Yan Wang

Summary

Country: China

Publications

  1. pmc Addition of theophylline or increasing the dose of inhaled corticosteroid in symptomatic asthma: a meta-analysis of randomized controlled trials
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
    Yonsei Med J 52:268-75. 2011
  2. pmc Is Helicobacter pylori infection associated with asthma risk? A meta-analysis based on 770 cases and 785 controls
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Int J Med Sci 9:603-10. 2012
  3. doi request reprint Dendritic cell co-transfected with FasL and allergen genes induces T cell tolerance and decreases airway inflammation in allergen induced murine model
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China
    Mol Biol Rep 38:809-17. 2011
  4. doi request reprint CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses
    Wenlei Zhuo
    Institute of Cancer, Chongqing, China
    Cancer Invest 27:86-95. 2009
  5. doi request reprint Polymorphisms of CYP1A1 and GSTM1 and laryngeal cancer risk: evidence-based meta-analyses
    Wen lei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, 400038 Chongqing, China
    J Cancer Res Clin Oncol 135:1081-90. 2009
  6. doi request reprint Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Lung Cancer 62:8-14. 2008
  7. ncbi request reprint [Effects of house dust mite allergen DNA vaccines on the allergic airway inflammation in murine models]
    Yu tian Bi
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
    Zhonghua Nei Ke Za Zhi 46:930-3. 2007
  8. pmc Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation
    Xue Li Pang
    Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
    World J Gastroenterol 19:1736-48. 2013
  9. pmc CYP1A1 MspI polymorphism and acute myeloid leukemia risk: meta-analyses based on 5018 subjects
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    J Exp Clin Cancer Res 31:62. 2012
  10. doi request reprint ER stress induced by ionising radiation in IEC-6 cells
    Bo Zhang
    Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China
    Int J Radiat Biol 86:429-35. 2010

