Y Wang

Summary

Affiliation: Institute of Vertebrate Paleontology and Paleoanthropology
Country: China

Publications

  1. doi request reprint M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
    Eur J Neurol 15:827-30. 2008
  2. ncbi request reprint An ossified Meckel's cartilage in two Cretaceous mammals and origin of the mammalian middle ear
    Y Wang
    Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing, 100044, China
    Science 294:357-61. 2001
  3. doi request reprint Incidence of invasive fungal disease after unmanipulated haploidentical stem cell transplantation was significantly higher than that after HLA-matched sibling transplantation
    Y Sun
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Diseases, Beijing, China
    Clin Microbiol Infect 19:1029-34. 2013
  4. doi request reprint Paroxysmal kinesigenic choreoathetosis: evidence of linkage to the pericentromeric region of chromosome 16 in four Chinese families
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 17:800-7. 2010
  5. doi request reprint Prevention of relapse using granulocyte CSF-primed PBPCs following HLA-mismatched/haploidentical, T-cell-replete hematopoietic SCT in patients with advanced-stage acute leukemia: a retrospective risk-factor analysis
    Y Wang
    Peking University People s Hospital, Institute of Hematology, No 11Xizhimen South Street, Xicheng, Beijing, China
    Bone Marrow Transplant 47:1099-104. 2012
  6. doi request reprint Long-term outcomes of unmanipulated haploidentical HSCT for paediatric patients with acute leukaemia
    D H Liu
    Department of Bone Marrow Transplantation, People s Hospital, Institute of Hematology, Peking University, Beijing, China
    Bone Marrow Transplant 48:1519-24. 2013
  7. doi request reprint Accuracy of genomic prediction for milk production traits in the Chinese Holstein population using a reference population consisting of cows
    X Ding
    Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China
    J Dairy Sci 96:5315-23. 2013
  8. doi request reprint Single-nucleotide polymorphisms in the promoter of the growth hormone-releasing hormone receptor gene are associated with growth and reproduction traits in chickens
    W Liu
    Key Laboratory of Agricultural Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China
    Anim Genet 43:564-9. 2012
  9. doi request reprint Basiliximab for the treatment of steroid-refractory acute graft-versus-host disease after unmanipulated HLA-mismatched/haploidentical hematopoietic stem cell transplantation
    J Z Wang
    Peking University People s Hospital, Institute of Hematology, Beijing, China
    Transplant Proc 43:1928-33. 2011
  10. pmc CTLA-4 polymorphisms and haplotype correlate with survival in ALL after allogeneic stem cell transplantation from related HLA-haplotype-mismatched donor
    X Y Qin
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China
    J Transl Med 14:100. 2016

Collaborators

  • Y Zhang
  • J Wang
  • Jost Jonas
  • M C Marquez
  • C Li
  • H Yang
  • Liang Xu
  • Yong Yang
  • L Zhang
  • X J Huang
  • W Han
  • H Chen
  • X H Zhang
  • K Y Liu
  • F R Wang
  • Y H Chen
  • Y Chen
  • J Li
  • X Wang
  • Z Wang
  • D H Liu
  • X D Mo
  • H Zhang
  • W Zhang
  • J Liu
  • Z Zhang
  • J Zhao
  • T An
  • C H Yan
  • H Wang
  • F Wang
  • S Wang
  • L Yang
  • Y J Chang
  • Y Q Sun
  • Z Li
  • X Li
  • J Duan
  • X Wu
  • M Wu
  • L Liu
  • J Zhang
  • Y Liu
  • D Ma
  • J Chen
  • X Liu
  • L Wang
  • X Y Qin
  • Y Z Qin
  • Y Sun
  • H Jiang
  • Q Wang
  • X Chen
  • M Li
  • X Zhang
  • W Liang
  • Y Yu
  • S Zhang
  • G Wang
  • C Chen
  • Z Y Zhang
  • W Liu
  • H Bai
  • S Yu
  • Q Zhang
  • S Zhu
  • L Jia
  • X Song
  • Q Jiang
  • W Li
  • H Peng
  • K Liu
  • X Xu
  • P Wang
  • X Guo
  • G Chen
  • Y Y Li
  • C Wang
  • J Yang
  • G Guo
  • Y Li
  • D Chen
  • D Lin
  • H Liu
  • R Chen
  • M Fan
  • L Li
  • W Sun
  • X Zhu
  • T Li

Detail Information

Publications143 found, 100 shown here

  1. doi request reprint M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
    Eur J Neurol 15:827-30. 2008
    ..We screened variations in the open-reading frame (ORF) of the PRNP gene and also replicated the association of the M129V polymorphism with TLE in a Han Chinese population...
  2. ncbi request reprint An ossified Meckel's cartilage in two Cretaceous mammals and origin of the mammalian middle ear
    Y Wang
    Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing, 100044, China
    Science 294:357-61. 2001
    ..Modifications of both feeding and hearing apparatuses in early mammals may have led to the development of the definitive mammalian middle ear...
  3. doi request reprint Incidence of invasive fungal disease after unmanipulated haploidentical stem cell transplantation was significantly higher than that after HLA-matched sibling transplantation
    Y Sun
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Diseases, Beijing, China
    Clin Microbiol Infect 19:1029-34. 2013
    ..In conclusion, patients who received unmanipulated haploidentical HSCT had a higher risk of IFD than those patients who received HLA-matched HSCT, but the prognosis of IFD was not associated with the HLA type. ..
  4. doi request reprint Paroxysmal kinesigenic choreoathetosis: evidence of linkage to the pericentromeric region of chromosome 16 in four Chinese families
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 17:800-7. 2010
    ..The pericentromeric region of chromosome 16 has been linked to PKC by several reports. This study was to localize and identify PKC gene in four Chinese PKC families...
