Lin Lu

Summary

Country: China

Publications

  1. doi request reprint Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs.
    Yu Hu He
    Arterioscler Thromb Vasc Biol 37:717-729. 2017
  2. doi request reprint The anti-inflammatory vasostatin-2 attenuates atherosclerosis in ApoE-/- mice and inhibits monocyte/macrophage recruitment
    Weixin Xiong
    Lin Lu, Department of Cardiology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, P R China, Tel 86 21 64370045, Fax 86 21 64457177, E mail
    Thromb Haemost 117:401-414. 2017
  3. pmc Association of increased serum glycated albumin levels with low coronary collateralization in type 2 diabetic patients with stable angina and chronic total occlusion
    Ying Shen
    Department of Cardiology, Shanghai Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Cardiovasc Diabetol 12:165. 2013
  4. pmc Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion
    Zhen Sun
    Department of Cardiology, Shanghai Ruijin Hospital, Shanghai 200025, China
    J Zhejiang Univ Sci B 14:705-12. 2013
  5. doi request reprint Impact of elevated serum glycated albumin levels on contrast-induced acute kidney injury in diabetic patients with moderate to severe renal insufficiency undergoing coronary angiography
    Feng Hua Ding
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, People s Republic of China
    Int J Cardiol 167:369-73. 2013
  6. doi request reprint The C161T polymorphism in the peroxisome proliferator-activated receptor gamma gene (PPARγ) is associated with risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Ruijin Second Road 197, Shanghai 200025, China
    Mol Biol Rep 40:3101-12. 2013
  7. pmc Screening for significant atherosclerotic renal artery stenosis with a regression model in patients undergoing transradial coronary angiography/intervention
    Li Jin Pu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    J Zhejiang Univ Sci B 13:631-7. 2012
  8. ncbi request reprint Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients
    Wei Wang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 124:66-71. 2011
  9. doi request reprint Increased glycated albumin and decreased esRAGE levels are related to angiographic severity and extent of coronary artery disease in patients with type 2 diabetes
    Lin Lu
    Department of Cardiology, Rui Jin Hospital, 197 Rui Jin Road II, Shanghai 200025, PR China
    Atherosclerosis 206:540-5. 2009
  10. doi request reprint The Connexin37 gene C1019T polymorphism and risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
    Arch Med Res 45:21-30. 2014

Collaborators

  • Wei Feng Shen
  • Qi Zhang
  • Yan Liu
  • Ying Shen
  • Wei Jin
  • Jian Hu
  • Ke Yang
  • Ruiyan Zhang
  • Wei Wang
  • Raffaele De Caterina
  • WenQuan Niu
  • Jing Liu
  • Min Xu
  • Zhijun Wu
  • Jia Teng Sun
  • Qiujing Chen
  • Qiu Jing Chen
  • Yuqing Lou
  • Rong Tao
  • Ling Jie Wang
  • Feng Hua Ding
  • Xiao Qun Wang
  • Zhen Kun Yang
  • Li Jin Pu
  • Zheng bin Zhu
  • Tian qi Zhu
  • Guoping Lu
  • Jiumei Cao
  • Liang Geng
  • Weixin Xiong
  • Yu Hu He
  • Zhu Hui Liu
  • Yong Wang
  • Qin Fan
  • Wei Xin Xiong
  • Min Wang
  • Xiao Xiang Yan
  • Zhen Sun
  • Zheng Kun Yang
  • Xue Ying Cai
  • Yuan Ying
  • Cao Jin
  • Jian Lei Zheng
  • Wen Ruan
  • Bao Zhang
  • Xiaoqun Wang
  • Jian Zhang
  • Daopeng Dai
  • Wen Qi Pan
  • Rui Xi
  • Hang Zhang
  • Xiaochen Hao
  • Fang Wang
  • Jing wei Ni
  • Yan Ping Wang
  • Li Ping Wu
  • Hong Juan Liu
  • Qi Hong Wu
  • Lu Xue
  • Jing Yan Mao
  • Nan Chen
  • Jin Zhou Zhu
  • Heng Ma
  • Jun Yang
  • Jie Gao
  • Xiaoxiang Yan
  • Hui Han
  • Huan Zhang
  • Dao Peng Dai
  • Haihui Sheng
  • Yanjia Chen
  • Xiaochun Qiu
  • Xin Chen
  • Xiuxiu Su
  • Gang Gu
  • Hui Geng Jin
  • Jie Shen
  • Liang Ping Zhao
  • Yucai Xie
  • An Kang Lu
  • Jian Ping Qiu
  • Ya nan Wang
  • Yu Song He
  • Haibo Wang
  • Tianqi Zhu
  • Jingwei Ni
  • Feng Ru Zhang
  • Lingjie Wang
  • Qiu J Chen
  • Qiu Jin Chen

Detail Information

Publications54

  1. doi request reprint Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs.
