Qiang Li

Summary

Affiliation: Shantou University Medical College
Country: China

Publications

  1. doi A sensitive rutin assay using a simple probe manganese sulfate based on its novel resonance light scattering decrease phenomenon
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Spectrochim Acta A Mol Biomol Spectrosc 71:344-9. 2008
  2. doi Determination of dextrin based on its self-aggregation by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Anal Chim Acta 635:202-6. 2009
  3. doi Resonance light scattering technique as a new tool to determine the binding mode of anticancer drug oridonin to DNA
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Eur J Med Chem 66:380-7. 2013
  4. doi A fluorescence switch sensor for 6-mercaptopurine detection based on gold nanoparticles stabilized by biomacromolecule
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 41:844-7. 2013
  5. doi Label-free fluorescence turn on detection of tiopronin with tunable dynamic range based on the ensemble of Alizarin Red S/copper ion
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Talanta 99:774-9. 2012
  6. doi A resonance light scattering sensor based on methylene blue-sodium dodecyl benzene sulfonate for ultrasensitive detection of guanine base associated mutations
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Anal Bioanal Chem 404:1673-9. 2012
  7. doi Alizarin red S/copper ion-based ensemble for fluorescence turn on detection of glutathione with tunable dynamic range
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 38:202-8. 2012
  8. doi A highly sensitive label-free resonance light scattering assay of carcinoembryonic antigen based on immune complexes
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Anal Chim Acta 747:99-105. 2012
  9. doi Protein-templated gold nanoclusters as fluorescence probes for the detection of methotrexate
    Zhanguang Chen
    Department of Chemistry, Shantou University, China
    Analyst 137:4356-61. 2012
  10. doi An aptamer based resonance light scattering assay of prostate specific antigen
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 36:35-40. 2012

Collaborators

  • Xi Chen
  • Junhui Chen
  • Zhen Wang
  • Maohuai Chen
  • Shaobin Wang
  • Wenhua Gao
  • Ping Li
  • Jin Zhang
  • Yi Zhu
  • Yan Huang
  • Liang Li
  • Dongyuan Zhao
  • Fang Chen
  • Jie Cai
  • Ya Li Han
  • Zhanguang Chen
  • Li Zhu
  • Yurui Peng
  • Sihua Qian
  • Jinbin Liu
  • Tianhe Song
  • Guoliang Liu
  • Guomin Zhang
  • Mingyao Wu
  • Guohui Sima
  • Fu Xiong
  • Yulong Lei
  • Jianping Yang
  • Zhan Guang Chen
  • Taiyu Zhang
  • Jian Hao
  • Jieyao Liang
  • Yanyu Wu
  • Xiangmin Xu
  • Yongge Wei
  • Wanjun Zhou
  • Xiaofeng Wei
  • Chunlin Lv
  • Rao Naumaan Nasim Khan
  • Youming Chen
  • Haiqiong Yuan
  • Cuimei Zhang
  • Xuan Shang
  • Jiahui Wu
  • ChangLong Li
  • Lidong Liu
  • Shuyan Wu
  • Ziping Cai
  • Yuejuan Lin
  • Fengji Li
  • Xiaopeng Huang
  • Guoming Zhang
  • Liwen Zheng
  • Zhisen Liang
  • Yuqing Li
  • Qinrong Wang
  • Bo Tu
  • Yonghui Deng
  • Yunpu Zhai
  • Dong Gu
  • Qingling Wu
  • Benjie Xu
  • Zhiming Guo
  • Jinhai Huang
  • Tai Yu Zhang
  • Jin Bin Liu
  • Weifeng Ding
  • Xuhong Liao

