Jing Wu

Summary

Country: China

Publications

  1. ncbi Childhood gynecomastia: a clinical analysis of 240 cases
    Rui zhen Li
    Department of Pediatrics, Tongji Hospital, Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China
    Zhongguo Dang Dai Er Ke Za Zhi 9:404-6. 2007
  2. ncbi Translocation and phosphorylation of calcyclin binding protein during retinoic acid-induced neuronal differentiation of neuroblastoma SH-SY5Y cells
    Jing Wu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Science, Chinese Academy of Medical Sciences and Peking Union Medical College, National Human Genome Center, Beijing 100005, China
    J Biochem Mol Biol 36:354-8. 2003
  3. ncbi Detection and genotyping of human papillomavirus DNA in cervical cancer tissues with fluorescence polarization
    Yan e Gao
    Department of Obstetrics and Gynecology, Second Hospital, Xi an Jiaotong University, Xi an 710004, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:1029-34. 2003
  4. ncbi dPattern: transcription factor binding site (TFBS) discovery in human genome using a discriminative pattern analysis
    Seung Hee Bae
    Department of Computer Science, Indiana University Bloomington, IN 47404, USA
    Bioinformatics 23:2619-21. 2007
  5. pmc LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling
    Yijun Gao
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China
    Proc Natl Acad Sci U S A 107:18892-7. 2010
  6. pmc Peritoneal metastatic adenocarcinoma possibly due to a gastric duplication cyst: a case report and literature review
    Kuiliang Liu
    Gastroenterology Department, Beijing Shijitan Hospital, Capital Medical University, NO, 10 Tieyi Road, Haidian, Beijing 100038, People s Republic of China
    BMC Gastroenterol 14:48. 2014
  7. doi The mechanisms of 5-FU-PLA-O-CMC-NPS-mediated inhibition of the proliferation of colorectal cancer cell line SW480
    Jing Wu
    Department of Gastroenterology and Hepatology, Beijing Shi Ji Tan Hospital of Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, China, 100038
    Tumour Biol 35:6095-103. 2014
  8. pmc Effect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell line
    Jing Wu
    Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Gansu Province, China
    World J Gastroenterol 10:3380-1. 2004
  9. ncbi Effects of {2-[(3-carboxy-1-oxoprogy1)amino]-2-deoxy-D-glucose} on human hepatocellular carcinoma cell line
    Jing Wu
    Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China
    Acta Pharmacol Sin 26:635-40. 2005
  10. doi Proteomic analysis of skin defensive factors of tree frog Hyla simplex
    Jing Wu
    Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    J Proteome Res 10:4230-40. 2011

Collaborators

Detail Information

Publications91

  1. ncbi Childhood gynecomastia: a clinical analysis of 240 cases
    Rui zhen Li
    Department of Pediatrics, Tongji Hospital, Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China
    Zhongguo Dang Dai Er Ke Za Zhi 9:404-6. 2007
    ..The 219 cases of adolescent breast hyperplasia and 14 cases of idiopathic gynecomastia were not given any medication. They were followed up regularly. Most of the patients recovered well within a 27-month follow-up...
  2. ncbi Translocation and phosphorylation of calcyclin binding protein during retinoic acid-induced neuronal differentiation of neuroblastoma SH-SY5Y cells
    Jing Wu
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Science, Chinese Academy of Medical Sciences and Peking Union Medical College, National Human Genome Center, Beijing 100005, China
    J Biochem Mol Biol 36:354-8. 2003
    ..The translocation of CacyBP during the RA-induced differentiation of SH-SY5Y cells suggested that this protein might play a role in neuronal differentiation...
  3. ncbi Detection and genotyping of human papillomavirus DNA in cervical cancer tissues with fluorescence polarization
    Yan e Gao
    Department of Obstetrics and Gynecology, Second Hospital, Xi an Jiaotong University, Xi an 710004, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:1029-34. 2003
    ..The high prevalence of HPV 58 in Chinese women should been considered in diagnosis and vaccine designs of HPV...
  4. ncbi dPattern: transcription factor binding site (TFBS) discovery in human genome using a discriminative pattern analysis
    Seung Hee Bae
    Department of Computer Science, Indiana University Bloomington, IN 47404, USA
    Bioinformatics 23:2619-21. 2007
    ..When combined with additional information, gene expression data in this article, sensitivity and specificity of TFBS search can be improved significantly...
  5. pmc LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling
    Yijun Gao
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China
    Proc Natl Acad Sci U S A 107:18892-7. 2010
    ..Our findings provide evidence of how LKB1 loss of function promotes lung cancer malignancy through remodeling of extracellular matrix microenvironment, and identify LOX as a potential target for disease treatment in lung cancer patients...
