004
    ..The in-vitro platelet-adhesion test and the plasma recalcification time(PRT) determination showed that the coated surface could resist the blood coagulation effectively...
  5. ncbi Surface tailoring of poly(DL-lactic acid) by ligand-tethered amphiphilic polymer for promoting chondrocyte attachment and growth
    Jian Ji
    Department of Polymer Science and Engineering, Zhejiang University, 310027, Hangzhou, China
    Biomaterials 25:1859-67. 2004
    ..This simple surface treatment method may have potentials for tissue engineering and other biomedical applications...
  6. ncbi Preparation of albumin preferential surfaces on poly(vinyl chloride) membranes via surface self-segregation
    Jian Ji
    Department of Polymer Science, Zhejiang University, Hangzhou, 310027, China
    J Biomed Mater Res 61:252-9. 2002
    ..Surfaces to attract and reversibly bind albumin, which might diminish the occurrence of thrombosis, inflammation, and infection, are developed by self-organizing blends of the amphiphilic comb polymer in poly(vinyl chlorides)...
  7. ncbi Surface engineering of poly(D,L-lactic acid) by entrapment of chitosan-based derivatives for the promotion of chondrogenesis
    Huiguang Zhu
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res 62:532-9. 2002
    ..The novel surface treatment method combines the good mechanical property of PDL-LA with the good cytocompatibility of chitosan derivatives, which may have potential for tissue engineering...
  8. ncbi Selective binding of albumin on stearyl poly(ethylene oxide) coupling polymer-modified poly(ether urethane) surfaces
    D A Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, PR China
    J Biomater Sci Polym Ed 12:1123-46. 2001
    ....
  9. ncbi Surface engineering of poly(DL-lactic acid) by entrapment of alginate-amino acid derivatives for promotion of chondrogenesis
    Huiguang Zhu
    Department of Polymer Science, Zhejiang University, Hangzhou, China
    Biomaterials 23:3141-8. 2002
    ..The novel surface treatment method may have potentials for tissue engineering and other biomedical applications...
  10. ncbi Novel biomimetic polymersomes as polymer therapeutics for drug delivery
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P R China
    J Control Release 107:502-12. 2005
    ..These experimental results suggested that the nanoparticles prepared from CMPC block copolymers could be a good candidate for injectable drug delivery carrier...
  11. ncbi In situ immobilization of proteins and RGD peptide on polyurethane surfaces via poly(ethylene oxide) coupling polymers for human endothelial cell growth
    Dong An Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P R China
    Biomacromolecules 3:1286-95. 2002
    ..The results also indicated that, for HUVEC in vitro cultivation, the cell adhesion stage was of particular importance and had a significant impact on the cell responses to the modified surfaces...
  12. ncbi Novel human endothelial cell-engineered polyurethane biomaterials for cardiovascular biomedical applications
    Dong An Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P R China
    J Biomed Mater Res A 65:498-510. 2003
    ..Therefore, these MPEO derivative-modified PEU materials are promising to serve as novel polymeric permanent implants or interventional devices for cardiovascular biomedical applications...
  13. ncbi [Blood compatibility of two novel polyurethane coating materials]
    Guanhua Yu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21:184-7. 2004
    ..The surface modified by Chi-MSPEO has longer PRT, whereas the surface modified by PEU-MSPEO has longer PT...
  14. doi Self-assembled chitosan/heparin multilayer film as a novel template for in situ synthesis of silver nanoparticles
    Weiyong Yuan
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, PR China
    Colloids Surf B Biointerfaces 76:549-55. 2010
    ..Our method of in situ synthesis of metal nanoparticles in biocompatible multilayer films might provide great potential to design biofunctional nanocomposite films...
  15. ncbi Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility
    Zuwei Ma
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res 63:838-47. 2002
    ..Moreover, the chondrocytes were more spread out on the modified PLLA membranes than on the control PLLA membranes...
  16. ncbi Construction of anti-adhesive and antibacterial multilayer films via layer-by-layer assembly of heparin and chitosan
    Jinhong Fu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomaterials 26:6684-92. 2005
    ..9 and 6.0 decreased by 68%, 58% and 46%, respectively. Such an easy processing and shape-independent method to prepare an anti-adhesive and antibacterial surface may have good potential for surface modification of cardiovascular devices...
