Yun Wang

Summary

Country: China

Publications

  1. pmc Identification of a novel regulatory sequence of actin nucleation promoting factor encoded by Autographa californica multiple nucleopolyhedrovirus
    Yun Wang
    From the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, 430071
    J Biol Chem 290:9533-41. 2015
  2. pmc Inhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo
    Wenbo Zhu
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 7:e45146. 2012
  3. doi The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    Bo Qin
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, China
    Antiviral Res 97:93-100. 2013
  4. doi HBsAg sT123N mutation induces stronger antibody responses to HBsAg and HBcAg and accelerates in vivo HBsAg clearance
    Songxia Li
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    Virus Res 210:119-25. 2015
  5. pmc Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
    Song Xu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, People s Republic of China
    J Virol 86:13025-37. 2012
  6. doi Dioscin's antiviral effect in vitro
    Chaohong Liu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Science, Wuhan 430071, China
    Virus Res 172:9-14. 2013
  7. doi Nuclear receptor 4 group A member 1 determines hepatitis C virus entry efficiency through the regulation of cellular receptor and apolipoprotein E expression
    Wandi Zhu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China University of Chinese Academy of Sciences, Beijing, PR China
    J Gen Virol 95:1510-21. 2014
  8. pmc Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation
    Min Guo
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China University of Chinese Academy of Sciences, Beijing, China
    J Virol 89:2367-77. 2015
  9. doi The protamine-like DNA-binding protein P6.9 epigenetically up-regulates Autographa californica multiple nucleopolyhedrovirus gene transcription in the late infection phase
    Ying Peng
    Key Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Virol Sin 27:57-68. 2012
  10. doi A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy
    Chunchen Wu
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Virol Sin 27:369-72. 2012