  6. pmc Peritoneal metastatic adenocarcinoma possibly due to a gastric duplication cyst: a case report and literature review
    Kuiliang Liu
    Gastroenterology Department, Beijing Shijitan Hospital, Capital Medical University, NO, 10 Tieyi Road, Haidian, Beijing 100038, People s Republic of China
    BMC Gastroenterol 14:48. 2014
    ..Gastric duplication cysts are rare congenital abnormalities, and malignant transformation of these duplications is also thought to be rare...
  7. doi The mechanisms of 5-FU-PLA-O-CMC-NPS-mediated inhibition of the proliferation of colorectal cancer cell line SW480
    Jing Wu
    Department of Gastroenterology and Hepatology, Beijing Shi Ji Tan Hospital of Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, China, 100038
    Tumour Biol 35:6095-103. 2014
    ..We concluded that 5-FPOCN can significantly inhibit the growth of colon cancer SW480 cells. 5-FPOCN increased P21 expression and decreased cyclin family and pRb expression to promote cell cycle delay and apoptosis...
  8. pmc Effect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell line
    Jing Wu
    Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Gansu Province, China
    World J Gastroenterol 10:3380-1. 2004
    ..To determine whether 2-(3-carboxy-1-oxopropy1) amino-2-deoxy-D-glucose (COPADG), a derivative of D-amino-glucose, inhibited the growth of human esophageal cancer cell line Eca-109...
  9. ncbi Effects of {2-[(3-carboxy-1-oxoprogy1)amino]-2-deoxy-D-glucose} on human hepatocellular carcinoma cell line
    Jing Wu
    Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China
    Acta Pharmacol Sin 26:635-40. 2005
    ..To study the effects of {2-[(3-carboxy-1-oxoprogy1)amino]-2-deoxy-D-glucose (COPADG) on cultured human hepatocellular carcinoma cells (HepG2)...
  10. doi Proteomic analysis of skin defensive factors of tree frog Hyla simplex
    Jing Wu
    Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    J Proteome Res 10:4230-40. 2011
    ..The chemical array in the tree frog skin shares some similarities with snake venoms. Most of these components in this tree frog help defend against predators, heal wounds, or attenuate suffering...
  11. doi Frog skins keep redox homeostasis by antioxidant peptides with rapid radical scavenging ability
    Cunbao Liu
    Biotoxin Unit of the Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Free Radic Biol Med 48:1173-81. 2010
    ..Cys10 is proven to be responsible for its rapid radical scavenging function and tyrosines take part in the binding of antioxidin-RL to radicals according to our nuclear magnetic resonance assay...
  12. doi Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands
    Jing Wu
    Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China
    J Org Chem 78:5611-7. 2013
    ..The desired products were obtained in up to 99% yield with 96% ee...
  13. doi {2-[(3-Carboxy-1-oxopropyl) amino]-2-deoxy-D-Glucose} suppresses proliferation and induces apoptosis in the human esophageal cancer cell line
    Jing Wu
    Department of Gastroenterology and Hepatology, Beijing Shijitan Hospital, Beijing, 100038, China
    Med Oncol 28:986-90. 2011
    ....
  14. doi Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice
    Jing Wu
    Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Cardiovascular Science of the Ministry of Education, Beijing, China
    Hepatology 58:617-28. 2013
    ..Moreover, deletion of the SRE site completely abolished SREBP-1c-induced Thrsp transcription...
  15. ncbi 2-[(3-carboxy-1-oxoprogy1) amino]-2-deoxy-D-glucose induces apoptosis in Hep G2 cells
    Jing Wu
    Department of Gastroenterology and Hepatology, the First Hospital of Lanzhou University, Lanzhou 730000, China
    Exp Oncol 27:52-5. 2005
    ..To determine the effect of 2-[(3-carboxy-1-oxoprogy1) amino]-2-deoxy-D-glucose (COPADG) on proliferation and apoptosis of human hepatocellular carcinoma cells (Hep G2)...
  16. doi Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway
    Jing Li
    Department of Physiology and Pathophysiology, Beijing, China
    Hepatology 53:1906-16. 2011
    ..Moreover, FOXO1 overexpression increased PANDER expression in cultured hepatocytes and mouse livers...
  17. pmc Two immunoregulatory peptides with antioxidant activity from tick salivary glands
    Jing Wu
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    J Biol Chem 285:16606-13. 2010
    ..These results showed that immunoregulatory peptides of tick salivary glands suppress host inflammatory response by modulating cytokine secretion and detoxifying reactive oxygen species...
  18. doi Effectiveness of systematic training in the application of narrow-band imaging international colorectal endoscopic (NICE) classification for optical diagnosis of colorectal polyps: Experience from a single center in China
    Yinhe Sikong
    Department of Gastroenterology, Beijing Shijitan Hospital Capital Medical University, Beijing, China
    Dig Endosc 28:583-91. 2016
    ..To evaluate the effectiveness of systematic training in the application of narrow-band imaging (NBI) International Colorectal Endoscopic (NICE) classification for the prediction of the histology of colorectal polyps...