Collaborators

Detail Information

Publications38

  1. pmc Addition of theophylline or increasing the dose of inhaled corticosteroid in symptomatic asthma: a meta-analysis of randomized controlled trials
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
    Yonsei Med J 52:268-75. 2011
    ..Low-dose theophylline has anti-inflammatory effects. The aim of this study was to evaluate the effects of adding theophylline compared with increasing the dose of inhaled corticosteroid (ICS) on symptomatic asthma...
  2. pmc Is Helicobacter pylori infection associated with asthma risk? A meta-analysis based on 770 cases and 785 controls
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Int J Med Sci 9:603-10. 2012
    ..A number of studies have been devoted to the relationship between H. pylori infection and asthma risk, which have generated inconclusive results. In this study we aimed to derive a more precise estimation of the relationship...
  3. doi request reprint Dendritic cell co-transfected with FasL and allergen genes induces T cell tolerance and decreases airway inflammation in allergen induced murine model
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China
    Mol Biol Rep 38:809-17. 2011
    ..FasL-Der p2-DC was more effective than FasL-DC and Der p2-DC, respectively. These results demonstrate that FasL and allergen genes co-expressing DC might be a promising approach to allergy therapy...
  4. doi request reprint CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses
    Wenlei Zhuo
    Institute of Cancer, Chongqing, China
    Cancer Invest 27:86-95. 2009
    ..The data suggest that variant genotypes of CYP1A1 might not be risk factors for oral cancer, whereas GSTM1 null genotype significantly increases susceptibility to oral cancer in Asians but not Caucasians...
  5. doi request reprint Polymorphisms of CYP1A1 and GSTM1 and laryngeal cancer risk: evidence-based meta-analyses
    Wen lei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, 400038 Chongqing, China
    J Cancer Res Clin Oncol 135:1081-90. 2009
    ..The aim of the present study was to assess the possible associations of laryngeal cancer risk with CYP1A1 genetic variation and GSTM1 null genotype respectively...
  6. doi request reprint Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Lung Cancer 62:8-14. 2008
    ....
  7. ncbi request reprint [Effects of house dust mite allergen DNA vaccines on the allergic airway inflammation in murine models]
    Yu tian Bi
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
    Zhonghua Nei Ke Za Zhi 46:930-3. 2007
    ..To investigate the effects of allergen DNA vaccines on the airway allergic inflammation in C57BL/6 mouse models sensitized and challenged with house dust mite extracts...
  8. pmc Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation
    Xue Li Pang
    Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
    World J Gastroenterol 19:1736-48. 2013
    ..To investigate the role of endoplasmic reticulum (ER) stress in cancer radiotherapy and its molecular mechanism...
  9. pmc CYP1A1 MspI polymorphism and acute myeloid leukemia risk: meta-analyses based on 5018 subjects
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    J Exp Clin Cancer Res 31:62. 2012
    ..However, the results remain conflicting. The aim of the present study was to derive a more precise estimation of the relationship...
  10. doi request reprint ER stress induced by ionising radiation in IEC-6 cells
    Bo Zhang
    Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China
    Int J Radiat Biol 86:429-35. 2010
    ..In our previous study, we found that there might be a causative link between IR and ER stress. In this study, we further characterised the type of ER stress induced by IR...
  11. doi request reprint Enhanced radiosensitivity of EC109 cells by inhibition of HDAC1 expression
    Bo Zhang
    Department of Medical Genetics, College of Basic Medicine, Third Military Medical University, 400038 Chongqing, China
    Med Oncol 29:340-8. 2012
    ..Our data suggested that targeting the increased HDAC1 expression might be feasible for esophageal cancer therapy...
  12. pmc DGKα DNA vaccine relieves airway allergic inflammation in asthma model possibly via induction of T cell anergy
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University Chongqing, 400037, China
    Int J Clin Exp Pathol 6:2404-11. 2013
    ..The results of the present study provide evidence for the potential utility of the administration of DGKα DNA vaccine as an approach to gene therapy for asthma. ..
  13. doi request reprint Adenoviral-mediated up-regulation of Otos, a novel specific cochlear gene, decreases cisplatin-induced apoptosis of cultured spiral ligament fibrocytes via MAPK/mitochondrial pathway
    Xian Lu Zhuo
    Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Toxicology 248:33-8. 2008
    ....
  14. doi request reprint Cyclin D1 G870A polymorphism is a risk factor for esophageal cancer among Asians
