Hui Huang

Summary

Affiliation: Sun Yat-sen University
Country: China

Publications

  1. ncbi request reprint [Establishment of transgenic mouse model of familial amyotrophic lateral sclerosis and identification of the filial generation]
    Hui Huang
    Neurology Department, First Affiliated Hospital, Sun Yat Sen University, 510080, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:258-60, 265. 2006
  2. ncbi request reprint [Effect of transplantation of wild-type bone marrow stem cells in mouse model of familial amyotrophic lateral sclerosis]
    Hui Huang
    Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:562-6. 2006
  3. ncbi request reprint [Brain-derived neurotrophic factor induces rat bone marrow stromal cells to differentiate into neuron-like cells in vitro]
    Wen Huang
    Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
    Di Yi Jun Yi Da Xue Xue Bao 24:854-8. 2004
  4. ncbi request reprint [In vitro differentiation of rat bone mesenchymal stem cells into neuron-like cells induced by vitamin A acid etc]
    Yun an Tang
    Department of Toxicology, West China School of Public Health, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 34:377-80. 2003
  5. ncbi request reprint A new dynamic model of CD8+ T effector cell responses via CD4+ T helper-antigen-presenting cells
    Jim Xiang
    Research Unit, Saskatchewan Cancer Agency, Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Immunol 174:7497-505. 2005
  6. ncbi request reprint [The study of committed differentiation from adult rMSCs into neuron-like cells induced by Xiangdan injection in vitro]
    Hui Huang
    Neurology Department of the First Affiliated Hospital of Sun Yat sen University, Guangzhou
    Zhong Yao Cai 27:585-9. 2004
  7. ncbi request reprint [Characteristics of oriented induction of xiangdan injection on differentiation of marrow mesenchymal stem cells into neurons and its influencing factors]
    Hui Huang
    Department of Neurology, First Affiliated Hospital of Sun Yet sen University, Guangzhou 510080
    Zhongguo Zhong Xi Yi Jie He Za Zhi 24:1098-102. 2004
  8. ncbi request reprint Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity
    Yongqing Liu
    Departments of Microbiology and Pathology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
    J Gene Med 5:668-80. 2003
  9. pmc CD4+ Th1 cells promote CD8+ Tc1 cell survival, memory response, tumor localization and therapy by targeted delivery of interleukin 2 via acquired pMHC I complexes
    Hui Huang
    Research Unit, Saskatchewan Cancer Agency, Department of Oncology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Immunology 120:148-59. 2007
  10. ncbi request reprint IL-10 has a distinct immunoregulatory effect on naive and active T cell subsets
    Zhenmin Ye
    Research Unit, Health Research Division, Saskatchewan Cancer Agency, Department of Oncology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 4H4, Canada
    J Interferon Cytokine Res 27:1031-8. 2007

Collaborators

  • Xiao Li Yao
  • Cheng Zhang
  • Wei xi Zhang
  • Tai yun Liu
  • Song Lin Chen
  • Eric A Stone
  • BRET PAYSEUR
  • Yi Zhang
  • WILLIAM CHARLES NIERMAN
  • Wen Huang
  • J Craig Venter
  • Janet M Young
  • J Xiang
  • David Scadden
  • Michael L Metzker
  • Claire M Fraser
  • Evan E Eichler
  • Luis Fernandez
  • Kevin D Kreutter
  • Zhenmin Ye
  • Angelo A Cardoso
  • Jacquenilson Fernandes
  • Nadia Carlesso
  • Xueshu Zhang
  • Huiying Li
  • Leonor M Sarmento
  • Richard A Gibbs
  • Yongqing Liu
  • Yun an Tang
  • Yanping Chen
  • Carl Crysler
  • Bruce E Tomczuk
  • Mark R Player
  • Venkatraman Mohan
  • Christin Mumaw
  • Angelo Chora
  • Stephen Eisennagel
  • Bruce P Damiano
  • Filipa Cristina
  • Tianbao Lu
  • Guozhang Xu
  • Sonia Rodriguez
  • Karen Pollok
  • Joanne E Price
  • MARTIN MCMILLAN
  • Edward C Giardino
  • Bruce E Maryanoff
  • Malini Dasgupta
  • John C Spurlino
  • Michael J Ferkowicz
  • Lily Lee
  • Norman D Huebert
  • Mark Fitzgerald
  • Eugenia Cruz
  • Sharmila Patel
  • Barbara J Haertlein
  • Matthias Clauss
  • Sylvia Van Den Hurk
  • Shulin Xu
  • Siguo Hao
  • Hong Yu
  • Wu Shiun Hou
  • Thomas L Poulos
  • Elizabeth A Litzinger
  • Joumana Jamal
  • Marie Classon
  • John Gordon
  • Jotaro Igarashi
  • Lucio Miele
  • Richard B Silverman
  • William Gordon
  • Deming Sun
  • Maria J Tavares
  • Erik P Erdal
  • Mack L Flinspach
  • Jinying Yuan
  • Weiping Yang
  • Ana Limon
  • José Antonio Gómez-Vidal
  • Susan Bromberg
  • Donna M Muzny
  • Pieter J de Jong
  • David N Cooper
  • Shaying Zhao
  • Carlos Lopez-Otin
  • Kristian Stevens
  • Norbert Hubner
  • Klaus Lindpaintner
  • Inna Dubchak
  • Patrick Cahill