  19. doi Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism
    Xiaoyan Zhang
    Department of Pediatrics, Peking University First Hospital, Beijing, China Shenzhen University Diabetes Center, Shenzhen University Health Science Center, Shenzhen, China
    J Diabetes 6:212-20. 2014
    ..The liver is the central organ in controlling lipid metabolism. In the present study, we aimed at elucidating the role of LXR activation in hepatic fatty acid homeostasis...
  20. pmc Interaction between cyclooxygenase-2, Snail, and E-cadherin in gastric cancer cells
    Xiao Jun Liu
    Xiao Jun Liu, Zhao Feng Chen, Hai Long Li, Ze Nan Hu, Ai Ping Tian, Da Zhao, Yong Ning Zhou, Liang Qiao, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
    World J Gastroenterol 19:6265-71. 2013
    ..To investigate the mechanisms of how cyclooxygenase-2 (COX-2) regulates E-cadherin in gastric cancer cells...
  21. doi Targeted isolation and analysis of single tumor cells with aptamer-encoded microwell array on microfluidic device
    Qiushui Chen
    Beijing Key Laboratory of Microanalytical Method and Instrumentation, Department of Chemistry, Tsinghua University, Beijing, 100084, China
    Lab Chip 12:5180-5. 2012
    ..Thus, our technique will open up a new opportunity in single-cell level-based disease diagnosis and personalize medicine screening...
  22. pmc A bi-functional anti-thrombosis protein containing both direct-acting fibrin(ogen)olytic and plasminogen-activating activities
    Hailong Yang
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    PLoS ONE 6:e17519. 2011
    ..Currently, we have identified a fibrin(ogen)olytic protein (Eupolytin1) containing both fibrin(ogen)olytic and plasminogen-activating (PA) activities from the beetle, E. sinensis...
  23. ncbi [The derivative of D-amine-glucose induced apoptosis in hepatocellular carcinoma cells]
    Jing Wu
    Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China
    Zhonghua Gan Zang Bing Za Zhi 12:697. 2004
  24. doi Facile synthesis of 5H-benzo[b]carbazol-6-yl ketones via sequential reaction of Cu-catalyzed Friedel-Crafts alkylation, iodine-promoted cyclization, nucleophilic substitution and aromatization
    Jing Wu
    Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
    Org Biomol Chem 12:6806-11. 2014
    ..The products of the functional 5H-benzo[b]carbazol-6-yl ketones were obtained with up to 98% yield. ..
  25. doi Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer
    Yongning Zhou
    Division of Gastroenterology and Hepatology, the First Hospital of Lanzhou University, Gansu Province, Lanzhou 730000, China
    Tumour Biol 31:549-58. 2010
    ..Positive expression of E-cadherin and negative expression of VEGF and MMP-2 are correlated with a better patient survival...
  26. doi Effect of silent mutations in Translational Initial Region on the production of recombinant cutinase in Escherichia coli
    Zhi Guo Liu
    State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Ave, Wuxi, Jiangsu 214122, China
    Curr Microbiol 62:1302-7. 2011
    ..0 U/ml was achieved, which is three times that of the control group. This study explored the potential utilization of TIR degeneracy mutagenesis in the production of industrial enzymes...
  27. ncbi [Construction of infectious molecular clone of duck hepatitis virus type 1 CL strain]
    Kexiang Yu
    Institute of Poultry, Shandong Academy of Agricultural Sciences, Key Laboratory of Poultry Disease Diagnose and Immune of Shandong Province, Jinan 250023, China
    Wei Sheng Wu Xue Bao 49:1650-4. 2009
    ..To construct an infectious clone for studying functions of duck hepatitis virus (DHV) typel genome by reverse genetic technique...
  28. ncbi [Small interfering RNA (siRNA) targeting vascular endothelial growth factor inhibits vascular leakage in brain of rats exposed to high altitude]
    Zhi kuan Deng
    Department of Neurology, Second Affiliated Hospital, Third Military Medical University, Chongqing 400037, China
    Zhonghua Yi Xue Za Zhi 89:2639-43. 2009
    ....
  29. ncbi [Coadministration of sorafenib and cisplatin inhibits proliferation of hepatocellular carcinoma HepG2 cells in vitro]
    Feng sheng Chen
    Oncology Center, Nanfang Hospital, Southern Medical Unversity, Guangzhou, China
    Nan Fang Yi Ke Da Xue Xue Bao 28:1684-7. 2008
    ..To investigate the inhibitory effect of sorafenib in combination with cisplatin (DDP) on the proliferation of hepatocellular carcinoma cells and explore the molecular mechanisms...
  30. ncbi [Application of ultrathin transnasal gastroscopy in percutaneous endoscopic gastrostomy]
    Xue Qing Chen
    Department of Gastroenterology, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China
    Nan Fang Yi Ke Da Xue Xue Bao 29:121-3. 2009
    ..To assess the application of ultrathin transnasal gastroscopy in transnasal percutaneous endoscopic gastrostomy (nPEG) in patients with trimus and/or pharyngeal narrowing...
