Chi Kong Li

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Klebsiella pneumoniae meningitis in thalassemia major patients
    C K Li
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Pediatr Hematol Oncol 18:229-32. 2001
  2. doi request reprint New trend in the epidemiology of thalassaemia
    Chi Kong Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Electronic address
    Best Pract Res Clin Obstet Gynaecol . 2016
  3. pmc Polysaccharides from the root of Angelica sinensis promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway
    Chang Liu
    Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China
    BMC Complement Altern Med 10:79. 2010
  4. ncbi request reprint Interferon and ribavirin as frontline treatment for chronic hepatitis C infection in thalassaemia major
    Chi Kong Li
    Departments of Paediatrics and Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China
    Br J Haematol 117:755-8. 2002
  5. ncbi request reprint Treatment of acute lymphoblastic leukemia in Hong Kong children: HKALL 93 study
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Hematol Oncol 21:1-9. 2003
  6. ncbi request reprint Growth and endocrine function following bone marrow transplantation for thalassemia major
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China
    Pediatr Hematol Oncol 21:411-9. 2004
  7. ncbi request reprint Unrelated umbilical cord blood transplantation in children: experience of the Hong Kong Red Cross Blood Transfusion Service
    C K Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 10:89-95. 2004
  8. ncbi request reprint Improved outcome of acute lymphoblastic leukaemia treated by delayed intensification in Hong Kong children: HKALL97 study
    C K Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 12:33-9. 2006
  9. pmc Liver disease in transfusion dependent thalassaemia major
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Arch Dis Child 86:344-7. 2002
  10. ncbi request reprint Second transplant for a thalassemia patient after graft rejection: with immunosuppression and allogeneic peripheral blood stem cell
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    Pediatr Hematol Oncol 19:267-71. 2002

Collaborators

Detail Information

Publications133 found, 100 shown here

  1. ncbi request reprint Klebsiella pneumoniae meningitis in thalassemia major patients
    C K Li
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Pediatr Hematol Oncol 18:229-32. 2001
    ..They died within a short time despite appropriate antibiotic treatment. Klebsiella meningitis may be more common in transfusion-dependent thalassemia patients...
  2. doi request reprint New trend in the epidemiology of thalassaemia
    Chi Kong Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Electronic address
    Best Pract Res Clin Obstet Gynaecol . 2016
    ..New treatment methods improve the survival of patient with thalassaemia major, but some late complications that occur with longer survival have been recently discovered...
  3. pmc Polysaccharides from the root of Angelica sinensis promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway
    Chang Liu
    Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China
    BMC Complement Altern Med 10:79. 2010
    ....
  4. ncbi request reprint Interferon and ribavirin as frontline treatment for chronic hepatitis C infection in thalassaemia major
    Chi Kong Li
    Departments of Paediatrics and Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China
    Br J Haematol 117:755-8. 2002
    ..2%. Blood consumption was temporarily increased by 30% due to ribavirin-associated haemolysis. This study demonstrated a high, sustained response rate to combination treatment despite infection with genotype 1b...
  5. ncbi request reprint Treatment of acute lymphoblastic leukemia in Hong Kong children: HKALL 93 study
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Hematol Oncol 21:1-9. 2003
    ..Salvage therapy achieved sustained second remission in some patients. More intensive treatment especially a late intensification is required to improve the outcome...
  6. ncbi request reprint Growth and endocrine function following bone marrow transplantation for thalassemia major
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China
    Pediatr Hematol Oncol 21:411-9. 2004
    ..One patient developed diabetes mellitus and one had growth hormone deficiency after BMT. In conclusion, improvement of growth after BMT in TM was common. Gonadal failure is universal in girls, and boys were less affected...
  7. ncbi request reprint Unrelated umbilical cord blood transplantation in children: experience of the Hong Kong Red Cross Blood Transfusion Service
    C K Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 10:89-95. 2004
    ..To review the outcome of unrelated umbilical cord blood transplantation in children using cord blood from the Hong Kong Red Cross Blood Transfusion Service...
  8. ncbi request reprint Improved outcome of acute lymphoblastic leukaemia treated by delayed intensification in Hong Kong children: HKALL97 study
    C K Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 12:33-9. 2006
    ..To study the outcome of children with acute lymphoblastic leukaemia who were treated using a protocol including one or two delayed intensifications...
  9. pmc Liver disease in transfusion dependent thalassaemia major
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Arch Dis Child 86:344-7. 2002
    ..To study the prevalence and severity of liver diseases of transfusion dependent thalassaemia major patients, and correlate the histological and biochemical changes of iron overload in liver with the peripheral blood markers...
  10. ncbi request reprint Second transplant for a thalassemia patient after graft rejection: with immunosuppression and allogeneic peripheral blood stem cell
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    Pediatr Hematol Oncol 19:267-71. 2002
    ..There were no severe treatment-related complications or acute or chronic graft versus host disease after second transplant. The patient remained transfusion independent at 26 months after second transplant...
