Li Liu

Summary

Affiliation: Chinese Academy of Medical Sciences
Country: China

Publications

  1. ncbi request reprint NOK mediated mitogenic signaling is altered by P203L and V395I mutations
    Sheng Qi Hou
    Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Uion Medical College, Beijing 100005, China
    Front Biosci (Landmark Ed) 20:1179-89. 2015
  2. pmc Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal transducers and activators of transcription factor 3 signalin
    Wei Ye Shi
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Int J Mol Sci 14:24656-69. 2013
  3. ncbi request reprint Characterization of an upstream regulatory element of adenovirus L1 poly (A) site
    Li Liu
    Department of Microbiology and Etiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    Virology 337:124-35. 2005
  4. doi request reprint Identification and characterization of three novel small interference RNAs that effectively down-regulate the isolated nucleocapsid gene expression of SARS coronavirus
    Ying li Cao
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, China
    Molecules 16:1544-58. 2011
  5. pmc Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques
    Li Liu
    AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People s Republic of China
    J Virol 85:4025-30. 2011
  6. doi request reprint MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway
    Rong Guo
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Molecules 17:14733-47. 2012
  7. pmc Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway
    Wei Ye Shi
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Int J Mol Sci 17:. 2016
  8. pmc The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism
    Yi Wang
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China
    MBio 7:e01872-15. 2016
  9. doi request reprint microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture
    Guangwei Xu
    School of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, 5 Dongdan Santiao, Beijing 100005, China National Institute of Biological Sciences, Beijing, 7 Science Park Road, Zhongguancun Life Science Park, Changping, Beijing 102206, China
    Virology 448:247-54. 2014
  10. ncbi request reprint Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells
    Xiang Yue Zhang
    Department of Microbiology and Etiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China
    Immunogenetics 57:934-43. 2006

Collaborators

  • Gang Wang
  • Jian Wu
  • Cheng Cao
  • Tao Cai
  • Bin Liu
  • Hong Jiang
  • Hua Zhu
  • Yan Wang
  • Hui Zhao
  • Yan Zhao
  • Debomoy Lahiri
  • Jie Xu
  • Wei Ye Shi
  • De Hua Wu
  • Sheng Qi Hou
  • Yi Wen
  • Rong Guo
  • Long Hua Chen
  • Guangwei Xu
  • Chen Wang
  • Hong Tang
  • Ying li Cao
  • Shu Hui Wang
  • Yun Zhang
  • Junfeng Su
  • Lit Fui Lau
  • Lili Wang
  • Emmanuel Planel
  • Xiang Bo Wan
  • Mathieu Herman
  • Jingjing Luo
  • Guang Yu
  • Jie Chen
  • Ze Jun Liu
  • Liang Zhao
  • Jun Zhang
  • Shuang Wang
  • Chun Han
  • Xiang Yue Zhang
  • Ralph P Mason
  • Hui Zhong Zhang
  • Song Wang
  • Yu Rong
  • Yan qing Ding
  • Fang He
  • Bo He
  • Jie An
  • Gang Cai
  • Rakhee S Gupte
  • Naihe Jing
  • Xin A Zhang
  • Leping Cheng
  • Suneil K Kalia
  • Bin Zhou
  • Jianxin Yu
  • Scott M Wilhelm
  • Takashi Sakai
  • Wenhui He
  • Fengmin Lu
  • Xiaofeng Feng
  • Wenhui Li
  • Zhenchao Gao
  • Yanting Ma
  • Chang yan Che
  • Fan Yang
  • Thomas Maurin
  • Isabelle Marie
  • Min Gong
  • Pavan Krishnamurthy
  • Wei Zhang
  • Xue Fei Huang
  • Helen Figueroa
  • W Haung Yu
  • Chen Lv
  • Rui Zhang
  • Wai Haung Yu
  • Liang Ping Xia
  • Bryan Maloney
  • Xiao Feng Zhu
  • Junrong Ma
  • Yalou Huang
  • Helen Y Figueroa
  • Karen Duff
  • Cheng Qian
  • Min Fang
  • Jason Bailey
  • Quentin Liu
  • Karen E Duff
  • Rong Cai
  • Lihua Duan

