Hui Zhao

Summary

Affiliation: Institute of Soil and Water Conservation
Country: China

Publications

  1. ncbi request reprint Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells
    Hui Zhong Zhang
    Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi an, China
    Cancer Biol Ther 5:1457-61. 2006
  2. ncbi request reprint [Significance of stathmin gene overexpression in osteosarcoma cells]
    Hui Zhong Zhang
    Center of Clinical Research, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, 710038, PR China
    Ai Zheng 23:493-6. 2004
  3. doi request reprint Downregulation of SS18-SSX1 expression by small interfering RNA inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro
    Changliang Peng
    Musculoskeletal Tumor Centre, Peking University People s Hospital, Beijing, China
    Eur J Cancer Prev 17:392-8. 2008
  4. ncbi request reprint [Inhibitory effect of antisense oligodeoxynucleotides targeting HER-2 mRNA on growth of breast cancer: experiment in vivo with mice]
    Jun Zhong Sun
    No 304 Clinical Department, General Hospital of Chinese People s Liberation Army, Beijing 100039, China
    Zhonghua Yi Xue Za Zhi 86:540-3. 2006
  5. ncbi request reprint Early down-regulation of Bcl-xL expression during megakaryocytic differentiation of thrombopoietin-induced CD34+ bone marrow cells in essential thrombocythemia
    Lei Zhang
    State Key Laboratory of Experimental Hematology, National Research Center for Stem Cell Engineering and Technology, Institute of Haematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, PR China
    Haematologica 89:1199-206. 2004
  6. ncbi request reprint Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals
    Hui Zhao
    Stanford University School of Medicine, USA
    Mol Imaging 3:43-54. 2004
  7. ncbi request reprint Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells
    Hui Zhao
    Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
    Int J Cancer 109:65-70. 2004
  8. pmc Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
    Hui Zhao
    Department of Cell Biology and Physiology, Howard Hughes Medical Institute, Washington University School of Medicine, Box 8228, 660 South Euclid Avenue, St Louis, MO 63110 1093, USA
    Proc Natl Acad Sci U S A 99:14795-800. 2002
  9. doi request reprint Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice
    Juan Li Lu
    Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
    Eur J Pharm Biopharm 69:899-907. 2008
  10. ncbi request reprint SBD.4 stimulates regenerative processes in vitro, and wound healing in genetically diabetic mice and in human skin/severe-combined immunodeficiency mouse chimera
    Hui Zhao
    Sunny BioDiscovery, Santa Clara, California 95050, USA
    Wound Repair Regen 14:593-601. 2006

