Xiaoping Miao

Summary

Affiliation: Huazhong University of Science and Technology
Country: China

Publications

  1. doi Reduced RET expression in gut tissue of individuals carrying risk alleles of Hirschsprung's disease
    Xiaoping Miao
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Hum Mol Genet 19:1461-7. 2010
  2. pmc HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B
    Rong Zhong
    Education Key Laboratory of Environment and Health, Department of Epidemiology and Biostatistics and Ministry, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 7:e28839. 2012
  3. pmc Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese: two independent case-control studies
    Li Wang
    Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    PLoS ONE 6:e17608. 2011
  4. pmc Associations between two genetic variants in NKX2-5 and risk of congenital heart disease in Chinese population: a meta-analysis
    Zhenling Wang
    Department of Epidemiology and Biostatistics and State Key Laboratory of Environment Health Incubation, Ministry of Environmental Protection Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e70979. 2013
  5. pmc Smoking and COX-2 functional polymorphisms interact to increase the risk of gastric cardia adenocarcinoma in Chinese population
    Xue Mei Zhang
    Department of Molecular Biology, College of Life Sciences, Hebei United University, Tangshan, China
    PLoS ONE 6:e21894. 2011
  6. pmc An integrated meta-analysis of two variants in HOXA1/HOXB1 and their effect on the risk of autism spectrum disorders
    Ran Ran Song
    Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan, China
    PLoS ONE 6:e25603. 2011
  7. ncbi Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population
    Gang Liang
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences, Beijing 100021, China
    Int J Cancer 105:669-73. 2003
  8. ncbi Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer
    Ming Yang
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 28:1996-2001. 2007
  9. doi Functional variants in cell death pathway genes and risk of pancreatic cancer
    Ming Yang
    Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China
    Clin Cancer Res 14:3230-6. 2008
  10. doi Combined effect of genetic polymorphisms in P53, P73, and MDM2 on non-small cell lung cancer survival
    Li Liu
    Department of Epidemiology and Biostatistics and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Thorac Oncol 6:1793-800. 2011

Collaborators

Detail Information

Publications92

  1. doi Reduced RET expression in gut tissue of individuals carrying risk alleles of Hirschsprung's disease
    Xiaoping Miao
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Hum Mol Genet 19:1461-7. 2010
    ....
  2. pmc HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B
    Rong Zhong
    Education Key Laboratory of Environment and Health, Department of Epidemiology and Biostatistics and Ministry, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 7:e28839. 2012
    ....
  3. pmc Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese: two independent case-control studies
    Li Wang
    Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    PLoS ONE 6:e17608. 2011
    ..This study evaluates the effects of these risk variants in Chinese, where the HBV infection is the most popular in the world...
  4. pmc Associations between two genetic variants in NKX2-5 and risk of congenital heart disease in Chinese population: a meta-analysis
    Zhenling Wang
    Department of Epidemiology and Biostatistics and State Key Laboratory of Environment Health Incubation, Ministry of Environmental Protection Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e70979. 2013
    ..Thus, a meta-analysis was performed to clarify the associations between the two variants and CHD risk in the Chinese population...
  5. pmc Smoking and COX-2 functional polymorphisms interact to increase the risk of gastric cardia adenocarcinoma in Chinese population
    Xue Mei Zhang
    Department of Molecular Biology, College of Life Sciences, Hebei United University, Tangshan, China
    PLoS ONE 6:e21894. 2011
    ..This study aimed to explore the interaction between smoking and functional polymorphisms of COX-2 in modulation of gastric cardia adenocarcinoma (GCA) risk...
  6. pmc An integrated meta-analysis of two variants in HOXA1/HOXB1 and their effect on the risk of autism spectrum disorders
    Ran Ran Song
    Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan, China
    PLoS ONE 6:e25603. 2011
    ..Thus, we conducted a meta-analysis integrating case-control and transmission/disequilibrium test (TDT) studies to clearly discern the effect of these two variants in ASD...