Detail Information

Publications50

  1. ncbi request reprint NOK mediated mitogenic signaling is altered by P203L and V395I mutations
    Sheng Qi Hou
    Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Uion Medical College, Beijing 100005, China
    Front Biosci (Landmark Ed) 20:1179-89. 2015
    ....
  2. pmc Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal transducers and activators of transcription factor 3 signalin
    Wei Ye Shi
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Int J Mol Sci 14:24656-69. 2013
    ..Therefore, our data strongly indicates that IL-23R is able to induce cell apoptosis by activating the intrinsic mitochondrial pathways associated with the inhibition in RAS/MAPK and STAT3 activations in mammalian cells. ..
  3. ncbi request reprint Characterization of an upstream regulatory element of adenovirus L1 poly (A) site
    Li Liu
    Department of Microbiology and Etiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    Virology 337:124-35. 2005
    ..Transcript and gene repression mediated by the L1URE may provide a general strategy employed by adenovirus to block premature expression of late stage MLTU transcripts...
  4. doi request reprint Identification and characterization of three novel small interference RNAs that effectively down-regulate the isolated nucleocapsid gene expression of SARS coronavirus
    Ying li Cao
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, China
    Molecules 16:1544-58. 2011
    ..Our data indicate that the inhibitory effect of siRNA on the isolated N gene expression might be influenced by the sequence context around the targeted sites...
  5. pmc Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques
    Li Liu
    AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People s Republic of China
    J Virol 85:4025-30. 2011
    ..Our findings also have implications for SARS-CoV early diagnosis and prevention...
  6. doi request reprint MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway
    Rong Guo
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Molecules 17:14733-47. 2012
    ..Thus, our results demonstrated that miR491-5p could effectively target both Bcl-xL and TP53 and induce cell apoptosis independent of TP53...
  7. pmc Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway
    Wei Ye Shi
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
    Int J Mol Sci 17:. 2016
    ..These findings suggest that IFN-α may possess anti-cervical cancer capacity by activating cell apoptosis via the intrinsic mitochondrial pathway and caspase-4-related ER stress-induced pathway...
  8. pmc The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism
    Yi Wang
    Department of Microbiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China
    MBio 7:e01872-15. 2016
    ....
  9. doi request reprint microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture
    Guangwei Xu
    School of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, 5 Dongdan Santiao, Beijing 100005, China National Institute of Biological Sciences, Beijing, 7 Science Park Road, Zhongguancun Life Science Park, Changping, Beijing 102206, China
    Virology 448:247-54. 2014
    ..These data suggest that de novo HBV infection of cultured hepatocytes does not depend on the expression level of intracellular miR-122 of the target cells...
  10. ncbi request reprint Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells
    Xiang Yue Zhang
    Department of Microbiology and Etiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China
    Immunogenetics 57:934-43. 2006
    ....
  11. pmc Lentivirus-mediated silencing of Tiam1 gene influences multiple functions of a human colorectal cancer cell line
    Li Liu
    Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
    Neoplasia 8:917-24. 2006
    ..Our results suggest that Tiam1 truly plays a causal role in the metastasis of colorectal cancer and that RNAi-mediated silencing of Tiam1 may provide an opportunity to develop a new treatment strategy for colorectal cancer...
  12. ncbi request reprint A new strategy to resume the apoptosis activity of p53 in leukemia cell lines retaining wild-type p53
    Ze Jun Liu
    Leuk Res 31:1156-8. 2007
  13. ncbi request reprint 19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse
    Li Liu
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas 75390 9058, USA
    FASEB J 21:2014-9. 2007
    ..More importantly, we demonstrate for the first time the ability to differentiate wild-type and lacZ-expressing prostate tumor xenografts in mice using this approach...
  14. ncbi request reprint Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer
    Li Liu
    Department of Pathology, Southern Medical University, Tonghe Street, Guangzhou 510515, Guangdong, China
    Cell Biol Int 31:805-14. 2007
    ..These results give some clues to elucidate the mechanism of Tiam1-mediated metastasis for colorectal cancer...