  17. doi Heparin/collagen multilayer as a thromboresistant and endothelial favorable coating for intravascular stent
    Quankui Lin
    MOE Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    J Biomed Mater Res A 96:132-41. 2011
    ..This surface coating may have great potential in facilitating in situ endothelialization of blood contacting materials...
  18. ncbi Osteoblast growth promotion by protein electrostatic self-assembly on biodegradable poly(lactide)
    Huiguang Zhu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Biomater Sci Polym Ed 16:761-74. 2005
    ..It may be a good choice for the surface modification of complex biomedical devices. These very flexible systems allow broad medical applications for drug delivery and tissue engineering...
  19. doi In situ endothelialization of intravascular stents coated with an anti-CD34 antibody functionalized heparin-collagen multilayer
    Quankui Lin
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization of the Ministry of Education, Zhejiang University, Hangzhou, China
    Biomaterials 31:4017-25. 2010
    ....
  20. doi The effect of a cholesterol liquid crystalline structure on osteoblast cell behavior
    Jian ping Xu
    Department of Polymer Science, Key Laboratory of Macromolecule Synthesis and Functionalization of Minster of Education, Zhejiang University, Hangzhou, 310027, People s Republic of China
    Biomed Mater 4:025010. 2009
    ..In comparison to unannealed films, the annealed films with a cholesterol liquid crystalline structure could promote osteoblast cell attachment and growth significantly...
  21. ncbi Fabrication of thromboresistant multilayer thin film on plasma treated poly (vinyl chloride) surface
    Qinggang Tan
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, People s Republic of China
    J Mater Sci Mater Med 16:687-92. 2005
    ..Such an easy processing and shape-independent method may have good potential for surface modification of cardiovascular devices...
  22. ncbi Construction of multilayer coating onto poly-(DL-lactide) to promote cytocompatibility
    Huiguang Zhu
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    Biomaterials 25:109-17. 2004
    ..In comparison to conventional coating methods, polyelectrolyte multilayers are easy to prepare and the procedure is valid whatever the shape of the solid. It allows broad medical applications for drug delivery and tissue engineering...
  23. ncbi Surface engineering of poly(DL-lactide) via electrostatic self-assembly of extracellular matrix-like molecules
    Huiguang Zhu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomacromolecules 4:378-86. 2003
    ..It may be a good choice for the modification of 3-D scaffolds used in tissue engineering. These very flexible systems allow broad medical applications for drug delivery and tissue engineering...
  24. doi Cucurbit[8]uril supramolecular assembly for positively charged ultrathin films as nanocontainers
    Dan Dan Li
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    Langmuir 29:14101-7. 2013
    ..Finally, the films were successfully employed as nanocontainers for DNA loading and subsequent directing the transfection of the adhered cells. ..
  25. doi Multilayers based on cationic nanocomplexes for co-delivery of doxorubicin and DNA
    Jie Kan Sun
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    Colloids Surf B Biointerfaces 112:67-73. 2013
    ..Moreover, the multilayers have the ability to transfect cells through a substrate-mediated mode. The (PEI-Fc-DOX-DNA/DS) multilayers can be potentially applied to the biomedical devices for cancer treatment, regenerative medicine, etc. ..
  26. doi Self-assembly of near-monodisperse redox-sensitive micelles from cholesterol-conjugated biomimetic copolymers
    Yin Wang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Macromol Biosci 13:1084-91. 2013
    ..MTT study shows that the as-prepared micelles has good biocompatibility to both normal and cancer cells. These properties indicate that these micelles may be used as promising drug delivery vehicles...
  27. doi Multidentate zwitterionic chitosan oligosaccharide modified gold nanoparticles: stability, biocompatibility and cell interactions
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Nanoscale 5:3982-91. 2013
    ..This kind of multidentate zwitterionic chitosan derivative could be widely used for stabilizing other inorganic nanoparticles, which will greatly improve their performance in a variety of bio-related applications...