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Cancer Invest 30:630-6. 2012
    ..Collectively, results suggest that CCND1 G870A polymorphism might be a low-penetrant risk factor for esophageal carcinoma, particularly among Asians...
  15. doi request reprint Possible association of Helicobacter pylori infection with laryngeal cancer risk: an evidence-based meta-analysis
    Xian Lu Zhuo
    Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Arch Med Res 39:625-8. 2008
    ..pylori infection and laryngeal cancer risk and have yielded conflicting results. In this study, we aimed to evaluate the possible association of H. pylori infection with laryngeal cancer risk...
  16. doi request reprint Suppression of allergic inflammation by allergen-DNA-modified dendritic cells depends on the induction of Foxp3+ Regulatory T cells
    Kui Wu
    Institute of Respiratory Medicine, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Scand J Immunol 67:140-51. 2008
    ..Allergen-modified DC can induce immune tolerance to allergens and reverse the established Th2 responses induced by allergen, with dependence on the induction of Foxp3(+) Tregs...
  17. doi request reprint TP53 codon 72 polymorphism contributes to nasopharyngeal cancer susceptibility: a meta-analysis
    Xian Lu Zhuo
    Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Arch Med Res 40:299-305. 2009
    ..The aim of the present study was to assess possible associations of NPC risk with TP53 codon 72 polymorphisms...
  18. doi request reprint MCM-2 is a therapeutic target of Trichostatin A in colon cancer cells
    Yangbo Liu
    Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Toxicol Lett 221:23-30. 2013
    ..In addition, TSA caused an increase of phosphorylated JNK, which was involved in downregulation of MCM-2. Together, our results suggest that MCM-2 is a noval therapeutic target of TSA in colon cancer cells. ..
  19. pmc CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
    Wenlei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    PLoS ONE 7:e48265. 2012
    ..Published studies on the relationship of CYP2E1 RsaI/PstI polymorphisms with the susceptibility to gastric cancer are controversial. This study aimed to determine this relationship accurately...
  20. doi request reprint Association studies of CYP1A1 and GSTM1 polymorphisms with esophageal cancer risk: evidence-based meta-analyses
    Wen lei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Arch Med Res 40:169-79. 2009
    ..We undertook this study to assess possible associations of esophageal cancer risk with CYP1A1 genetic variation and GSTM1 null genotype, respectively...
  21. pmc Expression and Splice Variant Analysis of Human TCF4 Transcription Factor in Esophageal Cancer
    Gang He
    Department of Medical Genetics, Third Military Medical University, Chongqing 400038, China
    J Cancer 6:333-41. 2015
    ..Here we investigated the splicing isoforms and the roles of TCF4 in human esophageal squamous cell carcinoma...
  22. doi request reprint Helicobacter pylori infection and oesophageal cancer risk: association studies via evidence-based meta-analyses
    Xianlu Zhuo
    Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Clin Oncol (R Coll Radiol) 20:757-62. 2008
    ..Whether infection of H. pylori is a risk factor for this cancer remains uncertain. In this study we aimed to evaluate the association of H. pylori infection with oesophageal cancer risk...
  23. pmc Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway
    Xukai Wang
    Department of Cardiovascular Internal Medicine, Institute of Field Surgery, Daping Hospital, Third Military Medical University, Chongqing, China
    Sci Rep 5:12676. 2015
    ..Our data suggest that inhibition of obesity-induced inflammation alleviates IR, and NaB might be a potential anti-inflammatory agent for obesity. ..
  24. doi request reprint Using PCR-RFLP technology to teach single nucleotide polymorphism for undergraduates
    Bo Zhang
    Department of Medical Genetics, Third Military Medical University, Chongqing, 400038, China
    Biochem Mol Biol Educ 41:262-6. 2013
    ..Students were found to be more enthusiastic during the laboratory classes than those in the former curriculum...
  25. ncbi request reprint Is the application of prostaglandin E1 effective for the treatment of sudden hearing loss? An evidence-based meta-analysis
    Xian Lu Zhuo
    Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing, China Guiyang Medical College, Guiyang, China
    J Int Med Res 36:467-70. 2008
    ..The pooled odds ratio was 1.95 (95% confidence interval: 1.53, 2.50) and the test for overall effect (Z-value) was 5.31 (P < 0.00001), suggesting that PGE(1) is an effective and promising strategy for the treatment of SHL...
  26. doi request reprint Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway
    Wen lei Zhuo
    Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China
    Biochem Biophys Res Commun 369:1098-102. 2008
    ....
  27. pmc Detection of lymphangiogenesis in non-small cell lung cancer and its prognostic value