  7. ncbi Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population
    Gang Liang
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences, Beijing 100021, China
    Int J Cancer 105:669-73. 2003
    ..Haplotype analysis with the 2 polymorphisms suggested these polymorphisms might be in linkage disequilibrium with a different causative locus or act together with other functional variants in or close to the XPD locus...
  8. ncbi Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer
    Ming Yang
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 28:1996-2001. 2007
    ..05 [95% confidence interval (CI), 2.50-10.20]. These results suggest that the P53 72Pro and MDM2 309G polymorphisms contribute to the risk of developing GCA...
  9. doi Functional variants in cell death pathway genes and risk of pancreatic cancer
    Ming Yang
    Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China
    Clin Cancer Res 14:3230-6. 2008
    ....
  10. doi Combined effect of genetic polymorphisms in P53, P73, and MDM2 on non-small cell lung cancer survival
    Li Liu
    Department of Epidemiology and Biostatistics and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Thorac Oncol 6:1793-800. 2011
    ....
  11. ncbi Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility
    Yifeng Zhou
    Department of Etiology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 26:1117-21. 2005
    ..001). These results are consistent with our previous findings and further support the hypothesis that gain-of-function of MMP2 resulting from genetic polymorphisms plays an important role in human carcinogenesis...
  12. ncbi Significant increase in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate status
    Wen Tan
    Department of Etiology and Carcinogenesis, Cancer Institute and Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 26:1430-5. 2005
    ..97 (95% CI=5.67-17.53) and 1.88 (95% CI=1.18-3.24) for the normal expression genotype (P=0.002 and 0.029). These results suggest an important role for folate deficiency and impaired TS activity in the etiology of ESCC and GCA...
  13. ncbi Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
    Xuemei Zhang
    Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
    Hum Mutat 27:110-7. 2006
    ..41, 95% CI = 5.26-20.58) for smokers with both the MDM2 GG and TP53 Pro/Pro genotypes. In conclusion, genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 contribute to the risk of developing lung cancer...
  14. ncbi Platelet 12-lipoxygenase Arg261Gln polymorphism: functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms
    Yongli Guo
    Department of Etiology, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Pharmacogenet Genomics 17:197-205. 2007
    ..Inherited polymorphisms in 12-LOX and COX-2 contributed to differential expression or activity of these enzymes might confer interindividual susceptibility to cancer...
  15. ncbi Adenosine diphosphate ribosyl transferase and x-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer
    Xiaoping Miao
    Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Gastroenterology 131:420-7. 2006
    ..This study examined the effects of ADPRT Val762Ala and XRCC1 Arg399Gln polymorphisms on ADPRT-XRCC1 interaction in vitro in cells and their contributions to gastric cardia adenocarcinoma (GCA) risk...
  16. doi Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population
    Rong Zhong
    Department of Epidemiology and Biostatistics and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Mol Carcinog 52:E118-26. 2013
    ..483 × 10(-5), respectively). These findings indicated that the function-validated and potentially functional variations in TERT-CLPTM1L locus, modified by smoking, may play a substantial role in the susceptibility to lung cancer...
  17. ncbi Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer
    Li Wang
    Department of Epidemiology, Institute of Basic Medical Sciences, Cancer Institute and Hospital, Beijing, China
    Clin Gastroenterol Hepatol 3:743-51. 2005
    ..We tested this hypothesis by examining the contribution of functional polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TS) to risk of cancer...
  18. pmc Functional polymorphisms in FAS/FASL system increase the risk of neuroblastoma in Chinese population
    Wei Han
    Department of Surgical Oncology, Beijing Children s Hospital Affiliated to Capital Medical University, Beijing, China
    PLoS ONE 8:e71656. 2013
    ..These findings support the hypothesis that genetic polymorphism in FAS/FASL death system may influence individual susceptibility to neuroblastoma. ..
  19. ncbi Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer
    Xuemei Zhang
    Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing 100 021, China
    Cancer Res 65:722-6. 2005
    ..In conclusion, the ADPRT Val762Ala polymorphism plays an important role in smoking-related lung cancer and the XRCC1 Arg399Gln polymorphism may serve as a risk modifier...