  31. ncbi [HBVcccDNA of patients with hepatitis B in the serum, PBMC and liver tissue distribution]
    Yong le Zhang
    The Sixth People s Hospital of Hangzhou Affiliated to Zhejiang Chinese Medial University, Hangzhou 310014, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 22:342-4. 2008
    ..Hepatitis B virus covalently closed circular DNA in the serum of patients with hepatitis B, peripheral mononuclear cells (PBMC) and liver tissue distribution...
  32. ncbi [Genetic polymorphisms of fifteen short tandem repeat loci in Chengdu Han population]
    Yingbi Li
    School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:169-73. 2005
    ..To acquire the population genetic data of fifteen short tandem repeat (STR) loci in Chengdu Han population...
  33. ncbi [The STR typing system by fluorescence labeled Multiplex-PCR technique and its forensic application]
    Ying Bi Li
    School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu 610041, China
    Fa Yi Xue Za Zhi 21:96-9. 2005
    ..To build the four STR loci typing system by fluorescence labeled Multiplex-PCR technique, applied in the parentage test and personal identification in forensic medicine...
  34. doi The clinical analysis of 34 cases of intestinal tuberculosis in China's big city hospitals
    Wei Ping Tai
    Department of Gastroenterology, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China
    Int J Colorectal Dis 26:1339-43. 2011
    ..Intestinal tuberculosis is not uncommon in developing countries. The diagnosis of this disease is quite difficult. The purpose of our research was to recall the clinical, colonoscopic, and histopathological features of this disease...
  35. ncbi [Celecoxib induces apoptosis and inhibits angiogenesis in gastric cancer]
    Jun Tao Ran
    Department of Gastroenterology, The First Hospital, Lanzhou University, Lanzhou 730000, China
    Zhonghua Zhong Liu Za Zhi 30:448-51. 2008
    ..The aim of this study was to explore the effect of celecoxib, a cyclooxygenase-2 inhibitor, on induction of apoptosis and inhibition of angiogenesis in gastric cancer...
  36. pmc Flexible control of cellular encapsulation, permeability, and release in a droplet-templated bifunctional copolymer scaffold
    Qiushui Chen
    Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, Tsinghua University, Beijing, China
    Biomicrofluidics 10:064115. 2016
    ..Subsequently, we demonstrate a high viability of microencapsulated cells in the microgel scaffolds...
  37. pmc Comprehensive analysis and discovery of drought-related NAC transcription factors in common bean
    Jing Wu
    Key Laboratory of Crop Germplasm Resources and Utilization, Ministry of Agriculture, The National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Science, The Chinese Academy of Agricultural Sciences, Beijing, 100081, China
    BMC Plant Biol 16:193. 2016
    ..The NAM, ATAF1/2 and CUC2 (NAC) domain protein family are classic transcription factors (TFs) involved in a variety of abiotic stresses, particularly drought stress. However, the NAC TFs in common bean have not been characterized...
  38. doi Induction of MIF expression by oxidized LDL via activation of NF-kappaB in vascular smooth muscle cells
    Lihong Chen
    Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China
    Atherosclerosis 207:428-33. 2009
    ..Taken together, our results revealed that MIF expression can be induced by oxLDL in VSMCs via a NF-kappaB dependent manner, which may contribute to the pathogenesis of atherosclerosis...
  39. pmc Differential protein expression in honeybee (Apis mellifera L.) larvae: underlying caste differentiation
    Jianke Li
    Key Laboratory of Pollinating Insect Biology, Department of Beekeeping and Biotechnology, Ministry of Agriculture, Institute of Apicultural Research, Chinese Academy of Agricultural Science, Beijing, China
    PLoS ONE 5:e13455. 2010
    ....
  40. ncbi Antimicrobial activity of linezolid combined with minocycline against vancomycin-resistant Enterococci
    Jing Wu
    Department of Clinical Laboratory, First Hospital of Fangshan District, Beijing, China
    Chin Med J (Engl) 126:2670-5. 2013
    ....
  41. pmc Variations in lead isotopic abundances in Sprague-Dawley rat tissues: possible reason of formation
    Duojian Liu
    School of Public Health, Peking University, Haidian District, Beijing, People s Republic of China
    PLoS ONE 9:e89805. 2014
    ..When the whole-blood level is higher than 50 ng/mL, the lead isotopic compositions of biological samples tend to be the same. Thus, the data support the speculation of a fractionation functional threshold. ..
  42. doi An economical fluorescence detector for lab-on-a-chip devices with a light emitting photodiode and a low-cost avalanche photodiode
    Jing Wu
    Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization, Gansu Province, Department of Chemistry, Lanzhou University, 222 Southern Tianshui Road, Lanzhou, 730000, China
    Analyst 137:519-25. 2012
    ..The aim of the work is to prove that widely available, low-cost components for civilian use can be successfully used for miniaturized analytical devices...