  11. ncbi request reprint Allogeneic peripheral blood stem cell transplant in children
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Med Pediatr Oncol 30:147-51. 1998
    ..Allogeneic PBSC transplant appears safe in pediatric patients and donors, and it seems not to be associated with increase of acute GVHD or chronic GVHD...
  12. ncbi request reprint Haematopoietic stem cell transplantation for thalassaemia in Chinese patients
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Hong Kong Med J 15:39-41. 2009
    ..The survivors require iron depletion to remove excessive iron store and some may require hormonal replacement therapy. Most of the patients have good quality of life after successful HSCT...
  13. ncbi request reprint A longitudinal study of cardiac function in children with cancer over 40 months
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, China
    Pediatr Hematol Oncol 17:77-83. 2000
    ..Mildly abnormal cardiac indices detected in children after cessation of treatment with anthracycline did not deteriorate in 3 to 4 years follow-up. A longer cardiac follow-up study is indicated to assess the late outcome...
  14. ncbi request reprint Platelet-derived growth factor enhances expansion of umbilical cord blood CD34+ cells in contact with hematopoietic stroma
    Rui Jun Su
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong
    Stem Cells Dev 14:223-30. 2005
    ..Our results provide a rationale for development of a stem cell expansion protocol for clinical applications...
  15. ncbi request reprint Preclinical ex vivo expansion of G-CSF-mobilized peripheral blood stem cells: effects of serum-free media, cytokine combinations and chemotherapy
    Karen Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Eur J Haematol 74:128-35. 2005
    ..This project investigated the effects of culture duration, serum-free media, cytokine combinations, and chemotherapy on the outcomes of expansion...
  16. ncbi request reprint Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis
    Mo Yang
    Li Ka Shing Institute of Health Sciences, Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China
    Stem Cells 25:1800-6. 2007
    ..Serotonin could be developed for clinical ex vivo expansion of hematopoietic stem cells for transplantation. Disclosure of potential conflicts of interest is found at the end of this article...
  17. ncbi request reprint Small peptide analogue of SDF-1alpha supports survival of cord blood CD34+ cells in synergy with other cytokines and enhances their ex vivo expansion and engraftment into nonobese diabetic/severe combined immunodeficient mice
    Karen Li
    Department of Paediatrics, The Chinese University of Hong Kong, 6th Floor, Clinical Sciences Block, Prince of Wales Hospital, Shatin, NT, Hong Kong, People s Republic of China
    Stem Cells 24:55-64. 2006
    ..The small peptide analogue of SDF-1 could be developed for ex vivo expansion and improving engraftment of cord blood transplantation...
  18. ncbi request reprint The plant mannose-binding lectin NTL preserves cord blood haematopoietic stem/progenitor cells in long-term culture and enhances their ex vivo expansion
    Karen Li
    Li Ka Shing Institute of Health Sciences, Department of Paediatrics, The Chinese Uinversity of Hong Kong, Hong Kong, China
    Br J Haematol 140:90-8. 2008
    ....
  19. ncbi request reprint Interleukin-1beta up-regulates the expression of thrombopoietin and transcription factors c-Jun, c-Fos, GATA-1, and NF-E2 in megakaryocytic cells
    Carmen Ka Yee Chuen
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, People s Republic of China
    J Lab Clin Med 143:75-88. 2004
    ..The direct involvement of IL-1beta in the MK lineage may provide an explanation for the phenomenon of thrombocytosis during inflammatory responses...
  20. pmc Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction
    Suk Hang Cheng
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    PLoS ONE 8:e69467. 2013
    ..Moreover, peripheral blood plasma DNA MRD can be an alternative where bone marrow specimen is unavailable and as a less invasive method, which allows close monitoring...
  21. ncbi request reprint Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia
    Hubert Kin Bong Lam
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, P R China
    Int J Oncol 27:537-45. 2005
    ..The multiple-signaling mechanism of ATO warrants it a potential agent to incorporate in the treatment regimen of AMKL...
  22. ncbi request reprint Case report: human herpesvirus 7 associated fatal encephalitis in a peripheral blood stem cell transplant recipient
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 66:493-6. 2002
    ..All microbiological investigations were negative, except for the presence of HHV-7 DNA in cerebrospinal fluid and brain stem tissue samples...
  23. doi request reprint Intact survival of refractory CMV limbic encephalitis in a patient with severe aplastic anemia after unrelated bone marrow transplantation
    Dorothy Yuen Shan Tam
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, New Territories, Hong Kong
    J Pediatr Hematol Oncol 34:472-4. 2012
    ..Donor's CMV-seronegative status may contribute to the delay in controlling this serious infection. Prompt identification of drug-resistant mutant helps in selection of antiviral agents...
  24. doi request reprint Lymphoproliferative response to herpes simplex virus type 1, cytomegalovirus, Epstein-Barr virus, varicella zoster virus, human herpes virus 6, 7, and 8 antigen stimulation in pediatric allogeneic stem cell transplant recipients
    Frankie Wai Tsoi Cheng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Pediatr Transplant 14:761-9. 2010
    ..At 12-month post-transplant, there was no statistical difference in any parameters in affecting LPR to different herpes viruses...
