Bin Li

Summary

Affiliation: Shanghai Institute of Applied Physics
Country: China

Publications

  1. doi request reprint Single-molecule imaging of DNA polymerase I (Klenow fragment) activity by atomic force microscopy
    J Chao
    Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    Nanoscale 8:5842-6. 2016
  2. pmc Enzymatic digestion of single DNA molecules anchored on nanogold-modified surfaces
    Junhong Lu
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, P, O, Box 800 204, Shanghai, 201800, China
    Nanoscale Res Lett 4:1029-34. 2009
  3. pmc Structural diversity of class 1 integrons and their associated gene cassettes in Klebsiella pneumoniae isolates from a hospital in China
    Bin Li
    CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e75805. 2013
  4. doi request reprint Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt
    Jing Yang
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
    J Immunol 194:4094-7. 2015
  5. pmc 60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells
    Yangyang Li
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 411 Hefei Road, Shanghai 200025, China
    J Biol Chem 288:15537-46. 2013
  6. doi request reprint Molecular threading and tunable molecular recognition on DNA origami nanostructures
    Na Wu
    Division of Physical Biology, and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    J Am Chem Soc 135:12172-5. 2013
  7. pmc The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3
    Zuojia Chen
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
    Immunity 39:272-85. 2013
  8. doi request reprint Probing tethered targets of a single biomolecular complex with atomic force microscopy
    Na Wu
    Division of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China
    J Mol Recognit 26:700-4. 2013
  9. pmc Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1
    Yayi Gao
    Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Clinical Immunology Center, Third Affiliated Hospital at Sun Yat Sen University, Guangzhou, 510630, China
    Proc Natl Acad Sci U S A 112:E3246-54. 2015
  10. pmc Genotypic analysis of Klebsiella pneumoniae isolates in a Beijing Hospital reveals high genetic diversity and clonal population structure of drug-resistant isolates
    Qi Wang
    CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e57091. 2013

Collaborators

  • Jun Hu
  • Fang Lin
  • Dan Li
  • Ming Ye
  • Qi Wang
  • Yi Zhang
  • Hui Sun
  • Chen Chen
  • Jing Zhang
  • Cui Hua Liu
  • Lu Wang
  • Jing Yang
  • Patrick C Y Woo
  • Xinyan Wang
  • Peng Xu
  • Jing Lin
  • Hua Jing
  • Yi Chen
  • Ze Zhang
  • Shiping Song
  • Qin Li
  • Andy Tsun
  • Zuojia Chen
  • Zhiyuan Li
  • Yayi Gao
  • Zhimei Gao
  • Ming Xing Liu
  • Yangyang Li
  • Na Wu
  • Jun Zhong
  • Ning Ning Dou
  • Xiaosheng Yang
  • Shi Ting Li
  • Yijun Fu
  • Lei Xia
  • Song Guo Zheng
  • Jia Nie
  • Na Duan
  • Xuerui Luo
  • Miranda Piccioni
  • Chunhai Fan
  • Jinsong Su
  • Xingfei Zhou
  • Shiting Li
  • Robert Guidoin
  • Denis Desaulniers
  • Ningjian Wang
  • Tian Tian
  • J Chao
  • Chunfang Zhu
  • Dongping Lin
  • Yingli Lu
  • Fangzhen Xia
  • Boren Jiang
  • Shuaiwei Wang
  • Lei Han
  • Gang Wei
  • Zhijun Han
  • Qingsi Wu
  • Jiayou Tang
  • Jijia Shen
  • Ying Wang
  • Zhengju Yao
  • Xin Cheng
  • Zhi Rui Zhao
  • Mark I Greene
  • Xiaomin Song
  • Daniel M Czajkowsky
  • Dongdong Zeng
  • Qingzhong Liu
  • Junhong Lu
  • Lai Xia
  • Xuming Hua
  • Massimiliano Visocchi
  • Haiqiang Qin
  • Wenchuan Zhang
  • Chongran Sun
  • Chaoxia Zhu
  • Jinhua Wang
  • Olexandr Bondarenko
  • Lin Hu
  • YONGBIN WANG
  • Mark Nutley
  • Zhen Cang
  • Yue Lu
  • Ying Meng
  • Guochao Shi
  • Bing Han
  • Weiping Tuc
  • Weihong Yang