  20. doi Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer
    Yongli Guo
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China
    J Med Genet 47:616-22. 2010
    ..This study examined the functional relevance of missense coding single nucleotide polymorphisms (SNPs) in MAD1L1 and MAD2L1 and their association with susceptibility to lung cancer...
  21. ncbi Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development
    Dongxin Lin
    Department of Etiology and Carcinogenesis, Cancer Institute Hospital, Caoyang District, Beijing, China
    Forum Nutr 60:140-5. 2007
    ..The polymorphisms modulate risk of these cancers associated with low folate status. Our results suggest that MTHFR and TS genotypes may be determinant of gastroesophageal cancers in this at-risk Chinese population...
  22. doi Association between serum uric acid and the metabolic syndrome among a middle- and old-age Chinese population
    Xiayun Dai
    Institute of Occupational Medicine and the Ministry of Education MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Rd, Wuhan, 430030, Hubei, China
    Eur J Epidemiol 28:669-76. 2013
    ..0). These findings suggested that serum uric acid was associated with MetS risk in a middle- and old-age Chinese population. Whether this association was causal remained to be investigated in the future studies. ..
  23. doi Assessment of XPD Lys751Gln and XRCC1 T-77C polymorphisms in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy
    Li Liu
    Department of Epidemiology and Biostatistics, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
    Lung Cancer 73:110-5. 2011
    ..Our findings indicated that neither XPD Lys751Gln nor XRCC1 T-77C could be genetic determinant for prognosis of advanced NSCLC patients treated with platinum-based chemotherapy...
  24. doi Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer
    Li Liu
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Mol Carcinog 52:923-31. 2013
    ..00002). Multi-loci analysis reveals the importance of genetic variations involved in DNA repair and apoptotic pathways in sensitivity of platinum-based chemotherapy in NSCLC...
  25. ncbi The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma
    Yuan Hong
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Cancer Res 65:9582-7. 2005
    ..60; 95% CI, 1.00-2.64; P = 0.049). The P53 and MDM2 polymorphisms may be genetic determinants for the development of ESCC...
  26. doi Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations
    Huan Guo
    Institute of Occupational Medicine and Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, China
    Cancer Res 71:7576-86. 2011
    ..Taken together, our findings define that functional HSPA1B variants are associated with lung cancer risk and survival. These Hsp70 genetic variants may offer useful biomarkers to predict lung cancer risk and prognosis...
  27. doi A functional polymorphism (-1607 1G→2G) in the matrix metalloproteinase-1 promoter is associated with development and progression of lung cancer
    Li Liu
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Cancer 117:5172-81. 2011
    ..The authors hypothesized that this MMP-1 polymorphism may affect susceptibility to the development and progression of cancer...
  28. doi Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer
    Liming Huang
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 34:1001-5. 2013
    ..82, 95% confidence interval = 0.74-0.91, P = 0.0001) in a dominant manner. Our results demonstrate for the first time that common variants in BRCA2 and MAP2K4 are susceptibility to sporadic pancreatic cancer...
  29. ncbi Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population
    Wenfu Lu
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences, Beijing 100 021, China
    Int J Cancer 102:275-9. 2002
    ..3%) but was not associated with risk of lung cancer alone or in combination with the MPO polymorphism. Our results confirm the previous reports showing that the variant A allele of MPO has a protective effect against risk of lung cancer...
  30. ncbi Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer
    Xuemei Zhang
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Gastroenterology 129:565-76. 2005
    ..This study sought to identify functional SNPs in the COX-2 promoter and evaluated their effects on the risk of developing esophageal squamous cell carcinoma (ESCC)...
  31. doi Non-linear dose-response relationship between cigarette smoking and pancreatic cancer risk: evidence from a meta-analysis of 42 observational studies
    Li Zou
    Department of Epidemiology and Biostatistics and State Key Laboratory of Environment Health Incubation, Key Laboratory of Environment and Health of MOE Ministry of Education, Key Laboratory of Environment and Health of Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Eur J Cancer 50:193-203. 2014
    ..Question remains about the shape of the dose-response relationship between cigarette smoking and pancreatic cancer risk...