  25. doi request reprint HHV-6 encephalitis in pediatric unrelated umbilical cord transplantation: a role for ganciclovir prophylaxis?
    Frankie Wai Tsoi Cheng
    Department of Pediatrics, Prince of Wales Hospital, and Department of Microbiology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Pediatr Transplant 14:483-7. 2010
    ..Routine use of ganciclovir as HHV-6 prophylaxis in all unrelated HSCT recipients may not be justified but may have a role in unrelated UCB transplant...
  26. doi request reprint The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34+ hematopoietic stem and progenitor cells
    Kam Tong Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong
    Blood 117:1840-50. 2011
    ..CD9 expression on homed CD34(+) cells was significantly up-regulated in vivo. Our results indicate that CD9 might possess specific functions in HSC homing...
  27. ncbi request reprint Trehalose ameliorates the cryopreservation of cord blood in a preclinical system and increases the recovery of CFUs, long-term culture-initiating cells, and nonobese diabetic-SCID repopulating cells
    Xiao Bing Zhang
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Transfusion 43:265-72. 2003
    ..The objective of this study was to establish the cryopreservation of CB under preclinical conditions using trehalose as a supplement to DMSO...
  28. ncbi request reprint The effect of SARS coronavirus on blood system: its clinical findings and the pathophysiologic hypothesis
    Mo Yang
    Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 11:217-21. 2003
    ....
  29. ncbi request reprint Clonal evolution of 8p11 stem cell syndrome in a 14-year-old Chinese boy: a review of literature of t(8;13) associated myeloproliferative diseases
    Wai Shan Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
    Leuk Res 31:235-8. 2007
    ..Also differential clonal TcRgamma gene rearrangements in the BM and LN samples were observed. These findings provide novel insights into the genetic pathogenesis...
  30. pmc Human metapneumovirus detection in patients with severe acute respiratory syndrome
    Paul K S Chan
    Faculty of Medicine of the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Emerg Infect Dis 9:1058-63. 2003
    ..These widely available HEp-2 cells should be included in conjunction with a molecular method for cell culture followup to detect HMPV, particularly in patients with SARS...
  31. doi request reprint Recovery of humoral and cellular immunities to vaccine-preventable infectious diseases in pediatric oncology patients
    Frankie Wai Tsoi Cheng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Pediatr Hematol Oncol 27:195-204. 2010
    ..Near complete immune recovery was demonstrated in the subjects. Significant proportion of subjects remained susceptible to vaccine-preventable infectious diseases up to 18 months after stopping all chemotherapy...
  32. ncbi request reprint Identification of TPO receptors on central nervous system-a preliminary report
    Mo Yang
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 12:494-7. 2004
    ..In conclusion, the first evidence showed the expression of TPO receptor c-mpl in central nervous system. Moreover, the effect of TPO on neural cell proliferation and anti-apoptosis was also demonstrated on in vitro neural cells...
  33. doi request reprint Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia
    Chi Keung Cheng
    Departments of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China
    Blood 118:6638-48. 2011
    ..Taken together, we identified SFRP1 as a transcriptional repression target of the t(8;21) fusion protein and demonstrated a novel mechanism of Wnt activation in a specific subtype of AML...
  34. ncbi request reprint Thrombospondin-1 induces apoptosis in primary leukemia and cell lines mediated by CD36 and Caspase-3
    Karen Li
    Department of Paediatrics, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Int J Mol Med 12:995-1001. 2003
    ..Our data provided strong evidence that TSP-1 exerted direct apoptotic effects on leukemia cells and could be developed as an adjunct to conventional therapy, particularly for leukemia cells that express CD36 or other TSP-1 receptors...
  35. ncbi request reprint Detection of micrometastasis of neuroblastoma to bone marrow and tumor dissemination to hematopoietic autografts using flow cytometry and reverse transcriptase-polymerase chain reaction
    Kam Sze Tsang
    Division of Hematology Blood and Marrow Transplantation, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, China
    Cancer 97:2887-97. 2003
    ..The identification of neuroblastoma metastases to bone marrow (BM) is requisite in staging disease for risk-adopted therapy. However, micrometastases were not elucidated fully...
  36. doi request reprint Fetal stromal niches enhance human embryonic stem cell-derived hematopoietic differentiation and globin switch
    King Yiu Lee
    Department of Pediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong
    Stem Cells Dev 20:31-8. 2011
    ..Our study has provided a strategy for derivation of hematopoietic cells from embryonic stem cells under the influence of primary hematopoietic niches and CM, particularly the FL...
  37. doi request reprint Long-term effects of pamidronate in thalassemic patients with severe bone mineral density deficits
    Ting Fan Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, People s Republic of China
    Hemoglobin 33:361-9. 2009
    ..028, respectively). In contrast, BMD Z-scores at hip worsened in untreated patients (p = 0.034). In conclusion, long-term improvement in BMD in TM patients was observed with bisphosphonate but not calcium and vitamin D treatment...