  28. doi Different complex surfaces of polyethyleneglycol (PEG) and REDV ligand to enhance the endothelial cells selectivity over smooth muscle cells
    Yu Wei
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, PR China
    Colloids Surf B Biointerfaces 84:369-78. 2011
    ..The combination of nonspecific resistance of short free PEG and the ECs selectivity of REDV peptide presents much better ability to enhance the competitive adhesion of HUVECs over HASMCs...
  29. ncbi Construction of antibacterial multilayer films containing nanosilver via layer-by-layer assembly of heparin and chitosan-silver ions complex
    Jinhong Fu
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization of Minster of Education, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res A 79:665-74. 2006
    ..The multilayer films containing nanosilver may have good potentials for surface modification of medical devices, especially for cardiovascular implants...
  30. doi Direct adhesion of endothelial cells to bioinspired poly(dopamine) coating through endogenous fibronectin and integrin α5 β1
    Jin lei Wang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Macromol Biosci 13:483-93. 2013
    ..These findings will lead to a better understanding of interactions between cells and PDA coating, paving the way for the further development of PDA...
  31. doi Surface engineering of cardiovascular stent with endothelial cell selectivity for in vivo re-endothelialisation
    Yu Wei
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomaterials 34:2588-99. 2013
    ..Consequently, the surface tailoring of a stent to obtain high endothelial cell selectivity is likely an effective design criterion for in situ endothelialisation and a possible future solution for the problem of in-stent restenosis...
  32. doi Zwitterionic polycarboxybetaine coating functionalized with REDV peptide to improve selectivity for endothelial cells
    Ying Ji
    Department of Polymer Science and Engineering, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Zhejiang University, Hangzhou 310027, People s Republic of China
    J Biomed Mater Res A 100:1387-97. 2012
    ..The existence of zwitterionic carboxybetaine helps to screen undesirable adsorption of platelets, and its nonspecific resistance to smooth muscle cells contributes to the realization of endothelial cell selectivity...
  33. ncbi Surface tailoring of poly(ethylene terephthalate) via ligand-tethered comb-like PEG to enhance endothelialization
    Xiaolin Li
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    J Mater Sci Mater Med 19:291-9. 2008
    ..Cell spread uniformly and covered completely on the PET-CPEG-lysine. The CPEG end tethered with L-lysine could regulate cell adhesion and growth and enhance surface endothelialization...
  34. doi BSA-tetraphenylethene derivative conjugates with aggregation-induced emission properties: fluorescent probes for label-free and homogeneous detection of protease and α1-antitrypsin
    Jian ping Xu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China
    Analyst 136:2315-21. 2011
    ....
  35. ncbi Selective adsorption of serum albumin on biomedical polyurethanes modified by a poly(ethylene oxide) coupling-polymer with cibacron blue (F3G-A) endgroups
    Dong An Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, PR China
    Bioconjug Chem 13:792-803. 2002
    ..Finally, the improvement of blood-compatibility on the modified surfaces was verified by the plasma recalcification time (PRT) test...
  36. ncbi A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating
    Weiyong Yuan
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, People s Republic of China
    J Biomed Mater Res B Appl Biomater 85:556-63. 2008
    ..The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light...
  37. ncbi Poly(D,L-lactic acid)-block-(ligand-tethered poly(ethylene glycol)) copolymers as surface additives for promoting chondrocyte attachment and growth
    Guanhua Yu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res B Appl Biomater 76:64-75. 2006
    ..The chondrocyte cytocompatibility test showed the modified PLA films could significantly improve chondrocyte attachment and proliferation...
  38. ncbi The effect of formation of the liquid crystalline phase on the blood compatibility of a cholesterol modified silicone
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, 310027, Hangzhou, People s Republic of China
    J Mater Sci Mater Med 16:277-82. 2005
    ..The positive results of liquid crystalline onto haemocompatibility allow broad potential in biomaterials...
  39. ncbi Constructing thromboresistant surface on biomedical stainless steel via layer-by-layer deposition anticoagulant
    Qinggang Tan
    Department of Polymer Science, Zhejiang University, Hangzhou 310027, China
    Biomaterials 24:4699-705. 2003
    ..Such an easy processing and shape-independent method may have good potential for surface modification of cardiovascular devices...