  32. ncbi [Lung cancer risk associated with genetic polymorphism in myeloperoxidase (-463 G/A) in a Chinese population]
    Wenfu Lu
    Cancer Institute Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
    Zhonghua Zhong Liu Za Zhi 24:250-3. 2002
    ....
  33. doi Risk prediction of esophageal squamous-cell carcinoma with common genetic variants and lifestyle factors in Chinese population
    Jiang Chang
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Carcinogenesis 34:1782-6. 2013
    ..0001). Our results indicate that incorporating genetic variants, lifestyle factors and their interactions in ESCC risk models can be useful for identifying patients with ESCC. ..
  34. pmc Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature
    Ti Zhang
    Department of Epidemiology and Biostatistics and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e59570. 2013
    ..However, the results from these published studies are conflicting. We surveyed the literature (1996-2011) and performed a comprehensive meta-analysis to provide empirical evidence on the association...
  35. ncbi Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma
    Tong Sun
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Natl Cancer Inst 96:1030-6. 2004
    ..We examined the association between these polymorphisms and risk of the development and metastasis of esophageal squamous-cell carcinoma...
  36. doi Association between polymorphisms within the susceptibility region 8q24 and breast cancer in a Chinese population
    Yu Zhang
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health, Wuhan, China
    Tumour Biol 35:2649-54. 2014
    ..The findings suggested that polymorphisms in 8q24 may contribute to susceptibility to BC risk. However, functional studies are warranted to further elucidate the mechanisms of the association...
  37. ncbi Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population
    Zhibin Hu
    Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China
    Int J Cancer 114:455-60. 2005
    ..These results suggest that this p73 dinucleotide polymorphism may have a role in lung cancer susceptibility in our study population. Further studies are needed to elucidate potential functional relevance of the p73 AT variant allele...
  38. pmc The leptin gene family and colorectal cancer: interaction with smoking behavior and family history of cancer
    Li Liu
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 8:e60777. 2013
    ..One mechanism underlying this relationship may involve the growth-promoting effects of the circulation hormones associated with obesity and insulin resistance, such as leptin...
  39. pmc A phosphorylation-related variant ADD1-rs4963 modifies the risk of colorectal cancer
    Na Shen
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 10:e0121485. 2015
    ..This study is the first report of an association between ADD1 and CRC risk, promoting our knowledge of the genetics of CRC. ..
  40. doi Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population
    Rong Zhong
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    Carcinogenesis 34:936-42. 2013
    ..162×10(-6), 8.574×10(-8) and 9.410×10(-8) in combined analyses, respectively. This study emphasized the substantial role of the TGFβ signaling pathway in CRC, especially in interaction with smoking...
  41. doi The SLC4A7 variant rs4973768 is associated with breast cancer risk: evidence from a case-control study and a meta-analysis
    Wei Chen
    Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Breast Cancer Res Treat 136:847-57. 2012
    ..In summary, our results showed that the SLC4A7 variant, rs4973768, is associated with risk of BC although the underlying biologic mechanism warrants further studies...
  42. pmc Prevalence and associated risk factors of dyslexic children in a middle-sized city of China: a cross-sectional study
    Zhao Sun
    Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e56688. 2013
    ..However, to our knowledge, there are few studies focusing on the risk factors of dyslexia in China. Therefore, the aim of our study was to investigate the prevalence of dyslexia and its potential risk factors...
  43. doi Risk of GWAS-identified genetic variants for breast cancer in a Chinese population: a multiple interaction analysis
    Wei Chen
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
    Breast Cancer Res Treat 142:637-44. 2013
    ....
  44. ncbi Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer
    Chunyuan Yu
    Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Cancer Res 64:7622-8. 2004
    ..34; 95% CI = 1.16-9.63). These findings suggest that the C(-1306)-C(-735) haplotype in the MMP-2 promoter contributes to risk of the occurrence and metastasis of esophageal squamous cell carcinoma by increasing expression of MMP-2...
  45. pmc Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies
    Jiaoyuan Li
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 9:e93437. 2014
    ..94 (95% CI: 0.91-0.97) for postmenopausal women, respectively. Our findings demonstrated that mushroom intake may be inversely associated with risk of breast cancer, which need to be confirmed with large-scale prospective studies further...