    Yu Hu He
    Arterioscler Thromb Vasc Biol 37:717-729. 2017
    ..Serum HMGB2 levels were associated with ISR in patients. HMGB2 promoted neointimal hyperplasia in mice with arterial wire injury through reactive oxygen species activation...
  2. doi request reprint The anti-inflammatory vasostatin-2 attenuates atherosclerosis in ApoE-/- mice and inhibits monocyte/macrophage recruitment
    Weixin Xiong
    Lin Lu, Department of Cardiology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, P R China, Tel 86 21 64370045, Fax 86 21 64457177, E mail
    Thromb Haemost 117:401-414. 2017
    ..In conclusion, the Chromogranin A-derived VS-2 attenuates atherosclerosis in apoE-/- mice and, in addition to its anti-inflammatory property, also acts as an inhibitor in monocyte/macrophage recruitment...
  3. pmc Association of increased serum glycated albumin levels with low coronary collateralization in type 2 diabetic patients with stable angina and chronic total occlusion
    Ying Shen
    Department of Cardiology, Shanghai Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Cardiovasc Diabetol 12:165. 2013
    ..We investigated whether serum glycated albumin (GA) levels are related to coronary collateralization in type 2 diabetic patients with chronic total occlusion...
  4. pmc Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion
    Zhen Sun
    Department of Cardiology, Shanghai Ruijin Hospital, Shanghai 200025, China
    J Zhejiang Univ Sci B 14:705-12. 2013
    ..We sought to determine which clinical and angiographic variables are associated with collateral development in patients with stable angina and chronic total coronary occlusion...
  5. doi request reprint Impact of elevated serum glycated albumin levels on contrast-induced acute kidney injury in diabetic patients with moderate to severe renal insufficiency undergoing coronary angiography
    Feng Hua Ding
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, People s Republic of China
    Int J Cardiol 167:369-73. 2013
    ....
  6. doi request reprint The C161T polymorphism in the peroxisome proliferator-activated receptor gamma gene (PPARγ) is associated with risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Ruijin Second Road 197, Shanghai 200025, China
    Mol Biol Rep 40:3101-12. 2013
    ..11, P = 0.913). Taken together, our results revealed the PPARγ C161T polymorphism might play a moderate protective effect on developing CAD among Chinese, but not among Caucasians...
  7. pmc Screening for significant atherosclerotic renal artery stenosis with a regression model in patients undergoing transradial coronary angiography/intervention
    Li Jin Pu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    J Zhejiang Univ Sci B 13:631-7. 2012
    ..We investigated whether the presence of significant ARAS (luminal diameter narrowing ≥70%) could be predicted using a logistic regression model before coronary angiography/intervention...
  8. ncbi request reprint Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients
    Wei Wang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 124:66-71. 2011
    ..3 with early-onset and severity of CAD in Chinese patients with and without type 2 diabetes, and to determine the possible impact of rs1333049 on glucose metabolism and inflammation pathways...
  9. doi request reprint Increased glycated albumin and decreased esRAGE levels are related to angiographic severity and extent of coronary artery disease in patients with type 2 diabetes
    Lin Lu
    Department of Cardiology, Rui Jin Hospital, 197 Rui Jin Road II, Shanghai 200025, PR China
    Atherosclerosis 206:540-5. 2009
    ....
  10. doi request reprint The Connexin37 gene C1019T polymorphism and risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
    Arch Med Res 45:21-30. 2014
    ..However, previous studies yielded conflicting results. In the current study, a comprehensive meta-analysis was performed to investigate whether the C1019T polymorphism is associated with CAD risk...
