Wilina Lim

Summary

Affiliation: Tuberculosis and Chest Service
Country: China

Publications

  1. ncbi request reprint Laboratory containment of SARS virus
    Wilina Lim
    Virology Division, Public Health Labortory Services Branch, Centre for Health Protection, Department of Health, Hong Kong
    Ann Acad Med Singapore 35:354-60. 2006
  2. ncbi request reprint A novel coronavirus associated with severe acute respiratory syndrome
    Thomas G Ksiazek
    Special Pathogens Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 348:1953-66. 2003
  3. ncbi request reprint Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
    Thijs Kuiken
    Department of Virology, Erasmus Medical Centre, PO Box 1738, 3000 DR, Rotterdam, Netherlands
    Lancet 362:263-70. 2003
  4. pmc Lack of evidence for human-to-human transmission of avian influenza A (H9N2) viruses in Hong Kong, China 1999
    Timothy M Uyeki
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 8:154-9. 2002
  5. pmc Characterization of a human H5N1 influenza A virus isolated in 2003
    Kyoko Shinya
    Department of Virology, Institute of Medical Science, University of Tokyo, Japan
    J Virol 79:9926-32. 2005
  6. ncbi request reprint First external quality assurance of antibody diagnostic for SARS-new coronavirus
    Matthias Niedrig
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    J Clin Virol 34:22-5. 2005
  7. pmc Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals
    Taronna R Maines
    Influenza Branch, Mail Stop G 16, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Atlanta, GA 30333, USA
    J Virol 79:11788-800. 2005
  8. pmc Automated extraction protocol for quantification of SARS-coronavirus RNA in serum: an evaluation study
    Rossa W K Chiu
    Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    BMC Infect Dis 6:20. 2006
  9. pmc The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome
    Wai Po Chong
    Department of Paediatrics and Adolescent Medicine, The Hong Kong Jockey Club Research Centre, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    BMC Infect Dis 6:82. 2006
  10. ncbi request reprint Three Indonesian clusters of H5N1 virus infection in 2005
    I Nyoman Kandun
    Directorate General of Disease Control and Environmental Health, Ministry of Health, Jakarta, Indonesia
    N Engl J Med 355:2186-94. 2006