  46. doi Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations
    Chen Wu
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Nat Genet 43:679-84. 2011
    ..92 × 10(-56)). These findings highlight the involvement of multiple genetic loci and gene-environment interaction in the development of esophageal cancer...
  47. pmc MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer
    Rong Zhong
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
    Sci Rep 5:12202. 2015
    ..The study emphasized that MAD1L1 Arg558His and MAD2L1 Leu84Met can significantly interact with smoking to enhance CRC risk, and the genetic effects of MAD1L1Arg558His on CIN need to be further clarified in follow-up studies. ..
  48. pmc SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer
    Jing Tian
    Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China
    Oncotarget 6:37750-7. 2015
    ..In the future, our novel findings should be further confirmed by functional studies and independent large-scale population studies. ..
  49. doi Reelin gene variants and risk of autism spectrum disorders: an integrated meta-analysis
    Zhenling Wang
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Am J Med Genet B Neuropsychiatr Genet 165:192-200. 2014
    ..67, 95% CI: 0.52-0.86). Our meta-analysis revealed that the RELN rs362691, rather than rs736707 or GGC repeat variant, might contribute significantly to ASD risk...
  50. doi Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple interaction analysis
    Li Liu
    Department of Epidemiology and Biostatistics and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Carcinogenesis 32:336-42. 2011
    ..These results suggest that MMP-2 C-1306T polymorphism is an important risk factor for GCA and the multifactor interactions among polymorphisms in MMP-2, FASL and FAS play more important role in the development of GCA...
  51. pmc The genetic variant on chromosome 10p14 is associated with risk of colorectal cancer: results from a case-control study and a meta-analysis
    Qin Qin
    Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 8:e64310. 2013
    ....
  52. pmc The SNP rs402710 in 5p15.33 is associated with lung cancer risk: a replication study in Chinese population and a meta-analysis
    Xuzai Lu
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Guangdong Maternal and Child Health Care Hospital, Guangzhou, China
    PLoS ONE 8:e76252. 2013
    ..33, was firstly identified to be associated with the lung cancer risk in a genome-wide association study. However, some following replication studies yielded inconsistent results...
  53. doi Genome-wide interrogation identifies YAP1 variants associated with survival of small-cell lung cancer patients
    Chen Wu
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Science, Beijing, China
    Cancer Res 70:9721-9. 2010
    ..These results suggest that YAP1 may play an important role in prognosis of small-cell lung cancer patients treated with platinum-based chemotherapy...
  54. doi No association between XRCC1 polymorphisms and survival in non-small-cell lung cancer patients treated with platinum-based chemotherapy
    Peng Yuan
    Department of Medical Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
    Cancer Biol Ther 10:854-9. 2010
    ....
  55. pmc Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
    Chen Wu
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Nat Genet 44:1090-7. 2012
    ..Our results underscore the direct genetic contribution to ESCC risk, as well as the genetic contribution to ESCC through interaction with alcohol consumption...
  56. ncbi [Risk prediction of colorectal cancer with common genetic variants and conventional non-genetic factors in a Chinese Han population]
    Jiaoyuan Li
    Department of Epidemiology and Biostatistics, School of Public Health
    Zhonghua Liu Xing Bing Xue Za Zhi 36:1053-7. 2015
    ....
  57. doi A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk
    Meian He
    MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    Gut 63:143-51. 2014
    ....
  58. doi Genetic variants in the SWI/SNF complex and smoking collaborate to modify the risk of pancreatic cancer in a Chinese population
    Beibei Zhu
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Mol Carcinog 54:761-8. 2015
    ..03) collaborating with smoking to modify the risk of PC. In conclusion, the current study provides evidence that genetic variants of SWI/SNF may contribute to the susceptibility of PC in the Chinese population...
  59. pmc A genome wide association study identifies common variants associated with lipid levels in the Chinese population
    Li Zhou
    MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China Department of Epidemiology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
    PLoS ONE 8:e82420. 2013
    ..The results from our GWAS provided comprehensive and convincing evidence of the genetic determinants of plasma lipid levels in a Chinese population...