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells
    Hui Zhong Zhang
    Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi an, China
    Cancer Biol Ther 5:1457-61. 2006
    ..Our study indicates that survivin gene promoter-driven stathmin siRNA expression vector may have potential use in tumor gene therapy with targeted tumor gene silencing effect...
  2. ncbi request reprint [Significance of stathmin gene overexpression in osteosarcoma cells]
    Hui Zhong Zhang
    Center of Clinical Research, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, 710038, PR China
    Ai Zheng 23:493-6. 2004
    ....
  3. doi request reprint Downregulation of SS18-SSX1 expression by small interfering RNA inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro
    Changliang Peng
    Musculoskeletal Tumor Centre, Peking University People s Hospital, Beijing, China
    Eur J Cancer Prev 17:392-8. 2008
    ..Our results demonstrate that siRNA targeting of SS18-SSX1 may have therapeutic potential in the treatment of synovial sarcomas...
  4. ncbi request reprint [Inhibitory effect of antisense oligodeoxynucleotides targeting HER-2 mRNA on growth of breast cancer: experiment in vivo with mice]
    Jun Zhong Sun
    No 304 Clinical Department, General Hospital of Chinese People s Liberation Army, Beijing 100039, China
    Zhonghua Yi Xue Za Zhi 86:540-3. 2006
    ..To investigate the inhibitory effect of antisense oligodeoxynucleotides targeting HER-2 mRNA on growth of breast cancer...
  5. ncbi request reprint Early down-regulation of Bcl-xL expression during megakaryocytic differentiation of thrombopoietin-induced CD34+ bone marrow cells in essential thrombocythemia
    Lei Zhang
    State Key Laboratory of Experimental Hematology, National Research Center for Stem Cell Engineering and Technology, Institute of Haematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, PR China
    Haematologica 89:1199-206. 2004
    ..In this study the expression of Bcl-xL was evaluated during megakaryocytic differentiation in ET patients...
  6. ncbi request reprint Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals
    Hui Zhao
    Stanford University School of Medicine, USA
    Mol Imaging 3:43-54. 2004
    ....
  7. ncbi request reprint Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells
    Hui Zhao
    Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
    Int J Cancer 109:65-70. 2004
    ....
  8. pmc Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
    Hui Zhao
    Department of Cell Biology and Physiology, Howard Hughes Medical Institute, Washington University School of Medicine, Box 8228, 660 South Euclid Avenue, St Louis, MO 63110 1093, USA
    Proc Natl Acad Sci U S A 99:14795-800. 2002
    ..These findings indicate that Chk1 directly phosphorylates Cdc25A during an unperturbed cell cycle, and that phosphorylation of Cdc25A by Chk1 is required for cells to delay cell cycle progression in response to double-strand DNA breaks...
  9. doi request reprint Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice
    Juan Li Lu
    Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
    Eur J Pharm Biopharm 69:899-907. 2008
    ..9-NC SMEDDS represents a novel 9-NC therapy for cancer patients...
  10. ncbi request reprint SBD.4 stimulates regenerative processes in vitro, and wound healing in genetically diabetic mice and in human skin/severe-combined immunodeficiency mouse chimera
    Hui Zhao
    Sunny BioDiscovery, Santa Clara, California 95050, USA
    Wound Repair Regen 14:593-601. 2006
    ..4a...
  11. ncbi request reprint Orthopoxvirus pan-genomic DNA assay
    Yu Li
    Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    J Virol Methods 141:154-65. 2007
    ....
  12. ncbi request reprint Abnormality of CD4(+)CD25(+) regulatory T cells in idiopathic thrombocytopenic purpura
    Bin Liu
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
    Eur J Haematol 78:139-43. 2007
    ..The aim of this study was to explore the profile and function of CD4(+)CD25(+) regulatory T cells (Treg cells) in idiopathic thrombocytopenic purpura (ITP) patients...
  13. pmc WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation
    Kosuke Tanegashima
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    EMBO J 27:606-17. 2008
    ..These results indicate that WGEF is a component of the Wnt-PCP pathway that connects Dishevelled to Rho activation...
  14. doi request reprint Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)
    Zhi Bo Han
    The State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Peking Union of Medical College, Tianjin 300020, China
    Carcinogenesis 29:1853-61. 2008
    ..Hypoxia and epidermal growth factor receptor signal coexisted in the tumor microenvironment and might promote angiogenesis through HIF-1 alpha-mediated upregulation of SCF and other angiogenic factors...
  15. doi request reprint Effect of SBD.4A--a defined multicomponent preparation of Angelica sinensis--in periodontal regeneration models
    Hui Zhao
    Sunny BioDiscovery 2070A Walsh Ave Santa Clara, CA 95050 and 722 East Main St Santa Paula, CA 93060, USA
    Phytother Res 22:923-8. 2008
    ..Together, these results indicate the beneficial effect of SBD.4 on periodontal ligament and bone regeneration making the case for further development of this botanical growth factor...
  16. pmc Functional variants of the NEIL1 and NEIL2 genes and risk and progression of squamous cell carcinoma of the oral cavity and oropharynx
    Xiadong Zhai
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 14:4345-52. 2008
    ..To date, only one reported study has investigated the association between NEIL1 and NEIL2 polymorphisms and cancer risk...
  17. doi request reprint Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura
    Jie Tao
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, People s Republic of China
    J Clin Immunol 28:432-9. 2008
    ..The aim of this study is to explore if DNA methylation plays a role in the pathogenesis of idiopathic thrombocytopenic purpura (ITP)...
  18. pmc Dendritic cell-Ewing's sarcoma cell hybrids enhance antitumor immunity