  40. doi Construction of redox-active multilayer film for electrochemically controlled release
    Yi Xin Sun
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, People s Repulblic of China
    Langmuir 29:11163-8. 2013
    ..The (PEI-Fc@drug/DNA) multilayer film may have potential applications in the field of biomedical and nanoscale devices. ..
  41. doi The effect of ligand composition on the in vivo fate of multidentate poly(ethylene glycol) modified gold nanoparticles
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomaterials 34:8370-81. 2013
    ..Together, the composition of multidentate ligands will not only affect the stability of NPs under extreme conditions but also result in quite different fate of NPs in vivo, which can be tailored case by case...
  42. doi Layer by layer self-assembly of poly[2-(methacryloyloxy) ethyl phosphorylcholine] multilayer via the ionic complexation with zirconium
    Shaopeng Pang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    Colloids Surf B Biointerfaces 94:22-6. 2012
    ..The adsorption of bovine serum albumin (BSA) and fetal bovine serum (FBS) on the PMPC surface was monitored by the QCM-D and spectroscopic ellipsometry, and the results showed the multilayer film have excellent protein resistance...
  43. doi Highly soluble PEGylated pyrene-gold nanoparticles dyads for sensitive turn-on fluorescent detection of biothiols
    Jian ping Xu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Analyst 135:2323-7. 2010
    ..Therefore an easily prepared, inexpensive, high solubility fluorescent probe has been realized and is also expected to detect other biological analytes of interest...
  44. doi Aggregation-induced emission of tetraphenylethene derivative as a fluorescence method for probing the assembling/disassembling of amphiphilic molecules
    Congshan Zhu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Analyst 136:3343-8. 2011
    ....
  45. doi Hyaluronic acid and chitosan-DNA complex multilayered thin film as surface-mediated nonviral gene delivery system
    Quan Kui Lin
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China
    Colloids Surf B Biointerfaces 74:298-303. 2009
    ..This kind of surface-mediated nonviral complex incorporated multilayer may have great potential in the localized and controlled delivery of DNA in biomedical implants and tissue engineering application...
  46. ncbi [Quantitative characterization of adsorbed bovine serum albumin on modified surfaces of poly(ether urethane) materials using ATR-FT-IR spectroscopy]
    Dongan Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 19:4-9. 2002
    ..The quantitative characterization was based on the optical principles of FT-IR, method of experiment and index of the apparatus, by which the enhancement of BSA adsorption on the SMA-modified surfaces was confirmed...
  47. ncbi pH controlled synthesis of high aspect-ratio gold nanorods
    Qingshan Wei
    College of Material Science and Chemical Engineering, Zhejiang University, Hangzhou, 310027, China
    J Nanosci Nanotechnol 8:5708-14. 2008
    ..This kind of high aspect-ratio gold nanorods could be excellent building blocks for optical or electrical nanodevices in future...
  48. ncbi Synthesis and characterization of cholesterol-poly(ethylene glycol)-poly(D,L-lactic acid) copolymers for promoting osteoblast attachment and proliferation
    Guanhua Yu
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Zhejiang University, Hangzhou 310027, PR China
    J Mater Sci Mater Med 17:899-909. 2006
    ..This simple surface treatment method may have potentials for tissue engineering and other biomedical applications...
  49. doi pH-amplified exponential growth multilayers: a facile method to develop hierarchical micro- and nanostructured surfaces
    Jinhong Fu
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization of Minster of Education, Zhejiang University, 310027 Hangzhou, China
    Langmuir 25:672-5. 2009
    ..The synergetic action of the pH-tunable charge density and diffusivity of the weak polyelectrolytes provides a new method for the enhanced growth of multilayers with hierarchal micro- and nanostructured surfaces...
  50. ncbi Protein electrostatic self-assembly on poly(DL-lactide) scaffold to promote osteoblast growth
    Huiguang Zhu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    J Biomed Mater Res B Appl Biomater 71:159-65. 2004
    ..These very flexible systems allow broad medical applications for drug delivery and tissue engineering...