  5. doi request reprint Prevention of relapse using granulocyte CSF-primed PBPCs following HLA-mismatched/haploidentical, T-cell-replete hematopoietic SCT in patients with advanced-stage acute leukemia: a retrospective risk-factor analysis
    Y Wang
    Peking University People s Hospital, Institute of Hematology, No 11Xizhimen South Street, Xicheng, Beijing, China
    Bone Marrow Transplant 47:1099-104. 2012
    ..002), AML (P=0.027) and female sex (P=0.023). Our results suggest that use of prophylactic GPBPCI may increase survival of patients with advanced-stage acute leukemia who receive HLA-mismatched/haploidentical HSCT...
  6. doi request reprint Long-term outcomes of unmanipulated haploidentical HSCT for paediatric patients with acute leukaemia
    D H Liu
    Department of Bone Marrow Transplantation, People s Hospital, Institute of Hematology, Peking University, Beijing, China
    Bone Marrow Transplant 48:1519-24. 2013
    ..In MSD group, LFS for ALL and AML in CR1 were 62.5 and 71.7%. Outcomes of the HID HSCT for paediatric patients with acute leukaemia showed benefits that were similar to those of the parallel cohort of MSD HSCT. ..
  7. doi request reprint Accuracy of genomic prediction for milk production traits in the Chinese Holstein population using a reference population consisting of cows
    X Ding
    Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China
    J Dairy Sci 96:5315-23. 2013
    ..13 to 0.30 and 0.23 to 0.33 higher than the accuracies of conventional pedigree index, respectively. The results indicate that, as an alternative, genomic selection using cows in the reference population is feasible...
  8. doi request reprint Single-nucleotide polymorphisms in the promoter of the growth hormone-releasing hormone receptor gene are associated with growth and reproduction traits in chickens
    W Liu
    Key Laboratory of Agricultural Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China
    Anim Genet 43:564-9. 2012
    ..05). These results suggest that the three SNPs in the GHRHR promoter could be used as potential genetic markers to improve the growth and reproductive traits in chickens...
  9. doi request reprint Basiliximab for the treatment of steroid-refractory acute graft-versus-host disease after unmanipulated HLA-mismatched/haploidentical hematopoietic stem cell transplantation
    J Z Wang
    Peking University People s Hospital, Institute of Hematology, Beijing, China
    Transplant Proc 43:1928-33. 2011
    ..We investigated the efficacy and safety of the chimeric Mab, basiliximab, to treat steroid-refractory acute GVHD after unmanipulated mismatched/haploidentical HSCT...
  10. pmc CTLA-4 polymorphisms and haplotype correlate with survival in ALL after allogeneic stem cell transplantation from related HLA-haplotype-mismatched donor
    X Y Qin
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China
    J Transl Med 14:100. 2016
    ..T cell homeostasis is critical to determine the potency of the GVT effect. Recent studies have shown the association of the CTLA-4 polymorphisms with the outcome after HLA-identical sibling allogeneic HSCT...
  11. doi request reprint Late-onset severe pneumonia after allogeneic hematopoietic stem cell transplantation: prognostic factors and treatments
    X D Mo
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China
    Transpl Infect Dis 18:492-503. 2016
    ..In this study, we aimed to evaluate the prognostic factors associated with and treatments for late-onset severe pneumonia (LOSP) in patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT)...
  12. ncbi request reprint Chemotherapy influence EGFR mutation status for Chinese patients with regionally advanced non-small cell lung cancer
    J Wang
    Peking University Cancer Hospital, Peking University School of Oncology, Beijing Cancer Hospital, Beijing, China Department of Thoracic Surgery, Beijing, China Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, China Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Beijing, China
    J Clin Oncol 29:7031. 2011
    ..However, it remains unclear whether there is a need to detect EGFR mutations before using second-line EGFR-TKI therapy. The key to answer this question is to identify whether chemotherapy may change EGFR mutation status...
  13. doi request reprint Patients with refractory cytomegalovirus (CMV) infection following allogeneic haematopoietic stem cell transplantation are at high risk for CMV disease and non-relapse mortality
    J Liu
    Peking University People s Hospital, Institute of Haematology, Beijing Key Laboratory of HSCT, Beijing, China
    Clin Microbiol Infect 21:1121.e9-15. 2015
    ..001) and acute graft-versus-host disease (HR 1.905, 95% CI 1.352-2.686, p <0.001). We conclude that patients with refractory CMV infection during the early stage after allo-HSCT are at high risk for both CMV disease and NRM. ..
  14. doi request reprint Chronic GVHD induced GVL effect after unmanipulated haploidentical hematopoietic SCT for AML and myelodysplastic syndrome
    X D Mo
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China
    Bone Marrow Transplant 50:127-33. 2015
    ....
  15. doi request reprint Pivotal role of augmented αB-crystallin in tumor development induced by deficient TSC1/2 complex
    F Wang
    State Key Laboratory of Medical Molecular Biology, Department of Physiology and Pathophysiology, Institute of Basic Medical Sciences and School of Basic Medicine, Graduate School of Peking Union Medical College, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
    Oncogene 33:4352-8. 2014
    ..Therefore, enhanced αB-crystallin has an essential role in TSC1/2 complex deficiency-mediated tumorigenesis, and inhibition of αB-crystallin may complement the current therapy for TSC. ..
  16. doi request reprint COMT rs4680 Met is not always the 'smart allele': Val allele is associated with better working memory and larger hippocampal volume in healthy Chinese
    Y Wang
    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Genes Brain Behav 12:323-9. 2013
    ..110, t = -2.315, P = 0.021). These results add to the growing literature on differentiated effects of COMT rs4680 polymorphism on WM across populations and offer a brain structural mechanism for such population-specific genetic effects...