  15. ncbi request reprint Differential proteomic analysis of human colorectal carcinoma cell lines metastasis-associated proteins
    Liang Zhao
    Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China
    J Cancer Res Clin Oncol 133:771-82. 2007
    ....
  16. ncbi request reprint Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
    Li Liu
    Department of Cancer Biology, Bayer HealthCare Pharmaceuticals, West Haven, Connecticut 06516, USA
    Cancer Res 66:11851-8. 2006
    ....
  17. ncbi request reprint Tetraspanin CD151 promotes cell migration by regulating integrin trafficking
    Li Liu
    Vascular Biology Center, Cancer Institute, Department of Medicine and Department of Molecular Science, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Biol Chem 282:31631-42. 2007
    ..In conclusion, the YXXvarphi motif-mediated internalization of CD151 promotes integrin-dependent cell migration by modulating the endocytosis and/or vesicular trafficking of its associated integrins...
  18. doi request reprint Protective effect of saponins from Panax notoginseng against doxorubicin-induced cardiotoxicity in mice
    Li Liu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, P R China
    Planta Med 74:203-9. 2008
    ..These results imply the potentially clinical application of PNS to overcome the negative side effects of doxorubicin...
  19. doi request reprint Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing
    Yi Wen
    Taub Institute at Columbia University Medical Center, New York State Psychiatric Institute, New York, New York 10032, USA
    J Neurosci 28:2624-32. 2008
    ..Thus, cdk5 inhibitors may not be effective in targeting tau phosphorylation in the elderly...
  20. pmc Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing
    Yi Wen
    Taub Institute at Columbia University Medical Center, New York, NY 10032, USA
    Neuron 57:680-90. 2008
    ..These data demonstrate a pathway by which p25/cdk5 increases the amyloidogenic processing of APP through STAT3-mediated transcriptional control of BACE1 that could have implications for AD pathogenesis...
  21. doi request reprint Treatment of cancer with a novel dual-targeted conditionally replicative adenovirus armed with mda-7/IL-24 gene
    Jingjing Luo
    Institute of Medicine and Biotechnology, School of Life Sciences, Zhejiang Sci Tech University, Hangzhou, Zhejiang, China
    Clin Cancer Res 14:2450-7. 2008
    ..However, better specificity and mode of transgene expression are required to improve the efficacy and safety if this vector is applied for clinical application...
  22. doi request reprint Gene delivery of indoleamine 2,3-dioxygenase prolongs cardiac allograft survival by shaping the types of T-cell responses
    Guang Yu
    Department of Immunology, Laboratory of Transplantation, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
    J Gene Med 10:754-61. 2008
    ..We investigated the hypothesis that overexpression of indoleamine 2,3-dioxygenase (IDO) by a cardiac allograft may result in a survival advantage of the allograft by creating a tolerogenic microenvironment...
  23. ncbi request reprint Exploring feasibility of multicolored CdTe quantum dots for in vitro and in vivo fluorescent imaging
    Junfeng Su
    College of Software, Nankai University, Tianjin 300071, PR China
    J Nanosci Nanotechnol 8:1174-7. 2008
    ..The studies indicate that CdTe QDs can provide alternative fluorescent probes for biological imaging...
  24. doi request reprint Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
    Xiang Bo Wan
    State Key Laboratory of Oncology in Southern China, Department of Experimental Research, Sun Yat Sen University, 651 Dongfeng Road East, Guangzhou 510060, China
    Carcinogenesis 29:1930-7. 2008
    ..Small chemical inhibitor VX-680 may offer as a promising molecular targeting agent in human NPC...
  25. pmc KAI1 gene expression in colonic carcinoma and its clinical significances
    De Hua Wu
    Department of Radiation Oncology, First Military Medical University, Guangzhou 510515, Guangdong Province, China
    World J Gastroenterol 10:2245-9. 2004
    ..To investigate KAI1 gene expression in the progression of human colonic carcinoma and its clinical significances...
  26. ncbi request reprint Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells
    Hui Zhong Zhang
    Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi an, China
    Cancer Biol Ther 5:1457-61. 2006
    ..Our study indicates that survivin gene promoter-driven stathmin siRNA expression vector may have potential use in tumor gene therapy with targeted tumor gene silencing effect...
  27. ncbi request reprint Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a possible mechanism in sporadic Wilms' tumor
    Yu Rong
    Department of Biological Sciences and Biotechnology and Institute of Biomedicine, Tsinghua University, Beijing 10084, China
    Cancer Res 66:8049-57. 2006