  51. doi Improved Endothelial Function of Endothelial Cell Monolayer on the Soft Polyelectrolyte Multilayer Film with Matrix-Bound Vascular Endothelial Growth Factor
    Hao Chang
    MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    ACS Appl Mater Interfaces 8:14357-66. 2016
    ..g., glass, tissue culture polystyrene, and stainless steel). Our findings highlighted the influence of substrate stiffness on endothelial function of EC monolayer, giving a new strategy in the surface design of vascular implants. ..
  52. doi pH- and NIR Light-Responsive Polymeric Prodrug Micelles for Hyperthermia-Assisted Site-Specific Chemotherapy to Reverse Drug Resistance in Cancer Treatment
    Zuhong Li
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China
    Small 12:2731-40. 2016
    ..These results demonstrate that the well-designed IR-780 loaded polymeric prodrug micelles for hyperthermia-assisted site-specific chemotherapy present an effective approach to reverse drug resistance. ..
  53. doi Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 29:9138-48. 2013
    ..It demonstrates that cell interaction between nanoparticles and cells is not only affected by surface and size factors but also strongly depends on cell types...
  54. doi Enhanced retention and cellular uptake of nanoparticles in tumors by controlling their aggregation behavior
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    ACS Nano 7:6244-57. 2013
    ....
  55. doi Biocompatible micelles based on comb-like PEG derivates: formation, characterization, and photo-responsiveness
    Chao Jian Chen
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Macromol Rapid Commun 32:1077-81. 2011
    ..MTT assay revealed that the micelles are biocompatible. These photo-responsive micelles might have great potential for controlled release of hydrophobic drugs...
  56. doi A novel biomimetic polymer as amphiphilic surfactant for soluble and biocompatible carbon nanotubes (CNTs)
    Fang Ming Xu
    Department of Polymer Science, Key Laboratory of Macromolecule Synthesis and Functionalization of Minster of Education, Zhejiang University, Hangzhou 310027, PR China
    Colloids Surf B Biointerfaces 67:67-72. 2008
    ..The biocompatible CNTs represent an excellent nano-object for potential biomedical applications...
  57. doi Stiffness of polyelectrolyte multilayer film influences endothelial function of endothelial cell monolayer
    Hao Chang
    MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Colloids Surf B Biointerfaces 149:379-387. 2017
    ..Our study highlights the influence of substrate stiffness on endothelial function, which offers a new criterion for surface design of vascular implants...
  58. doi Biomimetic pseudopolyrotaxane prodrug micelles with high drug content for intracellular drug delivery
    Yin Wang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Chem Commun (Camb) 49:7123-5. 2013
    ..It is anticipated that this facile strategy may open a novel avenue for the development of multifunctional drug delivery systems. ..
  59. doi Electropolymerization of dopamine for surface modification of complex-shaped cardiovascular stents
    Jin lei Wang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomaterials 35:7679-89. 2014
    ..The proposed methodology may find applications in the area of metallic surface engineering, especially for the cardiovascular stents and potentially all biomedical devices with electroconductive surface as well. ..
  60. doi Mussel-inspired polydopamine: a biocompatible and ultrastable coating for nanoparticles in vivo
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China
    ACS Nano 7:9384-95. 2013
    ....
  61. doi Small and stable phosphorylcholine zwitterionic quantum dots for weak nonspecific phagocytosis and effective Tat peptide functionalization
    Xiangsheng Liu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    Adv Healthc Mater 2:352-60. 2013
    ..This research will provide insights into designing suitable ligands for surface modification of QDs and improving biofunctional QD performance in biological applications...
  62. ncbi Construction and deconstruction of PLL/DNA multilayered films for DNA delivery: effect of ionic strength
    Kefeng Ren
    Department of Polymer Science and Engineering, Zhejiang University, Zheda Road 38, Hangzhou, Zhejiang 310027, China
    Colloids Surf B Biointerfaces 46:63-9. 2005
    ..Taking the advantages of the LbL technique, the erasable PLL/DNA films could deposit onto a variety of surfaces, such as vascular stent, intervention catheter and tissue engineering scaffold, to serve as a novel DNA delivery system...
