R T Cheung

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Knowledge of stroke in Hong Kong Chinese
    R T Cheung
    Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong
    Cerebrovasc Dis 9:119-23. 1999
  2. ncbi request reprint Cyclooxygenase-1 gene knockout does not alter middle cerebral artery occlusion in a mouse stroke model
    Raymond T F Cheung
    University Department of Medicine, Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Neurosci Lett 330:57-60. 2002
  3. ncbi request reprint The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 34:153-60. 2003
  4. ncbi request reprint Melatonin protects SHSY5Y neuronal cells but not cultured astrocytes from ischemia due to oxygen and glucose deprivation
    Zhong Pei
    Division of Neurology, University Department of Medicine, Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 34:194-201. 2003
  5. ncbi request reprint Visualization of ischaemic penumbra using a computed tomography perfusion method
    R T F Cheung
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Cerebrovasc Dis 15:182-7. 2003
  6. ncbi request reprint Use of the original, modified, or new intracerebral hemorrhage score to predict mortality and morbidity after intracerebral hemorrhage
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong
    Stroke 34:1717-22. 2003
  7. ncbi request reprint Risk, types, and severity of intracranial hemorrhage in patients with symptomatic carotid artery stenosis
    Raymond T F Cheung
    University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong King, China
    Stroke 34:1847-51. 2003
  8. ncbi request reprint Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam
    J Pineal Res 41:337-43. 2006
  9. ncbi request reprint Update on medical and surgical management of intracerebral hemorrhage
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Rev Recent Clin Trials 2:174-81. 2007
  10. ncbi request reprint Sexual functioning in Chinese stroke patients with mild or no disability
    Raymond T F Cheung
    Division of Neurology, University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, P R China
    Cerebrovasc Dis 14:122-8. 2002

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Knowledge of stroke in Hong Kong Chinese
    R T Cheung
    Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong
    Cerebrovasc Dis 9:119-23. 1999
    ..Most respondents would choose desirable actions if stroke was suspected in their family members or themselves. Friends and relatives, newspapers and magazines, and mass media provided the major sources of their knowledge...
  2. ncbi request reprint Cyclooxygenase-1 gene knockout does not alter middle cerebral artery occlusion in a mouse stroke model
    Raymond T F Cheung
    University Department of Medicine, Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Neurosci Lett 330:57-60. 2002
    ..Our results failed to confirm the harmful effect of losing COX-1 activity due to gene knockout in a permanent endovascular MCAO mouse stroke model...
  3. ncbi request reprint The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 34:153-60. 2003
    ....
  4. ncbi request reprint Melatonin protects SHSY5Y neuronal cells but not cultured astrocytes from ischemia due to oxygen and glucose deprivation
    Zhong Pei
    Division of Neurology, University Department of Medicine, Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 34:194-201. 2003
    ..Our results show that melatonin co-treatment protects cultured neuronal cells but not astrocytes against OGD-induced cell death in a dose-dependent manner and that the neuroprotection is independent of its known membrane receptors...
  5. ncbi request reprint Visualization of ischaemic penumbra using a computed tomography perfusion method
    R T F Cheung
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Cerebrovasc Dis 15:182-7. 2003
    ..CT measurements of CBF, CBV and MTT may visualize the ischaemic penumbra and explain the site of bleeding after surgical decompression...
  6. ncbi request reprint Use of the original, modified, or new intracerebral hemorrhage score to predict mortality and morbidity after intracerebral hemorrhage
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong
    Stroke 34:1717-22. 2003
    ..We studied how well the original ICH Score would predict morbidity and mortality and determined whether modification would improve the predictions...
  7. ncbi request reprint Risk, types, and severity of intracranial hemorrhage in patients with symptomatic carotid artery stenosis
    Raymond T F Cheung
    University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong King, China
    Stroke 34:1847-51. 2003
    ..We sought to report the occurrence and risk factors of intracranial hemorrhage during long-term follow-up of patients with internal carotid artery stenosis, with and without carotid endarterectomy...