  38. doi request reprint Prognosis and outcome of relapsed acute lymphoblastic leukemia: a Hong Kong Pediatric Hematology and Oncology Study Group report
    Alex Wing Kwan Leung
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Pediatr Blood Cancer 59:454-60. 2012
    ....
  39. doi request reprint Improved survival outcome of childhood acute myeloid leukemia with intensified chemotherapy in Chinese children
    Xiao Wen Zhai
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Pediatr Hematol Oncol 28:269-78. 2011
    ..01; 43% versus 70%, P = .02, respectively). Intensified chemotherapy improved outcome of Chinese AML children. CR after first course of chemotherapy and WBC at diagnosis were important prognostic factors...
  40. doi request reprint Humoral immune response after post-chemotherapy booster diphtheria-tetanus-pertussis vaccine in pediatric oncology patients
    Frankie Wai Tsoi Cheng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong Hong Kong
    Pediatr Blood Cancer 52:248-53. 2009
    ..In this randomized controlled study, we studied the effect of immune responses to diphtheria-tetanus-pertussis (DTP) booster vaccination in children 6 months after completing chemotherapy...
  41. ncbi request reprint Hematological findings in SARS patients and possible mechanisms (review)
    Mo Yang
    Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong, P R China
    Int J Mol Med 14:311-5. 2004
    ....
  42. ncbi request reprint Clinical presentations and outcome of severe acute respiratory syndrome in children
    K L E Hon
    Department of Paediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, Special Adminstrative Region, China
    Lancet 361:1701-3. 2003
    ..None of the younger children required oxygen supplementation. Compared with adults and teenagers, SARS seems to have a less aggressive clinical course in younger children...
  43. doi request reprint Indiscernible Benefit of Double-Unit Umbilical Cord Blood Transplantation in Children: A Single-Center Experience From Hong Kong
    Kam Sze Tsang
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Cell Transplant 25:1277-86. 2016
    ..Successful prediction of the dominant graft would optimize algorithms of UCB selection and maximize the long-term engraftment of chosen units. ..
  44. pmc Ubiquitous expression of MAKORIN-2 in normal and malignant hematopoietic cells and its growth promoting activity
    King Yiu Lee
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 9:e92706. 2014
    ..Over-expression of MKRN2 in K562 cells increased cell proliferation. Our results indicated possible roles of MKRN2 in normal and malignant hematopoiesis. ..
  45. ncbi request reprint Genetic variation of glycoproteins B and H of human herpesvirus 7 in Hong Kong
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 71:429-33. 2003
    ..4%) Hong Kong isolates were of the gH allele group B, and all others were of the gH allele group C. These data indicate the possibility of using gB or gH alleles as markers for studying world-wide population movements and genetics...
  46. ncbi request reprint Elevated serum interleukin-15 level in acute graft-versus-host disease after hematopoietic cell transplantation
    Ki Wai Chik
    Department of Pediatrics, The Chinese University of Hong Kong, Peoples Republic of China
    J Pediatr Hematol Oncol 25:960-4. 2003
    ..To correlate serum cytokine levels and the development of acute graft-versus-host disease (GVHD), the authors conducted a prospective study on serial measurements of interferon (IFN)-gamma and interleukin (IL)-10, IL-12 and IL-15...
  47. doi request reprint Psychometric properties of the Chinese version of the Pediatric Quality Of Life Inventory 4.0 Generic Core scales among pediatric cancer patients
    Nelson C Y Yeung
    Author Affiliations Department of Psychology, University of Houston, Texas Mr Yeung School of Public Health Dr Lau and Department of Psychology Dr Mak, Chinese University of Hong Kong Centre for Medical Anthropology and Behavioral Health, Sun Yat Sen University, Guangzhou Dr Lau Department of Applied Social Studies, City University of Hong Kong Dr Yu Department of Paediatrics, Prince of Wales Hospital, Hong Kong Dr Chu, Mr Shing, and Drs Leung, LI, and Fok, China
    Cancer Nurs 36:463-73. 2013
    ..Validation of the Generic Core Scales among Chinese pediatric cancer patients has not been reported in the literature. The scales can serve to measure different quality-of-life domains that are not captured by the PedsQL Cancer Module...
  48. pmc A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia
    Chi Keung Cheng
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Haematologica 98:913-7. 2013
    ..Together, our findings uncover a microRNA-mediated control of NPM1 expression that contributes to disease heterogeneity and suggest additional prognostic values of NPM1 in acute myeloid leukemia...
  49. ncbi request reprint Neurocutaneous melanomatosis with a rapidly deteriorating course
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, Hong Kong, China
    AJNR Am J Neuroradiol 24:287-90. 2003
    ..We present serial MR imaging findings in the brain and spine of a child with congenital giant hairy nevi who developed progressive leptomeningeal melanomatosis and whose neurologic condition rapidly deteriorated...