  60. doi Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations
    Chen Wu
    State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Nat Genet 44:62-6. 2012
    ..1 previously reported in populations of European ancestry. These results advance our understanding of the development of pancreatic cancer and highlight potential targets for the prevention or treatment of this cancer...
  61. pmc Parity and pancreatic cancer risk: evidence from a meta-analysis of twenty epidemiologic studies
    Beibei Zhu
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Sci Rep 4:5313. 2014
    ..Findings from this meta-analysis indicate that giving birth to two children has the lowest pancreatic cancer risk, mechanism of this protective effect needs further investigation...
  62. pmc Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese
    Guangfu Jin
    Department of Epidemiology and Biostatistics and Ministry of Education Key Laboratory for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China
    Am J Hum Genet 91:928-34. 2012
    ..20 × 10(-12) and 1.26 × 10(-16), respectively, which are at a genome-wide significance level. Our findings highlight the potential importance of variants at 6p21.1 and 7p15.3 in the susceptibility to multiple cancers...
  63. doi Association between polymorphisms in cdc27 and breast cancer in a Chinese population
    Hui Guo
    Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
    Tumour Biol 36:5299-304. 2015
    ..95, 95 % CI = 1.06-3.59). These findings suggested that polymorphisms in cdc27 may contribute to the susceptibility of BC though functional studies are needed to further elucidate the underling mechanisms of the associations...
  64. pmc The SNP rs961253 in 20p12.3 is associated with colorectal cancer risk: a case-control study and a meta-analysis of the published literature
    Xiawen Zheng
    Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 7:e34625. 2012
    ....
  65. pmc Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma
    Na Shen
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences School of Basic Medicine, Peking Union Medical College, Beijing, China
    PLoS ONE 9:e107246. 2014
    ..032; Group test: P = 0.060). In summary, our study suggested that SERPINA6-rs1998056 regulated by FOXA/ERα might be associated with female HCC risk...
  66. pmc A genetic variant rs1801274 in FCGR2A as a potential risk marker for Kawasaki disease: a case-control study and meta-analysis
    Jiayu Duan
    Department of Epidemiology and Biostatistics and State Key Laboratory of Environment Health, Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 9:e103329. 2014
    ..However, subsequent studies on the role of this SNP were limited and controversial...
  67. doi A genetic variant in microRNA target site of TGF-β signaling pathway increases the risk of colorectal cancer in a Chinese population
    Jing Gong
    State Key Laboratory of Environment Health Incubation, Ministry of Education MOE Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, Wuhan, Hubei, 430030, People s Republic of China
    Tumour Biol 35:4301-6. 2014
    ..04-2.55, P = 0.032). Our study suggested that SNPs in miRNA target sites could contribute to the likelihood of CRC susceptibility and emphasized the important role of polymorphisms at miRNA-regulatory elements in carcinogenesis...
  68. doi Meta-analysis of the association between DCDC2 polymorphisms and risk of dyslexia
    Rong Zhong
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Mol Neurobiol 47:435-42. 2013
    ..In this review, we summarized the ongoing association studies concerning DCDC2 polymorphisms and dyslexia risk by using meta-analysis and revealed that DCDC2 rs807701 might contribute significantly to dyslexia risk...
  69. pmc Longer Sleep Duration and Midday Napping Are Associated with a Higher Risk of CHD Incidence in Middle-Aged and Older Chinese: the Dongfeng-Tongji Cohort Study
    Liangle Yang
    Department of Occupational and Environmental Health and Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Sleep 39:645-52. 2016
    ..To analyze the independent and combined relations of sleep duration and midday napping with coronary heart diseases (CHD) incidence along with the underlying changes of cardiovascular disease (CVD) risk factors among Chinese adults...
  70. ncbi [Research on the association between U2-dependent spliceosome gene and hepatocellular cancer]
    Wei Song
    Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China
    Zhonghua Liu Xing Bing Xue Za Zhi 36:634-8. 2015
    ..To determine the association between U2-dependent spliceosome related 8 key genes and hepatocellular cancer (HCC)...
