Chunhui Deng

Summary

Affiliation: Fudan University
Country: China

Publications

  1. ncbi request reprint Development of gas chromatography-mass spectrometry following microwave distillation and simultaneous headspace single-drop microextraction for fast determination of volatile fraction in Chinese herb
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1152:193-8. 2007
  2. doi request reprint Facile synthesis of TiO2/graphene composites for selective enrichment of phosphopeptides
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Nanoscale 4:1577-80. 2012
  3. doi request reprint Recent advances in inorganic materials for LDI-MS analysis of small molecules
    C Y Shi
    Department of Chemistry and Institutes of Biomedical Sciences, Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200433, China
    Analyst 141:2816-26. 2016
  4. doi request reprint Rational synthesis of novel recyclable Fe₃O₄@MOF nanocomposites for enzymatic digestion
    Man Zhao
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 51:8116-9. 2015
  5. doi request reprint Designed synthesis of MOF-derived magnetic nanoporous carbon materials for selective enrichment of glycans for glycomics analysis
    Nianrong Sun
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, China
    Nanoscale 7:6487-91. 2015
  6. doi request reprint The design and synthesis of a hydrophilic core-shell-shell structured magnetic metal-organic framework as a novel immobilized metal ion affinity platform for phosphoproteome research
    Man Zhao
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 50:6228-31. 2014
  7. doi request reprint High efficiency enrichment of low-abundance peptides by novel dual-platform graphene@SiO2@PMMA
    Peng Yin
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Nanoscale 4:6948-50. 2012
  8. doi request reprint An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS
    Xueyang Zhang
    Department of Chemistry and Institute of Biomedical Science, Fudan University, Shanghai, China
    Chem Commun (Camb) 48:2689-91. 2012
  9. doi request reprint Enrichment and detection of small molecules using magnetic graphene as an adsorbent and a novel matrix of MALDI-TOF-MS
    Chenyi Shi
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 48:2418-20. 2012
  10. ncbi request reprint Development of gas chromatography/mass spectrometry following headspace solid-phase microextraction for fast determination of asarones in plasma
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 20:2120-6. 2006

Collaborators

  • Yan Li
  • Ning Li
  • Ning Yao
  • Yu Mao
  • Peng Yin
  • Yang Liu
  • Gengli Duan
  • Hao Wu
  • Bo Yan
  • Ya Xiong
  • Jie Zhang
  • Wei Zhang
  • Peng Zhang
  • Lijuan Zhang
  • Xiangmin Zhang
  • Jin Lu
  • Pengyuan Yang
  • Dawei Qi
  • Mingxia Gao
  • Ling Dong
  • Hemei Chen
  • Yunfei Sha
  • Danni Huang
  • Man Zhao
  • Zhongbo Li
  • Shuang Lin
  • Yinghua Yan
  • Xizhong Shen
  • Jia Tang
  • Fengli Hu
  • Guoquan Yan
  • Guoping Yao
  • Ruyi Xue
  • Jiaoran Meng
  • Shasha Liu
  • Jiyao Wang
  • Xueyang Zhang
  • Chenyi Shi
  • Xiaohui Lu
  • Shun Shen
  • Nianrong Sun
  • Baizhan Liu
  • Xia Guan
  • Wenjia Yu
  • Huaqing Lin
  • Taotao Liu
  • Jizong Yao
  • Lanting Li
  • C Y Shi
  • Zhifang Zheng
  • Mengyi Wang
  • Shaochun Zhu
  • Chinfai Fu
  • Jinfeng Ren
  • Guangfeng Hong
  • Qing Ye
  • Yang Zhang
  • Si Zhang
  • Xiuqing Xu
  • Zhenxin Lin
  • Junyan Liu
  • Ben Wang
  • Xue Gu
  • Daxi Fu
  • Jiakuan Chen
  • Xiangming Zhang
  • Runqing Wu
  • Chunqing Shang
  • Saijing Zheng
  • Xiaodong Zhang
  • Jing Bu
  • Huanqian Liu
  • Zhiqing Pang
  • Xiaomin Yan
  • Biwen Wei
  • Xinguo Jiang
  • Huili Yang
  • Zhuxing Tang
  • Zhuxin Tang
  • Penyuan Yang
  • Wenyan Xie
  • Haobo Zhang
  • Jianxin Gu
  • Huiying Zhang
  • Dong Yun
  • Zhengqiu Fan
  • Zhen Liu
  • Bei Yang
  • Taomin Huang
  • Keji Hu

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint Development of gas chromatography-mass spectrometry following microwave distillation and simultaneous headspace single-drop microextraction for fast determination of volatile fraction in Chinese herb
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1152:193-8. 2007
    ..The experimental results showed that MD-HS-SDME is a simple, rapid, reliable, and solvent-free technique for the determination of volatile compounds in Chinese herbs...
  2. doi request reprint Facile synthesis of TiO2/graphene composites for selective enrichment of phosphopeptides
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Nanoscale 4:1577-80. 2012
    ....
  3. doi request reprint Recent advances in inorganic materials for LDI-MS analysis of small molecules
    C Y Shi
    Department of Chemistry and Institutes of Biomedical Sciences, Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200433, China
    Analyst 141:2816-26. 2016
    ..On the other hand, this review also summarizes the application of inorganic materials as adsorbents in the selective enrichment of small molecules, which provides a new field for the application of inorganic materials. ..