  63. ncbi Biomacromolecules electrostatic self-assembly on 3-dimensional tissue engineering scaffold
    Huiguang Zhu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027 China
    Biomacromolecules 5:1933-9. 2004
    ..It may be a promising choice for the surface modification of complex biomedical devices. These very flexible systems allow broad medical applications for drug delivery and tissue engineering...
  64. ncbi Tunable DNA release from cross-linked ultrathin DNA/PLL multilayered films
    Kefeng Ren
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Bioconjug Chem 17:77-83. 2006
    ....
  65. doi Polyamidoamine dendrimers surface-engineered with biomimetic phosphorylcholine as potential drug delivery carriers
    Lan Jia
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang Province, China
    Colloids Surf B Biointerfaces 84:49-54. 2011
    ..Biomimetic phosphorylcholine surface engineered PAMAM dendrimers with lowered cytotoxicity and high cellular penetrating ability showed great potential for the biomedical applications as nanocarrier system...
  66. doi Humidity responsive asymmetric free-standing multilayered film
    Liyan Shen
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 26:16634-7. 2010
    ..The bending/unbending movement of the free-standing film can be ascribed to the different responses of these two surfaces to humidity...
  67. doi Postdiffusion of oligo-peptide within exponential growth multilayer films for localized peptide delivery
    Xuefei Wang
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization, Ministry of Education, Zhejiang University, Hangzhou 310027, China
    Langmuir 25:11664-71. 2009
    ..The postdiffusion of oligo-peptide within an exponential growth multilayer can serve as an effective approach for localized and sustained peptide delivery...
  68. ncbi [A study on cytocompatibility of poly (lactic acid) membrane modified by polymer microspheres with different surface charges]
    Da Chen
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 22:966-70. 2005
    ..The positive charge on the surface of PLA membrane could improve the cell-compatibility of PLA well...
  69. doi Surface-mediated functional gene delivery: an effective strategy for enhancing competitiveness of endothelial cells over smooth muscle cells
    Hao Chang
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, PR China
    Biomaterials 34:3345-54. 2013
    ....
  70. pmc Asymmetric free-standing film with multifunctional anti-bacterial and self-cleaning properties
    Liyan Shen
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    ACS Appl Mater Interfaces 4:4476-83. 2012
    ..The broad-spectrum antimicrobial capability of silver ions released from the bottom surface coupled with superhydrophobic barrier protection of the upper surface may make the free-standing film a new therapy for open wound...
  71. doi Covalent layer-by-layer assembly of hyperbranched polyether and polyethyleneimine: multilayer films providing possibilities for surface functionalization and local drug delivery
    Xiaofen Hu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China
    Biomacromolecules 12:4264-71. 2011
    ..The studies on the drug loading and in vitro release behaviors of the multilayer films demonstrated their application potentials in local delivery of hydrophilic and hydrophobic therapeutic agents...
  72. ncbi Novel biomimetic surfactant: synthesis and micellar characteristics
    Jian ping Xu
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P R China
    Macromol Biosci 5:164-71. 2005
    ..The anti-cancer drug adriamycin (ADR) was chosen as a hydrophobic drug to be incorporated into the inner core of the micelles and the morphology of the drug-loaded micelles were observed by AFM...
  73. doi Netlike knitting of polyelectrolyte multilayers on honeycomb-patterned substrate
    Wei Sun
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 26:14236-40. 2010
    ..This research reported template-directed LBL patterning assembly for the first time. It provides a beneficial exploration for the surface patterning technique for the LBL assembly process...
  74. doi Construction of degradable multilayer films for enhanced antibacterial properties
    Bai Liang Wang
    MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    ACS Appl Mater Interfaces 5:4136-43. 2013
    ....
  75. doi Light-regulated host-guest interaction as a new strategy for intracellular PEG-detachable polyplexes to facilitate nuclear entry
    Wenyu Li
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, PR China
    Chem Commun (Camb) 48:10126-8. 2012
    ..The polyplexes had excellent colloidal stability and competition stability. Moreover, the intracellular light-regulated dePEGylation facilitated DNA release and nuclear entry, thus resulting in efficient transfection...
  76. doi Biomimetic polymersomes as carriers for hydrophilic quantum dots
    Gong Yan Liu
    MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 28:557-62. 2012
    ....