  43. pmc Mapping and Genetic Structure Analysis of the Anthracnose Resistance Locus Co-1HY in the Common Bean (Phaseolus vulgaris L.)
    Mingli Chen
    Key Laboratory of Crop Germplasm Resources and Utilization, Ministry of Agriculture The National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Science, The Chinese Academy of Agricultural Sciences, Beijing, China
    PLoS ONE 12:e0169954. 2017
    ..The closely linked flanking markers identified here may be useful for transferring the resistance allele Co-1HY from Hongyundou to elite anthracnose susceptible common bean lines...
  44. pmc Doxorubicin nanobubble for combining ultrasonography and targeted chemotherapy of rabbit with VX2 liver tumor
    Mingming Meng
    The Department of Gastroenterology, Beijing Shijitan Hospital, Capital Medical University, 10 Tieyi Road, Yangfang District, Beijing, 100038, China
    Tumour Biol 37:8673-80. 2016
    ..Ultrasound combined with DOX-NB had significant antitumor effect. Compared with other groups, the tumor growth rate and the proliferation index were the lowest while the survival rate and apoptosis index were the highest. ..
  45. doi Multi-channel cell co-culture for drug development based on glass microfluidic chip-mass spectrometry coupled platform
    Jing Wu
    School of Science, China University of Geosciences Beijing, Beijing, 100083, China
    Rapid Commun Mass Spectrom 30:80-6. 2016
    ..Cell co-culture, cell apoptosis assay, fluorescence and MS detection of intracellular drug absorption could be simultaneously conducted on this platform...
  46. ncbi Comparison of chemical compositions in air particulate matter during summer and winter in Beijing, China
    Rui Chen
    Department of Municipal and Environmental Engineering, School of Civil Engineering, Beijing Jiaotong University, Beijing, 100044, China
    Environ Geochem Health . 2016
    ..Chemical Mass Balance model revealed central heating activities, road dust and vehicles contribute as main sources, account for 5.84-32.05 % differently to the summer and winter air pollution in 2014...
  47. pmc miR-24-3p Regulates Progression of Gastric Mucosal Lesions and Suppresses Proliferation and Invasiveness of N87 Via Peroxiredoxin 6
    Qian Li
    Department of Gastroenterology, Peking University Ninth School of Clinical Medicine, Beijing, China
    Dig Dis Sci 61:3486-3497. 2016
    ..MicroRNAs, targeting mRNAs of cancer-associated genes, are often aberrantly expressed in human gastric cancer (GC)...
  48. doi ZnO nanowire arrays exhibit cytotoxic distinction to cancer cells with different surface charge density: cytotoxicity is charge-dependent
    Ruizhi Ning
    State Key Laboratory of Chemical Resource Engineering, Beijing Key Laboratory of Electrochemical Process and Technology for Materials, Beijing University of Chemical Technology, Beijing, 100029, P R China Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, Tsinghua University, Beijing, 100084, P R China
    Small 10:4113-7. 2014
    ....
  49. doi Evaluating the diagnoses of gastric antral lesions using magnifying endoscopy with narrow-band imaging in a Chinese population
    Hong Liu
    Department of Gastroenterology, Beijing Shijitan Hospital, Capital Medical University, No 10, Tieyi Road, Beijing, 100038, China
    Dig Dis Sci 59:1513-9. 2014
    ..To evaluate the accuracy of diagnosing gastric antral lesions in routine clinical practice using magnifying endoscopy with narrow-band imaging (M-NBI) as a real-time diagnosing technique...
  50. doi No association between XRCC1 polymorphisms and survival in non-small-cell lung cancer patients treated with platinum-based chemotherapy
    Peng Yuan
    Department of Medical Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
    Cancer Biol Ther 10:854-9. 2010
    ....
  51. doi Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes
    Dongjuan Zhang
    Dept of Physiology and Pathophysiology, Peking University Health Science Ctr, Haidian District, Beijing, China
    Am J Physiol Endocrinol Metab 300:E287-95. 2011
    ..Enhanced ketone body production in the diabetic kidney may represent a novel mechanism involved in the pathogenesis of DN...
  52. pmc A novel missense SNRNP200 mutation associated with autosomal dominant retinitis pigmentosa in a Chinese family
    Tiecheng Liu
    Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China
    PLoS ONE 7:e45464. 2012
    ....
  53. doi Six ulcerative colitis patients with refractory symptoms co-infective with Blastocystis hominis in China
    Wei Ping Tai
    Department of Gastroenterology, Beijing Shijitan Hospital, Beijing, 100038, China
    Parasitol Res 108:1207-10. 2011
    ..They almost completely recovered 3 weeks later. Patients diagnosed with ulcerative colitis should always consider this parasite infection when the symptoms are refractory and cannot be released...
