Chunsheng Dong

Summary

Affiliation: Suzhou University
Country: China

Publications

  1. doi request reprint Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
    Chunsheng Dong
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou 215123, China Electronic address
    Antiviral Res 118:110-7. 2015
  2. pmc RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation
    Chunsheng Dong
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou 215123, PR China
    Gene 519:279-87. 2013
  3. doi request reprint AIM2 co-immunization favors specific multifunctional CD8(+) T cell induction and ameliorates coxsackievirus B3-induced chronic myocarditis
    Dafei Chai
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Antiviral Res 119:68-77. 2015
  4. doi request reprint M cell-targeting strategy facilitates mucosal immune response and enhances protection against CVB3-induced viral myocarditis elicited by chitosan-DNA vaccine
    Ting Ye
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, 199 Ren Ai Road, Suzhou 215123, Jiangsu, PR China
    Vaccine 32:4457-65. 2014
  5. pmc Mucosal immunization with high-mobility group box 1 in chitosan enhances DNA vaccine-induced protection against coxsackievirus B3-induced myocarditis
    Maowei Wang
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, People s Republic of China
    Clin Vaccine Immunol 20:1743-51. 2013
  6. ncbi request reprint Coxsackievirus B3 infection induces autophagic flux, and autophagosomes are critical for efficient viral replication
    Xiaodan Shi
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, 215123, People s Republic of China
    Arch Virol . 2016
  7. doi request reprint In vivo delivery of interleukin-35 relieves coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells
    Yadong Hu
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, 215123, China
    Arch Virol 159:2411-9. 2014
  8. ncbi request reprint Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production
    Baihui Li
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, China
    Clin Exp Rheumatol 32:705-14. 2014
  9. doi request reprint Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus
    Pengli Xiao
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Gene 547:300-9. 2014
  10. doi request reprint A vesicular stomatitis virus-based mucosal vaccine promotes dendritic cell maturation and elicits preferable immune response against coxsackievirus B3 induced viral myocarditis
    Fei Wu
    Soochow University, Jiangsu Key Laboratory of Infection and Immunity Institutes of Biology and Medical Science, Suzhou 215123, China
    Vaccine 32:3917-26. 2014

Collaborators

  • Sidong Xiong
  • Wei Xu
  • Mei Zhong
  • Li Wu
  • Yan Yue
  • Fei Wu
  • Xiaodan Shi
  • Dafei Chai
  • Tengfei Song
  • Baihui Li
  • Ting Ye
  • Yadong Hu
  • Pengli Xiao
  • Jin He
  • Maowei Wang
  • Shengjie Tang
  • Zijian Chen
  • Xingjuan Fan
  • Xiangmei Fan
  • Yongbing Shi
  • Xiaoyun Li

Detail Information

Publications12

  1. doi request reprint Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
    Chunsheng Dong
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou 215123, China Electronic address
    Antiviral Res 118:110-7. 2015
    ..In conclusion, the designed CRISPR/Cas9 system can accurately and efficiently target HBV cccDNA and inhibit HBV replication. This system may be used as a novel therapeutic strategy against chronic HBV infection. ..
  2. pmc RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation
    Chunsheng Dong
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou 215123, PR China
    Gene 519:279-87. 2013
    ..These molecules and pathways may represent candidate targets involved in the pathophysiology of these important immune cells...
  3. doi request reprint AIM2 co-immunization favors specific multifunctional CD8(+) T cell induction and ameliorates coxsackievirus B3-induced chronic myocarditis
    Dafei Chai
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Antiviral Res 119:68-77. 2015
    ..This study may represent a novel therapy for CVB3-induced chronic myocarditis. ..
  4. doi request reprint M cell-targeting strategy facilitates mucosal immune response and enhances protection against CVB3-induced viral myocarditis elicited by chitosan-DNA vaccine
    Ting Ye
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, 199 Ren Ai Road, Suzhou 215123, Jiangsu, PR China
    Vaccine 32:4457-65. 2014
    ....
  5. pmc Mucosal immunization with high-mobility group box 1 in chitosan enhances DNA vaccine-induced protection against coxsackievirus B3-induced myocarditis
    Maowei Wang
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, People s Republic of China
    Clin Vaccine Immunol 20:1743-51. 2013
    ..This strategy may represent a promising approach to candidate vaccines against CVB3-induced myocarditis. ..
  6. ncbi request reprint Coxsackievirus B3 infection induces autophagic flux, and autophagosomes are critical for efficient viral replication
    Xiaodan Shi
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, 215123, People s Republic of China
    Arch Virol . 2016
    ..However, inhibitors of lysosomal acidification, fusion, or degradation did not affect viral replication. Therefore, autolysosomes may not be critical for viral replication in vitro...
  7. doi request reprint In vivo delivery of interleukin-35 relieves coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells
    Yadong Hu
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, 215123, China
    Arch Virol 159:2411-9. 2014
    ..This suggests that supplementation with IL-35 could be a novel therapeutic treatment for viral myocarditis. ..
  8. ncbi request reprint Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production
    Baihui Li
    Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, China
    Clin Exp Rheumatol 32:705-14. 2014
    ..It has been reported that autophagy has a crosstalk with autoimmunity, but its impact on the pathogenesis of SLE remains unclear. Here, we investigated the role of autophagy in inflammatory response of macrophages under SLE conditions...
  9. doi request reprint Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus
    Pengli Xiao
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Gene 547:300-9. 2014
    ..The data not only provide a better understanding of miRNA-mediated macrophage polarization but also demonstrate the future therapeutic potential of targeting miRNAs in SLE patients...
  10. doi request reprint A vesicular stomatitis virus-based mucosal vaccine promotes dendritic cell maturation and elicits preferable immune response against coxsackievirus B3 induced viral myocarditis
    Fei Wu
    Soochow University, Jiangsu Key Laboratory of Infection and Immunity Institutes of Biology and Medical Science, Suzhou 215123, China
    Vaccine 32:3917-26. 2014
    ..These findings support VSV as a viral delivery vector that can induce robust mucosal immunity that should be considered for further vaccine development. ..
  11. doi request reprint Signaling lymphocyte-activation molecule SLAMF1 augments mycobacteria BCG-induced inflammatory response and facilitates bacterial clearance
    Tengfei Song
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Int J Med Microbiol 305:572-80. 2015
    ..7 cells and mice. ..
  12. ncbi request reprint MiR-21 confers resistance against CVB3-induced myocarditis by inhibiting PDCD4-mediated apoptosis
    Jin He
    Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, PR China
    Clin Invest Med 36:E103-11. 2013
    ..In this study, the key myocardial miRNA, miR-21, was identified in the murine coxsackievirus B3 (CVB3)-induced myocarditis model and its contribution to disease progression was explored...