  50. doi request reprint Humoral response to conjugate pneumococcal vaccine in paediatric oncology patients
    Frankie Wai Tsoi Cheng
    Department of Paediatrics, 6 F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong
    Arch Dis Child 97:358-60. 2012
    ..Pneumococcal conjugate vaccine (PCV) is an effective way to prevent invasive pneumococcal diseases in high risk populations. The efficacy of this vaccine in paediatric oncology patients remains unknown...
  51. ncbi request reprint Thrombospondin-1 inhibits in vitro megakaryocytopoiesis via CD36
    Mo Yang
    Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Thromb Res 109:47-54. 2003
    ..Thus, our findings represent the first demonstration that TSP-1 inhibits in vitro megakaryocytopoiesis via interaction with CD36...
  52. ncbi request reprint Autoimmune hypothyroidism after unrelated haematopoietic stem cell transplantation in children
    Vincent Lee
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    J Pediatr Hematol Oncol 28:293-5. 2006
    ..The causes of post-transplantation autoimmune hypothyroidism are probably multiple. In these two patients, the presence of chronic graft-versus-host disease may be the most significant contributing factor...
  53. ncbi request reprint Bone marrow transplantation for beta-thalassaemia major by an HLA-mismatched parent
    C F Li
    Department of Pediatrics, Nanfang Hospital, Guangzhou, China
    J Paediatr Child Health 38:308-10. 2002
    ..A more intensive immunosuppressive regimen and a higher marrow cell dose may be important for successful engraftment. High-dose anti-thymocyte globulin may also prevent severe GVHD...
  54. doi request reprint Acute Leukemia in Down Syndrome Children in Hong Kong: Retrospective Review
    Grace Kee See Lam
    Department of Pediatrics, Prince of Wales Hospital, the Chinese University of Hong Kong Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, the University of Hong Kong Department of Pediatrics, Queen Elizabeth Hospital Department of Pediatrics and Adolescent Medicine, Tuen Mun Hospital Department of Pediatrics and Adolescent Medicine, Princess Margaret Hospital, Hong Kong
    J Pediatr Hematol Oncol 38:102-6. 2016
    ..Children with Down syndrome (DS) are at higher risk of developing acute leukemia. Treatment continues to evolve as we accumulate better understanding of the distinctive clinical and biological features of acute leukemia in DS patients...
  55. doi request reprint Central nervous system tumors in chinese children under the age of 3: a population study
    Anthony Pak Yin Liu
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong Department of Paediatrics, Queen Elizabeth Hospital Department of Paediatics and Adolescent Medicine, Tuen Mun Hospital Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Hong Kong Special Administrative Region, China
    J Pediatr Hematol Oncol 37:94-103. 2015
    ..Disease outcome appeared to be better in our cohort comparing to previous reports probably due to the higher proportion of GCT locally. ..
  56. doi request reprint A 20-year prospective study of Wilms tumor and other kidney tumors: a report from Hong Kong pediatric hematology and oncology study group
    Ching Ching Chan
    Department of Pediatrics, Lady Pao Children s Cancer Centre Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT Department of Pediatrics, Queen Elizabeth Hospital Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital Department of Pediatrics and Adolescent Medicine, Princess Margaret Hospital Department of Pediatrics, Tuen Mun Hospita, Hong Kong
    J Pediatr Hematol Oncol 36:445-50. 2014
    ..Renal tumors are one of the most common tumors in children. We aim at evaluating the characteristics and the outcome of Wilms tumor and other malignant kidney tumors in Hong Kong...
  57. ncbi request reprint Second malignant neoplasms in childhood cancer survivors in a tertiary paediatric oncology centre in Hong Kong, China
    Wai Fun Sun
    Department of Paediatrics and Adolescent Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China
    Chin Med J (Engl) 124:3686-92. 2011
    ..The aim of this study is to evaluate the incidence, risk factors and outcome of second malignant neoplasms in childhood cancer survivors in a tertiary paediatric oncology centre in Hong Kong, China...
  58. doi request reprint Oral arsenic trioxide for relapsed acute promyelocytic leukemia in pediatric patients
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Pediatr Blood Cancer 58:630-2. 2012
    ..Oral As(2) O(3) , particularly in prolonged maintenance with oral ATRA may obviate the need of stem cell transplantation in relapsed pediatric APL...
  59. doi request reprint Post-transplant EBV-related lymphoproliferative disorder complicating umbilical cord blood transplantation in patients of adrenoleukodystrophy
    Frankie Wai Tsoi Cheng
    Department of Pediatrics, Lady Pao Children s Cancer Centre, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Pediatr Blood Cancer 53:1329-31. 2009
    ....
  60. doi request reprint Pulmonary metastases in children with osteosarcoma: characteristics and impact on patient survival
    Darshana D Rasalkar
    Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing St, Shatin, New Territories, Hong Kong
    Pediatr Radiol 41:227-36. 2011
    ..Previous studies have shown that the overall survival rate among patients with localized osteosarcoma without metastatic disease is approximately 60-70% whereas survival rate reduces to 10-30% in patients with metastatic disease...