  4. doi request reprint Rational synthesis of novel recyclable Fe₃O₄@MOF nanocomposites for enzymatic digestion
    Man Zhao
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 51:8116-9. 2015
    ..The magnetic MOF-enzyme composites exhibited significantly improved digestion performance, excellent reusability, stability and reproducibility for different kinds of enzymes. ..
  5. doi request reprint Designed synthesis of MOF-derived magnetic nanoporous carbon materials for selective enrichment of glycans for glycomics analysis
    Nianrong Sun
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, China
    Nanoscale 7:6487-91. 2015
    ..The Co-ZIF-67 materials were successfully applied to glycomics analysis by enriching N-linked glycans in bio-samples with high selectivity and efficiency. ..
  6. doi request reprint The design and synthesis of a hydrophilic core-shell-shell structured magnetic metal-organic framework as a novel immobilized metal ion affinity platform for phosphoproteome research
    Man Zhao
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 50:6228-31. 2014
    ..The as-synthesized Fe3O4@PDA@Zr-MOF composites were successfully applied as a novel immobilized metal ion affinity platform for phosphoproteome research. ..
  7. doi request reprint High efficiency enrichment of low-abundance peptides by novel dual-platform graphene@SiO2@PMMA
    Peng Yin
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Nanoscale 4:6948-50. 2012
    ..For the first time, dual-platform graphene@SiO(2)@poly(methyl methacrylate) (PMMA) material was synthesized, and successfully applied to efficiently enrich low-abundance peptides for mass spectrometry analysis...
  8. doi request reprint An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS
    Xueyang Zhang
    Department of Chemistry and Institute of Biomedical Science, Fudan University, Shanghai, China
    Chem Commun (Camb) 48:2689-91. 2012
    ..High sensitivities were observed both in standard solutions (5 ng mL(-1), 0.86 nM) and serum sample (20 ng mL(-1), 3.4 nM). This method shows great promise in the field of biomarker detection...
  9. doi request reprint Enrichment and detection of small molecules using magnetic graphene as an adsorbent and a novel matrix of MALDI-TOF-MS
    Chenyi Shi
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 48:2418-20. 2012
    ....
  10. ncbi request reprint Development of gas chromatography/mass spectrometry following headspace solid-phase microextraction for fast determination of asarones in plasma
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 20:2120-6. 2006
    ..tatarinowii. The experimental results suggest that the proposed method provides an alternative approach to the PK studies of volatile compounds in TCMs...
  11. ncbi request reprint Fe3O4@Al2O3 magnetic core-shell microspheres for rapid and highly specific capture of phosphopeptides with mass spectrometry analysis
    Yan Li
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Chromatogr A 1172:57-71. 2007
    ..These results show that Fe(3)O(4)@Al(2)O(3) magnetic core-shell microspheres are very good materials for rapid and selective separation and enrichment of phosphopeptides...
  12. doi request reprint Novel Fe3O4@TiO2 core-shell microspheres for selective enrichment of phosphopeptides in phosphoproteome analysis
    Yan Li
    Department of Chemistry, Fudan University, Shanghai, China
    J Proteome Res 7:2526-38. 2008
    ....
  13. doi request reprint Designed synthesis of Graphene @titania @mesoporous silica hybrid material as size-exclusive metal oxide affinity chromatography platform for selective enrichment of endogenous phosphopeptides
    Jizong Yao
    Department of Chemistry and Institutes of Biomedical Sciences, Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai 200433, China
    Talanta 150:296-301. 2016
    ..In addition, the G@TiO2@mSiO2 nanohybrids were employed to capture the endogenous phosphopeptides from human serum successfully...
  14. doi request reprint Cerium ion-chelated magnetic silica microspheres for enrichment and direct determination of phosphopeptides by matrix-assisted laser desorption ionization mass spectrometry
    Yan Li
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Proteome Res 7:1767-77. 2008
    ....
  15. ncbi request reprint On-column tryptic mapping of proteins using metal-ion-chelated magnetic silica microspheres by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    Yan Li
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 21:2263-8. 2007
    ..The ability of regeneration of the prepared on-column microreactor and good reproducibility of microreactor before and after regeneration were also demonstrated...
  16. ncbi request reprint Immobilization of trypsin on superparamagnetic nanoparticles for rapid and effective proteolysis
    Yan Li
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Proteome Res 6:3849-55. 2007
    ....
  17. ncbi request reprint On-chip enzymatic microreactor using trypsin-immobilized superparamagnetic nanoparticles for highly efficient proteolysis
    Junyan Liu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Chromatogr A 1176:169-77. 2007
    ..After a database search, six proteins were identified. This opens a route for its further application in bottom-up proteomic analysis...
  18. doi request reprint Fast and efficient proteolysis by microwave-assisted protein digestion using trypsin-immobilized magnetic silica microspheres
    Shuang Lin
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Anal Chem 80:3655-65. 2008
    ..This new microwave-assisted digestion method will hasten the application of the proteome technique to biomedical and clinical research...
