Li Liu

Summary

Affiliation: Institute of Chemistry
Country: China

Publications

  1. doi request reprint A metal-free yne-addition/1,4-aryl migration/decarboxylation cascade reaction of alkynoates with Csp(3)-H centers
    De Long Kong
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 14:2210-7. 2016
  2. doi request reprint Highly enantioselective reaction of 2-oxindoles with (3-indolyl)methanols by cooperative catalysis of a Lewis acid and organocatalyst
    Chuan Li Ren
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 12:9881-6. 2014
  3. doi request reprint Highly diastereo- and enantioselective [3+2] annulation of isatin-derived Morita-Baylis-Hillman carbonates with trifluoropyruvate catalyzed by tertiary amines
    Neng Jun Zhong
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:11071-3. 2013
  4. doi request reprint Asymmetric direct α-alkylation of 2-oxindoles with Michler's hydrol catalyzed by bis-cinchona alkaloid-Brønsted acid via an SN1-type pathway
    Tao Zhang
    Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:1636-8. 2013
  5. doi request reprint Cu(II)-catalyzed allylic silylation of Morita-Baylis-Hillman alcohols via dual activation of Si-B bond and hydroxyl group
    Qing Qing Xuan
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 78:11076-81. 2013
  6. doi request reprint Diastereo- and enantioselective [3 + 2] cycloaddition reaction of Morita-Baylis-Hillman carbonates of isatins with N-phenylmaleimide catalyzed by Me-DuPhos
    Yan Wang
    Beijing National Laboratory for Molecular Sciences BNLMS, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 77:4143-7. 2012
  7. doi request reprint Enantioselective tandem reaction of chromone-derived Morita-Baylis-Hillman carbonates with benzylamines catalyzed by a trifunctional organocatalyst: the synthesis of chiral 3-aminomethylene-flavanones
    Neng Jun Zhong
    Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:3697-9. 2013
  8. doi request reprint FeCl3-Mediated Radical Tandem Reactions of 3-Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles
    Hong Ru Wu
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Lett 18:1382-5. 2016
  9. ncbi request reprint Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea
    Tao Zhang
    Beijing National Laboratory for Molecular Sciences BNLMS, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 47:6644-6. 2011
  10. doi request reprint Highly enantioselective and organocatalytic alpha-amination of 2-oxindoles
    Liang Cheng
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Lett 11:3874-7. 2009