  8. ncbi request reprint Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam
    J Pineal Res 41:337-43. 2006
    ..In conclusion, melatonin in propylene glycol markedly elevates plasma levels of melatonin with no serious toxicity. This preparation should be further evaluated in human patients...
  9. ncbi request reprint Update on medical and surgical management of intracerebral hemorrhage
    Raymond Tak Fai Cheung
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Rev Recent Clin Trials 2:174-81. 2007
    ..Microbleeds are commonly seen on magnetic resonance imaging. Further studies are awaited to clarify the association between microbleeds and the future risk of ICH...
  10. ncbi request reprint Sexual functioning in Chinese stroke patients with mild or no disability
    Raymond T F Cheung
    Division of Neurology, University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, P R China
    Cerebrovasc Dis 14:122-8. 2002
    ..Thus, sexual dysfunctions are common in Chinese stroke patients with mild or no disability...
  11. pmc Production and validation of Putonghua- and Cantonese-Chinese language National Institutes of Health Stroke Scale training and certification videos
    R T F Cheung
    Department of Medicine Neurology, and Research Centre of Heart, Brain, Hormone and Healthy Aging, University of Hong Kong, Hong Kong
    Int J Stroke 5:74-9. 2010
    ..We report our experience with new Putonghua- and Cantonese-Chinese language NIHSS (PC-NIHSS and CC-NIHSS) training and certification videos...
  12. ncbi request reprint Circadian variation of stroke onset in Hong Kong Chinese: a hospital-based study
    R T Cheung
    Division of Neurology, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Cerebrovasc Dis 12:1-6. 2001
    ..m. for ICH. There was no difference in the circadian variation between patients with and without prior TIA or stroke. This hospital-based study revealed a significant circadian variation of onset in different types and subtypes of stroke...
  13. ncbi request reprint The insula and cerebrogenic sudden death
    R T Cheung
    Division of Neurology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, People s Republic of China
    Arch Neurol 57:1685-8. 2000
    ....
  14. ncbi request reprint Epileptic seizures attributed to cerebral hyperperfusion after percutaneous transluminal angioplasty and stenting of the internal carotid artery
    D S Ho
    Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, PRC
    Cerebrovasc Dis 10:374-9. 2000
    ....
  15. ncbi request reprint Hong Kong patients' knowledge of stroke does not influence time-to-hospital presentation
    R T Cheung
    Division of Neurology, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    J Clin Neurosci 8:311-4. 2001
    ..056). Thus, improving the general knowledge of stroke among Hong Kong people may not reduce delay in hospital presentation of stroke patients...
  16. doi request reprint Depression literacy among Chinese stroke survivors
    A C K Lee
    Department of Nursing Studies, The University of Hong Kong, Hong Kong SAR, China
    Aging Ment Health 13:349-56. 2009
    ..This paper will report the level of mental health literacy and thematic constructs of depression interpreted by a group of stroke survivors...
  17. ncbi request reprint The smiley as a simple screening tool for depression after stroke: a preliminary study
    A C K Lee
    Department of Nursing Studies, 4 F, William MW Mong Bldg, Academic and Administration Block, Faculty of Medicine, The University of Hong Kong, 21, Sassoon Road, Pokfulam, Hong Kong
    Int J Nurs Stud 45:1081-9. 2008
    ..A simple, non-language-based, culturally neutral, non-verbal and easy to apply tool that is not highly dependent on training will be desirable...
  18. ncbi request reprint Intracarotid abciximab injection to abort impending ischemic stroke during carotid angioplasty
    D S Ho
    Division of Cardiology, Queen Mary Hospital Department of Medicine, The University of Hong Kong, Hong Kong
    Cerebrovasc Dis 11:300-4. 2001
    ..However, the safety and efficacy of abciximab in the treatment of acute ischemic cerebrovascular events is unknown at present...