  19. doi request reprint Phosphate-functionalized magnetic microspheres for immobilization of Zr(4+) ions for selective enrichment of the phosphopeptides
    Dawei Qi
    Department of Chemistry, Fudan University, Handan Road, No 220, Shanghai 200433, China
    J Chromatogr A 1217:2606-17. 2010
    ..All the experimental results demonstrate the enrichment efficiency and selectivity of the method we reported here...
  20. doi request reprint Development of mesoporous TiO(2) microspheres with high specific surface area for selective enrichment of phosphopeptides by mass spectrometric analysis
    Jia Tang
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Chromatogr A 1217:2197-205. 2010
    ..These mesoporous TiO(2) microspheres with the ability of large scale synthesis can widely be applied for phosphorylated proteomic research...
  21. doi request reprint Preparation of sandwich-structured graphene/mesoporous silica composites with C8-modified pore wall for highly efficient selective enrichment of endogenous peptides for mass spectrometry analysis
    Peng Yin
    Department of Chemistry, Fudan University, Shanghai, China
    Proteomics 12:2784-91. 2012
    ..The obtained C8-modified graphene@mSiO(2) materials were utilized for size selectively and specifically enriching peptides in standard peptide mixtures and endogenous peptides in real biological samples (mouse brain tissue)...
  22. doi request reprint Development of oleic acid-functionalized magnetite nanoparticles as hydrophobic probes for concentrating peptides with MALDI-TOF-MS analysis
    Hemei Chen
    Center of Analysis and Measurement, Fudan University, Shanghai, P R China
    Proteomics 11:890-7. 2011
    ..Samples of standard peptide solution, protein digest solution and human serum were introduced in the evaluating process, and the OA-Fe(3) O(4) nanoparticles exhibited good surface affinity toward low-concentration peptides...
  23. ncbi request reprint Rapid analysis of essential oil from Fructus Amomi by pressurized hot water extraction followed by solid-phase microextraction and gas chromatography-mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, PR China
    J Pharm Biomed Anal 38:326-31. 2005
    ..S.D. <10.0%). It is shown that PHWE-SPME-GC-MS is an alternative method for the determination of volatile components in TCMs and can be used as a powerful tool for TCM quality assessment...
  24. ncbi request reprint Recent developments and contributions from Chinese scientists in multidimensional separations for proteomics and traditional Chinese medicines
    Mingxia Gao
    Department of Chemistry, Fudan University, Shanghai, China
    J Sep Sci 30:785-91. 2007
    ..In view of the significant contributions from Chinese scientists, this review focuses mainly on the work of Chinese scientists in the above fields...
  25. doi request reprint Facile synthesis of zirconium phosphonate-functionalized magnetic mesoporous silica microspheres designed for highly selective enrichment of phosphopeptides
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, China
    Nanoscale 3:1225-33. 2011
    ..Experimental results demonstrated that zirconium phosphonate-modified magnetic mesoporous silica microspheres show excellent potential for the selective enrichment of phosphopeptides...
  26. doi request reprint Development of core-shell structure Fe3O4@Ta2O5 microspheres for selective enrichment of phosphopeptides for mass spectrometry analysis
    Dawei Qi
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Chromatogr A 1216:5533-9. 2009
    ..Experiment results demonstrate that Ta(2)O(5) coated-magnetic microspheres show the excellent potential for selective enrichment of phosphopeptides...
  27. doi request reprint Preparation of magnetic core-mesoporous shell microspheres with C8-modified interior pore-walls and their application in selective enrichment and analysis of mouse brain peptidome
    Shasha Liu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China
    Proteomics 11:4503-13. 2011
    ..These results indicate C8-Fe(3)O(4)@mSiO(2) microspheres would be a potential candidate for endogenous peptides enrichment and biomarkers discovery in peptidome analysis...
  28. doi request reprint A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry
    Ruyi Xue
    Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Rapid Commun Mass Spectrom 22:3061-8. 2008
    ..The total classifying accuracy of the discriminant function tested by SVM 20-fold cross validation was 75%. This technique is different from traditional ones and appears to be a useful tool in the area of HCC diagnosis...
  29. doi request reprint Novel monolithic enzymatic microreactor based on single-enzyme nanoparticles for highly efficient proteolysis and its application in multidimensional liquid chromatography
    Mingxia Gao
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Chromatogr A 1216:7472-7. 2009
    ..This opens a route for its future application in top-down proteomic analysis...
  30. doi request reprint Hydrothermal synthesis of α-Fe(2)O(3)@SnO(2) core-shell nanotubes for highly selective enrichment of phosphopeptides for mass spectrometry analysis
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Nanoscale 2:1892-900. 2010
    ..The enriched peptides were analyzed by MALDI-MS and LC-ESI MS. Experiment results demonstrate that SnO(2) coated α-Fe(2)O(3) nanotubes show excellent potential for selective enrichment of phosphopeptides...
  31. doi request reprint Preparation of phenyl group-functionalized magnetic mesoporous silica microspheres for fast extraction and analysis of acetaldehyde in mainstream cigarette smoke by gas chromatography-mass spectrometry
    Danni Huang
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Talanta 115:427-34. 2013
    ..25-4 mg/mL (R(2)=0.999). The results indicated that the proposed method based on phenyl-functionalized magnetic mesoporous microspheres was rapid, efficient and convenient for the enrichment and analysis of acetaldehyde in tobacco...