Collaborators

Detail Information

Publications25

  1. doi request reprint A metal-free yne-addition/1,4-aryl migration/decarboxylation cascade reaction of alkynoates with Csp(3)-H centers
    De Long Kong
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 14:2210-7. 2016
    ....
  2. doi request reprint Highly enantioselective reaction of 2-oxindoles with (3-indolyl)methanols by cooperative catalysis of a Lewis acid and organocatalyst
    Chuan Li Ren
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 12:9881-6. 2014
    ....
  3. doi request reprint Highly diastereo- and enantioselective [3+2] annulation of isatin-derived Morita-Baylis-Hillman carbonates with trifluoropyruvate catalyzed by tertiary amines
    Neng Jun Zhong
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:11071-3. 2013
    ..An enantioselective [3+2] annulation of Morita-Baylis-Hillman carbonates with trifluoropyruvate catalyzed by modified cinchona alkaloids was developed in good to excellent yields with excellent diastereo- and enantioselectivities. ..
  4. doi request reprint Asymmetric direct α-alkylation of 2-oxindoles with Michler's hydrol catalyzed by bis-cinchona alkaloid-Brønsted acid via an SN1-type pathway
    Tao Zhang
    Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:1636-8. 2013
    ....
  5. doi request reprint Cu(II)-catalyzed allylic silylation of Morita-Baylis-Hillman alcohols via dual activation of Si-B bond and hydroxyl group
    Qing Qing Xuan
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 78:11076-81. 2013
    ..The direct silylation of allylic alcohols via dual activation of the Si-B bond and the hydroxyl group of the MBH alcohol provides an efficient and convenient method for the synthesis of functionalized allylsilanes. ..
  6. doi request reprint Diastereo- and enantioselective [3 + 2] cycloaddition reaction of Morita-Baylis-Hillman carbonates of isatins with N-phenylmaleimide catalyzed by Me-DuPhos
    Yan Wang
    Beijing National Laboratory for Molecular Sciences BNLMS, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 77:4143-7. 2012
    ..This reaction constructs three chiral centers in one step to afford spirocyclopentaneoxindoles in good yields (up to 84%) with excellent diastereo- and enantioselectivies (up to 99% ee)...
  7. doi request reprint Enantioselective tandem reaction of chromone-derived Morita-Baylis-Hillman carbonates with benzylamines catalyzed by a trifunctional organocatalyst: the synthesis of chiral 3-aminomethylene-flavanones
    Neng Jun Zhong
    Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 49:3697-9. 2013
    ....
  8. doi request reprint FeCl3-Mediated Radical Tandem Reactions of 3-Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles
    Hong Ru Wu
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Lett 18:1382-5. 2016
    ..The reaction provided spirocyclohexene oxindoles in good yields and excellent diastereoselectivities via a tandem radical addition/cyclization process. ..
  9. ncbi request reprint Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea
    Tao Zhang
    Beijing National Laboratory for Molecular Sciences BNLMS, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Chem Commun (Camb) 47:6644-6. 2011
    ..A highly enantioselective Michael addition of 2-oxindoles (1) to vinyl selenone (2) in RTILs catalyzed by a Cinchona alkaloid-based thiourea has been developed in high yields (80-91%) with excellent enantioselectivities (up to 95% ee)...
  10. doi request reprint Highly enantioselective and organocatalytic alpha-amination of 2-oxindoles
    Liang Cheng
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Lett 11:3874-7. 2009
    ..The tetrasubstituted chiral carbon center was generated by asymmetric amination of N-unprotected 2-oxindoles with azodicarboxylate catalyzed by commercial biscinchona alkaloids in good to excellent yields with high enantioselectivities...
  11. doi request reprint Fe(III) -Catalyzed Cross-Dehydrogenative Arylation (CDA) between Oxindoles and Arenes under an Air Atmosphere
    Hong Ru Wu
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 P R China
    Chemistry 21:16744-8. 2015
    ..An efficient Fe(III) -catalyzed cross-dehydrogenative arylation (CDA) of 3-substituted oxindoles with activated arenes under an air atmosphere was developed to provide 3,3'-disubstituted oxindoles in good yields. ..
  12. doi request reprint Highly enantioselective [3 + 2]-annulation of isatin-derived morita-baylis-hillman adducts with cyclic sulfonimines
    Feng Wei
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Lett 17:1688-91. 2015
    ..The reaction provides access to heavily substituted aza-spirooxindole derivatives, which also contain ring fused cyclic sultams. ..
  13. doi request reprint Tunable and highly regio- and diastereoselective vinylogous Mannich-type reaction of dioxinone-derived silyl dienolate
    Chun Ling Gu
    Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 74:5754-7. 2009
    ..The procedure for the Ag(I)-catalyzed vinylogous Mannich-type reaction also provided facile access to the alpha-regioisomer with excellent diastereoselectivities (up to >99:1 dr) by changing the counterion of the Ag(I) salt...
  14. doi request reprint A Pd(0)-catalyzed direct dehydrative coupling of terminal alkynes with allylic alcohols to access 1,4-enynes
    Yang Xiong Li
    Beijing National Laboratory for Molecular Sciences BNLMS, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Am Chem Soc 135:12536-9. 2013
    ..The coupling reaction tolerates various functional groups, providing a valuable synthetic tool to access 1,4-enynes. ..
  15. doi request reprint In(III)-catalyzed tandem reaction of chromone-derived Morita-Baylis-Hillman alcohols with amines
    Chen Wu
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 9:253-6. 2011
    ..The tandem allylic amination/chromen ring-opening/Michael cyclization reactions were involved in this protocol...
  16. ncbi request reprint Cascade reaction of β,γ-unsaturated α-ketoesters with phenols in trityl chloride/TFA system. Highly selective synthesis of 4-aryl-2H-chromenes and their applications
    Yan Chao Wu
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 9:2868-77. 2011
    ..Our endeavors will lead to a better understanding of the controlling elements behind their structural motifs. The products were confirmed unambiguously from their spectra and by single-crystal X-ray analysis...
  17. doi request reprint Highly enantioselective [3+2] cycloaddition of vinylcyclopropane with nitroalkenes catalyzed by palladium(0) with a chiral bis(tert-amine) ligand
    Feng Wei
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 China, Fax 86 10 62554614 University of Chinese Academy of Sciences, Beijing 100049 China
    Chemistry 21:2335-8. 2015
    ..The resulting bis(tert-amine)-palladium complex proved to be a highly efficient catalyst for this cycloaddition. ..
  18. ncbi request reprint Efficient construction of pyrazolo[1,5-a]pyrimidine scaffold and its exploration as a new heterocyclic fluorescent platform
    Yan Chao Wu
    Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, No 2 Zhongguancun North 1st Street, Beijing, China
    J Fluoresc 18:357-63. 2008
    ....
  19. doi request reprint Palladium-catalyzed α-regioselective allylic amination of Morita-Baylis-Hillman acetates with simple aromatic amines
    Yan Wang
    Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    Org Biomol Chem 10:6908-13. 2012
    ....
  20. ncbi request reprint Enantioselective organocatalytic anti-Mannich-type reaction of N-unprotected 3-substituted 2-oxindoles with aromatic N-Ts-aldimines
    Liang Cheng
    Beijing National Laboratory for Molecular Sciences BNLMS, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
    J Org Chem 74:4650-3. 2009
    ..A transition model for the anti-diastereo- and enantioselectivity of the reaction was proposed...
  21. doi request reprint Interfacial assembly of amphiphilic styrylquinoxalines: alkyl chain length tunable topochemical reactions and supramolecular chirality
    Li Liu
    Beijing National Laboratory for Molecular Science, CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, The Chinese Academy of Sciences, Beijing, China
    Phys Chem Chem Phys 15:6243-9. 2013
    ....
  22. doi request reprint Photoactivated green fluorescence emission by femtosecond oscillator from indole solutions
    Chen Wang
    State Key Laboratory of High Field Laser Physics, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China
    J Fluoresc 21:2185-91. 2011
    ....
  23. ncbi request reprint TFA-mediated tandem Friedel-Crafts alkylation/cyclization/hydrogen transfer process for the synthesis of flavylium compounds
    Yan Chao Wu
    Beijing National Laboratory for Molecular Science BNLMS, Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, PR China
    J Org Chem 72:9383-6. 2007
    ..As a multifunctional catalyst, TFA mediated the processes efficiently and cleanly...