  19. ncbi request reprint Prevalence of migraine, tension-type headache, and other headaches in Hong Kong
    R T Cheung
    Division of Neurology, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam
    Headache 40:473-9. 2000
    ..CONCLUSIONS: All types of headache were more common in the 1998 study, and the prevalence rates were closer to those of Western communities...
  20. ncbi request reprint Cerebrovascular disease--advances in management
    R T Cheung
    Division of Neurology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Hong Kong Med J 7:58-66. 2001
    ..Neurosurgical treatment is indicated for some patients with ischaemic or haemorrhagic strokes. Prevention of recurrence and rehabilitation are the core components of subsequent management...
  21. ncbi request reprint Cerebral venous thrombosis presenting as unilateral headache and visual blurring in a man with nephrotic syndrome
    K H Chan
    Division of Neurology, University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Hosp Med 65:54-5. 2004
  22. ncbi request reprint The Holmes-Adie plus syndrome
    W Mak
    Division of Neurology, University Department of Medicine, Queen Mary Hospital, Hong Kong
    J Clin Neurosci 7:452. 2000
    ..These findings were suggestive of a dysfunction affecting the brain stem reflex arc. The pathophysiological process of Holmes-Adie syndrome may be more widespread than previously thought...
  23. ncbi request reprint Mechanical thrombectomy in acute proximal middle cerebral artery thrombosis with the alligator retrieval device
    R Lee
    Department of Radiology, Queen Mary Hospital, Hong Kong, China
    Cerebrovasc Dis 23:69-71. 2007
  24. ncbi request reprint Pretreatment with melatonin reduces volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model
    Zhong Pei
    Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam
    J Pineal Res 32:168-72. 2002
    ..These results indicate that pretreatment with melatonin at a dose between 5 and 15 mg/kg protects against focal cerebral ischemia...
  25. ncbi request reprint Hypertensive encephalopathy: BP lowering complicated by posterior circulation ischemic stroke
    W Mak
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, PRC
    Neurology 63:1131-2. 2004
  26. ncbi request reprint Nonthymoma early-onset- and late-onset-generalized myasthenia gravis--a retrospective hospital-based study
    K H Chan
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Clin Neurol Neurosurg 109:686-91. 2007
    ..Differences between nonthymoma early-onset and late-onset MG were reported. We studied the clinical and serological characteristics of nonthymoma AChR Ab-positive-generalized MG patients...
  27. ncbi request reprint Tuberculous meningitis with tuberculomata presenting as postpartum pyrexia of unknown origin
    K H Chan
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Hosp Med 64:306-7. 2003
  28. ncbi request reprint Consensus statement on ischaemic stroke care in Hong Kong
    P W Ng
    Department of Medicine, United Christian Hospital, Kwun Tong, Hong Kong
    Hong Kong Med J 10:124-9. 2004
    ..To issue guidelines for the care of acute stroke in Hong Kong, with the target audience of all health care professionals who are involved in acute stroke care...
  29. ncbi request reprint An epidemiological study of motor neuron disease in Hong Kong
    G C Y Fong
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Amyotroph Lateral Scler Other Motor Neuron Disord 6:164-8. 2005
    ..A territory-wide prospective epidemiological study is indicated...
  30. ncbi request reprint Melatonin reduces nitric oxide level during ischemia but not blood-brain barrier breakdown during reperfusion in a rat middle cerebral artery occlusion stroke model
    Z Pei
    University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 34:110-8. 2003
    ....
  31. ncbi request reprint Cerebral infarcts complicating tuberculous meningitis
    K H Chan
    Division of Neurology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China
    Cerebrovasc Dis 19:391-5. 2005
    ..CI is a common complication of TBM locally, with LAI and multiple CI being common. Two thirds of TBM patients complicated by CI had poor prognosis despite adjunctive dexamethasone treatment...
  32. ncbi request reprint Wilson's disease with depression and parkinsonism
    K H Chan
    Division of Neurology, University Department of Medicine, Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    J Clin Neurosci 12:303-5. 2005
    ..Early diagnosis and initiation of specific treatment are crucial in minimising any further cerebral and hepatic damage as well as securing possible improvement in organ functions...