    Jian guo Sun
    Cancer Institute of People s Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, PR China
    J Exp Clin Cancer Res 28:21. 2009
    ....
  28. doi request reprint NAT2 slow acetylation genotypes contribute to asthma risk among Caucasians: evidence from 946 cases and 1,091 controls
    Yan Wang
    Institute of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, 400038, China
    Mol Biol Rep 41:1849-55. 2014
    ..20; 95% CI 1.31-3.72). The pooled data suggest that slow acetylators of NAT2 might contribute to asthma risk among Caucasians. Future studies are needed to confirm this conclusion...
  29. doi request reprint TALE: a tale of genome editing
    Mingjie Zhang
    Department of Medical Genetics, College of Basic Medical Science, Third Military Medical University, Chongqing 400038, People s Republic of China Battalion 16 of Cadet Brigade, Third Military Medical University, Chongqing 400038, People s Republic of China Electronic address
    Prog Biophys Mol Biol 114:25-32. 2014
    ....
  30. doi request reprint Changes in proteomic features induced by insulin on vascular smooth muscle cells from spontaneous hypertensive rats in vitro
    Yan Wang
    Department of Medical Genetics, Third Military Medical University, Chongqing 400038, China
    Cell Biochem Biophys 58:97-106. 2010
    ..The results showed that insulin plays a crucial role in activating proliferation and migration of VSMCs, by regulating the phenotype switch of VSMCs...
  31. doi request reprint Peroxiredoxins, a novel target in cancer radiotherapy
    Bo Zhang
    Department of Medical Genetics, Third Military Medical University, Chongqing 400038, China
    Cancer Lett 286:154-60. 2009
    ..As Prxs could be induced by radiation and its expression status could determine the radiosensitivity of cancer cells, Prxs might be a potential target for radiotherapy in cancer...
  32. pmc Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells
    Juan Li
    Department of Medical Genetics, College of Basic Medicine, Third Military Medical University, Chongqing, People s Republic of China
    BMC Mol Biol 13:4. 2012
    ..However, the mechanism of miR-34a dysregulation in human malignancies has not been well elucidated. Our study aimed to further investigate the regulation mechanism of miR-34a...
  33. doi request reprint Unique proteomic features induced by a potential antiglioma agent, Nordy (dl-nordihydroguaiaretic acid), in glioma cells
    Xiu Wu Bian
    Institute of Pathology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Proteomics 8:484-94. 2008
    ..Our results suggest that Nordy may constitute a promising drug lead for the development of novel antitumor agents targeting proteins that control tumor cell function at multiple levels...
  34. pmc MiR-10a* up-regulates coxsackievirus B3 biosynthesis by targeting the 3D-coding sequence
    Lei Tong
    Department of Microbiology, Harbin Medical University, 157 Baojian Road, Harbin 150081, China
    Nucleic Acids Res 41:3760-71. 2013
    ..Taken together, these data for the first time show that miRNA* can positively modulate gene expression. MiR-10a* might be involved in the CVB3 cardiac pathogenesis...
  35. ncbi request reprint ERp29 is a radiation-responsive gene in IEC-6 cell
    Bo Zhang
    Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China
    J Radiat Res 49:587-96. 2008
    ..Our results demonstrate that ERp29 is a radiation associated protein and plays an important role in protecting cells from IR...
  36. doi request reprint Comparison of the effects of human β-defensin 3, vancomycin, and clindamycin on Staphylococcus aureus biofilm formation
    Qiang Huang
    Center of Trauma of Daping Hospital, Third Military Medical College, Chongqing, China
    Orthopedics 35:e53-60. 2012
    ..Human β-defensin 3 was significantly more effective against bacteria from the S aureus biofilms than was clindamycin. Vancomycin did not reduce the S aureus biofilm area...
  37. ncbi request reprint Use of unfractionated heparin and a low-molecular-weight heparin following thrombolytic therapy for acute ST-segment elevation myocardial infarction
    Xu Kai Wang
    Daping Hospital, Third Military Medical University, Chongqing, China
    Clin Drug Investig 26:341-9. 2006
    ..This open-label, single-centre, randomised study was conducted to compare the efficacy and safety of parnaparin sodium, a LMWH, with UFH in patients with STEMI...
  38. ncbi request reprint Comparison of inhaled corticosteroid combined with theophylline and double-dose inhaled corticosteroid in moderate to severe asthma
    Yan Wang
    Institute of Respiratory Diseases of PLA, Xinqiao Hospital, The Third Military Medical University, Chongqing, China
    Respirology 10:189-95. 2005
    ..This study was performed to compare the efficacy of inhaled corticosteroids (ICS) combined with slow-release theophylline (SRT) with that of double-dose ICS in asthma control, anti-inflammatory activity and safety...