  11. doi request reprint Insertion/insertion genotype of α(2B)-adrenergic receptor gene polymorphism is associated with silent myocardial ischemia in patients with type 2 diabetes mellitus
    Qiu Jing Chen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Clin Biochem 43:1201-4. 2010
    ..We investigated whether α(2)-adrenergic receptor (AR) polymorphisms (α(2A)-AR, α(2B)-AR and α(2C)-AR gene) affected silent myocardial ischemia (SMI) in patients with type 2 diabetes mellitus (T2DM)...
  12. pmc Interactive association of five candidate polymorphisms in Apelin/APJ pathway with coronary artery disease among Chinese hypertensive patients
    Wei Jin
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    PLoS ONE 7:e51123. 2012
    ....
  13. doi request reprint C1q/TNF-related protein-1: an adipokine marking and promoting atherosclerosis
    Lin Lu
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People s Republic of China Institute of Cardiovascular Diseases, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Eur Heart J 37:1762-71. 2016
    ..We investigated the association of the adipokine C1q/TNF-related protein (CTRP) 1 with coronary artery disease (CAD), and the biological vascular effects of CTRP1...
  14. ncbi request reprint Intra-coronary administration of soluble receptor for advanced glycation end-products attenuates cardiac remodeling with decreased myocardial transforming growth factor-beta1 expression and fibrosis in minipigs with ischemia-reperfusion injury
    Lin Lu
    Department of Cardiology, Ruijin Hospital, Institute of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 123:594-8. 2010
    ..This study aimed to evaluate the effects of intra-coronary administration of sRAGE on left ventricular function and myocardial remodeling in a porcine model of ischemia-reperfusion (I/R) injury...
  15. pmc Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    PLoS ONE 8:e70885. 2013
    ..Therefore, we undertook a comprehensive meta-analysis to more precisely evaluate the influence of this polymorphism on CAD and potential biases...
  16. doi request reprint Association of increased S100B, S100A6 and S100P in serum levels with acute coronary syndrome and also with the severity of myocardial infarction in cardiac tissue of rat models with ischemia-reperfusion injury
    Xue Ying Cai
    Department of Cardiology, Rui Jin Hospital, Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Atherosclerosis 217:536-42. 2011
    ..We aim to check if serum levels of receptor for advanced glycation endproduct (RAGE) ligands S100B, S100A6 and S100P were related to myocardial injury in acute coronary syndrome (ACS)...
  17. doi request reprint Estrogen induces cardioprotection in male C57BL/6J mice after acute myocardial infarction via decreased activity of matrix metalloproteinase-9 and increased Akt-Bcl-2 anti-apoptotic signaling
    Jiumei Cao
    Department of Cardiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P R China
    Int J Mol Med 28:231-7. 2011
    ..In vitro studies using H9C2 cells under simulated ischemia re-oxygenation treatment further support the role of estrogen receptor β in estrogen-mediated cardioprotection through the Akt-Bcl-2 signaling pathway...
  18. pmc Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats
    Lin Lu
    Department of Cardiology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
    J Zhejiang Univ Sci B 12:652-9. 2011
    ..This study aimed to assess the effect of atorvastatin on diabetic nephropathy via soluble RAGE (sRAGE) and RAGE expressions in the rat kidney...
  19. doi request reprint MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4
    Ke Yang
    Department of Cardiology, Rui Jin Hospital, Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    FEBS Lett 585:854-60. 2011
    ..Over-expression of miR-146a may be useful in the prevention and treatment of atherosclerosis...
  20. pmc Chromosome 9p21.3 polymorphism in a Chinese Han population is associated with angiographic coronary plaque progression in non-diabetic but not in type 2 diabetic patients
    Wei Wang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Cardiovasc Diabetol 9:33. 2010
    ..We sought to explore the association of variant rs1333049 on chromosome 9p21.3 with coronary artery disease (CAD) and angiographic plaque progression in non-diabetic and type 2 diabetic patients...