  32. doi request reprint Hydrophilic polydopamine-coated graphene for metal ion immobilization as a novel immobilized metal ion affinity chromatography platform for phosphoproteome analysis
    Yinghua Yan
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Anal Chem 85:8483-7. 2013
    ....
  33. doi request reprint Facile synthesis of Ti(4+)-immobilized Fe3O4@polydopamine core-shell microspheres for highly selective enrichment of phosphopeptides
    Yinghua Yan
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 49:5055-7. 2013
    ..In this work, for the first time, Ti(4+)-Fe3O4@polydopamine microspheres were designed and synthesized for efficient and selective enrichment of phosphopeptides in biological samples...
  34. doi request reprint Synthesis of Fe3O4/graphene/TiO2 composites for the highly selective enrichment of phosphopeptides from biological samples
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    ACS Appl Mater Interfaces 5:7330-4. 2013
    ..The experimental results demonstrate that Fe3O4/graphene/TiO2 composites have a good phosphopeptide enrichment ability. ..
  35. doi request reprint Selective separation and enrichment of peptides for MS analysis using the microspheres composed of Fe3O4@nSiO2 core and perpendicularly aligned mesoporous SiO2 shell
    Hemei Chen
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, P R China
    Proteomics 10:930-9. 2010
    ....
  36. doi request reprint Concanavalin A-immobilized magnetic nanoparticles for selective enrichment of glycoproteins and application to glycoproteomics in hepatocelluar carcinoma cell line
    Jia Tang
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai, PR China
    Proteomics 10:2000-14. 2010
    ....
  37. doi request reprint High throughput enzyme inhibitor screening by functionalized magnetic carbonaceous microspheres and graphene oxide-based MALDI-TOF-MS
    Yang Liu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Am Soc Mass Spectrom 22:2188-98. 2011
    ....
  38. ncbi request reprint Development of microwave-assisted protein digestion based on trypsin-immobilized magnetic microspheres for highly efficient proteolysis followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis
    Shuang Lin
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 21:3910-8. 2007
    ....
  39. ncbi request reprint Highly selective and rapid enrichment of phosphorylated peptides using gallium oxide-coated magnetic microspheres for MALDI-TOF-MS and nano-LC-ESI-MS/MS/MS analysis
    Yan Li
    Department of Chemistry, Institute of Biomedical Sciences, Fudan University, Shanghai, China
    Proteomics 8:238-49. 2008
    ..All results show that Ga(2)O(3)-coated Fe(3)O(4) microsphere is an effective material for selective isolation and concentration of phosphopeptides...
  40. doi request reprint Facile synthesis of C8-functionalized magnetic silica microspheres for enrichment of low-concentration peptides for direct MALDI-TOF MS analysis
    Hemei Chen
    Department of Chemistry, Fudan University, Shanghai, China
    Proteomics 8:2778-84. 2008
    ..In a word, the facile synthesis and efficient enrichment process of the novel C8-f-M-S microspheres make them promising candidates for isolation of peptides even in complex biological samples such as serum, plasma, and urine...
  41. doi request reprint Metabolomic profiling of human urine in hepatocellular carcinoma patients using gas chromatography/mass spectrometry
    Hao Wu
    Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China
    Anal Chim Acta 648:98-104. 2009
    ..The multivariate statistics of the diagnostic model yielded a separation between the two groups with an area under the curve value of 0.9275. This non-invasive technique of identifying HCC biomarkers from urine may have clinical utility...
  42. doi request reprint Facile preparation of magnetic graphene double-sided mesoporous composites for the selective enrichment and analysis of endogenous peptides
    Peng Yin
    Department of Chemistry, Fudan University, Shanghai, China
    Proteomics 13:2243-50. 2013
    ..The enriched endogenous peptides were then analyzed by LC-MS/MS, and 409 endogenous peptides were detected and identified. The results demonstrate that the as-made mag-graphene@mSiO₂ have powerful potential for peptidome research...
  43. doi request reprint Novel microwave-assisted digestion by trypsin-immobilized magnetic nanoparticles for proteomic analysis
    Shuang Lin
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai, China
    J Proteome Res 7:1297-307. 2008
    ..01). This new application of TIMNs in microwave-assisted protein digestion really opens a route for large-scale proteomic analysis...
  44. doi request reprint Highly sensitive thrombin detection by matrix assisted laser desorption ionization-time of flight mass spectrometry with aptamer functionalized core-shell Fe₃O₄@C@Au magnetic microspheres
    Xueyang Zhang
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Talanta 88:295-302. 2012
    ..This simple method holds great potential for analyzing, sensing, purification and preconcentration of proteins in biological fluids...
  45. ncbi request reprint Development of water-phase derivatization followed by solid-phase microextraction and gas chromatography/mass spectrometry for fast determination of valproic acid in human plasma
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 20:1281-7. 2006
    ..All these results show that water-phase derivatization followed by HS-SPME and GC/MS is an alternative and powerful method for fast determination of VPA in biological fluids...
  46. ncbi request reprint Efficient on-chip proteolysis system based on functionalized magnetic silica microspheres
    Yan Li
    Department of Chemistry, Institute of Biomedical Science, Fudan University, Shanghai, China
    Proteomics 7:2330-9. 2007
    ..This microreactor was also successfully applied to the analysis of an RPLC fraction of the rat liver extract. This opens a route for its further application in top-down proteomic analysis...