Detail Information

Publications20

  1. ncbi request reprint [Establishment of transgenic mouse model of familial amyotrophic lateral sclerosis and identification of the filial generation]
    Hui Huang
    Neurology Department, First Affiliated Hospital, Sun Yat Sen University, 510080, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:258-60, 265. 2006
    ..To establish transgenic mouse models of familial amyotrophic lateral sclerosis (FALS) and identify the genotype of the first filial generation...
  2. ncbi request reprint [Effect of transplantation of wild-type bone marrow stem cells in mouse model of familial amyotrophic lateral sclerosis]
    Hui Huang
    Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:562-6. 2006
    ..To determine the effects of wild-type mouse bone marrow stem cells transplants on survival time and motor functions in the human mutant SOD1-G93A mouse model of familial amyotrophic lateral sclerosis (ALS)...
  3. ncbi request reprint [Brain-derived neurotrophic factor induces rat bone marrow stromal cells to differentiate into neuron-like cells in vitro]
    Wen Huang
    Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou 510080, China
    Di Yi Jun Yi Da Xue Xue Bao 24:854-8. 2004
    ....
  4. ncbi request reprint [In vitro differentiation of rat bone mesenchymal stem cells into neuron-like cells induced by vitamin A acid etc]
    Yun an Tang
    Department of Toxicology, West China School of Public Health, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 34:377-80. 2003
    ..To explore the feasibility of inducing rat bone mesenchymal stem cells (BMSC) to differentiate into neuron-like cells with the use of Vitamin A acid, zinc and rat injured spinal cord extracts in vitro...
  5. ncbi request reprint A new dynamic model of CD8+ T effector cell responses via CD4+ T helper-antigen-presenting cells
    Jim Xiang
    Research Unit, Saskatchewan Cancer Agency, Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Immunol 174:7497-505. 2005
    ..These results have substantial implications for research in antitumor and other aspects of immunity...
  6. ncbi request reprint [The study of committed differentiation from adult rMSCs into neuron-like cells induced by Xiangdan injection in vitro]
    Hui Huang
    Neurology Department of the First Affiliated Hospital of Sun Yat sen University, Guangzhou
    Zhong Yao Cai 27:585-9. 2004
    ..To study the induction of Xiangdan Injection (XDI) on the committed differentiation into neuron from rMSCs...
  7. ncbi request reprint [Characteristics of oriented induction of xiangdan injection on differentiation of marrow mesenchymal stem cells into neurons and its influencing factors]
    Hui Huang
    Department of Neurology, First Affiliated Hospital of Sun Yet sen University, Guangzhou 510080
    Zhongguo Zhong Xi Yi Jie He Za Zhi 24:1098-102. 2004
    ..To study the effect of Xiangdan injection (XDI) in inducing adult SD rat marrow mesenchymal stem cells (rMSCs) orientedly differentiated into neuron-like cells, its characteristics and influencing factors were explored...
  8. ncbi request reprint Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity
    Yongqing Liu
    Departments of Microbiology and Pathology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
    J Gene Med 5:668-80. 2003
    ..Tumor antigen presentation by dendritic cells (DCs) to T cells in lymphoid organs is crucial for induction of antitumor immune responses. Fms-like tyrosine kinase 3 ligand (Flt3L) is a regulator of hematopoietic cell development...
  9. pmc CD4+ Th1 cells promote CD8+ Tc1 cell survival, memory response, tumor localization and therapy by targeted delivery of interleukin 2 via acquired pMHC I complexes
    Hui Huang
    Research Unit, Saskatchewan Cancer Agency, Department of Oncology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Immunology 120:148-59. 2007
    ..Taken together, these results will have important implications for designing adoptive T-cell immunotherapy protocols in treatment of solid tumors...
  10. ncbi request reprint IL-10 has a distinct immunoregulatory effect on naive and active T cell subsets
    Zhenmin Ye