  71. pmc Association of Adiposity Indices with Platelet Distribution Width and Mean Platelet Volume in Chinese Adults
    Jian Hou
    Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P R China MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P R China
    PLoS ONE 10:e0129677. 2015
    ..Associations between reduced PDW and MPV values and WC, WHtR and BMI values in Chinese female adults may help us to further investigate early changes in human body. ..
  72. doi A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12
    Yongyong Shi
    Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    Nat Genet 45:918-22. 2013
    ..32 and cervical cancer (rs4282438, Pcombined, stringently matched=4.52×10(-27), per-allele ORstringently matched=0.75). Our findings provide new insights into the genetic etiology of cervical cancer...
  73. doi Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers
    Li Liu
    Department of Epidemiology and Biostatistics and Guangdong Key Lab of Molecular Epidemiology, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China
    Cancer Epidemiol 38:66-72. 2014
    ..Considering that rs2352028 might be largely marker-SNP correlated to causative variants, two predicted functional SNPs, rs3759452 and rs7322083, were additionally investigated in this study...
  74. pmc A functional p53 responsive polymorphism in KITLG, rs4590952, does not affect the risk of breast cancer
    Wei Chen
    1 Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 2 State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Sci Rep 4:6371. 2014
    ..Our results suggested that rs4590952 was not associated with the risk of BC in Chinese population, implying that heterogeneous distinct mechanisms might exist in the etiology of different cancers. ..
  75. pmc A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response
    Lu Li
    From the Key Laboratory of Environment and Health, Ministry of Education and Ministry of Environmental Protection, State Key Laboratory of Environmental Health Incubating, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei
    J Biol Chem 290:5328-40. 2015
    ..Notably, the expression of SLC22A3(A) was also suppressed by LPS stimulus. Our findings might indicate a negative feedback mechanism against inflammatory response by which SLC22A3 polymorphisms decreased the risk of CHD. ..
  76. pmc A functional variant rs1820453 in YAP1 and breast cancer risk in Chinese population
    Wei Chen
    State Key Laboratory of Environment Health Incubation, Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e79056. 2013
    ..To investigate the association between rs1820453 which located in the promoter region of yes-associated protein 1 (YAP1) gene and breast cancer (BC) risk...
  77. pmc Dietary legume consumption reduces risk of colorectal cancer: evidence from a meta-analysis of cohort studies
    Beibei Zhu
    State Key Laboratory of Environment Health Incubation, MOE Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health Wuhan, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Sci Rep 5:8797. 2015
    ..73-0.99). Findings from our meta-analysis supported an association between higher intake of legume and a reduced risk of CRC. Further studies controlled for appropriate confounders are warranted to validate the associations...
  78. doi Genetic variant in KIAA0319, but not in DYX1C1, is associated with risk of dyslexia: an integrated meta-analysis
    Li Zou
    Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan, China
    Am J Med Genet B Neuropsychiatr Genet 159:970-6. 2012
    ..In conclusion, our results suggested that the 931C > T variant in KIAA0319, but not the -3G > A in DYX1C1, was significantly associated with the risk of dyslexia...
  79. doi Association between polymorphisms of DRD2 and DRD4 and opioid dependence: evidence from the current studies
    Dingyan Chen
    Department of Epidemiology and Health Statistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China
    Am J Med Genet B Neuropsychiatr Genet 156:661-70. 2011
    ..In conclusion, our results suggested that DRD2 -141ins/delC, DRD2-related TaqI A and DRD4 exon III VNTR polymorphisms might play important roles in the development of opioid dependence...
  80. doi Variants of HSPA1A in combination with plasma Hsp70 and anti-Hsp70 antibody levels associated with higher risk of acute coronary syndrome
    Xiaomin Zhang
    Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Cardiology 119:57-64. 2011
    ....
  81. doi Helicobacter pylori infection is associated with type 2 diabetes among a middle- and old-age Chinese population
    Xu Han
    Institute of Occupational Medicine and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Huazhong University of Science and Technology, Wuhan, China
    Diabetes Metab Res Rev 32:95-101. 2016
    ..Although the association of Helicobacter pylori (H. pylori) infection with diabetes mellitus has been evaluated, findings are controversial. This study investigated the association in a Chinese population...