  47. ncbi request reprint Fast determination of Z-ligustilide in plasma by gas chromatography/mass spectrometry following headspace single-drop microextraction
    Ling Dong
    Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    J Sep Sci 30:1318-25. 2007
    ....
  48. ncbi request reprint On-plate digestion of proteins using novel trypsin-immobilized magnetic nanospheres for MALDI-TOF-MS analysis
    Yan Li
    Department of Chemistry, Institute of Biomedical Sciences, Fudan University, Shanghai, China
    Proteomics 7:3661-71. 2007
    ..These results suggested that our improved on-plate digestion protocol for MALDI-MS may find further application in automated analysis of large sets of proteins...
  49. ncbi request reprint Preparation of Fe3O4@ZrO2 core-shell microspheres as affinity probes for selective enrichment and direct determination of phosphopeptides using matrix-assisted laser desorption ionization mass spectrometry
    Yan Li
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Proteome Res 6:4498-510. 2007
    ..Finally, the Fe3O4@ZrO2 microspheres were successfully utilized for enrichment of phosphopeptides from human blood serum without any other purification procedures...
  50. doi request reprint Integrated strong cation exchange/capillary reversed-phase liquid chromatography/on-target digestion coupled with mass spectrometry for identification of intact human liver tissue proteins
    Mingxia Gao
    Department of Chemistry, Fudan University, Shanghai, 200433, China
    Analyst 133:1261-7. 2008
    ..In total, 458 proteins were identified, which proved the system's promising potential for analysis and application in proteomics...
  51. doi request reprint A novel method to isolate protein N-terminal peptides from proteome samples using sulfydryl tagging and gold-nanoparticle-based depletion
    Lanting Li
    Department of Chemistry, Fudan University, Shanghai, 200433, China
    Anal Bioanal Chem 408:441-8. 2016
    ..The STagAu approach presented is therefore a facile and efficient method for mass-spectrometry-based analysis of proteome N-termini or protease-generated cleavage products...
  52. doi request reprint Facile synthesis of titania nanoparticles coated carbon nanotubes for selective enrichment of phosphopeptides for mass spectrometry analysis
    Yinghua Yan
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Talanta 107:30-5. 2013
    ..These results foresee a promising application of the novel CNTs/TiO2 composites in the selective enrichment of phosphopeptides...
  53. doi request reprint On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis
    Jia Tang
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai, P R China
    Proteomics 9:5046-55. 2009
    ..The relatively small sample amount needed, low detection limit and rapid selective enrichment have made this on-plate strategy promising for online enrichment of glycopeptides, which could be applied in high-throughput proteome research...
  54. ncbi request reprint Rapid determination of C6-aldehydes in tomato plant emission by gas chromatography-mass spectrometry and solid-phase microextraction with on-fiber derivatization
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Sep Sci 28:172-6. 2005
    ..1 to 0.5 ng/L and good precision (RSD less than 10%). In this work, the method was applied to investigation of tomato plant defense response to Helicoverpa armigera...
  55. ncbi request reprint Comparison of solid-phase microextraction, supercritical fluid extraction, steam distillation, and solvent extraction techniques for analysis of volatile consituents in Fructus Amomi
    Shun Shen
    Fudan University, Department of Chemistry, Shanghai 200433, People s Republic of China
    J AOAC Int 88:418-23. 2005
    ..Due to SFE's requirement for expensive specialized instrumentation, the simplicity, low cost, and speed of SPME make it a more appropriate technique for extraction of volatile constituents in TCMs...
  56. ncbi request reprint Rapid determination of methyl salicylate, a plant-signaling compound, in tomato leaves by direct sample introduction and thermal desorption followed by GC-MS
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai, China
    J Sep Sci 28:1137-42. 2005
    ..It was found that tomato plants can produce large amounts of MeSA as a defense response to TMV. This indicates that MeSA may be a plant-signaling compound in tomato plant defense response to TMV...
  57. ncbi request reprint Fast determination of paeonol in plasma by headspace solid-phase microextraction followed by gas chromatography-mass spectrometry
    Ling Dong
    Zhongshan Hosptial, Medical College of Shanghai, Fudan University, Shanghai 200433, China
    Anal Chim Acta 585:76-80. 2007
    ..The experimental results suggest that the proposed method provided an alternative and novel approach to the pharmacokinetics study of paeonol in the TCMs...
  58. ncbi request reprint A simple pathway to the synthesis of magnetic nanoparticles with immobilized metal ions for the fast removal of microcystins in water
    Mingxia Gao
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, PR China
    Small 3:1714-7. 2007
  59. doi request reprint Large scale depletion of the high-abundance proteins and analysis of middle- and low-abundance proteins in human liver proteome by multidimensional liquid chromatography
    Mingxia Gao
    Department of Chemistry and Research Center of Proteome, Fudan University, Shanghai, China
    Proteomics 8:939-47. 2008
    ..The strategy increases greatly the number of identified proteins and around 1213 proteins were identified, which was about 2.7 times as that of the nondepletion method...