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Laboratory containment of SARS virus
    Wilina Lim
    Virology Division, Public Health Labortory Services Branch, Centre for Health Protection, Department of Health, Hong Kong
    Ann Acad Med Singapore 35:354-60. 2006
    ..Audits of these laboratories in 2004 showed that laboratory safety and containment requirements as recommended were generally met...
  2. ncbi request reprint A novel coronavirus associated with severe acute respiratory syndrome
    Thomas G Ksiazek
    Special Pathogens Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 348:1953-66. 2003
    ..We conducted studies to identify the etiologic agent of this outbreak...
  3. ncbi request reprint Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
    Thijs Kuiken
    Department of Virology, Erasmus Medical Centre, PO Box 1738, 3000 DR, Rotterdam, Netherlands
    Lancet 362:263-70. 2003
    ..We did clinical and experimental studies to assess the role of this virus in the cause of SARS...
  4. pmc Lack of evidence for human-to-human transmission of avian influenza A (H9N2) viruses in Hong Kong, China 1999
    Timothy M Uyeki
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 8:154-9. 2002
    ..No serologic evidence of H9N2 infection was found in family members or health-care workers who had close contact with the H9N2-infected children, suggesting that these H9N2 viruses were not easily transmitted from person to person...
  5. pmc Characterization of a human H5N1 influenza A virus isolated in 2003
    Kyoko Shinya
    Department of Virology, Institute of Medical Science, University of Tokyo, Japan
    J Virol 79:9926-32. 2005
    ..This case challenges the view that adaptation to land-based poultry is a prerequisite for the replication of aquatic avian influenza A viruses in humans...
  6. ncbi request reprint First external quality assurance of antibody diagnostic for SARS-new coronavirus
    Matthias Niedrig
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    J Clin Virol 34:22-5. 2005
    ..The overall results clearly demonstrate that serological diagnosis of SARS-CoV remains at an early stage of development, with further technical improvements required, particularly with respect to the use of SARS specific EIAs...
  7. pmc Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals
    Taronna R Maines
    Influenza Branch, Mail Stop G 16, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Atlanta, GA 30333, USA
    J Virol 79:11788-800. 2005
    ..However, the apparent enhancement of virulence of these viruses in humans in 2004 was better reflected in the ferret...
  8. pmc Automated extraction protocol for quantification of SARS-coronavirus RNA in serum: an evaluation study
    Rossa W K Chiu
    Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    BMC Infect Dis 6:20. 2006
    ..In this study, we evaluated the feasibility of automating the serum RNA extraction procedure in order to increase the throughput of the assay...
  9. pmc The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome
    Wai Po Chong
    Department of Paediatrics and Adolescent Medicine, The Hong Kong Jockey Club Research Centre, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    BMC Infect Dis 6:82. 2006
    ..Cytokines play important roles in antiviral action. We examined whether polymorphisms of IFN-gamma,TNF-alpha and IL-10 affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS)...
  10. ncbi request reprint Three Indonesian clusters of H5N1 virus infection in 2005
    I Nyoman Kandun
    Directorate General of Disease Control and Environmental Health, Ministry of Health, Jakarta, Indonesia
    N Engl J Med 355:2186-94. 2006
    ..Since 2003, the widespread ongoing epizootic of avian influenza A (H5N1) among poultry and birds has resulted in human H5N1 cases in 10 countries. The first case of H5N1 virus infection in Indonesia was identified in July 2005...
  11. pmc The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing Chinese
    Man Wai Ng
    Department of Paediatrics and Adolescent Medicine, The Hong Kong Jockey Club Research Centre, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    BMC Infect Dis 7:50. 2007
    ..Chemokines play important roles in inflammation and antiviral action. We examined whether polymorphisms of RANTES, IP-10 and Mig affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS)...
  12. ncbi request reprint Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection
    W K Eddie Ip
    Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, China
    J Infect Dis 191:1697-704. 2005
    ..These results suggest that MBL contributes to the first-line host defense against SARS-CoV and that MBL deficiency is a susceptibility factor for acquisition of SARS...
  13. pmc SARS molecular detection external quality assurance
    Christian Drosten
    Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
    Emerg Infect Dis 10:2200-3. 2004
    ..Of 58 participants, 51 correctly detected virus in all samples > or =9,400 RNA copies per milliliter and none in negative samples. Commercial test kits significantly improved the outcome...
  14. pmc Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China
    Guodong Liang
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China
    Emerg Infect Dis 10:1774-81. 2004
    ..This study shows the effectiveness of a collaborative, multilaboratory response to diagnose SARS...
  15. ncbi request reprint Aetiology: Koch's postulates fulfilled for SARS virus
    Ron A M Fouchier
    Department of Virology, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands
    Nature 423:240. 2003
  16. ncbi request reprint Lung pathology of fatal severe acute respiratory syndrome
    John M Nicholls
    Department of Pathology, University of Hong Kong, Hong Kong Special Administrative Region, China
    Lancet 361:1773-8. 2003
    ..Severe acute respiratory syndrome (SARS) is a novel infectious disease with global impact. A virus from the family Coronaviridae has been identified as the cause, but the pathogenesis is still unclear...
  17. pmc Severe acute respiratory syndrome: Relapse? Hospital infection?
    Owen Tak Yin Tsang
    Emerg Infect Dis 9:1180-1. 2003
  18. ncbi request reprint Virology: SARS virus infection of cats and ferrets
    Byron E E Martina
    Institute of Virology, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands
    Nature 425:915. 2003
  19. pmc Coronavirus-positive nasopharyngeal aspirate as predictor for severe acute respiratory syndrome mortality
    Owen Tak Yin Tsang
    Princess Margaret Hospital, Hong Kong
    Emerg Infect Dis 9:1381-7. 2003
    ..By multivariate analysis, positive RT-PCR on nasopharyngeal aspirate samples was an independent predictor of death within 30 days...
  20. ncbi request reprint Prevalence of subclinical infection by the SARS coronavirus among general practitioners in Hong Kong
    Wai Cho Yu
    Department of Medicine, Princess Margaret Hospital, Hong Kong SAR, China
    Scand J Infect Dis 36:287-90. 2004
    ..The prevalence for seropositivity was thus 0% (95% CI, 0.0%-0.6%). This finding documents the lack of subclinical infection by SARS coronavirus in an at-risk group in the community...
  21. ncbi request reprint Natural course of severe acute respiratory syndrome-associated coronavirus immunoglobulin after infection
    Eugene Y K Tso
    J Infect Dis 190:1706-7; author reply 1707. 2004
  22. pmc SARS-CoV antibody prevalence in all Hong Kong patient contacts
    Gabriel M Leung
    University of Hong Kong, Hong Kong Special Administrative Region, China
    Emerg Infect Dis 10:1653-6. 2004
    ..19%) were positive for SARS coronavirus immunoglobulin G antibody. SARS rarely manifests as a subclinical infection, and at present, wild animal species are the only important natural reservoirs of the virus...
  23. pmc Emergence of new norovirus variants on spring cruise ships and prediction of winter epidemics
    Linda Verhoef
    Center for Infectious Disease Control, Bilthoven, The Netherlands
    Emerg Infect Dis 14:238-43. 2008
    ..Internationally accepted guidelines are needed for reporting, investigating, and controlling norovirus illness on cruise ships in Europe...