  17. pmc mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development
    H Peng
    Department of Physiology and Pathophysiology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Oncogene 32:4702-11. 2013
    ..In contrast, SOCE agonists should attenuate mTOR inhibitors-mediated AKT reactivation and consequently potentiate their efficacy in the treatment of the patients with TSC. ..
  18. doi request reprint The incidence and risk factors of invasive fungal infection after haploidentical haematopoietic stem cell transplantation without in vitro T-cell depletion
    Y Q Sun
    Peking University People s Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation for the Treatment of Haematological Diseases, Beijing, China
    Clin Microbiol Infect 18:997-1003. 2012
    ..48%, 7.86%, 29.6% and 23.1%, respectively. In conclusion, IFI is an important complication following haploidentical HSCT without in vitro T-cell depletion...
  19. doi request reprint Association study of functional polymorphisms in serotonin transporter gene with temporal lobe epilepsy in Han Chinese population
    J Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 19:351-3. 2012
    ..We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gene expression or function, and risk for TLE...
  20. pmc A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis
    D Ma
    Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Thromb Haemost 105:1032-45. 2011
    ..The RGD motif in the unique sequence of Tablysin-15 represents a novel template for studying the structure-function relationship of the disintegrin family of inhibitors...
  21. ncbi request reprint Retreatment after the failure of initial epidermal growth factor receptor inhibitor in non-small cell lung cancer
    T An
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Beijing, China Peking University Cancer Hospital, Peking University School of Oncology, Beijing Cancer Hospital, Beijing, China Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, China
    J Clin Oncol 29:e18048. 2011
    ..More recently, EGFR-TKI also shows antitumor activity in first-line therapy. However, patients with advanced NSCLC have few treatment options available if they are refractory to EGFR-TKI...
  22. doi request reprint Malignant pleural effusion cell blocks are substitutes for tissue in EML4-ALK rearrangement detection in patients with advanced non-small-cell lung cancer
    J Zhong
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Department of Thoracic Medical Oncology I, Peking University Cancer Hospital and Institute, Beijing, China
    Cytopathology 27:433-443. 2016
    ....
  23. doi request reprint Comparable post-relapse outcomes between haploidentical and matched related donor allogeneic stem cell transplantation
    Y R Ma
    Department of Hematology, Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant . 2016
    ..Bone Marrow Transplantation advance online publication, 31 October 2016; doi:10.1038/bmt.2016.283...
  24. ncbi request reprint Effect of wnt aberrant methylation and epidermal growth factor receptor pathway mutation on responsiveness of non-small cell lung cancer to gefitinib and erlotinib
    J Zhu
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Beijing, China Peking University Cancer Hospital, Peking University School of Oncology, Beijing Cancer Hospital, Beijing, China Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, China
    J Clin Oncol 29:e18011. 2011
    ..Little is known about the synchronous effect on EGFR tyrosine-kinase inhibitors (EGFR-TKIs) treatment in NSCLC...
  25. doi request reprint Detection of functional polymorphisms influencing the promoter activity of the SAA2 gene and their association with milk production traits in Chinese Holstein cows
    S Yang
    College of Animal Science and Technology, Key Laboratory of Animal Genetics and Breeding of Ministry of Agriculture, National Engineering Laboratory of Animal Breeding, China Agricultural University, Beijing, 100193, China
    Anim Genet 46:591-8. 2015
    ..Overall, the findings presented here provide the first evidence for associations of the SAA2 gene with milk fat and protein traits, which appears to be a key candidate for milk production traits in dairy cattle. ..
  26. doi request reprint Detection of human cytomegalovirus (CMV) DNA in feces has limited value in predicting CMV enteritis in patients with intestinal graft-versus-host disease after allogeneic stem cell transplantation
    Y Q Sun
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Diseases, Beijing, China
    Transpl Infect Dis 17:655-61. 2015
    ..We aimed to evaluate the sensitivity and specificity of the detection of CMV DNA in feces for predicting CMV enteritis...
  27. doi request reprint Allogeneic hematopoietic SCT in combination with tyrosine kinase inhibitor treatment compared with TKI treatment alone in CML blast crisis
    H Jiang
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 49:1146-54. 2014
    ..Allo-HSCT with individualized intervention after TKI therapy is superior to TKI alone for CML-BC...
  28. doi request reprint Umbilical cord blood transplantation and unmanipulated haploidentical hematopoietic SCT for pediatric hematologic malignances
    X D Mo
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China
    Bone Marrow Transplant 49:1070-5. 2014
    ..044). The relapse- and disease-free survival rates did not differ significantly between the groups. Our results showed that compared with UCBT, unmanipulated haplo-HSCT can improve the outcomes of children with hematologic malignances...
  29. ncbi request reprint Gestational hypertension risk evaluation based on epidemiological, biochemical, and hemodynamic factors
    L Yang
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    Clin Exp Obstet Gynecol 40:61-5. 2013
    ..Gestational hypertension (GH) is a serious health hazard for pregnant women and fetuses. The incidence of GH involves many epidemiological, biochemical, and hemodynamic factors...
  30. doi request reprint c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3
    X Li
    Beijing Institute of Biotechnology, Beijing, China
    Cell Death Differ 17:1277-87. 2010
    ..As tumors frequently overexpress Gal3, a c-Abl/Arg-specific inhibitor may potentially be applied along with other antitumor drugs to target the lysosomal degradation of Gal3 in tumor therapy...
  31. doi request reprint C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer
    Y Shi
    Sino German Laboratory for Molecular Medicine, Key Laboratory for Clinical Cardiovascular Genetics, Ministry of Education, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
    Oncogene 30:4107-17. 2011
    ..73 (95% confidence interval: 1.33-2.25), P=4.6 × 10(-5)). These data indicated that C10ORF97 is a tumor suppressor of NSCLC progression and C10ORF97-SNP216 may serve as a predictor of NSCLC...