Detail Information

Publications51

  1. doi request reprint Single-molecule imaging of DNA polymerase I (Klenow fragment) activity by atomic force microscopy
    J Chao
    Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    Nanoscale 8:5842-6. 2016
    ..Upon completion of these actions, a double-stranded DNA molecule was formed. Furthermore, the direction of KF activities was captured and then confirmed by shifting the KF binding sites on the template DNA. ..
  2. pmc Enzymatic digestion of single DNA molecules anchored on nanogold-modified surfaces
    Junhong Lu
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, P, O, Box 800 204, Shanghai, 201800, China
    Nanoscale Res Lett 4:1029-34. 2009
    ..We demonstrate that by using Dip-Pen Nanolithography, individual DNA molecules attached to modified mica surfaces can be efficiently digested by DNase I...
  3. pmc Structural diversity of class 1 integrons and their associated gene cassettes in Klebsiella pneumoniae isolates from a hospital in China
    Bin Li
    CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e75805. 2013
    ..The aim of this study was to characterize the structural diversity of class 1 integrons and their associated gene cassettes in K. pneumoniae isolates from hospital settings...
  4. doi request reprint Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt
    Jing Yang
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
    J Immunol 194:4094-7. 2015
    ..Thus, USP4 could be a novel therapeutic target for the treatment of Th17-modulated autoimmune diseases. ..
  5. pmc 60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells
    Yangyang Li
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 411 Hefei Road, Shanghai 200025, China
    J Biol Chem 288:15537-46. 2013
    ..Our results reveal a novel pathway by which TIP60 and ThPOK synergistically suppresses Eomes function and IFNγ production, which could contribute to the regulation of inflammation...
  6. doi request reprint Molecular threading and tunable molecular recognition on DNA origami nanostructures
    Na Wu
    Division of Physical Biology, and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    J Am Chem Soc 135:12172-5. 2013
    ..Our finding reveals a previously overlooked critical design feature that should provide new interpretations to previous experiments and new opportunities for the construction of origami structures with new functional capabilities. ..
  7. pmc The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3
    Zuojia Chen
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
    Immunity 39:272-85. 2013
    ....
  8. doi request reprint Probing tethered targets of a single biomolecular complex with atomic force microscopy
    Na Wu
    Division of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China
    J Mol Recognit 26:700-4. 2013
    ..We identify the functionally useful tether lengths for these investigations, which are also expected to prove useful in the construction and further application of DNA origami in bio-nanotechnology studies...
  9. pmc Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1
    Yayi Gao
    Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Clinical Immunology Center, Third Affiliated Hospital at Sun Yat Sen University, Guangzhou, 510630, China
    Proc Natl Acad Sci U S A 112:E3246-54. 2015
    ..These findings establish a previously unidentified mechanism regulating FOXP3 stability during inflammation and reveal a pathway for potential therapeutic modulation and intervention in inflammatory diseases. ..
  10. pmc Genotypic analysis of Klebsiella pneumoniae isolates in a Beijing Hospital reveals high genetic diversity and clonal population structure of drug-resistant isolates
    Qi Wang
    CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e57091. 2013
    ..We thus conducted this prospective study to analyze the molecular epidemiology of K. pneumoniae isolates from patients being treated in the 306 Hospital in Beijing, China for the period of November 1, 2010-October 31, 2011...
  11. doi request reprint USP22 is a positive regulator of NFATc2 on promoting IL2 expression
    Yayi Gao
    Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    FEBS Lett 588:878-83. 2014
    ..Our findings thus unveil a previously uncharacterized positive regulator of NFATc2, suggesting that targeting the deubiquitinase activity of USP22 could have therapeutic benefit to control IL2 expression and T cell function. ..
  12. pmc PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation
    Zhiyuan Li
    From the Unit of Molecular Immunology, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
    J Biol Chem 289:26872-81. 2014
    ....
  13. doi request reprint Facilitating the pickup of individual DNA molecules by AFM nanomanipulation with tips mechanically worn on bare mica
    Na Duan
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, People s Republic of China
    Microsc Res Tech 75:638-42. 2012
    ..It was demonstrated that bare mica was superior to APTES-modified mica to keep the tip clean while wearing, which was crucial for DNA pickup during AFM nanomanipulation...
  14. ncbi request reprint Fatal complications following microvascular decompression: could it be avoided and salvaged?
