Ai Min Bao

Summary

Affiliation: Zhejiang University
Country: China

Publications

  1. pmc Decreased plasma neuroactive amino acids and increased nitric oxide levels in melancholic major depressive disorder
    Yun Rong Lu
    Department of Neurobiology Key Laboratory of Medical Neurobiology of Ministry of Health of China Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, P, R, China
    BMC Psychiatry 14:123. 2014
  2. doi Sex differences in the brain, behavior, and neuropsychiatric disorders
    Ai Min Bao
    Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China
    Neuroscientist 16:550-65. 2010
  3. doi Sexual differentiation of the human brain: relation to gender identity, sexual orientation and neuropsychiatric disorders
    Ai Min Bao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Front Neuroendocrinol 32:214-26. 2011
  4. doi Alterations in the histaminergic system in Alzheimer's disease: a postmortem study
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Neurobiol Aging 33:2585-98. 2012
  5. doi Unaltered histaminergic system in depression: a postmortem study
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    J Affect Disord 146:220-3. 2013
  6. doi Nitric oxide synthase and nitric oxide alterations in chronically stressed rats: a model for nitric oxide in major depressive disorder
    Shang Feng Gao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang, PR China Lab of Neurosurgery, Institute of Nervous System Diseases, Xuzhou Medical College, Xuzhou 221004, Jiangsu, PR China
    Psychoneuroendocrinology 47:136-40. 2014
  7. doi Reduced GAD(65/67) immunoreactivity in the hypothalamic paraventricular nucleus in depression: a postmortem study
    Shang Feng Gao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China
    J Affect Disord 149:422-5. 2013
  8. doi MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer's disease
    Qiong Bin Zhu
    1 Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, P R China
    Brain 139:908-21. 2016
  9. doi Effect of pentobarbital and isoflurane on acute stress response in rat
    Xue yan Wu
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang Province Key Laboratory of Mental Disorder s Management, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Electronic address
    Physiol Behav 145:118-21. 2015
  10. doi Neuronal histaminergic system in aging and age-related neurodegenerative disorders
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Exp Gerontol 48:603-7. 2013

Collaborators

  • Dick F Swaab
  • Koen Bossers
  • Michel A Hofman
  • Sabina Luchetti
  • Hui Chun Li
  • Eus J W Van Someren
  • Ling Shan
  • Juan Li Wu
  • Shang Feng Gao
  • Xue yan Wu
  • Rawien Balesar
  • Li Gen Shi
  • Jing Lu
  • Qiong Bin Zhu
  • Yun Rong Lu
  • Xin Yan Fu
  • Jian Hong Luo
  • Bo Sun
  • Chun Qing Liu
  • Yu Ting Hu
  • Man li Huang
  • Juan Zhao
  • Unga Unmehopa
  • Zhao Pin Wang
  • Xin Rui Qi
  • Shi Hua Wu
  • Ronald Verwer
  • Si Yang Yu
  • Er Yu
  • Jia Li
  • Qi Jun Zhang
  • Lei Guo
  • Xiao Juan Weng
  • Yan Jiang
  • Wei bo Liu
  • Zheng Lin
  • Anne Klomp
  • F Swaab Dick
  • Daniel J van Wamelen
  • Ling Juan Ruan
  • Paul L Chazot
  • Natasha Lethbridge
  • Joop J van Heerikhuize