  32. ncbi request reprint An evaluation of phosphorylated EGFR expression in predicting outcome of EGFR-TKI therapy for the advanced NSCLC patients with EGFR wild type
    F Wang
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Beijing, China Peking University Cancer Hospital, Peking University School of Oncology, Beijing Cancer Hospital, Beijing, China Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, China
    J Clin Oncol 29:7532. 2011
    ..Here,we hypothesize that the activation (phosphorylation) of EGFR could be a potential predictive biomarkers to EGFR-TKI treatment among patients in absence of EGFR mutations...
  33. doi request reprint Efficacy and Safety of Bromocriptine-QR in Type 2 Diabetes: A Systematic Review and Meta-Analysis
    W Liang
    Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China
    Horm Metab Res 47:805-12. 2015
    ..Neither hypoglycemia nor other metabolic changes occur with this drug. More data for long-term efficacy and safety are needed for further observation...
  34. doi request reprint Presence of CD34(+)CD38(-)CD58(-) leukemia-propagating cells at diagnosis identifies patients at high risk of relapse with Ph chromosome-positive ALL after allo-hematopoietic SCT
    Y Kong
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 50:348-53. 2015
    ..Our data suggest that presence of CD34(+)CD38(-)CD58(-) LPCs at diagnosis allows rapid identification of high-risk patients for relapse after allo-HSCT. ..
  35. doi request reprint Development and characterization of new microsatellites for walnut (Juglans regia)
    Z Y Zhang
    National Engineering Laboratory for Tree Breeding of the National Development and Reform Commission, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, China
    Genet Mol Res 12:4723-34. 2013
    ..regia, J. nigra, C. cathayensis, Carya dabieshanensis, and A. sinensis. Thirteen highly polymorphic EST-SSRs were further used for genetic analyses in these above five species...
  36. doi request reprint HLA-haploidentical hematopoietic SCT from collateral related donors without in vitro T-cell depletion for hematological malignancies
    Y Y Zhang
    Beijing Key Laboratory, Institute of Hematology, Peking University People s Hospital, Beijing, China
    Bone Marrow Transplant 49:496-501. 2014
    ..4% (P=0.103), respectively. This study shows that haploidentical HSCT from CRDs can provide a safe and effective treatment for patients with hematological malignancies. CRDs could be an alternative when there was no suitable IRDs. ..
  37. doi request reprint Characterization of antimicrobial resistance of Pseudomonas aeruginosa isolated from canine infections
    D Lin
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 113:16-23. 2012
    ..To determine the prevalence of Pseudomonas aeruginosa among dogs with suspected soft tissue infections and to characterize these isolates...
  38. doi request reprint Associations of IL-23R polymorphisms with ankylosing spondylitis in East Asian population: a new case-control study and a meta-analysis
    C Chen
    Department of Spinal and Neural Functional Reconstruction, China Rehabilitation Research Center, School ofRehabilitation Medicine, Capital Medical University, Beijing, China
    Int J Immunogenet 39:126-30. 2012
    ..In conclusion, we found no evidence for association between IL-23R and AS in East Asian population. Major attention should be paid to other genes belonged to IL-23 signalling pathway network in the future...
  39. doi request reprint A clinical case-control study on the association between mannose-binding lectin and susceptibility to HIV-1 infection among northern Han Chinese population
    A Sheng
    School of Public Health and Family Medicine, Capital Medical University, Beijing, China
    Int J Immunogenet 37:445-54. 2010
    ..The individuals with B variant, low serum MBL concentration and low MBL complex activity are more susceptible to HIV-1 infection...
  40. ncbi request reprint Prevalence of diabetes mellitus in China
    L Xu
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Exp Clin Endocrinol Diabetes 116:69-70. 2008
    ..To investigate the prevalence of diabetes mellitus in China...
  41. doi request reprint The cancer/testis antigen MAGEC2 promotes amoeboid invasion of tumor cells by enhancing STAT3 signaling
    X Song
    Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
    Oncogene . 2016
    ..Thus, MAGEC2 may represent a new antitumor metastasis target for treatment of cancer.Oncogene advance online publication, 24 October 2016; doi:10.1038/onc.2016.314...
  42. doi request reprint The nature of anhedonia and avolition in patients with first-episode schizophrenia
    S S Y Lui
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, People s Republic of China
    Psychol Med 46:437-47. 2016
    ..This study aimed to examine avolition and anhedonia in patients with first-episode schizophrenia and clarify the role of working memory in emotion-behaviour coupling...
  43. doi request reprint Quantitative chimerism: an independent acute leukemia prognosis indicator following allogeneic hematopoietic SCT
    X Y Qin
    1 Peking University People s Hospital, Peking University Institute of Hematology, Beijing, China 2 Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 49:1269-77. 2014
    ..5%) than those (n=9) who did not (100%; P=0.001). Thus, quantitative chimerism is an independent prognostic factor that predicts clinical outcomes after HSCT and provides a guide for suitable interventions. ..
  44. doi request reprint Influence of two different doses of antithymocyte globulin in patients with standard-risk disease following haploidentical transplantation: a randomized trial
    Y Wang
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 49:426-33. 2014
    ..88). In conclusion, although 6 mg/kg ATG applied in haploidentical transplantation decreased the risk of EBV reactivation compared with 10 mg/kg ATG, this treatment exposes patients to a higher risk for severe acute GVHD. ..
  45. doi request reprint Health-related quality of life of patients with newly diagnosed chronic myeloid leukemia treated with allogeneic hematopoietic SCT versus imatinib
    X D Mo
    Peking University People s Hospital and Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 49:576-80. 2014
    ..Imatinib therapy was also an adverse factor affecting the MCS (odds ratio=1.7, P=0.032). Thus, long-term CML-CP1 survivors receiving ISD HSCT can attain desirable HRQOL comparable to or better than that of patients receiving imatinib...