    Lei Xia
    Department of Neurosurgery, Xinhua Hospital The Cranial Nerve Disease Center of Shanghai, Shanghai Jiaotong University School of Medicine, 1665 KongJiang Rd, Shanghai, 200092, China
    Neurosurg Rev . 2016
    ..Once a cerebellar hematoma is confirmed, an emergency surgery should not be hesitated. A prompt evacuation of the hematomas followed by a dual ventricular drainage via both the frontal horns may save the patient...
  15. pmc Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein Regulates the Function of Regulatory T Cells
    Xuerui Luo
    From the Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    J Biol Chem 290:28675-82. 2015
    ..This finding has implications for developing PARP-1 inhibitors as potential agents for the prevention and treatment of autoimmune diseases. ..
  16. doi request reprint Kaempferol enhances the suppressive function of Treg cells by inhibiting FOXP3 phosphorylation
    Fang Lin
    Unit of Molecular Immunology, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
    Int Immunopharmacol 28:859-65. 2015
    ....
  17. doi request reprint The Significance of Abnormal Muscle Response Monitoring During Microvascular Decompression for Hemifacial Spasm
    Ming Xing Liu
    Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China
    Acta Neurochir Suppl 124:297-301. 2017
    ..In order to better use this intraoperative electrophysiology, it is necessary to further address the relationship between AMR and postoperative results...
  18. doi request reprint Management of symptomatic hemifacial spasm or trigeminal neuralgia
    Ming Xing Liu
    Department of Neurosurgery, Xinhua Hospital The Cranial Nerve Disease Center of Shanghai, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China
    Neurosurg Rev 39:411-8. 2016
    ..In some cases, a microvascular decompression process might be unnecessary afterward, but the entire nerve root should be checked to exclude any vessel in contact with. ..
  19. doi request reprint Confined water nanofilm promoting nonenzymatic degradation of DNA molecules
    Ming Ye
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, P R China
    J Phys Chem B 115:2754-8. 2011
    ..Careful analysis indicated that it was the formation of a water/vapor interface in the water nanofilm that played a major role in promoting DNA degradation...
  20. pmc Synergy between IL-6 and TGF-β signaling promotes FOXP3 degradation
    Zhimei Gao
    The Bioengineering Graduate Program, School of Life Sciences, Fudan University, Shanghai, 200433, China
    Int J Clin Exp Pathol 5:626-33. 2012
    ....
  21. pmc CD151 mediates netrin-1-induced angiogenesis through the Src-FAK-Paxillin pathway
    Xiaosheng Yang
    Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    J Cell Mol Med 21:72-80. 2017
    ....
  22. doi request reprint The Triplex BioValsalva Prostheses To Reconstruct the Aortic Valve and the Aortic Root
    Yijun Fu
    Key Laboratory of Textile Science and Technology of the Ministry of Education, College of Textile, Donghua University, Shanghai, China
    J Long Term Eff Med Implants 26:49-78. 2016
    ..The BioValsalva prosthesis allows the Bentall operation to be used in patients whose aortic valve cannot be spared. ..
  23. doi request reprint In situ monitoring of single molecule binding reactions with time-lapse atomic force microscopy on functionalized DNA origami
    Na Wu
    Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China
    Nanoscale 3:2481-4. 2011
    ..Single streptavidin molecules bound to specifically biotinyated DNA origami were simply counted as a function of time to obtain a direct measure of the binding rate...
  24. ncbi request reprint A cancer protein microarray platform using antibody fragments and its clinical applications
    Shiping Song
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China
    Mol Biosyst 3:151-8. 2007
    ..More importantly, clinical applications of our F(ab')2 microarray platform for upwards of 100 patient serum samples clearly show its potential in cancer diagnostics...
  25. doi request reprint Papillary meningioma: an aggressive variant meningioma with clinical features and treatment: a retrospective study of 10 cases
    Bin Li
    a 1 Department of Neurosurgery Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
    Int J Neurosci 126:878-87. 2016
    ..Papillary meningioma is a rare subtype of malignant meningiomas. The aim of this retrospective study was to investigate the clinical, radiological, histopathological features and prognosis for papillary meningioma at our institutions...
  26. pmc USP21 prevents the generation of T-helper-1-like Treg cells
    Yangyang Li
    Key Laboratory of Molecular Virology and Immunology, CAS Center for Excellence in Molecular Cell Science, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
    Nat Commun 7:13559. 2016
    ..USP21 stabilizes FOXP3 protein by mediating its deubiquitination and maintains the expression of Treg signature genes. Our results demonstrate how USP21 prevents FOXP3 protein depletion and controls Treg lineage stability in vivo...
  27. pmc FOXP3+ regulatory T cells and their functional regulation