  54. doi Cytotoxicity of quantum dots assay on a microfluidic 3D-culture device based on modeling diffusion process between blood vessels and tissues
    Jing Wu
    Beijing Key Laboratory of Microanalytical Method and Instrumentation, Department of Chemistry, Tsinghua University, Beijing, 100084, China
    Lab Chip 12:3474-80. 2012
    ..The device shows potential as a high-throughput, low-cost and time-saving platform and constructs a more vivid biomimetic microenvironment for the QD cytotoxicity study...
  55. pmc The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers
    Jiansheng Wang
    Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China, 100038
    BMC Cancer 12:418. 2012
    ..The role of Th17 cells in colorectal tumorigenesis and development still remains unclear, despite the fact that it has been established in the pathogenesis of autoimmune diseases...
  56. doi Genome-wide analysis of genes associated with moderate and high DDT resistance in Drosophila melanogaster
    Xinghui Qiu
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Pest Manag Sci 69:930-7. 2013
    ..The presence of common regulatory motifs among resistance-associated genes may help to explain how and why certain suites of genes are preferentially represented in genomic-scale analyses...
  57. pmc Biological fractionation of lead isotopes in Sprague-Dawley rats lead poisoned via the respiratory tract
    Jing Wu
    School of Public Health, Peking University, Haidian District, Beijing, People s Republic of China
    PLoS ONE 7:e52462. 2012
    ..An animal experiment was conducted to explore the biological fractionation of lead isotopes in biological systems...
  58. pmc Smooth muscle protein 22 alpha-Cre is expressed in myeloid cells in mice
    Zhuxia Shen
    Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Clinical Research Center of Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Biochem Biophys Res Commun 422:639-42. 2012
    ..Therefore, accurate determination of Cre activity is critical to the interpretation of experiments using smooth muscle specific Cre...
  59. doi The use of ethylene glycol solution as the running buffer for highly efficient microchip-based electrophoresis in unmodified cyclic olefin copolymer microchips
    Qin Wang
    Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization, Gansu Province, Sate Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, 222 Southern Tianshui Road, Lanzhou, Gansu 730000, China
    J Chromatogr A 1218:9422-7. 2011
    ..4% and 0.7%, respectively. Furthermore, the system was successfully applied to elucidate these five amino acids in human saliva...
  60. doi A new type of bis(sulfonamide)-diamine ligand for a Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with nitroalkenes
    Jing Wu
    Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China
    Org Lett 13:4834-7. 2011
    ..Chiral bis(sulfonamide)-diamine served as new type of ligand for a Cu(OTf)(2)-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with nitroalkenes. The desired products were obtained with up to 99% yield and 97% ee...
  61. doi Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata
    Yufang Ma
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Genomics 95:66-71. 2010
    ..Some AMPs reported here will provide leading molecules for designing novel antimicrobial agents...
  62. doi A horsefly saliva antigen 5-like protein containing RTS motif is an angiogenesis inhibitor
    Dongying Ma
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 JiaoChangDongLu, Kunming 650223, Yunnan, China
    Toxicon 55:45-51. 2010
    ..The current work revealed the first angiogenesis inhibitor protein containing RTS motif from invertebrates, a possible novel type of RTS-disintegrin...
  63. ncbi Anti-infection peptidomics of amphibian skin
    Jianxu Li
    Biotoxin Units and gLaboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Mol Cell Proteomics 6:882-94. 2007
    ..With respect to the development of antibiotics, these peptides provide potential new templates to explore further...
  64. ncbi Toward an understanding of the molecular mechanism for successful blood feeding by coupling proteomics analysis with pharmacological testing of horsefly salivary glands
    Xueqing Xu
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Mol Cell Proteomics 7:582-90. 2008
    ..The current work will facilitate the understanding of the molecular mechanisms of the ectoparasite-host relationship and help in identifying novel vaccine targets and novel leading pharmacological compounds...
  65. doi Two serine protease inhibitors from the skin secretions of the toad, Bombina microdeladigitora
    Xiangyun Lu
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Comp Biochem Physiol B Biochem Mol Biol 149:608-12. 2008
    ..02 microM and 0.15 microM, respectively. Sequence analysis revealed that all serine protease inhibitors from five amphibians of the genus Bombina share highly conserved primary structures...
  66. doi A rising trend of gastric cardia cancer in Gansu Province of China
    Yongning Zhou
    Division of Gastroenterology and Hepatology, the First Hospital of Lanzhou University, Gansu Province, China
    Cancer Lett 269:18-25. 2008
    ..Thus, there was a rising trend of cardia cancers and a decreasing trend of most non-cardia cancers...
  67. pmc Anti-thrombosis repertoire of blood-feeding horsefly salivary glands
    Dongying Ma
    Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Mol Cell Proteomics 8:2071-9. 2009
    ..The extreme diversity of horsefly anti-thrombosis components also reveals the anti-thrombosis molecular mechanisms of the traditional Eastern medicine insect material...