  46. doi request reprint Efficacy and safety of short-term administration of recombinant human atrial natriuretic peptide (rhANP) for congestive heart failure: a phase II, multicentre randomized controlled dose-finding study
    P Wang
    State Key Laboratory of Cardiovascular Diseases, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Clin Pharm Ther 38:388-93. 2013
    ..This study was designed to assess the efficacy and safety of short-term infusion of recombinant human atrial natriuretic peptide (rhANP) in CHF patients...
  47. ncbi request reprint Neuregulin-1 protects against doxorubicin-induced apoptosis in cardiomyocytes through an Akt-dependent pathway
    T An
    Heart Failure Center, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Physiol Res 62:379-85. 2013
    ..RhNRG-1 is a novel therapeutic drug which may be effective in preventing further damage from occurring in DOX-induced damaged myocardium. ..
  48. doi request reprint Conservation genetics of Annamocarya sinensis (Dode) Leroy, an endangered endemic species
    Z Y Zhang
    National Engineering Laboratory for Tree Breeding of the National Development and Reform Commission, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, China
    Genet Mol Res 12:3965-74. 2013
    ..The protection strategy should aim to protect as many populations as possible. Promoting sexual reproduction among various genotypes and establishing an outcrossing program are advisable for A. sinensis. ..
  49. doi request reprint Prevalence and antimicrobial resistance of Enterococcus species of food animal origin from Beijing and Shandong Province, China
    Y Liu
    Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 114:555-63. 2013
    ..To evaluate the prevalence and antimicrobial resistance of Enterococcus species from chickens and pigs in Beijing and Shandong Province, China...
  50. doi request reprint Dissemination and characterization of NDM-1-producing Acinetobacter pittii in an intensive care unit in China
    J Yang
    Department of Microbiology, Chinese PLA General Hospital, Beijing, China
    Clin Microbiol Infect 18:E506-13. 2012
    ..pittii isolate. Thus, we present the first report on the transmission and characterization of NDM-1-producing A. pittii in an ICU in China as well as a novel bla(NDM-1) gene-bearing plasmid...
  51. pmc The correlation between T helper type 17 cells and clinical characters in Chinese paediatric patients with chronic hepatitis B
    S Zhu
    Paediatric Liver Disease Therapy and Research Center, 302 Hospital, Beijing, China
    Clin Exp Immunol 171:307-12. 2013
    ..Peripheral Th17 cell frequency is associated closely with inflammation activity of liver tissues in paediatric patients with CHB...
  52. doi request reprint Emergence of resistance to fluoroquinolones and third-generation cephalosporins in Shigella flexneri subserotype 1c isolates from China
    S Qiu
    Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China
    Clin Microbiol Infect 18:E95-8. 2012
    ..Overall, the seven isolates showed reduced susceptibility to ciprofloxacin; one isolate was ciprofloxacin resistant, whilst another developed resistance to ciprofloxacin, norfloxacin, cefotaxime and ceftriaxone...
  53. doi request reprint Efficacy and safety of changing from cyclosporine C0 to C2 monitoring in stable recipients following renal transplantation: a prospective cohort study
    Y Zhang
    Urology Department, Beijing Chao Yang Hospital, Capital Medical University, Beijing, China
    Transplant Proc 43:3697-701. 2011
    ..One must be cautious to change from monitoring C0 to C2 in stable recipients following renal transplantation...
  54. ncbi request reprint Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women
    X Fan
    Hypertension Division, Department of Cardiology, Ministry of Education and Sino German Laboratory for Molecular Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Clin Pharmacol Ther 82:187-96. 2007
    ..3 mm Hg lower in ACE2 T allele carriers than in CC genotype carriers (P=0.019) in women. We conclude that the ACE2 T allele confers a high risk for hypertension and reduced antihypertensive response to ACE inhibitors...
  55. pmc Colitogenic role of tumour necrosis factor (TNF) receptors in trinitrobenzene sulphonic acid colitis: TNF-R1 ablation does not affect systemic inflammatory response
    Y Yang
    Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, China
    Clin Exp Immunol 165:372-82. 2011
    ..These findings suggest that either TNF-R1 or TNF-R2 plays a pathogenic role in the pathology of colitis and TNF signalling via TNF-R1 or TNF-R2 alone is not sufficient for inducing mucosal damage...
  56. doi request reprint A high-density single-nucleotide polymorphism screen of 23 candidate genes in attention deficit hyperactivity disorder: suggesting multiple susceptibility genes among Chinese Han population
    L Guan
    Department of Child and Adolescent Psychiatry, Institute of Mental Health, Peking University, Beijing, China
    Mol Psychiatry 14:546-54. 2009
    ..05. This study has identified several genes as promising susceptibility loci for ADHD. Replication efforts and further investigations remain necessary to provide definite proof of association...
  57. doi request reprint Association of Epstein-Barr virus reactivation with the recovery of CD4/CD8 double-negative T lymphocytes after haploidentical hematopoietic stem cell transplantation
    Z Bian
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant . 2016
    ..Our findings may facilitate the intervention strategies to improve the overall survival of haploHSCT recipients.Bone Marrow Transplantation advance online publication, 31 October 2016; doi:10.1038/bmt.2016.238...
  58. doi request reprint Minimally invasive retroperitoneoscopic surgery for psoas abscess with thoracolumbar tuberculosis
    X Zhang
    Department of Orthopedics, PLA General Hospital, Fuxing Road 28, Haidian District, Beijing, 100000, China
    Surg Endosc 29:2451-5. 2015
    ..The aim of this study is to introduce and investigate on efficacy and feasibility of MIS (retroperitoneoscopic technique) for PA in patients with thoracolumbar tuberculosis...