  82. ncbi [Association between pancreatic cancer risk and the interaction of U2AF65 gene polymorphisms and smoking]
    Jing Tian
    Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China
    Zhonghua Liu Xing Bing Xue Za Zhi 35:710-3. 2014
    ..To determine the association between U2 small nuclear ribonucleoprotein auxiliary factor 35/65 (U2AF35 and U2AF65) and pancreatic cancer (PC)...
  83. doi A functional -77T>C polymorphism in XRCC1 is associated with risk of breast cancer
    Li Liu
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
    Breast Cancer Res Treat 125:479-87. 2011
    ..51) for the TC genotype and 1.53 (95% CI, 1.14-2.07) for the CC genotype compared with the TT genotype. In conclusion, these findings indicated that XRCC1 -77T>C polymorphism may be a genetic determinant for developing breast cancer...
  84. ncbi DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population
    Zhibin Hu
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, Nanjing, China
    Int J Cancer 115:478-83. 2005
    ..These findings indicate that XPC exonic variants may contribute to the risk of lung cancer in the Chinese population, and these variant genotypes may modulate the risk of lung cancer associated with smoking...
  85. doi Allium vegetables and garlic supplements do not reduce risk of colorectal cancer, based on meta-analysis of prospective studies
    Beibei Zhu
    State Key Laboratory of Environment Health Incubation, Ministry of Education Key Laboratory of Environment and Health, Ministry of Environmental Protection Key Laboratory of Environment and Health, and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Clin Gastroenterol Hepatol 12:1991-2001.e1-4; quiz e121. 2014
    ..Laboratory studies have provided evidence that allium vegetables and garlic supplements might protect against colorectal cancer (CRC), but epidemiologic studies have produced inconsistent findings...
  86. doi The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010
    Jinsong Peng
    Wuhan Centers for Disease Prevention and Control, Wuhan, China
    J Med Virol 84:672-8. 2012
    ..3% (196/1,472), which was followed by pH1N1 (159/1,472). It was also noted that the viral distribution pattern in Wuhan changed upon the introduction of the pH1N1 virus...
  87. pmc A common SMAD7 variant is associated with risk of colorectal cancer: evidence from a case-control study and a meta-analysis
    Qibin Song
    Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China
    PLoS ONE 7:e33318. 2012
    ..However, the following replication studies yielded conflicting results...
  88. pmc Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci
    Meian He
    MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Hubei, Wuhan 430030, China
    Hum Mol Genet 24:1791-800. 2015
    ..The findings from this study considerably expand our knowledge of the genetic architecture of human height in Asians. ..
  89. pmc Application of a hybrid model for predicting the incidence of tuberculosis in Hubei, China
    Guoliang Zhang
    Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 8:e80969. 2013
    ..A prediction model for tuberculosis incidence is needed in China which may be used as a decision-supportive tool for planning health interventions and allocating health resources...
  90. pmc Different physical activity subtypes and risk of metabolic syndrome in middle-aged and older Chinese people
    Mu Chen
    MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    PLoS ONE 8:e53258. 2013
    ..Tai chi and dancing are common types of exercise among middle-aged and elderly Chinese. It remains unclear whether these activities are associated with a lower risk of MetS...
  91. pmc The expression levels of plasma micoRNAs in atrial fibrillation patients
    Zheng Liu
    Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    PLoS ONE 7:e44906. 2012
    ..MicroRNA (miRNA) has been found in human blood. It has been increasingly suggested that miRNAs may serve as biomarkers for diseases. We examined the potential of circulating miRNA to serve as predictors of atrial fibrillation (AF)...
  92. ncbi Implications of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 signaling in human neuroblastoma progression
    Elly S W Ngan
    Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, SAR, China, and Department of Pediatric Surgery, The Second Affiliated Hospital of China Medical University, Shenyang, China
    Clin Cancer Res 13:868-75. 2007
    ..In this report, we further elucidate its role in neuroblastoma progression...