  68. pmc The first gene-encoded amphibian neurotoxin
    Dewen You
    Biotoxin Unit of Key Laboratory of Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    J Biol Chem 284:22079-86. 2009
    ..The tissue distribution and functional properties of the current toxin may provide insights into the ecological adaptation of tree-living amphibians...
  69. ncbi Augmentation of antitumor effects of p53 gene therapy by combination with HDAC inhibitor
    Rishu Takimoto
    Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
    Cancer Biol Ther 4:421-8. 2005
    ..Thus SB was shown to be an efficient potentiator of p53 gene therapy for cancer...
  70. ncbi Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma
    Enyu Liu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University Neurosurgical Institute of Chinese PLA, Xian, PR China
    J Neurooncol 85:263-70. 2007
    ....
  71. ncbi Allele frequencies for three STR loci D1S3465, D6S2433 and D10S2481 in Chinese population
    Haijun Zhang
    Institute of Forensic Medicine, Sichuan University West China University of Medical Sciences, Chengdu 610041, Sichuan, PR China
    J Forensic Sci 50:974. 2005
  72. ncbi Haplotype of 12 Y-STR loci of the PowerPlex Y-system in Sichuan Han ethnic group in west China
    Haijun Zhang
    Institute of Forensic Medicine, Sichuan University West China University of Medical Sciences, Chengdu 610041, Sichuan, PR China
    Forensic Sci Int 175:244-9. 2008
    ..Twelve of the haplotypes were encountered in duplicate, while 210 haplotypes were unique. The gene diversity was 0.9952. This study provides an essential precondition for identification of male DNA and tracing of paternal lineages...
  73. ncbi Analysis of 15 STR loci in Chinese population from Sichuan in West China
    Haijun Zhang
    Institute of Forensic Medicine, Sichuan University West China University of Medical Sciences, Chengdu 610041, Sichuan, PR China
    Forensic Sci Int 171:222-5. 2007
    ..All loci were in accordance with Hardy-Weinberg equilibrium (p<0.05). The obtained frequency distributions were compared with other previously reported population data...
  74. pmc Association of FAS (TNFRSF6)-670 gene polymorphism with villous atrophy in coeliac disease
    Jing Wu
    VU University Medical Centre, Department of Gastroenterology, Laboratory of Immunogenetics, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    World J Gastroenterol 10:717-20. 2004
    ..To investigate the association of FAS gene polymorphism with coeliac disease (CD) development...
  75. ncbi Expression, crystallization and preliminary X-ray studies of the recombinant PTB domain of mouse dok1 protein
    Ning Shi
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, National Human Genome Center, Beijing 100005, People s Republic of China
    Acta Crystallogr D Biol Crystallogr 60:334-6. 2004
    ..Subsequently, three different wavelength data sets from the derivative crystal were collected to 2.5 A resolution at SPring-8...
  76. pmc GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
    Jeffrey A Grass
    Molecular and Cellular Pharmacology Program, Department of Pharmacology, University of Wisconsin Medical School, 383 Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 100:8811-6. 2003
    ..Such a mechanism is predicted to be critical for the control of hematopoiesis...
  77. ncbi 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer
    Jing Wu
    Department of Medicine, University of Hong Kong, Hong Kong, P R China
    Carcinogenesis 24:243-7. 2003
    ..These findings demonstrated that SC-236 induced apoptosis in gastric cancer cells via up-regulation of 15-LOX-1, and 13-S-HODE. These are potential and new targets for prevention and treatment of gastric cancer...
  78. ncbi [PIV: a computer-aided portal image verification system]
    Weihua Fu
    Department of Radiotherapy Oncology, Cancer Institute Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 19:664-6. 2002
    ..Semi-automatic register methods make verification more accurate than view-box method. It can provide useful quantitative errors for regular fields. PIV is flexible and accurate. It is an effective tool for portal field verification...
  79. pmc Angiostatin up-regulation in gastric cancer cell SGC7901 inhibits tumorigenesis in nude mice
    Jing Wu
    Institute of Gastrointestinal Diseases Research, Xijing Hospital, Fourth Military Medical University, Xi an 710032, Shannxi Province, China
    World J Gastroenterol 9:59-64. 2003
    ..To explore the influence of angiostatin up-regulation on the biologic behavior of gastric cancer cells in vitro and in vivo, and the potential of angiostatin gene therapy in the treatment of human gastric cancer...
  80. ncbi Use of zoledronate to treat osteoblastic versus osteolytic lesions in a severe-combined-immunodeficient mouse model
    Yu Po Lee
    Department of Orthopaedic Surgery, David Geffen School of Medicine, Los Angeles, California 90095, USA
    Cancer Res 62:5564-70. 2002
    ..Hence, bisphosphonates may not be ideal agents to prevent the formation of osteoblastic lesions associated with prostate cancer metastases to bone...