  59. doi request reprint Identification of reference microRNAs for quantitative expression analysis in porcine peripheral blood mononuclear cells treated with polyinosinic-polycytidylic acid
    H Wang
    National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing, China
    Int J Immunogenet 42:217-25. 2015
    ..Our study shows the first evidence of careful selection of reference miRNAs in porcine PBMCs and maybe helpful for discovering miRNA biomarkers for double-stranded RNA-induced disease. ..
  60. doi request reprint KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2
    L Jia
    Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Oncogene 35:2040-51. 2016
    ..These findings collectively suggest that TNFAIP2 is a direct KLF5 target gene, and both KLF5 and TNFAIP2 promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42...
  61. pmc Autologous cytokine-induced killer (CIK) cell immunotherapy combined with cyclophosphamide in five patients with POEMS syndrome
    L Ma
    Department of Neurology, Chinese PLA General Hospital, Beijing, China
    Clin Exp Immunol 184:83-9. 2016
    ..CIK cells can improve both the symptoms and quality of life, decrease serum VEGF levels and increase lymphocyte counts in patients with POEMS syndrome. ..
  62. doi request reprint Single nucleotide polymorphisms near the inhibin beta B gene on 2q14 are associated with pre-eclampsia in Han Chinese women
    Q Wang
    National Research Institute for Family Planning, Beijing, China
    Eur J Obstet Gynecol Reprod Biol 193:127-31. 2015
    ..The present study was undertaken to assess the genetic association between these three SNPs and the risk of PE in Han Chinese women...
  63. doi request reprint Postural change from lateral to supine is an important mechanism enhancing cephalic spread after injection of intrathecal 0.5% plain bupivacaine for cesarean section
    F Xu
    Department of Anesthesiology, Peking University Third Hospital, Beijing, China
    Int J Obstet Anesth 24:308-12. 2015
    ..This study was designed to investigate the effect of postural changes on sensory block level...
  64. doi request reprint Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: implications for gene therapy using AAV vectors
    Q Liu
    Division of HIV AIDS and Sex transmitted Virus Vaccines, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
    Gene Ther 21:732-8. 2014
    ..Therefore, AAV5 exposure is low in healthy and HIV-1-infected populations Chinese individuals, and vectors based on AAV5 may be appropriate for human gene therapy or vaccines...
  65. doi request reprint Genetic diversity and expression profiles of cysteine phytases in the sheep rumen during a feeding cycle
    Z Li
    Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China Key Laboratory of Industrial Fermentation Microbiology, Tianjin University of Science and Technology, Tianjin, China
    Lett Appl Microbiol 59:615-20. 2014
    ..Further comparative analysis revealed the dynamic constitution of cysteine phytase genes in rumen at different time points...
  66. pmc Ube2s regulates Sox2 stability and mouse ES cell maintenance
    J Wang
    College of Life Sciences, Capital Normal University, Beijing, China
    Cell Death Differ 23:393-404. 2016
    ..Besides its role in fine-tuning the precise level of Sox2, Ube2s reinforces the self-renewing and pluripotent state of ES cells. Importantly, it also represses Sox2-mediated ES cell differentiation toward the neural ectodermal lineage. ..
  67. pmc Coronary artery fistula in adults: evaluation with dual-source CT coronary angiography
    K Zhou
    1 Department of Radiology, Peking Union Medical College Hospital, Beijing, China
    Br J Radiol 88:20140754. 2015
    ..To evaluate the clinical value of dual-source CT (DSCT) coronary angiography in the diagnosis of coronary artery fistula (CAF) in adults...
  68. doi request reprint Anatomical localization of isocitrate dehydrogenase 1 mutation: a voxel-based radiographic study of 146 low-grade gliomas
    Y Wang
    Beijing Neurosurgical Institute, Capital Medical University, Beijing, China Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
    Eur J Neurol 22:348-54. 2015
    ..The impact of IDH1 mutation on disease prognosis was also evaluated...
  69. doi request reprint Role of periodically rotated overlapping parallel lines with enhanced reconstruction diffusion-weighted imaging in correcting distortion and evaluating head and neck masses using 3 T MRI
    X Chen
    Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
    Clin Radiol 69:403-9. 2014
    ..To investigate the role of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) diffusion-weighted imaging (DWI) in correcting distortion and evaluating head and neck masses...
  70. doi request reprint EBMT risk score can predict the outcome of leukaemia after unmanipulated haploidentical blood and marrow transplantation
    H T Wang
    Peking University People s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
    Bone Marrow Transplant 49:927-33. 2014
    ..Moreover, we also made a haploidentical EBMT (haplo-EBMT) risk score, which used number of HLA disparity instead of donor type, and the haplo-EBMT risk scores can also be used to predict patient outcomes following unmanipulated HBMT. ..
  71. doi request reprint The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity
    Y Wang
    CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
    Oncogene 32:3857-66. 2013
    ..We conclude that Caliban is a regulator of DNA damage-induced apoptosis, functioning as a tumor suppressor in both p53-dependent and -independent pathways...
  72. doi request reprint Diversity of pneumococcal surface protein A (PspA) and relation to sequence typing in Streptococcus pneumoniae causing invasive disease in Chinese children
    J Qian
    Key Laboratory of Major Diseases in Children and National Key Discipline of Pediatrics Capital Medical University, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children s Hospital, Capital Medical University, Nan Lishi Road, Beijing, 100045, China
    Eur J Clin Microbiol Infect Dis 31:217-23. 2012
    ..5%) were the most common types. PspA family 2 and family 1 were dominant among pneumococcal clones isolated from Chinese children with invasive disease. The strains with the same ST always presented in the same PspA family...