  60. doi request reprint Investigation of volatile biomarkers in liver cancer blood using solid-phase microextraction and gas chromatography/mass spectrometry
    Ruyi Xue
    Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    Rapid Commun Mass Spectrom 22:1181-6. 2008
    ..These results show that SPME-GC/MS is a simple, rapid and sensitive method for the investigation of volatile disease markers in human blood...
  61. doi request reprint Functionalized magnetic carbonaceous microspheres for trypsin immobilization and the application to fast proteolysis
    Guoping Yao
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1215:82-91. 2008
    ..After database search, 485 proteins (p<0.01) were identified when the extract was digested by the microspheres. This opens a route for its future application in bottom-up proteomic analysis...
  62. doi request reprint Intact-protein trapping columns for proteomic analysis in capillary high-performance liquid chromatography
    Xia Guan
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1217:6875-81. 2010
    ..Results demonstrated high efficiency of the monolithic trapping columns for trapping intact proteins for proteomic analysis in on-line capillary liquid chromatography system...
  63. doi request reprint Preparation of magnetic core mesoporous shell microspheres with C18-modified interior pore-walls for fast extraction and analysis of phthalates in water samples
    Zhongbo Li
    Department of Chemistry, Fudan University, No 220, Handan Road, Shanghai 200433, China
    J Chromatogr A 1218:6232-9. 2011
    ..The results indicated that this novel method was fast, convenient and efficient for the target compounds and could avoid being interfered by macromolecules...
  64. ncbi request reprint Gas chromatography-mass spectrometry following microwave distillation and headspace solid-phase microextraction for fast analysis of essential oil in dry traditional Chinese medicine
    Ning Li
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1133:29-34. 2006
    ..All experimental results show that the proposed method is an alternative tool for fast analysis of essential oils in dry TCMs...
  65. doi request reprint Facile synthesis of magnetic metal organic frameworks for the enrichment of low-abundance peptides for MALDI-TOF MS analysis
    Man Zhao
    Department of Chemistry, Fudan University, Shanghai, China
    Proteomics 13:3387-92. 2013
    ..In brief, the facile synthesis and efficient enrichment process of the Fe3 O4 @[Cu3 (btc)2 ] microspheres make them promising candidates for the isolation of peptides in even complex biological environments. ..
  66. doi request reprint Facile synthesis of Fe3O4@mesoporous TiO2 microspheres for selective enrichment of phosphopeptides for phosphoproteomics analysis
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Talanta 105:20-7. 2013
    ..Due to that the as-made Fe3O4@mesoporous TiO2 microspheres have large surface area, good dispersivity and biocompatibility, they have been demonstrated as a powerful tool for phosphoproteomics research...
  67. doi request reprint Morphine-induced conditioned place preference in mice: metabolomic profiling of brain tissue to find "molecular switch" of drug abuse by gas chromatography/mass spectrometry
    Jiaoran Meng
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Anal Chim Acta 710:125-30. 2012
    ..947. Some metabolites were further discussed in detail about their pathway. Results showed that our technique can be successfully applied to profile for biomarkers and in understanding molecular mechanisms of drug abuse...
  68. doi request reprint Facile synthesis of superparamagnetic Fe3O4@Au nanoparticles for photothermal destruction of cancer cells
    Jinfeng Ren
    School of Pharmacy and Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, Fudan University, Shanghai, China
    Chem Commun (Camb) 47:11692-4. 2011
    ..The as-synthesized nanocomposites were successfully applied to photothermal destruction of cancer cells...
  69. ncbi request reprint Development of microwave-assisted derivatization followed by gas chromatography/mass spectrometry for fast determination of amino acids in neonatal blood samples
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Rapid Commun Mass Spectrom 19:2227-34. 2005
    ..The results demonstrated that microwave-assisted silylation followed by GC/MS is a rapid, simple and sensitive method for amino acid analysis and is also a potential tool for fast screening of neonatal aminoacidurias...
  70. ncbi request reprint Diagnosis of congenital adrenal hyperplasia by rapid determination of 17alpha-hydroxyprogesterone in dried blood spots by gas chromatography/mass spectrometry following microwave-assisted silylation
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, P R China
    Rapid Commun Mass Spectrom 19:2974-8. 2005
    ..The proposed technique has been shown to have potential as a powerful tool for the rapid diagnosis of neonatal CAH...
  71. ncbi request reprint Simultaneous determination of blood glucose and isoleucine levels in rats after chronic alcohol exposure by microwave-assisted derivatization and isotope dilution gas chromatography/mass spectrometry
    Ruyi Xue
    Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    Rapid Commun Mass Spectrom 22:245-52. 2008
    ..The combination of MAD and ID GC/MS has been shown to be an accurate, rapid, simple and sensitive method for the quantification of glucose and isoleucine in serum samples...
  72. doi request reprint Enrichment of peptides in serum by C(8)-functionalized magnetic nanoparticles for direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis
    Ning Yao
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1185:93-101. 2008
    ..Finally, the C(8)-magnetic nanoparticles were successfully applied to fast and efficient enrichment of low-abundance peptides from protein tryptic digestion and human serum followed by MALDI-TOF-MS analysis...
  73. doi request reprint Quantitative determination of chlorogenic acid in Honeysuckle using microwave-assisted extraction followed by nano-LC-ESI mass spectrometry
    Fengli Hu
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Talanta 77:1299-303. 2009
    ..5 ng mL(-1)), good precision (R.S.D.=2.54%) and a recovery (84.8%). The experiment has demonstrated that the nano-LC-ESI/MS following MAE is a fast and reliable method for quantitative analysis of CA in Honeysuckle...