  21. ncbi request reprint Clinical relevance of angiographic coronary collaterals during primary coronary intervention for acute ST-elevation myocardial infarction
    Ying Shen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 127:66-71. 2014
    ..We sought to investigate the impact of early coronary collateralization, as evidenced by angiography, on myocardial reperfusion and outcomes after primary percutaneous coronary intervention (PCI)...
  22. pmc Association of natriuretic peptide polymorphisms with left ventricular dysfunction in southern Han Chinese coronary artery disease patients
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China
    Int J Clin Exp Pathol 7:7148-57. 2014
    ..The aim of this study was to investigate the relationship between natriuretic peptide polymorphisms and risk of LVD in CAD patients...
  23. doi request reprint C1q/TNF-related protein 1 links macrophage lipid metabolism to inflammation and atherosclerosis
    Xiao Qun Wang
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China Institute of Cardiovascular Diseases, Shanghai Jiao Tong University, Shanghai, PR China
    Atherosclerosis 250:38-45. 2016
    ..In this study, we sought to investigate the changes in CTRP expression levels during vital biological processes in macrophages and their relation to inflammatory responses...
  24. doi request reprint Impact of coronary collateral circulation on angiographic in-stent restenosis in patients with stable coronary artery disease and chronic total occlusion
    Zhen Kun Yang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Int J Cardiol 227:485-489. 2017
    ....
  25. pmc Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis
    Yan Liu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    PLoS ONE 7:e31406. 2012
    ..We aimed to evaluate this genetic association via a case-control study and meta-analysis...
  26. doi request reprint Reduced serum levels of vasostatin-2, an anti-inflammatory peptide derived from chromogranin A, are associated with the presence and severity of coronary artery disease
    Lin Lu
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui Jin Road II, Shanghai 200025, People s Republic of China
    Eur Heart J 33:2297-306. 2012
    ..We here investigated the endothelial effects of the chromogranin A-derived peptide vasostatin-2 and its relation to coronary artery disease (CAD)...
  27. doi request reprint Serum advanced glycation end-products and receptors as prognostic biomarkers in diabetics undergoing coronary artery stent implantation
    Ying Shen
    Department of Cardiology, Rui Jin Hospital, Medical School of Jiaotong University, Ruijin Hospital, 197 Rui Jin Road II, Shanghai, People s Republic of China
    Can J Cardiol 28:737-43. 2012
    ....
  28. pmc The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is associated with increased risk of coronary artery disease: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    PLoS ONE 7:e53105. 2012
    ..Contradictory results have been reported regarding the association between Pro12Ala polymorphism of PPARγ2 and coronary artery disease (CAD). We sought to estimate the inconsistent results by performing a comprehensive meta-analysis...
  29. doi request reprint Triptolide inhibits rat vascular smooth muscle cell proliferation and cell cycle progression via attenuation of ERK1/2 and Rb phosphorylation
    Rong Tao
    Department of Cardiology, Ruijin Hospital, Jiao Tong University, Shanghai 200025, China
    Exp Mol Pathol 90:137-42. 2011
    ..In the present study, we investigated effects of triptolide on in-stent restenosis in vivo and in vitro, and study the biological mechanism of this drug...
  30. ncbi request reprint Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese
    Yan Liu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, PR China
    Tohoku J Exp Med 224:119-25. 2011
    ..In conclusion, we show a protective effect of the haplotype G-C-T-C on the occurrence of CAD, suggesting the involvement of LTA in CAD pathogenesis...
  31. pmc Clinical utility of the ratio between circulating fibrinogen and fibrin (ogen) degradation products for evaluating coronary artery disease in type 2 diabetic patients
    Wei Xin Xiong
    Department of Cardiology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 128:727-32. 2015
    ..We investigated whether and to what extent the ratio between circulating fibrinogen (Fg) and its degradation products (FDP) reflects the severity of coronary artery disease (CAD) in type 2 diabetic patients...
  32. pmc Data on the value of elevated circulating mimecan levels for detecting poor coronary collateralization in patients with stable angina and chronic total occlusion
    Ying Shen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Data Brief 9:585-588. 2016
    ....