  61. ncbi request reprint Platelet-derived growth factor up-regulates the expression of transcription factors NF-E2, GATA-1 and c-Fos in megakaryocytic cell lines
    Cecilia Mei Yan Chui
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, 6th Floor, Clinical Sciences Building, Shatin, N T, Hong Kong, People s Republic of China
    Cytokine 21:51-64. 2003
    ..Our data suggest a direct stimulatory effect of PDGF on c-Fos, GATA-1 and NF-E2 expressions and we speculate that these transcription factors might be involved in the signal transduction of PDGF on the regulation of megakaryocytopoiesis...
  62. ncbi request reprint Haematopoietic stem cell transplantation for thalassaemia major in Hong Kong: prognostic factors and outcome
    C K Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Bone Marrow Transplant 29:101-5. 2002
    ..Patients aged more than 11 years were more inclined to develop VOD. In conclusion, haematopoietic stem cell transplantation should be performed early if an HLA identical sibling is available...
  63. ncbi request reprint Eye of the storm: the roles of a radiology department in the outbreak of severe acute respiratory syndrome
    S S Y Ho
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong, China
    AJR Am J Roentgenol 181:19-24. 2003
  64. ncbi request reprint Immunogenicity of a two-dose regime of varicella vaccine in children with cancers
    Ting Fan Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Eur J Haematol 72:353-7. 2004
    ..Live-attenuated varicella vaccine is effective and safe in immunocompetent children. In this study, we assess the immunogenicity and adverse events following varicella vaccination in immunosuppressed cancer children...
  65. ncbi request reprint Patterns of bone diseases in transfusion-dependent homozygous thalassaemia major: predominance of osteoporosis and desferrioxamine-induced bone dysplasia
    Yu Leung Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Pediatr Radiol 32:492-7. 2002
    ..To study the radiographic skeletal changes in transfusion-dependent homozygous beta-thalassaemia...
  66. ncbi request reprint Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin
    Karen Li
    Department of Pediatrics, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Circulation 113:2211-20. 2006
    ..Our hypothesis is that the hematopoietic/megakaryocytopoietic growth factor thrombopoietin (TPO) protects against DOX-induced cardiotoxicity and might involve antiapoptotic mechanism exerted on cardiomyocytes...
  67. ncbi request reprint Periorbital alveolar soft part sarcoma with radiologic features mimicking haemangioma
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Med Pediatr Oncol 41:145-6. 2003
  68. doi request reprint Nonhematopoietically derived DNA is shorter than hematopoietically derived DNA in plasma: a transplantation model
    Yama W L Zheng
    Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Clin Chem 58:549-58. 2012
    ..The size difference between maternal- and fetal-derived DNA in maternal plasma prompted us to investigate whether there was any discrepancy in molecular size between hematopoietically and nonhematopoietically derived DNA in plasma...
  69. ncbi request reprint Liver volume in thalassaemia major: relationship with body weight, serum ferritin, and liver function
    Yu Leung Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Pediatr Radiol 35:165-8. 2005
    ..It is not known whether body weight alone can adjust for the volume of liver in the calculation of the chelating dose in beta-thalassaemia major patients, who frequently have iron overload and hepatitis...
  70. doi request reprint Validation of the Chinese version of the Pediatric Quality of Life Inventory (PedsQL) Cancer Module
    Joseph T F Lau
    Centre for Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
    J Pediatr Psychol 35:99-109. 2010
    ..The psychometric properties of the Chinese version of the Pediatric Quality of Life Inventory (PedsQL) Cancer Module were investigated...
  71. ncbi request reprint Cobblestone area-forming cells, long-term culture-initiating cells and NOD/SCID repopulating cells in human neonatal blood: a comparison with umbilical cord blood
    X B Zhang
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong
    Bone Marrow Transplant 30:557-64. 2002
    ..Our study confirms that NB contains pluripotent hematopoietic stem and progenitor cells capable of homing and engrafting the NOD/SCID mice...
  72. ncbi request reprint Outcomes and prognostic factors of Chinese children with acute lymphoblastic leukemia in Hong Kong: preliminary results
    M M Shing
    Lady Pao Children s Cancer Centre, Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT
    Med Pediatr Oncol 32:117-23. 1999
    ..The Chinese population is the biggest ethnic group in the world. However, there are few reports on the treatment outcome of childhood acute lymphoblastic leukaemia (ALL) among the Chinese population...
  73. ncbi request reprint Preclinical ex vivo expansion of cord blood hematopoietic stem and progenitor cells: duration of culture; the media, serum supplements, and growth factors used; and engraftment in NOD/SCID mice
    A C Lam
    Department of Paediatrics, Laboratory Animal Services Centre, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Transfusion 41:1567-76. 2001
    ..CONCLUSION: The data supported the strategy of expansion. The optimized condition may be applicable to clinical expansion for the abrogation or reduction of posttransplant cytopenia...