  74. doi request reprint Preparation of C60-functionalized magnetic silica microspheres for the enrichment of low-concentration peptides and proteins for MALDI-TOF MS analysis
    Hemei Chen
    Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai, China
    Proteomics 9:380-7. 2009
    ....
  75. ncbi request reprint Determination of camphor and borneol in Flos Chrysanthemi Indici by UAE and GC-FID
    Qing Ye
    Department of Chemistry, Shangrao Normal University, Shangrao 334001, China
    J Chromatogr Sci 47:287-90. 2009
    ..It has been shown that the proposed UAE-GC-FID is a simple, rapid, and reliable method for quantitative analysis of camphor and borneol in TCM, and a potential tool for quality assessment of Flos Chrysanthemi Indici...
  76. doi request reprint Metabolomic investigation of gastric cancer tissue using gas chromatography/mass spectrometry
    Hao Wu
    Department of Gastroenterology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Anal Bioanal Chem 396:1385-95. 2010
    ..969. We conclude that the metabolomic profile of malignant gastric tissue was different from normal, and that the selected tissue metabolites could probably be applied for clinical diagnosis or staging for gastric cancer...
  77. doi request reprint Fast determination of chlorogenic acid in tobacco residues using microwave-assisted extraction and capillary zone electrophoresis technique
    Zhongbo Li
    Department of Chemistry, Fudan University, No 220, Handan Road, Shanghai 200433, China
    Talanta 82:1181-5. 2010
    ..The experiment results have demonstrated that the CZE combined with MAE is a convenient, fast, economical and reliable method for the determination of CA in tobacco residues...
  78. ncbi request reprint Capillary array reversed-phase liquid chromatography-based multidimensional separation system coupled with MALDI-TOF-TOF-MS detection for high-throughput proteome analysis
    Xue Gu
    Department of Chemistry and Research Center of Proteome, Fudan University, Shanghai 200433, China
    J Proteome Res 5:3186-96. 2006
    ..A total of 462 proteins was identified, which proved the system's promising potential for high-throughput analysis and application in proteomics...
  79. ncbi request reprint Development of headspace solid-phase microextraction with on-fiber derivatization for determination of hexanal and heptanal in human blood
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr B Analyt Technol Biomed Life Sci 813:47-52. 2004
    ..The experimental results showed that GC-MS and HS-SPME with on-fiber derivatization is a simple, rapid, sensitive and solvent-free method for determination of in hexanal and heptanal human blood...
  80. ncbi request reprint Application of HS-SPME and GC-MS to characterization of volatile compounds emitted from Osmanthus flowers
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, PR China
    Ann Chim 94:921-7. 2004
    ..fragrans var. latifolius were 39.46% and 0.51%, while in O. fragrans var. thunbergii were 9.53% and 27.71%. Due to their different relative contents, the two varieties of flower have different fragrances...
  81. ncbi request reprint Gas chromatography-mass spectrometric analysis of hexanal and heptanal in human blood by headspace single-drop microextraction with droplet derivatization
    Ning Li
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Anal Biochem 342:318-26. 2005
    ..Due to sample extraction, concentration, and derivatization being performed in a single step, the method provided a simple, rapid, low-cost, and efficient approach to analysis of aldehydes in blood samples...
  82. doi request reprint Enzyme inhibitor screening by electrospray mass spectrometry with immobilized enzyme on magnetic silica microspheres
    Fengli Hu
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Am Soc Mass Spectrom 19:865-73. 2008
    ..The inhibition was determined by measuring a decrease of product formation using ESI-MS...
  83. doi request reprint Development of magnetic multiwalled carbon nanotubes as solid-phase extraction technique for the determination of p-hydroxybenzoates in beverage
    Danni Huang
    Department of Chemistry, Fudan University, Shanghai, China
    J Sep Sci 35:1667-74. 2012
    ....
  84. doi request reprint Facile synthesis of alumina hollow spheres for on-plate-selective enrichment of phosphopeptides
    Jin Lu
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 47:5334-6. 2011
    ..This provides a fast and efficient on-plate selective enrichment method for phosphopeptides investigation...
  85. ncbi request reprint Rapid determination of amino acids in neonatal blood samples based on derivatization with isobutyl chloroformate followed by solid-phase microextraction and gas chromatography/mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, P R China
    Rapid Commun Mass Spectrom 18:2558-64. 2004
    ..The results showed that the proposed method is a potentially powerful tool for simultaneous screening for neonatal PKU and MSUD...
  86. ncbi request reprint Development of pressurized hot water extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry for determination of ligustilides in Ligusticum chuanxiong and Angelica sinensis
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai, China
    J Sep Sci 28:1237-43. 2005
    ..The method was applied to determination of ligustildes in the TCMs from different growing areas. The results indicate that PHWE-HS-SPME-GC-MS is a potential tool for TCM quality assessment...
  87. ncbi request reprint Fast determination of curcumol, curdione and germacrone in three species of Curcuma rhizomes by microwave-assisted extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1117:115-20. 2006
    ..The results show that MAE-HS-SPME is a simple, rapid, solvent-free and reliable method for the determination of curdione, curcumol and germacrone in TCM, and also a potential and powerful tool for quality assessment of Rhizoma Curcuma...
