Pingbo Huang

Summary

Affiliation: Clear Water Bay
Country: China

Publications

  1. ncbi request reprint Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium
    Pingbo Huang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    Proc Am Thorac Soc 1:33-7. 2004
  2. doi request reprint Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 294:C1443-53. 2008
  3. doi request reprint Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Pflugers Arch 456:929-38. 2008
  4. doi request reprint Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia
    Changyan Xie
    Division of Life Science, Division of Biomedical Engineering, and State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong, China
    FASEB J 30:1579-89. 2016
  5. pmc A novel mechanism of control of NFκB activation and inflammation involving A2B adenosine receptors
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Cell Sci 125:4507-17. 2012
  6. ncbi request reprint Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Division of Life Science, HKUST, Clear Water Bay, Kowloon, Hong Kong
    Biochem J . 2016
  7. ncbi request reprint Adenosine promotes IL-6 release in airway epithelia
    Ying Sun
    Department of Biology, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Immunol 180:4173-81. 2008
  8. doi request reprint Intracellular spatial control of fluorescent magnetic nanoparticles
    Jinhao Gao
    Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China
    J Am Chem Soc 130:3710-1. 2008
  9. ncbi request reprint Regulation of CFTR channels by HCO(3)--sensitive soluble adenylyl cyclase in human airway epithelial cells
    Yan Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 289:C1145-51. 2005
  10. ncbi request reprint Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    Anthony P Barnes
    Department of Cell and Developmental Biology and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 280:7997-8003. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium
    Pingbo Huang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    Proc Am Thorac Soc 1:33-7. 2004
    ..Inhibition of ENaC by P2Y2 receptors appears to be mediated by phospholipase C-beta3, possibly through an effect on the levels of phosphatidylinositol 4,5-bisphosphonate in the apical membrane...
  2. doi request reprint Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 294:C1443-53. 2008
    ..Our findings provide novel mechanistic insights into the regulation of anion section by adenosine, a key player in the airway surface liquid homeostasis and mucociliary clearance...
  3. doi request reprint Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Pflugers Arch 456:929-38. 2008
    ..Our data suggest that GPCR-mediated signaling maintain their integrity after lipid raft disruption in Calu-3 and T84 epithelial cells and cast doubts on the role of lipid rafts as signaling platforms in GPCR-mediated signaling...
  4. doi request reprint Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia
    Changyan Xie
    Division of Life Science, Division of Biomedical Engineering, and State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong, China
    FASEB J 30:1579-89. 2016
    ..Zhang, W. K., Sun, Y., Hu, W., Zhou, Z., Wang, Y., Huang, P. Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia. ..
  5. pmc A novel mechanism of control of NFκB activation and inflammation involving A2B adenosine receptors
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Cell Sci 125:4507-17. 2012
    ..Our findings unveil a surprising function for the A(2B)AR, and provide a novel mechanistic insight into the control of the NFκB pathway and inflammation...
  6. ncbi request reprint Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Division of Life Science, HKUST, Clear Water Bay, Kowloon, Hong Kong
    Biochem J . 2016
    ..By contrast, actinin-4, another non-muscle actinin isoform, did not bind to A2BAR. Thus, our findings reveal a previously unidentified regulatory mechanism of A2BAR abundance...
  7. ncbi request reprint Adenosine promotes IL-6 release in airway epithelia
    Ying Sun
    Department of Biology, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Immunol 180:4173-81. 2008
    ..Our findings provide a possible molecular link between extracellular adenosine elevation and lung inflammation and fibrosis...
  8. doi request reprint Intracellular spatial control of fluorescent magnetic nanoparticles
    Jinhao Gao
    Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China
    J Am Chem Soc 130:3710-1. 2008
    ..Confocal images indicate that the uptaken nanoparticles can be manipulated using a small magnet. The successful intracellular manipulation of magnetic nanoparticles may offer a new strategy for studying polarized cells...
  9. ncbi request reprint Regulation of CFTR channels by HCO(3)--sensitive soluble adenylyl cyclase in human airway epithelial cells
    Yan Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 289:C1145-51. 2005
    ....
  10. ncbi request reprint Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    Anthony P Barnes
    Department of Cell and Developmental Biology and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 280:7997-8003. 2005
    ..These findings underscore the concept that subcellular localization of individual PDE isozymes is an important mechanism for confining cAMP signaling to functional domains within cells...
  11. pmc Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
    Seiko F Okada
    Cystic Fibrosis Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Gen Physiol 124:513-26. 2004
    ..However, the observation that VDAC-1 knockout cells released a significant amount of ATP suggests that other molecules also play a role in this function...