    Zhiyuan Li
    Unit of Molecular Immunology, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China
    Cell Mol Immunol 12:558-65. 2015
    ..Here, we summarize these intriguing findings, and provide insight into their potential use or manipulation during Treg cell therapy for the treatment of autoimmune diseases, graft-versus-host disease (GVHD) and cancer. ..
  28. pmc MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression
    Dan Li
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Sci Rep 5:14615. 2015
    ..This finding reveals a GATA3/miR-125a-5p/IL-6R and STAT3/FOXP3 regulatory pathway, which determines how Treg cells respond to inflammatory IL-6-rich conditions. ..
  29. pmc Analysis of drug resistance determinants in Klebsiella pneumoniae isolates from a tertiary-care hospital in Beijing, China
    Bin Li
    Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 7:e42280. 2012
    ..The rates of multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) isolates among Enterobacteriaceae isolates, particularly Klebsiella pneumoniae, have risen substantially worldwide...
  30. doi request reprint Ubiquitination signals critical to regulatory T cell development and function
    Zuojia Chen
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 411 Hefei Road, Shanghai, 200025, China
    Int Immunopharmacol 16:348-52. 2013
    ..Understanding how FOXP3 activity is regulated by ubiquitination and deubiquitination under molecular level will promote regulatory T cell therapy for treating inflammation in autoimmune disease, infection, transplantation and cancer...
  31. doi request reprint Factors Affecting Hospital Mortality in Patients with Esophagogastric Anastomotic Leak: A Retrospective Study
    Bin Li
    Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
    World J Surg 40:1152-7. 2016
    ..We aimed to clarify the association between anastomotic leak and leak-associated mortality to assist decision-making and reduce hospital mortality...
  32. ncbi request reprint Hypothalamic-Pituitary-Gonadal Axis in Aging Men and Women: Increasing Total Testosterone in Aging Men
    Fangzhen Xia
    Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
    Neuroendocrinology . 2016
    ..However, how aging changes these hormones is not clear. This study examined the natural alterations in the hypothalamic-pituitary-gonadal (HPG) axis in aging men and women in China...
  33. pmc Acupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain
    Tian Tian
    Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    Sci Rep 6:19714. 2016
    ....
  34. pmc GlnR negatively regulates the transcription of the alanine dehydrogenase encoding gene ald in Amycolatopsis mediterranei U32 under nitrogen limited conditions via specific binding to its major transcription initiation site
    Ying Wang
    Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China Department of Microbiology, School of Life Science, Fudan University, Shanghai, China
    PLoS ONE 9:e104811. 2014
    ..Therefore, one may easily conclude that GlnR represses the transcription of ald via specific binding to the GlnR binding sites, which obviously blocks the transcription initiation from aldP2 and therefore reduces ald transcripts. ..
  35. ncbi request reprint [Single-molecule detection and characterization of DNA replication based on DNA origami]
    Qi Wang
    Physical Biology Laboratory, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China E mail
    Nan Fang Yi Ke Da Xue Xue Bao 34:1235-40. 2014
    ..To investigate single-molecule detection and characterization of DNA replication...
  36. doi request reprint Regulatory T-cell differentiation and their function in immune regulation
    Miranda Piccioni
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institute Pasteur of Shanghai, Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200025, China
    Adv Exp Med Biol 841:67-97. 2014
    ..This chapter highlights the most recent discoveries in the field of Treg biology, focusing on the development and role of this cell subset in the maintenance of immune balance...
  37. pmc Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3
    Jing Zhang
    Key Laboratory of Molecular Virology and Immunology, Unit of Molecular Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 411 Hefei Road, Shanghai 200025, China
    J Biol Chem 288:9373-82. 2013
    ..We propose that this pathway forms an important signaling loop that stabilizes the expression of GATA3 in Treg cells...
  38. pmc The nine-year changes of the incidence and characteristics of metabolic syndrome in China: longitudinal comparisons of the two cross-sectional surveys in a newly formed urban community
    Boren Jiang
    Department of Endocrinology and Metabolism, Shanghai Ninth People s Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, 200011, China
    Cardiovasc Diabetol 15:84. 2016
    ..To assess the 9-year changes of the incidence and characteristics of metabolic syndrome (MetS) in Chinese community under the background of dramatically changed environment...
  39. pmc Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function
    Xiaomin Song
    State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China 200031