Detail Information

Publications34

  1. doi A sensitive rutin assay using a simple probe manganese sulfate based on its novel resonance light scattering decrease phenomenon
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Spectrochim Acta A Mol Biomol Spectrosc 71:344-9. 2008
    ..The assay is sensitive, rapid, inexpensive, practical and relatively free from interference generated by coexisting substances...
  2. doi Determination of dextrin based on its self-aggregation by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Anal Chim Acta 635:202-6. 2009
    ..The assay proposed owns the advantages of easy operation, rapidity, sensitivity and practicability. Three synthetic samples and three kinds of medicine samples were analyzed with satisfactory results...
  3. doi Resonance light scattering technique as a new tool to determine the binding mode of anticancer drug oridonin to DNA
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Eur J Med Chem 66:380-7. 2013
    ..The proposed RLS assay is not only an unprecedented one for primarily determine the binding mode of oridonin to DNA, but also a simple, sensitive, objective and straightforward method for the detection of ORI...
  4. doi A fluorescence switch sensor for 6-mercaptopurine detection based on gold nanoparticles stabilized by biomacromolecule
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 41:844-7. 2013
    ..And also it proved to be able to detect trace amount of 6-MP in real samples. The present assay largely improved the application of spectral methods in quantitative analysis of 6-MP...
  5. doi Label-free fluorescence turn on detection of tiopronin with tunable dynamic range based on the ensemble of Alizarin Red S/copper ion
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Talanta 99:774-9. 2012
    ..Thus, the assay shows great potential applications in the fields of pharmaceuticals and clinical analysis...
  6. doi A resonance light scattering sensor based on methylene blue-sodium dodecyl benzene sulfonate for ultrasensitive detection of guanine base associated mutations
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Anal Bioanal Chem 404:1673-9. 2012
    ..The ultrasensitive sensor allows simple, rapid, sensitive and selective detection of guanine base associated mutations, indicating its potential application in the medical field...
  7. doi Alizarin red S/copper ion-based ensemble for fluorescence turn on detection of glutathione with tunable dynamic range
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 38:202-8. 2012
    ....
  8. doi A highly sensitive label-free resonance light scattering assay of carcinoembryonic antigen based on immune complexes
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Anal Chim Acta 747:99-105. 2012
    ..And this method has many satisfying merits including label-free, sensitivity and high selectivity...
  9. doi Protein-templated gold nanoclusters as fluorescence probes for the detection of methotrexate
    Zhanguang Chen
    Department of Chemistry, Shantou University, China
    Analyst 137:4356-61. 2012
    ..9 ng mL(-1) at a signal-to-noise ratio of 3. The present sensor for methotrexate detection possessed a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results...
  10. doi An aptamer based resonance light scattering assay of prostate specific antigen
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Biosens Bioelectron 36:35-40. 2012
    ..This is the first report of the aptamer based RLS assay for PSA and it is also a significant application of instrumental analysis technique...
  11. doi Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, 515063, China
    Talanta 94:240-5. 2012
    ..3 ng mL(-1) at a signal-to-noise ratio of 3. The present sensor for ciprofloxacin detection possesses a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results...
  12. doi Sensitive and selective detection of glutathione based on resonance light scattering using sensitive gold nanoparticles as colorimetric probes
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Analyst 137:3132-7. 2012
    ....
  13. doi A resonance light-scattering off-on system for studies of the selective interaction between adriamycin and DNA
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Anal Bioanal Chem 402:2163-71. 2012
    ..It has also supplied a novel method for studying the sequence selectivity of DNA-targeted anticancer drugs and is a novel application of the RLS technique in analytical chemistry...
  14. doi A resonance light scattering quenching system for studying DNA sequence recognition of actinomycin D
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, 515063, China
    Analyst 137:722-8. 2012
    ..Results obtained from this work would supply a theoretical basis for improving anticancer activity and designing similar anticancer drugs...
  15. doi A new way to detect the interaction of DNA and anticancer drugs based on the decreased resonance light scattering signal and its potential application
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, 515063, China
    Analyst 136:3927-33. 2011
    ....
  16. doi DNA as a target for anticancer compounds screening directly by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, 515063, China
    Analyst 135:2653-60. 2010
    ..The conclusion indicated that the present method was direct, rapid, reliable and was another important innovation of the application of RLS technique...
  17. doi Use of Gemini surfactant in a one-step ellagic acid assay by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Daxue Road, Shantou 515063, Guangdong, China
    Talanta 82:885-91. 2010
    ..The mechanism of the reaction was also studied. This investigation could contribute to the research on the delivery and release of bioactive molecules by Gemini surfactants...
  18. doi Study on the interaction between hematoporphyrin monomethyl ether and DNA and the determination of hematoporphyrin monomethyl ether using the resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Spectrochim Acta A Mol Biomol Spectrosc 77:605-11. 2010