Collaborators

Detail Information

Publications24

  1. pmc Identification of a novel regulatory sequence of actin nucleation promoting factor encoded by Autographa californica multiple nucleopolyhedrovirus
    Yun Wang
    From the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, 430071
    J Biol Chem 290:9533-41. 2015
    ....
  2. pmc Inhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo
    Wenbo Zhu
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 7:e45146. 2012
    ..Thus, the HCV core inhibits the induction of a specific immune response to an HBsAg DNA vaccine. However, HCV C also interferes with HBV gene expression and replication in vivo, as observed in patients with coinfection...
  3. doi The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    Bo Qin
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, China
    Antiviral Res 97:93-100. 2013
    ..53 and 12.16, respectively. The testing in in vivo model based on the hydrodynamic injection revealed the antiviral effect of TDF against wild type and mutated HBV genomes and confirmed the reduced the susceptibility of mutant HBV to TDF...
  4. doi HBsAg sT123N mutation induces stronger antibody responses to HBsAg and HBcAg and accelerates in vivo HBsAg clearance
    Songxia Li
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    Virus Res 210:119-25. 2015
    ..Our results help further the understanding of the role of immune escape mutants with N-linked glycosylation in the biology of HBV infection. ..
  5. pmc Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
    Song Xu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, People s Republic of China
    J Virol 86:13025-37. 2012
    ..These data suggest that PLA2G4C plays an important role in the HCV life cycle and might represent a potential target for anti-HCV therapy...
  6. doi Dioscin's antiviral effect in vitro
    Chaohong Liu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Science, Wuhan 430071, China
    Virus Res 172:9-14. 2013
    ..Finally, dioscin's inhibitory effect on secretion of HBeAg and HBsAg in HBV positive cell line HepG2 2.215 was observed by ELISA assay...
  7. doi Nuclear receptor 4 group A member 1 determines hepatitis C virus entry efficiency through the regulation of cellular receptor and apolipoprotein E expression
    Wandi Zhu
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China University of Chinese Academy of Sciences, Beijing, PR China
    J Gen Virol 95:1510-21. 2014
    ..These results explain the delayed spread of HCV in NR4A1 knockdown Huh7.5.1 cells. Thus, NR4A1 plays a role in HCV replication through regulating the expression of HCV receptors and ApoE, and facilitates HCV entry and spread. ..
  8. pmc Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation
    Min Guo
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China University of Chinese Academy of Sciences, Beijing, China
    J Virol 89:2367-77. 2015
    ....
  9. doi The protamine-like DNA-binding protein P6.9 epigenetically up-regulates Autographa californica multiple nucleopolyhedrovirus gene transcription in the late infection phase
    Ying Peng
    Key Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Virol Sin 27:57-68. 2012
    ..9 and host RNA polymerase II in the same transcriptionally active chromatin fraction at 24 hpi, which may probably contribute to viral gene transcription up-regulation in the late infection phase...
  10. doi A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy
    Chunchen Wu
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Virol Sin 27:369-72. 2012
    ....
  11. doi Putative phosphorylation sites on WCA domain of HA2 is essential for Helicoverpa armigera single nucleopolyhedrovirus replication
    Yi Pin Lv
    Key Laboratory of Agricultural and Enviromental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China
    Virol Sin 26:245-51. 2011
    ....
  12. pmc Isolation and characterization of a novel alphanodavirus
    Huimin Bai
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    Virol J 8:311. 2011
    ..The Nodaviridae family consists of two genera: alpha- and beta-nodavirus. Alphanodaviruses usually infect insect cells. Some commercially available insect cell lines have been latently infected by Alphanodaviruses...
  13. doi Adult neural progenitor cells from Huntington's disease mouse brain exhibit increased proliferation and migration due to enhanced calcium and ROS signals
    Wenjuan Xie
    State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China
    Cell Prolif 48:517-31. 2015
    ..In this study, we aimed to elucidate intrinsic properties of ANPCs subjected to neurodegenerative condition in YAC128 HD mice...
  14. pmc Hepatitis C virus induced a novel apoptosis-like death of pancreatic beta cells through a caspase 3-dependent pathway
    Qian Wang
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 7:e38522. 2012
    ..Taken together, our data suggest that HCV infection induces death of pancreatic beta cells through an ER stress-involved, caspase 3-dependent, special pathway...
  15. doi An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs
    Honghe Chen
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
    J Immunol 192:1162-70. 2014
    ..However, NF-κB pathway was still activated by MRP, as MRP retained the ability to interact with inducible inhibitor of NF-κB (iκB) kinase. Thus, MRP acts as a dominant negative regulator of MITA-mediated induction of IFN production. ..
  16. pmc Coexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses
    Liang Cao
    State Key Lab of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China University of Chinese Academy of Sciences, Beijing, China
    J Virol 88:8656-66. 2014
    ....
  17. doi Live imaging of baculovirus infection of midgut epithelium cells: a functional assay of per os infectivity factors
    Jingfang Mu
    Laboratory of Virology, Wageningen University, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, Hubei Province, PR China
    J Gen Virol 95:2531-9. 2014
    ..This is the first live imaging of ODV entry into midgut cells and complements the genetic and biochemical evidence for the role of PIFs in the oral infection process...
  18. pmc The putative pocket protein binding site of Autographa californica nucleopolyhedrovirus BV/ODV-C42 is required for virus-induced nuclear actin polymerization
    Kun Li
    State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, People s Republic of China
    J Virol 84:7857-68. 2010
    ..Furthermore, we have identified the putative pocket protein binding sequence (PPBS) on C42 that is essential for C42 to exert its function in nuclear actin polymerization...
  19. pmc Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg) determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance
    Chunchen Wu
    Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
    J Virol 86:4658-69. 2012
    ..In addition, the presence of proper anti-HBs antibodies is indispensable for the neutralization and clearance of HBsAg during HBV infection...
  20. doi Coordinated regulation of dendrite arborization by epigenetic factors CDYL and EZH2
    Cai Qi
    Neuroscience Research Institute, Department of Neurobiology, School of Basic Medical Sciences, Key Laboratory for Neuroscience, Ministry of Education National Health and Family Planning Commission and Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing 100191, China, Tianjin Key Laboratory of Medical Epigenetics, Tianjin Medical University, Tianjin 300070, China, and PKU IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China
    J Neurosci 34:4494-508. 2014
    ..These results link, for the first time, the epigenetic regulators CDYL and EZH2 to dendrite morphogenesis and might shed new light on our understanding of the regulation of the neurodevelopment. ..
  21. pmc Impaired social decision making in patients with major depressive disorder
    Yun Wang
    Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
    BMC Psychiatry 14:18. 2014
    ....
  22. doi Hyper-coupling between working memory task-evoked activations and amplitude of spontaneous fluctuations in first-episode schizophrenia
    Yuan Zhou
    Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
    Schizophr Res 159:80-9. 2014
    ....
  23. pmc Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease
    Jiu Qiang Wang
    State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
    J Biol Chem 288:3070-84. 2013
    ..Our results also indicate that reducing mitochondrial Ca(2+) uptake could be a therapeutic strategy for HD...
  24. pmc Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks
    Xiuli Zhang
    Laboratory of Cancer Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
    DNA Repair (Amst) 12:377-88. 2013
    ..We speculate that Polκ may have an important role in strand break repair following oxidative stress in vivo...