    Cell Rep 1:665-75. 2012
    ..Overall, the regulatory machinery involving homooligomerization, acetylation, and heteroassociation has been dissected, defining atomic insights into the biological and pathological characteristics of the FOXP3 complex...
  40. pmc Virulence characteristic and MLST-agr genetic background of high-level mupirocin-resistant, MRSA isolates from Shanghai and Wenzhou, China
    Qingzhong Liu
    Department of Clinical Laboratory, Shanghai First People s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
    PLoS ONE 7:e37005. 2012
    ..Our results indicated that MuH MRSA strains from two different geographic regions of China have differences in distribution of some virulence genes, while their major MLST-agr genetic backgrounds were accordant...
  41. ncbi request reprint Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation
    Bin Li
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    J Am Chem Soc 129:6668-9. 2007
  42. doi request reprint Th17 cells in autoimmune diseases
    Lei Han
    Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai, 200040, China
    Front Med 9:10-9. 2015
    ....
  43. doi request reprint The Gelweave Valsalva Graft to Better Reconstruct the Anatomy of the Aortic Root
    Yijun Fu
    Key Laboratory of Textile Science and Technology of the Ministry of Education, College of Textile, Donghua University, Shanghai, China
    J Long Term Eff Med Implants 26:97-121. 2016
    ..The Gelweave Valsalva graft allows the Bentall operation to be standardized, and it provides a potential for longer durability with reduced adverse events...
  44. doi request reprint Netrin-1 overexpression improves neurobehavioral outcomes and reduces infarct size via inhibition of the notch1 pathway following experimental stroke
    Xiaosheng Yang
    Department of Neurosurgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Address 1665 Kongjiang Road, Yangpu District, Shanghai, 200092, China
    J Neurosci Res . 2017
    ..These results demonstrate that early administration of Netrin-1 can is an effective therapeutic approach for improving outcome after stroke. © 2017 Wiley Periodicals, Inc...
  45. doi request reprint Relationship between differential retention of Escherichia coli and Enterococcus faecalis and variations in enzyme activity in the scallop Patinopecten yessoensis
    Bin Li
    Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
    Mar Pollut Bull 60:1600-5. 2010
    ..In conclusion, the mass retention of gut microflora in P. yessoensis is positively correlated with digestive enzymes activity and negatively correlated with ACP activity in the hemocyte...
  46. doi request reprint High prevalence of CTX-M β-lactamases in faecal Escherichia coli strains from healthy humans in Fuzhou, China
    Bin Li
    Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Scand J Infect Dis 43:170-4. 2011
    ..The aim of this study was to investigate the prevalence and genetic environments of bla(CTX-M) among faecal Escherichia coli obtained from healthy persons in a region of China...
  47. doi request reprint Preoperative risk factors influencing the incidence of postoperative sepsis in human immunodeficiency virus-infected patients: a retrospective cohort study
    Jinsong Su
    Department of Surgery, Shanghai Public Health Clinical Center affiliated with Fudan University, 2901 Caolang Road, Jinshan District, Shanghai, 201508, China
    World J Surg 37:774-9. 2013
    ..We aimed to investigate the preoperative risk factors that affect the incidence of sepsis after surgery in HIV-infected patients...
  48. ncbi request reprint [Comparing microbial community of high ammonia wastewater and municipal sewage in a partial nitrification system]
    Zhi Rui Zhao
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
    Huan Jing Ke Xue 34:1448-56. 2013
    ..The copy number of AOB was higher than the copy number of NOB in sewage treatment process by two orders of magnitude...
  49. doi request reprint Controllable broadband nonlinear optical response of graphene dispersions by tuning vacuum pressure
    Xin Cheng
    Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China
    Opt Express 21:16486-93. 2013
    ..This work affords a simple method to distinguish the nonlinear scattering and absorption mechanisms for NLO nanomaterials. ..
  50. doi request reprint Management of Bilateral Hemifacial Spasm with Microvascular Decompression
    Ning Ning Dou
    Department of Neurosurgery, Xinhua Hospital The Cranial Nerve Disease Center of Shanghai, Shanghai Jiaotong University School of Medicine, Shanghai, China
    World Neurosurg 87:640-5. 2016
    ..Although microvascular decompression (MVD) is widely accepted as effective therapy for HFS, the etiology and surgical treatment of bilateral HFS are seldom addressed. We report our experience with MVD for patients with bilateral HFS...
  51. pmc Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma
    Xiao qiang Wang
    Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Oncotarget 7:2354-66. 2016
    ..In summary, our study suggests that TREM2 may work as an oncogene and a new effective therapeutic target for glioma treatment. ..