  33. ncbi request reprint Cerebral venous thrombosis in a gentleman presenting with fever, convulsion and frontotemporal haemorrhages
    K H Chan
    Division of Neurology, University Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong
    J Clin Neurosci 12:186-8. 2005
    ..A high index of suspicion is required when risk factors of CVT are present. CT brain may be normal or showing non-specific findings. Magnetic resonance imaging plus venography, CT venography, or DSA is diagnostic...
  34. ncbi request reprint Intracerebroventricular injection of a neuropeptide Y-Y1 receptor agonist increases while BIBP3226, a Y1 antagonist, reduces the infarct volume following transient middle cerebral artery occlusion in rats
    S H Chen
    Division of Neurology, University Department of Medicine, University of Hong Kong, Pokfulam, Hong Kong
    Neuroscience 116:119-26. 2003
    ..Conversely, inhibiting the Y1 receptors may protect the brain against ischemic injury. Further studies are warranted to confirm the neuroprotective potential of neuropeptide Y-Y1 receptor inhibition...
  35. ncbi request reprint Administration of melatonin after onset of ischemia reduces the volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model
    Zhong Pei
    Division of Neurology, University Department of Medicine, Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong
    Stroke 34:770-5. 2003
    ..The present study was conducted to examine the treatment time window when melatonin was commenced after onset of ischemia...
  36. ncbi request reprint Pretreatment with melatonin exerts anti-inflammatory effects against ischemia/reperfusion injury in a rat middle cerebral artery occlusion stroke model
    Zhong Pei
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    J Pineal Res 37:85-91. 2004
    ..Our results suggest that melatonin treatment mediates neuroprotection against ischemia/reperfusion injury partly via inhibition of the consequential inflammatory response...
  37. ncbi request reprint Melatonin reduces infarction volume in a photothrombotic stroke model in the wild-type but not cyclooxygenase-1-gene knockout mice
    Liang Yu Zou
    Division of Neurology, University Department of Medicine, The University of Hong Kong, Hong Kong
    J Pineal Res 41:150-6. 2006
    ..Melatonin treatment reduces infarct size in the wild-type mice following photothrombotic stroke partly via maintenance of penumbral CBF in which the COX-1-gene may play a role...
  38. ncbi request reprint Neuropeptide Y and its receptor analogs differentially modulate the immunoreactivity for neuronal or endothelial nitric oxide synthase in the rat brain following focal ischemia with reperfusion
    Shao Hua Chen
    Division of Neurology, University Department of Medicine, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    J Biomed Sci 12:267-78. 2005
    ..Specific ir for inducible NOS was undetectable. These opposing effects of NPY-Y1 receptor activation or inhibition on nNOS and eNOS may lead to harmful or beneficial consequences following ischemia/reperfusion...
  39. ncbi request reprint Neuropeptide Y-Y1 receptor agonist worsens while antagonist improves survival of cultured Y1-expressing neuronal cells following oxygen and glucose deprivation
    Shao Hua Chen
    Division of Neurology, University Department of Medicine, University of Hong Kong, Hong Kong
    J Biomed Sci 11:781-8. 2004
    ..The combination of OGD and cultured neuronal cells may be useful in future studies on the neuroprotective and harmful mechanisms of NPY-Y1 receptor inhibition and activation during ischemia, respectively...
  40. ncbi request reprint Idiopathic severe recurrent transverse myelitis: a restricted variant of neuromyelitis optica
    Koon Ho Chan
    Division of Neurology, University Department of Medicine, 4th Floor, Professorial Block, Pokfulam Road, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China
    Clin Neurol Neurosurg 107:132-5. 2005
    ..It is likely to be a distinct idiopathic inflammatory demyelinating disorder restricted to the spinal cord and brainstem different from MS, but within the spectrum of NMO with probably an autoimmune basis...