    Wei Guo
    Musculoskeletal Tumor Center, Peking University People s Hospital, 11 South Xizhimen Street, Beijing 100044, People s Republic of China
    Clin Orthop Relat Res 466:2176-83. 2008
    ..However, the hybrids most inhibited the subcutaneous tumor growth in SCID mice compared with dendritic cells pulsed with other loading methods. The data suggest A673 cells respond to dendritic cell-based immunotherapy...
  19. ncbi request reprint Combined chemotherapy of hydroxycampothecin with oxaliplatin as an adjuvant treatment for human colorectal cancer
    Yang Yao
    Department of Medical Oncology, Sixth People s Hospital, Shanghai Jiaotong University, China
    Tohoku J Exp Med 215:267-78. 2008
    ..Taken together, the present study indicates that the combined chemotherapy of HCPT with L-OHP could become a new adjuvant treatment for CRC...
  20. pmc Human neutralizing Fab molecules against severe acute respiratory syndrome coronavirus generated by phage display
    Xiaoping Kang
    State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
    Clin Vaccine Immunol 13:953-7. 2006
    ..These data showed that the number of virus copies was significantly reduced in the M1A-treated group, suggesting an important role for M1A in passive immunoprophylaxis against the SARS virus...
  21. ncbi request reprint Murine model of gastrointestinal ischemia associated with complement-dependent injury
    Hui Zhao
    Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Appl Physiol 93:338-45. 2002
    ..This model will be well suited to investigate the role of complement-mediated tissue injury and gene expression after gastrointestinal I/R...
  22. ncbi request reprint Nitric oxide induces hyperpolarization by opening ATP-sensitive K(+) channels in guinea pig spiral modiolar artery
    Jun qiang Si
    Oregon Hearing Research Center, Oregon Health and Science University, Portland, OR 97201, USA
    Hear Res 171:167-176. 2002
    ..It is concluded that NO hyperpolarizes the SMA primarily by activating K(ATP) channels in both muscle and endothelial cells...
  23. ncbi request reprint Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II
    Justin M Cole
    Department of Pathology, Emory University, Atlanta, GA 30322, USA
    Hypertension 41:313-21. 2003
    ..The ACE 1/3 mice demonstrate the plasticity of the RAS and show that significant compensation is required to maintain normal, basal blood pressure in a mouse with an impaired local vascular and renal RAS...
  24. ncbi request reprint Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases
    Hui Zhao
    Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    FASEB J 17:723-4. 2003
    ..These data suggest that alterations in GCS expression following brief periods of oxidative stress in human endothelial cells lead to increased caspase activity...
  25. ncbi request reprint Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
    Dmitry V Bulavin
    Gene Response Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Nat Cell Biol 5:545-51. 2003
    ..We propose that this pathway ensures that Cdc2 remains active once mitosis is initiated and is a key control mechanism for maintaining the proper order of cell-cycle transitions...
  26. ncbi request reprint A genome sequence of novel SARS-CoV isolates: the genotype, GD-Ins29, leads to a hypothesis of viral transmission in South China
    E de Qin
    Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China
    Genomics Proteomics Bioinformatics 1:101-7. 2003
    ..It provides a new avenue for the exploration of the virus-host interaction in viral evolution, host pathogenesis, and vaccine development...
  27. pmc AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion
    James C Mulloy
    Division of Experimental Hematology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 102:4016-21. 2005
    ....
  28. ncbi request reprint Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice
    Yulin Liao
    Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Cardiovasc Res 70:107-16. 2006
    ..This study was designed to determine whether impaired glucose tolerance develops during the progression of cardiac hypertrophy and heart failure, and whether tight glycemic control could reduce the severity of heart failure...
  29. ncbi request reprint A transgenic rice seed accumulating an anti-hypertensive peptide reduces the blood pressure of spontaneously hypertensive rats
    Lijun Yang
    Transgenic Crop Research and Development Center, National Institute of Agrobiological Sciences NIAS, Tsukuba, Ibaraki 305 8602, Japan
    FEBS Lett 580:3315-20. 2006
    ..These results suggest the possible application of transgenic rice seed as a nutraceutical delivery system and specifically for administration of active peptides in hypertension...
  30. ncbi request reprint Expression of mRNA for multiple serotonin (5-HT) receptor types/subtypes by the peripheral blood mononuclear cells of rhesus macaques
    Gui bo Yang
    State Key Laboratory for Infectious Disease Prevention and Control, People s Republic of China
    J Neuroimmunol 178:24-9. 2006
    ..This provided a basis for further studies on the neuroimmunomodulatory interactions of 5-HT in rhesus macaques...
  31. pmc Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations
    Min Xin Guan
    Division and Program in Human Genetics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Am J Hum Genet 79:291-302. 2006
    ..These findings indicate that the mutated TRMU, acting as a modifier factor, modulates the phenotypic manifestation of the deafness-associated 12S rRNA mutations...
  32. ncbi request reprint [Immediate immunological effect of China-made recombinant hepatitis B vaccine expressed by transgenic Chinese hamster ovary cell line]
    Hongbin Liu
    Hebei Provincial Sanitation and Anti epidemic Station, Baoding, 071000, China
    Zhonghua Yi Xue Za Zhi 82:43-6. 2002
    ..To understand the protective efficacy of China-made recombinant hepatitis B vaccine expressed by transgenic Chinese hamster ovary cell line among newborns...