  73. doi request reprint Characterization of emm types and superantigens of Streptococcus pyogenes isolates from children during two sampling periods
    Y Ma
    Beijing Children s Hospital, Affiliated to Capital Medical University, Beijing, China
    Epidemiol Infect 137:1414-9. 2009
    ..No significant difference in emm-type distribution and SAg gene profile was noted between isolates from different diseases. These data may contribute towards the development of a GAS vaccine in China...
  74. doi request reprint Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007
    L Ren
    Dr Christophe Mérieux Laboratory, IPB, CAMS Fondation Mérieux and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology IPB, Chinese Academy of Medical Sciences CAMS, Beijing, China
    Clin Microbiol Infect 15:1146-53. 2009
    ..Currently, this study is the largest-scale investigation of respiratory virus infections in China with multiple agent detection, providing baseline data for further studies of respiratory virus infections in adults with ARTIs...
  75. doi request reprint Antibiotic use in pulmonology wards of Chinese children's hospitals: 2002-2006
    W Zhang
    Beijing Children s Hospital, Capital Medical University, Beijing, China
    J Clin Pharm Ther 34:61-5. 2009
    ..To investigate the pattern of antibiotic use in the pulmonology wards of four children's hospitals in China from 2002 to 2006...
  76. doi request reprint The CKLF1-C19 peptide attenuates allergic lung inflammation by inhibiting CCR3- and CCR4-mediated chemotaxis in a mouse model of asthma
    L Tian
    Department of Medical Immunology, School of Basic Medical Science, Peking University Health Science Center, 38 Xueyuan Road, Beijing, China
    Allergy 66:287-97. 2011
    ..Albeit with weaker chemotactic activity, C19 can inhibit chemotaxis induced by both CKLF1 and CCL17. Here, we explore whether C19 can act as an antagonist in the development of asthma...
  77. doi request reprint Automated liquid culture system misses isoniazid heteroresistance in Mycobacterium tuberculosis isolates with mutations in the promoter region of the inhA gene
    Z Zhang
    Respiratory Diseases Department of Nanlou, Chinese People s Liberation Army General Hospital, Beijing, China
    Eur J Clin Microbiol Infect Dis 34:555-60. 2015
    ..In addition, the broth dilution method is more sensitive than MGIT DST in finding INH heteroresistance, indicating that this method may serve as an alternative method to detect the heteroresistance of M. tuberculosis. ..
  78. doi request reprint SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
    B Mao
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Oncogene 33:1468-74. 2014
    ..Together, our findings reveal a new regulatory mechanism of YAP2 by the SIRT1-mediated deacetylation that may be involved in HCC tumorigenesis and drug resistance. ..
  79. doi request reprint Antimicrobial resistance and toxin gene profiles of Staphylococcus aureus strains from Holstein milk
    X Wang
    Key Laboratory of Agricultural Animal Genetics and Breeding, Ministry of Agricultural, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China
    Lett Appl Microbiol 58:527-34. 2014
    ..aureus strains in different farms. These results open new insights into Staph. aureus transmission and antimicrobial resistance of Holstein dairy cows and into developing strategies for udder health improvement of dairy cattle...
  80. doi request reprint Nanoscale distribution of CD20 on B-cell lymphoma tumour cells and its potential role in the clinical efficacy of rituximab
    M Li
    State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China University of Chinese Academy of Sciences, Beijing, China
    J Microsc 254:19-30. 2014
    ..These results can provide novel insights in understanding the rituximab's clinical efficacies from the nanoscale distribution of CD20 on the tumour cells at single-cell and single-molecule levels...
  81. doi request reprint Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
    C Pan
    Chinese PLA General Hospital, Beijing, China
    Diabet Med 25:435-41. 2008
    ..To compare the efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor, vildagliptin, with the alpha glucosidase inhibitor, acarbose, in drug-naive patients with Type 2 diabetes...
  82. doi request reprint Comparisons of 5-aminolevulinic acid photodynamic therapy and after-loading radiotherapy in vivo in cervical cancer
    T Gui
    Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China
    Clin Transl Oncol 15:434-42. 2013
    ..To compare the differences between 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) with traditional after-loading radiotherapy in aspects of efficacies and side effects...
  83. doi request reprint Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation
    Y Zhang
    Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    J Thromb Haemost 10:411-8. 2012
    ..The membrane PHBs have been reported to be involved in typhoid fever, obesity, and cancer metastasis. Proteomic studies have revealed the presence of PHBs in human platelets, but the roles of PHBs during platelet aggregation are unknown...
  84. doi request reprint Treatment of cuff-related tracheal stenosis with a fully covered retrievable expandable metallic stent
    G Chen
    Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
    Clin Radiol 68:358-64. 2013
    ..To investigate the clinical effectiveness, complications, and optimal duration of use of covered retrievable expandable metallic stents in the management of cuff-related tracheal stenosis...
  85. ncbi request reprint The effect of obstructive sleep apnea-hypopnea syndrome on acute myocardial infarction
    W Zhang
    Department of Cardiology, Chinese PLA General Hospital, Beijing, China
    Bratisl Lek Listy 113:565-8. 2012
    ..Obstructive sleep apnea-hypopnea syndrome (OSAHS) is the most clinically common type of sleep-related breathing disorders. In this study, the effect of OSAHS on ST segment elevation myocardial infarction (STEMI) was investigated...
  86. doi request reprint A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells
    G Zhu
    Protein Science Laboratory of the Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
    Oncogene 31:1001-12. 2012
    ..Supporting this conclusion, overexpression of PAK1 is observed in 70% of colon cancer samples and is correlated with massive β-catenin accumulation...
  87. doi request reprint The effect of HLA disparity on clinical outcome after HLA-haploidentical blood and marrow transplantation
    Ming Rui Huo
    Peking University People s Hospital, Peking Peking University Institute of Hematology, Beijing, China
    Clin Transplant 26:284-91. 2012
    ..Our results suggest that prospective matching of patients and donors for HLA-B antigen in the unshared HLA haplotype is warranted for HLA-mismatched/haploidentical transplantation...
