Yuejun Fu

Summary

Affiliation: Shanxi University
Country: China

Publications

  1. doi Potential adenovirus-mediated gene therapy of glioma cancer
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 32:11-8. 2010
  2. pmc Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 68:197-202. 2016
  3. doi AcMNPV-BmK IT improves the progeny virus production via baculovirus GP64 envelope fusion protein
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 38:1673-81. 2016
  4. pmc Effects of recombinant baculovirus AcMNPV-BmK IT on the formation of early cables and nuclear polymerization of actin in Sf9 cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 68:381-7. 2016
  5. pmc pEGFP-N1-mediated BmK CT expression suppresses the migration of glioma
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 65:533-9. 2013
  6. doi Regulation analysis of AcMNPV-mediated expression of a Chinese scorpion neurotoxin under the IE1, P10 and PH promoter in vivo and its use as a potential bio-insecticide
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 37:1929-36. 2015
  7. ncbi AcMNPV-mediated expression of BmK IT promotes the apoptosis of Sf9 cells and replication of AcMNPV
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, China
    Sheng Li Xue Bao 67:305-11. 2015
  8. doi Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Mol Biol Rep 41:3907-13. 2014
  9. doi Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: possible impact on glioma cell metastasis and chemo-resistance
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Int J Biochem Cell Biol 44:770-5. 2012
  10. doi Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    J Neurooncol 107:457-62. 2012