  33. doi request reprint Diabetes-Invoked High-Density Lipoprotein and Its Association With Coronary Artery Disease in Patients With Type 2 Diabetes Mellitus
    Jia Teng Sun
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Am J Cardiol 118:1674-1679. 2016
    ..Furthermore, the proinflammatory ability of HDL was a significant predictor for the presence of CAD in patients with DM...
  34. doi request reprint Association of serum mimecan with angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion
    Ying Shen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    Atherosclerosis 252:75-81. 2016
    ..We investigated whether and to what extent serum mimecan reflects angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion...
  35. pmc Serum Cystatin C Reflects Angiographic Coronary Collateralization in Stable Coronary Artery Disease Patients with Chronic Total Occlusion
    Ying Shen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People s Republic of China
    PLoS ONE 10:e0137253. 2015
    ..We investigated whether and to what extent cystatin C was associated with angiographic coronary collateralization in patients with stable coronary artery disease and chronic total occlusion...
  36. pmc The Effect of Renin-Angiotensin-Aldosterone System Blockade Medications on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography: A Meta-Analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People s Republic of China
    PLoS ONE 10:e0129747. 2015
    ..We evaluated the association between the administration of ACEI/ARBs and CIN, as well as the effect of ACEI/ARBs on post-procedural changes in renal function index, in patients undergoing CAG...
  37. pmc Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People s Republic of China
    BMC Med Genet 15:118. 2014
    ..To increase precision and to minimize residual confounding, we exploited the cholesteryl ester transfer protein (CETP)-TaqIB polymorphism as an instrument based on Mendelian randomization...
  38. pmc Heterogeneous effect of two selectin gene polymorphisms on coronary artery disease risk: a meta-analysis
    Zhijun Wu
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    PLoS ONE 9:e88152. 2014
    ..The E-selectin Ser128Arg polymorphism and the P-selectin Thr715Pro polymorphism have been investigated widely but with inconsistent results. We performed a comprehensive meta-analysis to shed light on this issue...
  39. doi request reprint Receptor mediated elevation in FABP4 levels by advanced glycation end products induces cholesterol and triacylglycerol accumulation in THP-1 macrophages
    Xiao Qun Wang
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, 197 Rui Jin Road II, Shanghai 200025, People s Republic of China
    Lipids 46:479-86. 2011
    ....
  40. doi request reprint Beneficial effects of intracoronary tirofiban bolus administration following upstream intravenous treatment in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: the ICT-AMI study
    Tian qi Zhu
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, People s Republic of China
    Int J Cardiol 165:437-43. 2013
    ....
  41. doi request reprint Increased serum YKL-40 and C-reactive protein levels are associated with angiographic lesion progression in patients with coronary artery disease
    Jian Lei Zheng
    Department of Cardiology, Rui Jin Hospital, Jiaotong University School of Medicine, Shanghai 200025, PR China
    Atherosclerosis 210:590-5. 2010
    ..This study aimed to assess the possible association between YKL-40 and coronary lesion progression in CAD patients...
  42. ncbi request reprint A uremic solute, P-cresol, inhibits the proliferation of endothelial progenitor cells via the p38 pathway
    Yuan Ying
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Circ J 75:2252-9. 2011
    ..Endothelial dysfunction is a consistent finding in uremic patients. Whether the uremic solutes, p-cresol and indoxyl sulfate, affect the cellular function of endothelial progenitor cells (EPCs) was tested...
  43. pmc Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells
    Ke Yang
    Department of Cardiology, Ruijin Hospital, Jiaotong University School of Medicine, Shanghai, P R China
    Cardiovasc Diabetol 9:66. 2010
    ..MSCs have a potential role in cell replacement therapy in acute myocardial infarction and ischemic cardiomyopathy. However, mechanisms of AGEs on MSCs are still not unveiled...
  44. doi request reprint Polymorphisms of MMP-3 and TIMP-4 genes affect angiographic coronary plaque progression in non-diabetic and type 2 diabetic patients
    Qiu Jing Chen
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, PR China
    Clin Chim Acta 405:97-103. 2009
    ..This study examined whether genetic variants of matrix metallopeptidases (MMPs) and their tissue inhibitors (TIMPs) were associated with angiographic coronary plaque progression (PP) in type 2 diabetic and non-diabetic patients...
