Lei Zhang

Summary

Country: China

Publications

  1. doi request reprint Aberrant gene expression in deceased transgenic cloned calves
    L Zhang
    China Agricultural University, Haidian District, Beijing, PR China
    Anim Reprod Sci 112:182-9. 2009
  2. pmc Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle
    Bin Yang
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, People s Republic of China
    PLoS ONE 6:e17593. 2011
  3. pmc The identification of loci for immune traits in chickens using a genome-wide association study
    Lei Zhang
    Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, P R China Key Laboratory of Farm Animal Genetic Resources and Germplasm Innovation, Ministry of Agriculture, P R China, Beijing, P R China
    PLoS ONE 10:e0117269. 2015
  4. pmc Aberrant epigenetic changes and gene expression in cloned cattle dying around birth
    Li Lin
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Yuanmingyuan West Road 2, Beijing 100094, PR China
    BMC Dev Biol 8:14. 2008
  5. doi request reprint Identification and characterization of a cathepsin-L-like peptidase in Eimeria tenella
    Renqiang Liu
    National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, No 2 Yuan Ming Yuan West Road, Haidian District, Beijing, 100193, China
    Parasitol Res 113:4335-48. 2014
  6. ncbi request reprint Expression of insulin-like growth factors systems in cloned cattle dead within hours after birth
    Shijie Li
    The State Key Laboratory for Agrobiotechnology in Livestock and Poultry, China Agricultural University, Beijing, China
    Mol Reprod Dev 74:397-402. 2007
  7. doi request reprint Impacts of human lysozyme transgene on the microflora of pig feces and the surrounding soil
    Jie Zhao
    State Key Laboratory for Agrobiotechnology, College of Biological Science, China Agricultural University, Haidian District, Beijing 100193, People s Republic of China
    J Biotechnol 161:437-44. 2012
  8. ncbi request reprint Birth of calves expressing the enhanced green fluorescent protein after transfer of fresh or vitrified/thawed blastocysts produced by somatic cell nuclear transfer
    Guochun Gong
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
    Mol Reprod Dev 69:278-88. 2004
  9. doi request reprint Eimeria tenella: interleukin 17 contributes to host immunopathology in the gut during experimental infection
    Lei Zhang
    National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100193, China
    Exp Parasitol 133:121-30. 2013
  10. pmc The role of neoadjuvant chemotherapy for resectable colorectal liver metastases: a systematic review and meta-analysis
    Wei Liu
    Hepatopancreatobiliary Surgery Department I, Key laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, PR China
    Oncotarget 7:37277-37287. 2016