  77. doi Fluorescence detection of alkaline phosphatase activity with β-cyclodextrin-modified quantum dots
    Lan Jia
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Chem Commun (Camb) 46:7166-8. 2010
    ..An alkaline phosphatase activity detection system was constructed based on the different quenching effect of the enzyme substrate and product on the β-CD-functionalized CdTe QDs...
  78. ncbi Construction and enzymatic degradation of multilayered poly-l-lysine/DNA films
    Kefeng Ren
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomaterials 27:1152-9. 2006
    ..The well-structured, easy processed enzymatic biodegradable multilayered film may have great potential for gene applications in tissue engineering, medical implants, etc...
  79. doi Construction of multifunctional coatings via layer-by-layer assembly of sulfonated hyperbranched polyether and chitosan
    Xiaofen Hu
    Department of Polymer Science and Engineering, Key Laboratory of Macromolecule Synthesis and Functionalization of Minster of Education, Zhejiang University, 310027, Hangzhou, China
    Langmuir 26:2624-9. 2010
    ....
  80. ncbi Surface coating of stearyl poly(ethylene oxide) coupling-polymer on polyurethane guiding catheters with poly(ether urethane) film-building additive for biomedical applications
    D A Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China
    Biomaterials 22:1549-62. 2001
    ..The blood regular testing was carried out on the samples taken out at six different times (0, 5,10, 20, 30 and 60 min). The results were ideal. Finally, the SMA-MSPEO was proved to be non-acute-toxic by LD50 test...
  81. ncbi Stearyl poly(ethylene oxide) grafted surfaces for preferential adsorption of albumin
    J Ji
    Department of Polymer Science, Zhejiang University, Hangzhou, China
    Biomaterials 22:3015-23. 2001
    ..The surfaces prepared in this research attract and reversibly bind albumin due to the synergistic action of the PEO chains and the stearyl end groups...
  82. doi Gold-nanoparticle-stabilized pluronic micelles exhibiting glutathione triggered morphology evolution properties
    Jian ping Xu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 26:16841-7. 2010
    ..It is believed that the high stability and glutathione responsibility of the Au-NPs shell-cross-linked micelles allowed for high potential in drug delivery and biosensors...
  83. doi Mixed charged zwitterionic self-assembled monolayers as a facile way to stabilize large gold nanoparticles
    Xiangsheng Liu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Langmuir 27:5242-51. 2011
    ....
  84. doi pH-Amplified multilayer films based on hyaluronan: influence of HA molecular weight and concentration on film growth and stability
    Liyan Shen
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
    Biomacromolecules 12:1322-31. 2011
    ....
  85. doi Zwitterionic phosphorylcholine as a better ligand for gold nanorods cell uptake and selective photothermal ablation of cancer cells
    Wenbo Zhou
    Department of Polymer Science, Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Zhejiang University, Hangzhou, 310027, China
    Chem Commun (Camb) 46:1479-81. 2010
    ..The conjugation of zwitterionic phosphorylcholine onto gold nanorods leads to enhanced and selective uptake within cancer cells...
  86. ncbi Blends of stearyl poly(ethylene oxide) coupling-polymer in chitosan as coating materials for polyurethane intravascular catheters
    D A Wang
    Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, P. R. China
    J Biomed Mater Res 58:372-83. 2001
    ..Finally, the SMA-MSPEO was proved to be non-chronic-toxic by animal experiments with rats and suitable as a coating material for clinical use...
  87. doi Label-free fluorescence detection of mercury(II) and glutathione based on Hg2+-DNA complexes stimulating aggregation-induced emission of a tetraphenylethene derivative
    Jian ping Xu
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China
    Analyst 135:3002-7. 2010
    ..The target-aptamer complexes stimulating aggregation-induced emission therefore show great promise for environmental and biological process monitoring and disease diagnosis...
  88. ncbi Comparison of cell-suspension and explant culture of rabbit limbal epithelial cells
    Xiaomin Zhang
    Eye Centre of Tianjin Medical College, 64, Tongan road, Heping District, Tianjin 300070, People s Republic of China
    Exp Eye Res 80:227-33. 2005
    ....