  74. ncbi request reprint Human herpesvirus-6 encephalitis after unrelated umbilical cord blood transplant in children
    K W Chik
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, People s Republic of China
    Bone Marrow Transplant 29:991-4. 2002
    ..In conclusion, HHV-6 encephalitis is not uncommon among patients undergoing umbilical cord blood transplantation. It is worth conducting further studies on early diagnosis and optimal management of this potentially fatal disease...
  75. ncbi request reprint White matter and cerebral metabolite changes in children undergoing treatment for acute lymphoblastic leukemia: longitudinal study with MR imaging and 1H MR spectroscopy
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, Medical Physics Div, Chinese Univ of Hong Kong, Prince of Wales Hosp, 30 32 Ngan Shing St, Shatin, Hong Kong SAR, China
    Radiology 229:659-69. 2003
    ..To assess the development of white matter and cerebral metabolite changes during and after treatment in children with acute lymphoblastic leukemia...
  76. pmc Laboratory diagnosis of SARS
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Emerg Infect Dis 10:825-31. 2004
    ..Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity...
  77. ncbi request reprint Thrombocytopenia in patients with severe acute respiratory syndrome (review)
    Mo Yang
    Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Hematology 10:101-5. 2005
    ....
  78. ncbi request reprint Translocation (11;13)(q23;q14) as the sole abnormality in a childhood de novo acute myelocytic leukemia
    Kam Sze Tsang
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Hong Kong, China
    Cancer Genet Cytogenet 150:78-80. 2004
    ..This report of childhood de novo AML harboring t(11;13)(q23;q14) as the sole cytogenetic abnormality provides more data on the leukemogenesis of de novo AML with a 11q23 rearrangement...
  79. ncbi request reprint Ribavirin for SARS in children
    Wai Tsoi Frankie Cheng
    Department of Pediatrics, 6 F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong
    Clin Pediatr (Phila) 43:193-6. 2004
  80. doi request reprint Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis
    Emily C W Hung
    Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Clin Chem 55:715-22. 2009
    ..Although DNA in the urine has the potential to provide a completely noninvasive source of nucleic acids for molecular diagnosis, its existence remains controversial...
  81. ncbi request reprint Scope and limitations of limb-sparing surgery in childhood sarcomas
    Shekhar Madukar Kumta
    Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    J Pediatr Orthop 22:244-8. 2002
    ..The decision of whether to proceed with limb salvage surgery must depend on the aggressiveness of the underlying tumor, its stage, the feasibility of obtaining tumor-free resection margins, and the response to neoadjuvant therapy...
  82. ncbi request reprint HLA-B67 may be a male-specific HLA marker of susceptibility to relapsed childhood ALL in Hong Kong Chinese and HLA-A33 or HLA-B17 signifies a higher presentation leukocytosis: A retrospective analysis on 53 transplant candidates (1989-2003)
    Margaret H L Ng
    Hematology Section, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, People s Republic of China
    Ann Hematol 85:535-41. 2006
    ..006) or HLA-B17 (p < 0.001) signifies higher leukocytosis at presentation. Taken together, our findings support the involvement of HLA in Chinese high-risk childhood ALL...
  83. ncbi request reprint Bone mineral density in children with thalassaemia major: determining factors and effects of bone marrow transplantation
    T F Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Bone Marrow Transplant 36:331-6. 2005
    ..d.) osteocalcin levels in BMT and BT groups were 96.4 (72.7) microg and 68.9 (40.3) microg/l, respectively (P=0.037). In conclusion, severe BMD deficit is common in Chinese TM patients and BMT may reverse BMD deficit in these patients...
  84. pmc Infection control for SARS in a tertiary neonatal centre
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, China
    Arch Dis Child Fetal Neonatal Ed 88:F405-9. 2003
    ..We hope this information is useful in helping other units to formulate their own infection control plans according to their own unit configuration and clinical needs...
  85. ncbi request reprint Imaging findings of paediatric oncology patients presenting with acute neurological symptoms
    W C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Clin Radiol 58:589-603. 2003
    ..If the CT is negative, magnetic resonance imaging (MRI) should be performed, which is more sensitive for detection of CNS lesions...
  86. ncbi request reprint Severe acute respiratory syndrome: avoiding the spread of infection in a radiology department
    A D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S A R China
    AJR Am J Roentgenol 181:25-7. 2003
  87. ncbi request reprint Severe chronic neutropenia in Chinese children in Hong Kong
    T F Leung
    Department of Paediatrics, Prince of Wales Hospital, Hong Kong SAR, China
    J Paediatr Child Health 37:137-41. 2001
    ..Severe chronic neutropenia (SCN) is a rare and heterogeneous disorder in children. The epidemiology, clinical features and outcomes of SCN in Chinese children were reviewed...
  88. ncbi request reprint Long-term cerebral metabolite changes on proton magnetic resonance spectroscopy in patients cured of acute lymphoblastic leukemia with previous intrathecal methotrexate and cranial irradiation prophylaxis
    Y L Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Int J Radiat Oncol Biol Phys 50:759-63. 2001
    ....