  45. pmc Cyanate-Impaired Angiogenesis: Association With Poor Coronary Collateral Growth in Patients With Stable Angina and Chronic Total Occlusion
    Jia Teng Sun
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Am Heart Assoc 5:. 2016
    ..Cyanate has recently gained attention for its role in the pathogenesis of vascular injury. Nonetheless, the effect of cyanate on angiogenesis remains unclear...
  46. pmc IL-34 is associated with the presence and severity of renal dysfunction and coronary artery disease in patients with heart failure
    Qin Fan
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P R China
    Sci Rep 6:39324. 2016
    ..In conclusion, elevated serum IL-34 levels were demonstrated to be independently associated with renal insufficiency and CAD in patients with CHF, regardless of the systolic function...
  47. doi request reprint Elevation of ADAM10, ADAM17, MMP-2 and MMP-9 expression with media degeneration features CaCl2-induced thoracic aortic aneurysm in a rat model
    Liang Geng
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, People s Republic of China
    Exp Mol Pathol 89:72-81. 2010
    ....
  48. pmc Low serum calcium is associated with left ventricular systolic dysfunction in a Chinese population with coronary artery disease
    Yong Wang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Sci Rep 6:22283. 2016
    ..Serum calcium levels are significantly decreased following AMI. Low serum calcium is independently correlated with left ventricular systolic dysfunction in CAD patients with and without AMI. ..
  49. doi request reprint Increased carbamylation level of HDL in end-stage renal disease: carbamylated-HDL attenuated endothelial cell function
    Jia Teng Sun
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Am J Physiol Renal Physiol 310:F511-7. 2016
    ..In conclusion, the present study identified a significantly increased carbamylation level of HDL in ESRD. Furthermore, C-HDL inhibited endothelial cell repair functions. ..
  50. doi request reprint Increased serum high-mobility group box-1 and cleaved receptor for advanced glycation endproducts levels and decreased endogenous secretory receptor for advanced glycation endproducts levels in diabetic and non-diabetic patients with heart failure
    Ling Jie Wang
    Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui Jin Road II, Shanghai 200025, People s Republic of China
    Eur J Heart Fail 13:440-9. 2011
    ..An HMGB1-RAGE interaction has been implicated in cardiac dysfunction. We assessed the association of HMGB1 and RAGE isoforms with heart failure (HF) in diabetic and non-diabetic patients...
  51. doi request reprint [Association between the -1031T/C polymorphism in tumor necrosis factor-alpha gene and unstable angina]
    Yan Liu
    Department of Cardiology, Ruijin Hospital, Institute of Cardiology, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, PR China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26:571-4. 2009
    ..To investigate the association between the -1031T/C polymorphism in the promoter of tumor necrosis factor-alpha (TNF- alpha) gene and unstable angina in Chinese Han population...
  52. ncbi request reprint Glycation of high-density lipoprotein in type 2 diabetes mellitus
    Jia Teng Sun
    Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Chin Med J (Engl) 126:4162-5. 2013
    ..To evaluate whether glycation of high-density lipoprotein (HDL) increases cardiovascular risk in patients with type 2 diabetes mellitus by altering its anti-atherogenic property...
  53. doi request reprint FTY720 attenuates hypoxia-reoxygenation-induced apoptosis in cardiomyocytes
    Min Wang
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, China
    Exp Mol Pathol 97:218-24. 2014
    ..This effect is achieved by inhibiting caspase-3 expression, inflammatory cytokine levels and activating AKT and ERK1/2 signaling pathways. The prosurvival signal activation is dependent on S1P1, 3 subtype receptors and Gi protein. ..
  54. doi request reprint Serial assessment of left ventricular remodeling and function by echo-tissue Doppler imaging after myocardial infarction in streptozotocin-induced diabetic swine
    Wen Ruan
    Department of Cardiology, Rui Jin Hospital, Jiao Tong University School of Medicine, Shanghai, People s Republic of China
    J Am Soc Echocardiogr 22:530-6. 2009
    ..The aim of this study was to determine the value of Doppler tissue imaging (DTI) in detecting serial changes in left ventricular (LV) geometry and function after myocardial infarction (MI) in diabetic swine...