  81. ncbi Polymorphism of the leptin gene promoter in pedigrees of type 2 diabetes mellitus in Chongqing, China
    Wei Ren
    Department of Endocrinology, First Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400016, China
    Chin Med J (Engl) 117:558-61. 2004
    ..In this research, we evaluated the presence of the leptin C-2549-A polymorphism in the Chinese population in Chongqing and verified its association with plasma leptin levels and anthropometric, metabolic, and clinical parameters...
  82. ncbi [Quantitation of human telomerase reverse transcriptase mRNA with real-time fluorescent RT-PCR]
    Ying Guo
    Department of Obstetrics and Gynecology, Second Hospital of Xi an Jiaotong University, Xi an 710001, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:618-20. 2004
    ..To establish a real-time fluorescent RT-PCR assay to quantify human telomerase reverse transcriptase (hTERT) mRNA...
  83. ncbi Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation
    Hogune Im
    Department of Pharmacology, Molecular and Cellular Pharmacology Program, University of Wisconsin Medical School, Madison, USA
    Methods Mol Biol 284:129-46. 2004
    ..Chromatin-domain scanning coupled with quantitative analysis is a powerful means of dissecting mechanisms by which signaling pathways target genes within a complex genome...
  84. ncbi Screening cellular proteins involved in the anti-proliferative effect of the ADAM15 disintegrin domain in murine melanoma cells
    Jing Wu
    School of Medicine and Pharmaceutics, Ministry of Education, Jiangnan University, Jiangsu, P R China
    Oncol Rep 20:669-75. 2008
    ..These results provide evidence that RADD inhibits melanoma cell proliferation partly through p38 kinase activation...
  85. pmc Phase studies of model biomembranes: complex behavior of DSPC/DOPC/cholesterol
    Jiang Zhao
    Field of Biophysics, Cornell University, Ithaca, NY 14853, USA
    Biochim Biophys Acta 1768:2764-76. 2007
    ..Measurements of the perturbations of the boundaries of this accurate phase diagram could serve as a means to understand the behaviors of a range of added lipids and proteins...
  86. ncbi Characterization of glucose-6-phosphate dehydrogenase deficiency and identification of a novel haplotype 487G>A/IVS5-612(G>C) in the Achang population of Southwestern China
    YinFeng Yang
    Department of Biochemistry, Faculty of Basic Medicine, Kunming University of Medical Sciences, Kunming 650031, China
    Sci China C Life Sci 50:479-85. 2007
    ..Our findings appear to be the first documented report on the G6PD genetics of the AChang people, which will provide important clues to the Achang ethnic group origin and will help prevention and treatment of malaria in this area...
  87. ncbi Correlation of maternal plasma total cell-free DNA and fetal DNA levels with short term outcome of first-trimester vaginal bleeding
    Aihua Yin
    Department of Anatomy, Zhongshan School of Medicine, Sun Yat Sen University, Guangzhou, Guangdong 510089, People s Republic of China
    Hum Reprod 22:1736-43. 2007
    ..The aim of this study was to determine whether maternal plasma fetal DNA and total DNA levels could be used to predict spontaneous abortion...
  88. doi Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma
    Jing Wu
    Department of Biochemistry and Molecular Biology, School of Preclinical and Forensic Medicine, West China Medical Center, Chengdu 610041, Sichuan Province, China
    Genomics 91:443-50. 2008
    ..Furthermore, the hypomethylated and hypermethylated profiles were immediately associated with aberrant imprinting of IGF2 and H19...
  89. ncbi Mediator-free amperometric determination of glucose based on direct electron transfer between glucose oxidase and an oxidized boron-doped diamond electrode
    Jing Wu
    Department of Chemistry, College of Science, Huazhong Agricultural University, Wuhan, 430070, People s Republic of China
    Anal Bioanal Chem 385:1330-5. 2006
    ..67x10(-5) to 2x10(-3) mol/L, with a detection limit of 2.31x10(-5) mol/L. The lifetime, reproducibility and measurement repeatability were evaluated and satisfactory results were obtained...
  90. pmc Effect of vector-expressed shRNAs on hTERT expression
    Ying Guo
    Department of Etiology, Fourth Military Medical University, Xi an 710033, Shaanxi Province, China
    World J Gastroenterol 11:2912-5. 2005
    ..To study the effect of short hairpin RNAs (shRNAs) expressed from DNA vector on hTERT expression...
  91. ncbi Enhancement of bone repair with a helper-dependent adenoviral transfer of bone morphogenetic protein-2
    Nobuhiro Abe
    Department of Orthopaedic Surgery, UCLA School of Medicine, 2 619 MacDonald Research Laboratories, 675 Charles E Young Dr South, Los Angeles, CA 90095, USA
    Biochem Biophys Res Commun 297:523-7. 2002
    ..This type of gene therapy vector could prove to be highly useful for bone augmentation in patients with bone loss associated with trauma, revision total joint arthroplasty, or cancer...