  89. ncbi request reprint Clearance of TT virus after allogeneic bone marrow transplantation
    P K Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, SAR
    J Pediatr Hematol Oncol 23:57-8. 2001
    ..Thus, the conditioning regimen may have depleted the hemic cells and the hematologically compartmentalized TTV. The potential of hemic tropism of TTV and its role in hematologic diseases need to be considered...
  90. pmc Anti B cell targeted immunotherapy for treatment of refractory autoimmune haemolytic anaemia in a young infant
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong
    Arch Dis Child 88:337-9. 2003
    ..Paediatricians should be aware of this useful therapeutic tool for treatment of refractory autoimmune haemolytic anaemia and balance its use against the risk of potential life threatening infection...
  91. ncbi request reprint Haematopoietic stem and progenitor cells in human term and preterm neonatal blood
    K Li
    Department of Paediatrics, The Chinese University of Hong Kong, 6th Floor, The Prince of Wales Hospital, Shatin, N T Hong Kong, China
    Vox Sang 80:162-9. 2001
    ..To further investigate the mechanism of the change of stem and progenitor cells in NB, we measured the steady-state levels of CD34+ cells, early progenitor subsets and the expression of adhesion molecules, in term and preterm neonates...
  92. ncbi request reprint Prevalence and genotype distribution of TT virus in various specimen types from thalassaemic patients
    P K Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Viral Hepat 8:304-9. 2001
    ..TTV-infected patients often harbour multiple genotypes suggesting infection with one genotype does not necessarily confer protection against the others. No correlation between TTV infection and liver dysfunction was observed...
  93. ncbi request reprint Liver iron estimation in beta-thalassaemia: comparison of MRI biochemical assay and histological grading
    Y L Chan
    Department of Diagnostic Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shaitin, NT, Hong Kong
    Clin Radiol 56:911-6. 2001
    ....
  94. pmc Respiratory function in patients with thalassaemia major: relation with iron overload
    A M Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, China
    Arch Dis Child 87:328-30. 2002
    ..1) To determine the pattern of respiratory impairment in children with thalassaemia major (TM); (2) to assess the relation between the degree of respiratory impairment and total body iron content...
  95. ncbi request reprint Transfusion of peripheral blood stem cells from donor homozygous for a shared HLA-haplotype: avoiding fatal transfusion-associated graft-versus-host disease while preserving anti-leukemic effect
    R Wong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital
    Transplantation 71:487-90. 2001
    ..CONCLUSIONS: Peripheral blood stem cells transplantation from a donor with a homozygous shared haplotype is possible with a minimal preparative regimen...
  96. ncbi request reprint Severe acute respiratory syndrome: 'SARS' or 'not SARS'
    A M Li
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    J Paediatr Child Health 40:63-5. 2004
    ..We report five cases to illustrate the difficulties and dilemmas faced by clinicians in diagnosing SARS in children...
  97. ncbi request reprint Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: prospective observational study
    K W Chik
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 10:103-6. 2004
    ..To determine the role of oseltamivir prophylaxis for immunocompromised patients...
  98. ncbi request reprint Infection control for SARS in a tertiary paediatric centre in Hong Kong
    T F Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    J Hosp Infect 56:215-22. 2004
    ..In conclusion, stringent infection control precautions, appropriate triage and prompt isolation of potential SARS patients may have contributed to a lack of nosocomial spread and HCW acquisition of SARS in our unit...
  99. ncbi request reprint Risk factors and clinical consequences of human herpesvirus 7 infection in paediatric haematopoietic stem cell transplant recipients
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 72:668-74. 2004
    ..The administration of colony stimulating factor, occurrence of acute graft versus host disease, time to neutrophil and platelet engraftment showed no significant association with the occurrence of HHV-7 DNAaemia...
  100. ncbi request reprint Multipotent neural precursors express neural and hematopoietic factors, and enhance ex vivo expansion of cord blood CD34+ cells, colony forming units and NOD/SCID-repopulating cells in contact and noncontact cultures
    K Li
    Department of Paediatrics, The Chinese University of Hong Kong, 6th Floor Clinical Sciences Block, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Leukemia 19:91-7. 2005
    ..Our data provided the first evidence on the promoting effects of a neural progenitor cell line on hematopoiesis at a noncontact condition. The mechanism could be mediated by the expression of multilineage regulatory factors...
  101. ncbi request reprint Flow cytometric assessment of oxidant stress in age-fractionated thalassaemic trait erythrocytes and its relationship to in vitro growth of Plasmodium falciparum
    A C Senok
    Department of Paediatrics, Chinese University of Hong Kong, Shatin NT, Hong Kong
    Parasitology 116:1-6. 1998
    ..Our findings indicate an association between red cell age, oxidant stress and P. falciparum growth, providing further support for the role of oxidant stress in mediating the protective effect against malaria in thalassaemic RBC...