  88. ncbi request reprint Recent developments in sample preparation techniques for chromatography analysis of traditional Chinese medicines
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 2004433, China
    J Chromatogr A 1153:90-6. 2007
    ....
  89. ncbi request reprint Separation and identification of volatile constituents in Artemisia argyi flowers by GC-MS with SPME and steam distillation
    Ning Li
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr Sci 46:401-5. 2008
    ..These results show that Artemisia argyi flowers as well as leaves might be used as TCM...
  90. doi request reprint Development of high performance liquid chromatography with immobilized enzyme onto magnetic nanospheres for screening enzyme inhibitor
    Fengli Hu
    Department of Chemistry, Fudan University, Shanghai, China
    J Chromatogr B Analyt Technol Biomed Life Sci 871:67-71. 2008
    ..The approach is general and offers many attractive advantages including easy product isolation, inexpensive cost, and high efficiency in terms of reagent consumption...
  91. doi request reprint Fast field analysis of short-chain aliphatic amines in water using solid-phase microextraction and a portable gas chromatograph
    Huaqing Lin
    Department of Chemistry, Fudan University, Shanghai, China
    J Sep Sci 31:3225-30. 2008
    ..Finally, the proposed method was further applied to the quantification of ethylamine, propylamine, and butylamine in environmental water...
  92. doi request reprint High throughput identification of components from traditional Chinese medicine herbs by utilizing graphene or graphene oxide as MALDI-TOF-MS matrix
    Yang Liu
    Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    J Mass Spectrom 46:804-15. 2011
    ..In summary, the promoted MALDI-TOF-MS methodology was demonstrated to be simple, sensitive, fast, cost effective and, most importantly, high throughput...
  93. doi request reprint Facile synthesis of water-soluble multi-wall carbon nanotubes and polyaniline composites and their application in detection of small metabolites by matrix assisted laser desorption/ionization mass spectrometry
    Jiaoran Meng
    Department of Chemistry and Institutes of Biomedical Science, Fudan University, Shanghai 200433, China
    Chem Commun (Camb) 47:11017-9. 2011
    ....
  94. ncbi request reprint Facile synthesis and application of mesoporous silica coated magnetic carbon nanotubes
    Xiaohui Lu
    Center for Analysis and Measurement, Fudan University, Shanghai, China
    Chem Commun (Camb) 47:1210-2. 2011
    ..Mesoporous silica coated magnetic carbon nanotubes were prepared as a novel hybrid material for the first time, and the as-synthesized composites were successfully applied as absorbents for the fast removal of microcystins...
  95. ncbi request reprint Rapid determination of essential oil in Acorus tatarinowii Schott. by pressurized hot water extraction followed by solid-phase microextraction and gas chromatography-mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, PR China
    J Chromatogr A 1059:149-55. 2004
    ..S.D. less than 13.0%) and recovery (92% for alpha-asarone). It has been shown that PHWE-SPME-GC-MS is an alternative method for determination of essential oils in TCMs and a potential tool for TCM quality assessment...
  96. ncbi request reprint Development of microwave-assisted extraction followed by headspace single-drop microextraction for fast determination of paeonol in traditional Chinese medicines
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr A 1103:15-21. 2006
    ..paniculatum and P. suffruticosa...
  97. ncbi request reprint Rapid determination of volatile compounds emitted from Chimonanthus praecox flowers by HS-SPME-GC-MS
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    Z Naturforsch C 59:636-40. 2004
    ....
  98. doi request reprint Microwave-assisted silylation followed by gas chromatography/mass spectrometry for rapid determination of ergosterol in cigarettes
    Yunfei Sha
    Shanghai Tobacco Group Corporation Technical Center, Shanghai, China
    J Sep Sci 31:2451-6. 2008
    ..Finally it was successfully applied to the analysis of ergosterol in normal and mildewy cigarettes...
  99. ncbi request reprint Rapid determination of volatile constituents of Michelia alba flowers by gas chromatography-mass spectrometry with solid-phase microextraction
    Chunqing Shang
    Center for Analysis and Measurement, Fudan University, Shanghai, China
    J Chromatogr A 942:283-8. 2002
    ..In this study, headspace SPME-GC-MS afforded a simple and more sensitive sampling method for fresh Michelia alba flowers and other fresh flowers...
  100. ncbi request reprint Rapid diagnosis of phenylketonuria and other aminoacidemias by quantitative analysis of amino acids in neonatal blood spots by gas chromatography-mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, 200433 Shanghai, PR China
    J Chromatogr B Analyt Technol Biomed Life Sci 775:115-20. 2002
    ..Because of the low cost, this neonatal screening method is suited to application in developing countries such as China...
  101. ncbi request reprint Gas chromatography-mass spectrometry method for determination of phenylalanine and tyrosine in neonatal blood spots
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, China
    J Chromatogr B Analyt Technol Biomed Life Sci 780:407-13. 2002
    ..The present method only took a few minutes to perform and required minimal sample preparation. In addition it provided low detection limits of 1.2 micromol l(-1) for Phe and 1.6 micromol l(-1)for Tyr...