  88. ncbi request reprint Highly efficient expression of rabbit neutrophil peptide-1 gene in Chlorella ellipsoidea cells
    Y Chen
    Group 603, Institute of Genetics, Chinese Academy of Sciences, Beijing, PR China
    Curr Genet 39:365-70. 2001
    ..Integration of the gene for NP-1 into the Chlorella genome was confirmed by PCR and Southern blot analysis. In, vitro anti-microbial testes demonstrated the expression of biologically active NP-1 by the transgenic Chlorella cells...
  89. ncbi request reprint Genetic diversity and population history of the red panda (Ailurus fulgens) as inferred from mitochondrial DNA sequence variations
    B Su
    Laboratory of Comparative Genomics, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 18:1070-6. 2001
    ..Interestingly, the effective population size in the Sichuan population was both larger and more stable than that in the Yunnan population, implying a southward expansion from Sichuan to Yunnan...
  90. ncbi request reprint Increase of the expression of midecamycin 4"-hydroxyl propionyltransferase gene (mpt) by a promoter-like fragment from the midecamycin producing strain
    H Gu
    Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China
    Chin J Biotechnol 12:147-52. 1996
    ..lividans TK24 up to 89.02% and 58.53%, respectively, and also enhance the expression in the industrial spiramycin producing strain S. spiramyceticus to a great extent...
  91. ncbi request reprint Enhancement of conflict processing activity in human brain under task relevant condition
    H Wang
    Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, 100053, PR, Beijing, China
    Neurosci Lett 298:155-8. 2001
    ..The mean amplitude of the N270 was more negative in task relevant conflict than in irrelevant conflict. Therefore, the conflict processing activity can be initiated independently of the task, but is enhanced in task relevant conflict...
  92. ncbi request reprint Incidence of nonarteritic anterior ischemic optic neuropathy in adult Chinese: the Beijing Eye Study
    L Xu
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Eur J Ophthalmol 17:459-60. 2007
    ..To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population...
  93. ncbi request reprint Clinical analysis of elderly patients with elderly-onset type 2 diabetes mellitus in China: assessment of appropriate therapy
    Y Wang
    Department of Geriatrics, Beijing Tong Ren Hospital, Capital Medical University, Beijing, China
    J Int Med Res 38:1134-41. 2010
    ..In conclusion, insulin resistance was less severe in elderly-onset diabetes than in usual-onset diabetes. As hyperglycaemia was relatively mild or moderate, oral hypoglycaemic agents might be effective for elderly-onset diabetes...
  94. doi request reprint Indoleamine 2,3-dioxygenase is differentially expressed by different white blood cell populations of rhesus macaques (Macaca mulatta)
    N Lei
    National Center for AIDS STD Control and Prevention, China CDC, 25 Huawei Li, Chaoyang, Beijing, China
    J Med Primatol 42:192-203. 2013
    ..Indoleamine 2,3-dioxygenase (IDO) is involved in immune processes such as transplant and fetal rejection, autoimmunity, cancer, and infection; however, its expression in rhesus macaques has not been fully addressed...
  95. doi request reprint Response to the first wave of pandemic (H1N1) 2009: experiences and lessons learnt from China
    W Liang
    Ministry of Health, People s Republic of China, Beijing, China
    Public Health 126:427-36. 2012
    ....
  96. doi request reprint Clinical and molecular genetic factors affecting postoperative seizure control of 183 Chinese adult patients with low-grade gliomas
    G You
    Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
    Eur J Neurol 19:298-306. 2012
    ..Poor seizure control after surgery has a great adverse impact on quality of life in these patients. The present study aimed to identify clinical and molecular genetic factors that influence postoperative seizure control...
  97. doi request reprint Methicillin-resistant Staphylococcus pseudintermedius isolated from canine pyoderma in North China
    Y Wang
    Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 112:623-30. 2012
    ..To determine the prevalence of carriage of methicillin-resistant Staphylococcus pseudintermedius (MRSP) among dogs with pyoderma from two small animal hospitals in North China during a 21-month period and to characterize these isolates...
  98. doi request reprint Docetaxel plus trans-tracheal injection of adenoviral-mediated p53 versus docetaxel alone in patients with previously treated non-small-cell lung cancer
    X Ning
    Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China
    Cancer Gene Ther 18:444-9. 2011
    ..However, direct trans-tracheal injection of Adp53 proved to be a safe procedure, with tolerable levels of toxicity...
  99. doi request reprint A new method for rapid identification of ansamycin compounds by inactivating KLM gene clusters in potential ansamycin-producing actinomyces
    G Wang
    College of Forest Resources and Environment, Nanjing Forestry University, Nanjing, China
    J Appl Microbiol 112:353-62. 2012
    ....
  100. ncbi request reprint Human insulin from a precursor overexpressed in the methylotrophic yeast Pichia pastoris and a simple procedure for purifying the expression product
    Y Wang
    State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Biotechnol Bioeng 73:74-9. 2001
    ..After tryptic transpeptidation, human insulin with full receptor binding capacity and biological activity was obtained. In the presence of zinc, the recombinant human insulin could be crystallized in the rhombohedral form...
  101. ncbi request reprint Prevention of neurotoxin damage of 6-OHDA to dopaminergic nigral neuron by subthalamic nucleus lesions
    L Chen
    Department of Neurosurgery, Navy General Hospital of PLA, Beijing, China
    Stereotact Funct Neurosurg 75:66-75. 2000
    ..To investigate the possibility that subthalamic nucleus (STN) ablation could prevent the toxicity of the selective dopaminergic neurotoxin 6-hydroxydopamine (6-OHDA)...