    Research Unit, Health Research Division, Saskatchewan Cancer Agency, Department of Oncology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 4H4, Canada
    J Interferon Cytokine Res 27:1031-8. 2007
    ..The anergic CD4(+) T cells suppress T cell proliferation mainly through a CTLA-4-mediated pathway. The distinct role of IL-10 on T cell subsets may be useful in designing T cell-based immunotherapy of cancer and infectious diseases...
  11. doi request reprint Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif
    Kevin D Kreutter
    Johnson and Johnson Pharmaceutical Research and Development, Welsh and McKean Roads, Spring House, PA 19477, USA
    Bioorg Med Chem Lett 18:2865-70. 2008
    ..Optimization around this structural motif culminated in 14, which is a potent thrombin inhibitor (K(i)=1.2nM) that exhibits robust efficacy in canine anticoagulation and thrombosis models upon oral administration...
  12. ncbi request reprint [Dystrophin expression and pathology of diaphragm muscles of mdx mice after xenogenic bone marrow stem cell transplantation]
    Ya ni Zhang
    Department of Neurology, First Hospital of Sun Yat sen University, Guangzhou 510080, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:53-8. 2006
    ..To investigate the effect of bone marrow stem cell transplantation (BMT) on the diaphragm muscles of mdx mice, a mouse model of Duchenne muscular dystrophy (DMD)...
  13. ncbi request reprint Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases
    Huiying Li
    Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697 3900, USA
    Biochemistry 44:15222-9. 2005
    ..Here we report crystal structures and inhibition constants for bulkier dipeptide inhibitors bound to nNOS and eNOS that illustrate the important role played by residues near the entry to the active site in isoform selective inhibition...
  14. ncbi request reprint CD4-8- dendritic cells prime CD4+ T regulatory 1 cells to suppress antitumor immunity
    Xueshu Zhang
    Department of Oncology, University of Saskatchewan, Saskatoon, Canada
    J Immunol 175:2931-7. 2005
    ..Taken together, CD4-8- DCs stimulate development of IL-10-secreting CD4+ Tr1 cells that mediated immune suppression, whereas both CD4+8- and CD4-8+ DCs effectively primed animals for protective CD8+ CTL-mediated antitumor immunity...
  15. pmc Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation
    Leonor M Sarmento
    Center of Regenerative Medicine and Technology, Massachusetts General Hospital, Boston, MA, USA
    J Exp Med 202:157-68. 2005
    ....
  16. pmc Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes
    Hui Huang
    Department of Bioinformatics, Genome Therapeutics Corporation, Waltham, MA 02453, USA
    Genome Biol 5:R47. 2004
    ..Here, we investigate whether human disease genes differ significantly from their rodent orthologs with respect to their overall levels of conservation and their rates of evolutionary change...
  17. ncbi request reprint Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    Richard A Gibbs
    Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, MS BCM226, One Baylor Plaza, Houston, Texas 77030, USA lt http www hgsc bcm tmc edu
    Nature 428:493-521. 2004
    ....
  18. ncbi request reprint Synergistic effect of lymphotactin and interferon gamma-inducible protein-10 transgene expression in T-cell localization and adoptive T-cell therapy of tumors
    Hui Huang
    Research Unit, Saskatchewan Cancer Agency, Department of Microbiology, University of Saskatchewan, Saskatoon, Canada
    Int J Cancer 109:817-25. 2004
    ....
  19. ncbi request reprint Experimental study on cheng zai wan for treatment of necrosis of the femoral head
    Yanping Chen
    Institute of Orthopedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing 1000700
    J Tradit Chin Med 23:292-8. 2003
    ..It is suggested that Cheng Zai Wan has definite therapeutic effects on aseptic necrosis of the femoral head...
  20. pmc Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation
    Luis Fernandez
    Center of Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Exp Hematol 36:545-558. 2008
    ....