Collaborators

Detail Information

Publications15

  1. doi request reprint Aberrant gene expression in deceased transgenic cloned calves
    L Zhang
    China Agricultural University, Haidian District, Beijing, PR China
    Anim Reprod Sci 112:182-9. 2009
    ..To our knowledge, this is the first time that gene expression was examined in transgenic cloned cattle. These findings may have some implications in understanding the low efficiency of the transgenic cloning...
  2. pmc Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle
    Bin Yang
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, People s Republic of China
    PLoS ONE 6:e17593. 2011
    ..Lysozyme, a bactericidal protein that protects human infants from microbial infections, is highly expressed in human milk but is found in only trace amounts in cow milk...
  3. pmc The identification of loci for immune traits in chickens using a genome-wide association study
    Lei Zhang
    Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, P R China Key Laboratory of Farm Animal Genetic Resources and Germplasm Innovation, Ministry of Agriculture, P R China, Beijing, P R China
    PLoS ONE 10:e0117269. 2015
    ..Potentially useful candidate SNPs for marker-assisted selection for disease resistance are identified. It is highly likely that these candidate genes play roles in various aspects of the immune response in chickens. ..
  4. pmc Aberrant epigenetic changes and gene expression in cloned cattle dying around birth
    Li Lin
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Yuanmingyuan West Road 2, Beijing 100094, PR China
    BMC Dev Biol 8:14. 2008
    ..In the ED group (early death, n = 3), the cloned cattle died in the perinatal period. The cattle in the LD group (late death, n = 3) died after the perinatal period. Normally reproduced cattle served as a control group (n = 3)...
  5. doi request reprint Identification and characterization of a cathepsin-L-like peptidase in Eimeria tenella
    Renqiang Liu
    National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, No 2 Yuan Ming Yuan West Road, Haidian District, Beijing, 100193, China
    Parasitol Res 113:4335-48. 2014
    ..6 and 15.5% that of control chickens. These results indicate that the EtcatL can be used as an effective immunogen, and further studies are needed to enhance its potential as a vaccine candidate molecule...
  6. ncbi request reprint Expression of insulin-like growth factors systems in cloned cattle dead within hours after birth
    Shijie Li
    The State Key Laboratory for Agrobiotechnology in Livestock and Poultry, China Agricultural University, Beijing, China
    Mol Reprod Dev 74:397-402. 2007
    ..Because IGF systems play an important role in embryo development and organogenesis, the aberrant transcription patterns detected in these clones may contribute to the defects of organs reported in neonatal death of clones...
  7. doi request reprint Impacts of human lysozyme transgene on the microflora of pig feces and the surrounding soil
    Jie Zhao
    State Key Laboratory for Agrobiotechnology, College of Biological Science, China Agricultural University, Haidian District, Beijing 100193, People s Republic of China
    J Biotechnol 161:437-44. 2012
    ..Finally, TN and TP contents were not significantly different in pig manure or soils taken at different distances from the pig site (P>0.25)...
  8. ncbi request reprint Birth of calves expressing the enhanced green fluorescent protein after transfer of fresh or vitrified/thawed blastocysts produced by somatic cell nuclear transfer
    Guochun Gong
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
    Mol Reprod Dev 69:278-88. 2004
    ..Our results show that genetic manipulation and serum starvation of donor cells (FOECs) do not affect in vitro developmental competence of bovine SCNT embryos, and vitrified transgenic SCNT blastocysts can develop to term successfully...
  9. doi request reprint Eimeria tenella: interleukin 17 contributes to host immunopathology in the gut during experimental infection
    Lei Zhang
    National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100193, China
    Exp Parasitol 133:121-30. 2013
    ..These results suggested that chicken IL-17 might mediate E. tenella - induced immunopathology during the infection...
  10. pmc The role of neoadjuvant chemotherapy for resectable colorectal liver metastases: a systematic review and meta-analysis
    Wei Liu
    Hepatopancreatobiliary Surgery Department I, Key laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, PR China
    Oncotarget 7:37277-37287. 2016
    ..69 (95% CI: 0.55-0.87; p=0.00; I2=0.0%, p=0.48). These results suggest neoadjuvant chemotherapy improved survival of patients with initially resectable CRLM and a high risk of disease recurrence...
  11. pmc Inequities and psychiatry disability in transition among the elderly population from 1987 to 2006 in China: Data based on national surveys
    Zhenjie Wang
    aInstitute of Population Research WHO Collaborating Center on Reproductive Health and Population Science bLaboratory of Neuroscience and Mental Health, Peking University, Haidian District, Beijing, People s Republic of China
    Medicine (Baltimore) 95:e4779. 2016
    ..These associations remained even after these 2 surveys were combined.The rapidly rising prevalence of psychiatric disorders expected warrants strategies to reduce the burden of these disabilities among females and rural residents. ..
  12. pmc Genome-wide association study identifies Loci and candidate genes for body composition and meat quality traits in Beijing-You chickens
    Ranran Liu
    Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, PR China
    PLoS ONE 8:e61172. 2013
    ..For meat quality traits, several SNPs reaching suggestive association were identified and possible candidate genes with their functions were discussed...
  13. doi request reprint MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation
    Jianli Xu
    Department of Orthopaedic Surgery, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, PR China
    Biomed Pharmacother 67:381-6. 2013
    ..We concluded that miR-223 functions as a tumor suppresser in osteosarcoma and miR-223/Ect2/p21 signaling is an important pathway that regulates the osteosarcoma cell cycle progression and proliferaion...
  14. pmc Expressional analysis of immunoglobulin D in cattle (Bos taurus), a large domesticated ungulate
    Beilei Xu
    State Key Laboratory of Agrobiotechnology, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing, PR China
    PLoS ONE 7:e44719. 2012
    ..This study has answered a long-standing question in cattle B cell biology and significantly contributes to our understanding of B cell development in this species...
  15. doi request reprint Comprehensive characterization of the site-specific N-glycosylation of wild-type and recombinant human lactoferrin expressed in the milk of transgenic cloned cattle
    Tian Yu
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, People s Republic of China
    Glycobiology 21:206-24. 2011
    ..These data provide an important foundation for further studies of glycan structure/function relationships for hLF and rhLF and help to better understand the glycosylation mechanism in bovine mammary epithelial cells...