    ..The presented method was simple, sensitive and straightforward and could be a significant method in clinical analysis...
  19. ncbi Micro-determination of nucleic acids with a simple probe manganese chloride based on the fine enhanced resonance light scattering
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Spectrochim Acta A Mol Biomol Spectrosc 68:263-8. 2007
    ..0-10.0 microg ml(-1) for yRNA. The limits of detection (LOD, 3sigma) were 0.17, 0.13 and 0.53 ng ml(-1) for ctDNA, fsDNA and yRNA, respectively. Synthetic samples were determined satisfactorily...
  20. ncbi Development of a sensitive and rapid nucleic acid assay with tetraphenyl porphyrinatoiron chloride by a resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, People s Republic of China
    Luminescence 22:493-500. 2007
    ..The time savings make this method suitable for large routine analyses...
  21. ncbi A novel and selective assay for the quantitative analysis of molybdenum(VI) at nanogram level by resonance light scattering quenching technique
    Zhan Guang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Spectrochim Acta A Mol Biomol Spectrosc 70:290-6. 2008
    ....
  22. doi Determination of antibacterial quaternary ammonium compound in lozenges and human serum by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    J Pharm Biomed Anal 48:946-50. 2008
    ..9988 (n=9). The method was applied to the analysis of DQC in lozenges and human serum. The results indicated that the method was sensitive, simple, practical and useful in the clinical assay...
  23. doi Determination of nanograms of proteins based on decreased resonance light scattering of zwitterionic gemini surfactant
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Anal Biochem 384:337-42. 2009
    ....
  24. doi A novel curcumin assay with the metal ion Cu (II) as a simple probe by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Spectrochim Acta A Mol Biomol Spectrosc 72:518-22. 2009
    ..In this work, the RLS and fluorescence spectral characteristics of the chemicals, the optimum conditions of the reaction and the influencing factors were investigated...
  25. doi Screen anticancer drug in vitro using resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Talanta 77:1365-9. 2009
    ..Compared with the traditional MTT method, this method has high sensitivity, low detection limit and quite intuitive screening results which were identical to those obtained from the MTT colorimetric assay...
  26. doi High-sensitivity detection of polysaccharide using phosphodiesters quaternary ammonium salt as probe by decreased resonance light scattering
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, China
    Talanta 79:171-6. 2009
    ..Moreover, the mechanism of the reaction between PQAS and polysaccharide was investigated by RLS, fluorescence, and fluorescence lifetime spectra...
  27. ncbi Determination of antibacterial ofloxacin in human serum samples by a resonance light scattering technique with alizarin violet 3B
    Zhanguang Chen
    Department of Chemistry, Shantou University, China
    Anal Sci 25:891-6. 2009
    ..05-3.00 microg/ml. The detection limit (3sigma) was 0.021 microg/ml. The proposed method with high sensitivity, selectivity and reproducibility was satisfactorily applied to the determination of OFL in human serum...
  28. ncbi An instrument-based screening assay for DNA-targeted anticancer drugs using resonance light scattering
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou, China
    Comb Chem High Throughput Screen 13:383-92. 2010
    ..The proposed assay is a rapid, intuitive, and easy-to-conduct bioassay with good accuracy and reproducibility...
  29. doi Screening DNA-targeted anticancer drug in vitro based on the drug-conjugated DNA by resonance light scattering technique
    Zhanguang Chen
    Department of Chemistry, Shantou University, Daxue Road 243, Shantou 515063, China
    Biosens Bioelectron 25:1947-52. 2010
    ..In all, the proposed RLS is not only a simple, sensitive, objective and straightforward method, but also it is an unprecedented assay for primarily screening DNA-targeted anticancer drugs...
  30. ncbi Resonance light scattering spectroscopy study of interaction between norfloxacin and calf thymus DNA and its analytical application
    Zhanguang Chen
    Department of Chemistry, Shantou University, Shantou 515063, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 65:919-24. 2006
    ..Three synthetic samples of ctDNA were determined with satisfactory results...
  31. doi Organoimido-derivatized hexamolybdates with a remote carboxyl group: syntheses and structural characterizations
    Guohui Sima
    Department of Chemistry, Tsinghua University, Beijing 100084, PR China
    Inorg Chem 52:6551-8. 2013
    ..For compound 4, the 1D plus 2D structures are formed via three types of hydrogen bonding between the aromatic rings and the POM clusters of the two types of cluster anions with different orientations...
  32. doi Analyses of GATA4, NKX2.5, and TFAP2B genes in subjects from southern China with sporadic congenital heart disease
    Fu Xiong
    Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, Guangdong, China
    Cardiovasc Pathol 22:141-5. 2013
    ..The frequency of GATA4, NKX2.5, and TFAP2B mutations in subjects with congenital heart disease in southern China and the correlation between their genotype and congenital heart disease phenotype are not known...
  33. doi Direct triblock-copolymer-templating synthesis of ordered nitrogen-containing mesoporous polymers
    Jianping Yang
    Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Key Laboratory of Molecular Engineering of Polymers of the Chinese Ministry of Education, Fudan University, Shanghai 200433, People s Republic of China
    J Colloid Interface Sci 342:579-85. 2010
    ..The presence of nitrogen groups can also significantly improve the adsorption performance of Fe(III) ions...