Detail Information

Publications23

  1. pmc Decreased plasma neuroactive amino acids and increased nitric oxide levels in melancholic major depressive disorder
    Yun Rong Lu
    Department of Neurobiology Key Laboratory of Medical Neurobiology of Ministry of Health of China Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, P, R, China
    BMC Psychiatry 14:123. 2014
    ..Here we want to establish whether changes in their plasma levels may serve as biomarker for the melancholic subtype of this disorder...
  2. doi Sex differences in the brain, behavior, and neuropsychiatric disorders
    Ai Min Bao
    Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China
    Neuroscientist 16:550-65. 2010
    ..Knowing that such a relationship exists may help bring about sex-specific therapeutic strategies...
  3. doi Sexual differentiation of the human brain: relation to gender identity, sexual orientation and neuropsychiatric disorders
    Ai Min Bao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Front Neuroendocrinol 32:214-26. 2011
    ....
  4. doi Alterations in the histaminergic system in Alzheimer's disease: a postmortem study
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Neurobiol Aging 33:2585-98. 2012
    ..011) and of the glia markers, glial fibrillary acidic protein-mRNA, vimentin-mRNA and proteolipid protein-mRNA. These findings indicate the presence of regional changes in the TMN that are at least partly gender-dependent...
  5. doi Unaltered histaminergic system in depression: a postmortem study
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    J Affect Disord 146:220-3. 2013
    ..Rodent experiments suggested that the neuronal histaminergic system may be involved in symptoms of depression...
  6. doi Nitric oxide synthase and nitric oxide alterations in chronically stressed rats: a model for nitric oxide in major depressive disorder
    Shang Feng Gao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang, PR China Lab of Neurosurgery, Institute of Nervous System Diseases, Xuzhou Medical College, Xuzhou 221004, Jiangsu, PR China
    Psychoneuroendocrinology 47:136-40. 2014
    ..In conclusion, the changes in plasma and hypothalamic NOS-NO of CUS rats and MDD were similar. The male CUS rat model may thus help us with our investigation of the mechanism underlying NOS-NO alterations in depression. ..
  7. doi Reduced GAD(65/67) immunoreactivity in the hypothalamic paraventricular nucleus in depression: a postmortem study
    Shang Feng Gao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China
    J Affect Disord 149:422-5. 2013
    ..The present study aimed at determining GABAergic input in the hypothalamic paraventricular nucleus (PVN) in depression and its correlation with the activity of corticotropin-releasing hormone (CRH) neurons...
  8. doi MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer's disease
    Qiong Bin Zhu
    1 Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, P R China
    Brain 139:908-21. 2016
    ....
  9. doi Effect of pentobarbital and isoflurane on acute stress response in rat
    Xue yan Wu
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang Province Key Laboratory of Mental Disorder s Management, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Electronic address
    Physiol Behav 145:118-21. 2015
    ..We aimed to reveal the interference of different anesthetics, i.e. intraperitoneal (i.p.) sodium-pentobarbital injection or isoflurane inhalation, with the acute stress responses in rats...
  10. doi Neuronal histaminergic system in aging and age-related neurodegenerative disorders
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Exp Gerontol 48:603-7. 2013
    ....
  11. doi Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Neurobiol Aging 33:1488.e1-13. 2012
    ..Our observations imply the presence of local changes in the histaminergic system that may contribute to PD pathology, and may thus provide a rationale for possible novel therapeutic strategies...
  12. pmc Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Sleep 35:713-5. 2012
    ....
  13. doi Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus
    Ling Shan
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang University School of Medicine, Hangzhou, China
    Neurobiol Aging 33:1343-4. 2012
    ..We conclude that neuronal histamine production remains largely unaltered in PD despite the abundant LB/LN accumulation in the TMN...
  14. doi Sex differences in the stress response in SD rats
    Jing Lu
    Department of Neurobiology Key Laboratory of Medical Neurobiology of Ministry of Health of China Zhejiang Province Key Laboratory of Mental Disorder s Management, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Behav Brain Res 284:231-7. 2015
    ..Stress affects the behavioral, endocrine and the molecular response of the stress systems in the hypothalamus of SD rats in a clear sexual dimorphic way, which has parallels in human data on stress and depression. ..
  15. ncbi [Alterations of plasma aspartic acid, glycine and asparagine levels in patients with major depressive disorder]
    Xin Yan Fu
    Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 41:132-8. 2012
    ..To evaluate the changes of plasma levels of the excitatory amino acid neurotransmitter aspartic acid (Asp), inhibitory neurotransmitter glycine (Gly) and asparagine (Asn) in patients with major depressive disorder (MDD)...
  16. ncbi [Progress in determination of histamine levels in biological samples]
    Juan Li Wu
    Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 41:681-8. 2012
    ..The aim of this review is to summarize the progress or effort made in this field, with focus on the high-performance liquid chromatography...
  17. ncbi [Research progress on role of ghrelin in brain]
    Jing Lu
    Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 41:689-95. 2012
    ..The aim of this review is to summarize the main findings in this field, with the purpose of promoting further studies on the role of ghrelin in the brain...
  18. doi Decreased NOS1 expression in the anterior cingulate cortex in depression
    Shang Feng Gao
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, PR China and
    Cereb Cortex 23:2956-64. 2013
    ..The diminished ACC-NOS1 expression and decreased CSF-NOx levels may be involved in the alterations of ACC activity in depression, possibly by affecting glutamatergic and GABAergic neurotransmission. ..
  19. doi The human histaminergic system in neuropsychiatric disorders
    Ling Shan
    Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China Netherlands Institute for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam 1105 BA, The Netherlands Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, Los Angeles, CA 90095, USA Neurobiology Research, Veterans Administration Greater Los Angeles Health Care System, 16111 Plummer Street, North Hills, CA 91343, USA
    Trends Neurosci 38:167-77. 2015
    ..Moreover, we discuss the potential for, and concerns over, the use of novel histamine 3 receptor (H3R) antagonists/inverse agonists as treatment for such disorders. ..
  20. ncbi [Maternal deprivation-induced stress responses in female rats]
    Bo Sun
    Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 41:125-31. 2012
    ..To investigate the effect of maternal deprivation on the activity of hypothalamo-pituitary-adrenal (HPA) axis, acute stress response and the sex hormone receptors expression in hypothalamic paraventricular nucleus (PVN) in female rats...
  21. doi A sensitive and practical RP-HPLC-FLD for determination of the low neuroactive amino acid levels in body fluids and its application in depression
    Juan Li Wu
    Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang Province Key Laboratory of Mental Disorder s Management, Zhejiang University School of Medicine, Hangzhou 310058, China
    Neurosci Lett 616:32-7. 2016
    ..The data indicate that this RP-HPLC-FLD protocol is applicable for detection of low levels of neuroactive AAs in body fluids, as well as for routine clinical applications. ..
  22. doi A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival post-mortem human brain tissue
    Chun Qing Liu
    Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China
    Methods 52:359-66. 2010
    ..In the present study, this is not only illustrated for HDC ISH, but also for corticotrophin-releasing hormone mRNA expression in the hypothalamic paraventricular nucleus...
  23. doi Corticotropin-releasing hormone and arginine vasopressin in depression focus on the human postmortem hypothalamus
    Ai Min Bao
    Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People s Republic of China
    Vitam Horm 82:339-65. 2010
    ..Both similarities and differences are found in the activity changes in the CRH and AVP systems in depressive disorders and depression in Alzheimer's disease...