Collaborators

Detail Information

Publications27

  1. doi Potential adenovirus-mediated gene therapy of glioma cancer
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 32:11-8. 2010
    ....
  2. pmc Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 68:197-202. 2016
    ..This strategy can stand for a novel approach designated for the development of a new method for glioma therapy. ..
  3. doi AcMNPV-BmK IT improves the progeny virus production via baculovirus GP64 envelope fusion protein
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 38:1673-81. 2016
    ....
  4. pmc Effects of recombinant baculovirus AcMNPV-BmK IT on the formation of early cables and nuclear polymerization of actin in Sf9 cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 68:381-7. 2016
    ..AcMNPV-BmK IT delayed the formation of early cables of actin and nuclear F-actin and accelerated the clearance of actin in the nuclei. ..
  5. pmc pEGFP-N1-mediated BmK CT expression suppresses the migration of glioma
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Cytotechnology 65:533-9. 2013
    ..It represented an approach for developing a novel therapeutic agent-recombinant plasmid pEGFP-N1-BmK CT as an efficient and powerful adjuvant. ..
  6. doi Regulation analysis of AcMNPV-mediated expression of a Chinese scorpion neurotoxin under the IE1, P10 and PH promoter in vivo and its use as a potential bio-insecticide
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 37:1929-36. 2015
    ..To analyze the regulation mechanism of AcMNPV (Autographa californica multicapsid nucleopolyhedrovirus)-mediated expression of BmK IT under IE1, P10 and PH promoters in the larva of Heliothis armigera....
  7. ncbi AcMNPV-mediated expression of BmK IT promotes the apoptosis of Sf9 cells and replication of AcMNPV
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, China
    Sheng Li Xue Bao 67:305-11. 2015
    ..The results laid a foundation for further structural and functional analysis of BmK IT. ..
  8. doi Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Mol Biol Rep 41:3907-13. 2014
    ..These results indicated lithium chloride could decrease the proliferation and migration potential of C6 glioma cells harboring IDH2 mutation. ..
  9. doi Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: possible impact on glioma cell metastasis and chemo-resistance
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Int J Biochem Cell Biol 44:770-5. 2012
    ..These results demonstrated a functional model in which IDH mutations were closely interrelated with glioma progression and could hold some therapeutic implications for future human glioma treatment...
  10. doi Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    J Neurooncol 107:457-62. 2012
    ..We review the latest improvements of CTX-modified nanoparticle platforms which might enable development of more effective therapeutic agents in clinical treatment of glioma...
  11. doi Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Biotechnol Lett 34:441-6. 2012
    ..The HIF-1α pathway is probably a critical pathway for release of MMPs in the glioma cancer harboring IDH mutant...
  12. doi A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 34:9-17. 2012
    ..Our results suggested that the combination treatment of lithium and BmK CT may constitute a novel and potential strategy for HHG therapy...
  13. doi Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 410:218-23. 2011
    ....
  14. doi β-catenin as a potential key target for tumor suppression
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Int J Cancer 129:1541-51. 2011
    ....
  15. doi A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, People s Republic of China
    Biotechnol Lett 33:1309-17. 2011
    ..This is the first documentation of the structural mechanism of in the inhibition of glioma cell migration by BmK CT and may lead to the molecular design of specific inhibitors of MMP-2...
  16. doi Recombinant scorpion insect excitatory toxin BmK IT accelerates the growth of insect Spodoptera frugiperda 9 cells
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, People s Republic of China
    Mol Cell Biochem 351:93-8. 2011
    ..The findings presented in this study are essential for further study of this peptide...
  17. doi Glioma-derived mutations in IDH: from mechanism to potential therapy
    Yuejun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 397:127-30. 2010
    ....
  18. doi Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells
    Jun Du
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 35:861-70. 2013
    ..The adenovirus-mediated expression of BmK CT displayed a high activity in suppressing rat C6 glioma cells growth and invasion thereby suggesting that this recombinant adenovirus may be a powerful method for treating glioblastoma...
  19. ncbi Interaction of two classes of release factors from Euplotes octocarinatus
    Bao Feng Chai
    Key Laboratory of Chemical Biology and Molecular Engineering of Education Ministry, Shanxi University, Taiyuan 030006, China
    Yi Chuan Xue Bao 31:460-7. 2004
    ..Two classes of RFs are useful information in analysis of evolution of life-form and further elucidation of mechanism of translation termination of protein synthesis on ribosome...
  20. ncbi Synthesis, expression and purification of a type of chlorotoxin-like peptide from the scorpion, Buthus martensii Karsch, and its acute toxicity analysis
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, 030006, Taiyuan, People s Republic of China
    Biotechnol Lett 27:1597-603. 2005
    ..Western blot analysis demonstrated that this protein was rBmK CTa. Acute toxicity assay in mice demonstrated that the rBmK CTa had an LD(50) value of 4.3 mg kg(-1)...
  21. ncbi SfP53 and filamentous actin (F-actin) are the targets of viral pesticide AcMNPV-BmK IT (P10/PH) in host Spodoptera frugiperda 9 cells
    Leixi Cao
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Biotechnol Lett 38:2059-2069. 2016
    ..To analyze the anti-insect mechanism of viral pesticide AcMNPV-BmK IT(P10/PH) in the host Spodoptera frugiperda 9 (Sf9) cells...
  22. pmc Large-scale mass spectrometry-based analysis of Euplotes octocarinatus supports the high frequency of +1 programmed ribosomal frameshift
    Ruanlin Wang
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, China
    Sci Rep 6:33020. 2016
    ..Our data in this study provide very useful insight into the understanding of the molecular mechanism of +1 PRF. ..
  23. ncbi Baculovirus antiapoptotic protein P35 regulated the host apoptosis to enhance virus multiplication
    Yanyan Miao
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan, 030006, People s Republic of China
    Mol Cell Biochem 423:67-73. 2016
    ....
  24. doi Effect of location of the His-tag on the production of soluble and functional Buthus martensii Karsch insect toxin
    Cheng Gang Xu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Wucheng Road 36, Taiyuan, Shanxi 030006, PR China
    Protein Expr Purif 59:103-9. 2008
    ..This result indicated that the positioning of the His(6) tag has a key role in the production of soluble and functional BmK IT...
  25. ncbi [Soluble expression, purification and characterization of Bm K IT in Escherichia coli by intein-mediated system]
    Cheng Gang Xu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, China
    Sheng Wu Gong Cheng Xue Bao 23:989-94. 2007
    ..BmK IT(his6) was purified through Superdex 75 gel chromatography to more than 95% homogeneity. The purified protein has both correct secondary structure and insecticidal activity...
  26. ncbi Potential biochemical therapy of glioma cancer
    Li Tian Yin
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Biochem Biophys Res Commun 362:225-9. 2007
    ..These new findings may represent future directions for brain tumor studies and treatment...
  27. ncbi Therapeutic potential of chlorotoxin-like neurotoxin from the Chinese scorpion for human gliomas
    Yue Jun Fu
    Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Biotechnology, Shanxi University, Taiyuan 030006, PR China
    Neurosci Lett 412:62-7. 2007
    ..These results suggest that rBmK CTa may have potential therapeutic application in clinical treatment of human glioma. It represents an approach for developing a novel therapeutic agent...