    ..Strikingly, STAT3 translocates to the nucleus and interacts with WT1 in a variety of primary Wilms' tumor cells, raising the hypothesis that WT1 and activated STAT3 in Wilms' tumor accelerate tumorigenesis...
  28. ncbi request reprint [Establishment of hepatic metastatic subline of nasopharyngeal carcinoma cell line]
    Chun Han
    Department of Pathology, Southern Medical University, Guangzhou 510515, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:654-7. 2006
    ..To establish a hepatic metastatic subline of nasopharyngeal carcinoma (NPC) cell line...
  29. ncbi request reprint Tetraspanin CD82 attenuates cellular morphogenesis through down-regulating integrin alpha6-mediated cell adhesion
    Bo He
    Vascular Biology Center and Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Biol Chem 280:3346-54. 2005
    ....
  30. ncbi request reprint Novel NMR platform for detecting gene transfection: synthesis and evaluation of fluorinated phenyl beta-D-galactosides with potential application for assessing LacZ gene expression
    Jianxin Yu
    Department Radiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9058, USA
    Bioconjug Chem 15:1334-41. 2004
    ..This class of molecules presents a new strategy for assaying gene expression with a highly versatile molecular structural platform...
  31. ncbi request reprint The palmitoylation of metastasis suppressor KAI1/CD82 is important for its motility- and invasiveness-inhibitory activity
    Bin Zhou
    Vascular Biology Center and Department of Medicine and Department of Molecular Science, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Cancer Res 64:7455-63. 2004
    ..Taken together, our results indicate that palmitoylation is crucial for the functional integrity of tetraspanin KAI1/CD82 during the suppression of cancer cell migration and invasion...
  32. ncbi request reprint BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    Scott M Wilhelm
    Bayer Pharmaceuticals Corporation, West Haven, Connecticut 06516, USA
    Cancer Res 64:7099-109. 2004
    ..These data demonstrate that BAY 43-9006 is a novel dual action RAF kinase and VEGFR inhibitor that targets tumor cell proliferation and tumor angiogenesis...
  33. ncbi request reprint Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice
    Jian Wu
    Transplant Research Institute, University of California Davis Medical Center, Sacramento, 95817, USA
    Hepatology 40:195-204. 2004
    ..In conclusion, polycationic liposome-mediated EC-SOD gene delivery protects against reactive oxygen species toxicity in vitro and against lipopolysaccharide-induced acute liver injury in D-galactosamine-sensitized mice...
  34. ncbi request reprint A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice
    Li Liu
    Tsinghua Institute of Genome Research, Department of Biological Sciences and Biotechnology and Institute of Biomedicine, Tsinghua University, China
    Cancer Res 64:3491-9. 2004
    ..Thus, our results both in vitro and in vivo suggest that NOK is a novel oncogene with the capacity of promoting cell transformation, tumorigenesis, and metastasis...
  35. ncbi request reprint Characterization and promoter analysis of the mouse nestin gene
    Leping Cheng
    Laboratory of Molecular Cell Biology, Laboratory of Stem Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, PR China
    FEBS Lett 565:195-202. 2004
    ..These results demonstrate an important functionality of Sp1 and Sp3 in regulating the expression of the mouse nestin gene...
  36. ncbi request reprint [Radiosensitization by pentoxifylline in human hepatoma cell line HepG2 and its mechanism]
    De Hua Wu
    Department of Radiation Oncology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 24:382-5. 2004
    ..To investigate the radiosensitization by pentoxifylline (PTX) in human hepatoma cell line HepG2 and its possible mechanism...
  37. ncbi request reprint [Effect of tumor suppressor gene KAI1 on the biological behaviors of human colorectal carcinoma]
    Li Liu
    Department of Pathology, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:587-90, 594. 2003
    ..To determine whether the expression of tumor suppressor gene KAI1 can suppress the invasive or metastatic ability of colorectal carcinoma cells...
  38. ncbi request reprint BAG5 inhibits parkin and enhances dopaminergic neuron degeneration
    Suneil K Kalia
    Applied and Interventional Research, Toronto Western Hospital Research Institute, University Health Network, University of Toronto, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    Neuron 44:931-45. 2004
    ..This contrasts with the antideath functions ascribed to BAG family members and suggests a potential role for BAG5 in promoting neurodegeneration in sporadic PD through its functional interactions with parkin and Hsp70...
  39. ncbi request reprint The second subunit of the replication factor C complex (RFC40) and the regulatory subunit (RIalpha) of protein kinase A form a protein complex promoting cell survival
    Rakhee S Gupte
    Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York 10595, USA
    Cell Cycle 4:323-9. 2005
    ..Interestingly, downregulation of endogenous RIalpha by 8-chloro cAMP, in MCF7 breast cancer cells led to reduction in the amount of RFC40-RIalpha complex, together with decrease in cell survival...
  40. pmc Tiam1 gene expression and its significance in colorectal carcinoma
    Li Liu
    Department of Pathology, First Military Medical University, Guangzhou 510515, Guangdong Province, China
    World J Gastroenterol 11:705-7. 2005
    ..To explore the expression of Tiam1 gene in colorectal carcinoma and its correlation with tumor metastasis...
  41. pmc Cell aggregation-induced FGF8 elevation is essential for P19 cell neural differentiation
    Chen Wang
    Key Laboratory of Stem Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences and Graduate School of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Mol Biol Cell 17:3075-84. 2006
    ..Blocking the bone morphogenetic protein (BMP) pathway by overexpressing Smad6 in P19 cells, we also show that FGF signaling plays a BMP inhibition-independent role in P19 cell neural differentiation...
  42. ncbi request reprint [Cytotoxicity of pentoxifylline and its effect on human hepatoma cell line Hep3b radiosensitivity]
    De Hua Wu
    Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:305-7. 2006
    ..To investigate the effects of pentoxifylline (PTX) on radiation induced-cell cycle redistribution and radiosensitivity of human hepatocellular carcinoma cell line Hep3b...
  43. ncbi request reprint [Tiam1 expression correlates with the biological behavior of human colorectal carcinoma cells]
    Li Liu
    Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China
    Zhonghua Bing Li Xue Za Zhi 34:664-8. 2005
    ..To investigate whether the Tiam1 gene expression enhances the invasive and metastatic capabilities of colorectal carcinoma cells...
  44. ncbi request reprint [On the role of liver-enriched transcription factors in regulating HBV transcription and replication]
    Song Wang
    Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 37:35-9. 2006
    ..To investigate the effects of various liver-enriched transcription factors in regulating HBV transcription and replication, and to explore their potential roles in HBV hepatotropism...
  45. ncbi request reprint [TNF-alpha mRNA expression in lung cancer cell lines induced by ionizing radiation]
    Li Liu
    Union Tumor Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430023, China
    Zhonghua Zhong Liu Za Zhi 27:347-9. 2005
    ..The aim of this study is to investigate the release of TNF-alpha mRNA in two lung cancer cell lines in vitro and the regulation of TNF-alpha mRNA expression by ionizing radiation...
  46. pmc Antitumor effects and radiosensitization of cytosine deaminase and thymidine kinase fusion suicide gene on colorectal carcinoma cells
    De Hua Wu
    Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
    World J Gastroenterol 11:3051-5. 2005
    ..To investigate the killing effect and radiosensitization of double suicide gene mediated by adenovirus on colorectal carcinoma cells...
  47. pmc The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication
    Hong Tang
    Department of Molecular Oncology, Cancer Research Institute, Kanazawa University, Takara machi 13 1, Kanazawa 920 0934, Japan
    J Virol 79:5548-56. 2005
    ..These results suggest that HBx has an important role in stimulating HBV transcription and replication and that the transcriptional transactivation function of HBx may be critical for its augmentation effect on HBV replication...
  48. ncbi request reprint Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA
    Gang Cai
    Department of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, 174 Changhai Avenue, Shanghai 200433, China
    J Mol Cell Cardiol 38:593-605. 2005
    ..It indicates the therapeutic potential of blocking T cells activation by gene-transfer in myocarditis...
  49. ncbi request reprint Differential display of proteins involved in the neural differentiation of mouse embryonic carcinoma P19 cells by comparative proteomic analysis
    Jie An
    Key Laboratory of Proteomics, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Proteomics 5:1656-68. 2005
    ..As an initial step toward unveiling the regulations involved in the commitment of pluripotent cells to a neural fate, information from this study may be helpful to uncover the molecular mechanisms of neural differentiation...
  50. ncbi request reprint Identification of a novel, embryonal carcinoma cell-associated molecule, nucling, that is up-regulated during cardiac muscle differentiation
    Takashi Sakai
    The Institute for Enzyme Research, The University of Tokushima, 3 18 15 Kuramoto cho, Tokushima, 770 8503
    J Biochem 133:429-36. 2003
    ..These results suggest that Nucling may play some role in the gene regulation of cell differentiation during embryonal development...